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Gambaran Penggunaan Antibiotik pada Pasien Sepsis Dewasa di RSUD X Jakarta Pasaribu, Donna Mesina Rosadini; William, William; Siceria, Putri Denova
Jurnal MedScientiae Vol 5 No 1 (2026): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v5i1.3753

Abstract

Sepsis is a collection of symptoms that occur as a result of an overreaction of the human immune response caused by microbes. Sepsis can progress to septic shock and if it persists accompanied by decreased immunity can cause death. Antibiotic therapy should be given as soon as the diagnosis, starting with empiric antibiotics which are then adjusted according to clinical response or culture results. This study aims to describe the use of antibiotics in RSUD X Jakarta, in adult sepsis cases. The research method is descriptive observational with consecutive sampling in accordance with the inclusion and exclusion criteria. Data collection was obtained through medical records of patients diagnosed with sepsis. The results showed that the most patients sepsis were aged less than 60 years, there were 51%, men 53%, the length of stay was less than 10 days, 62% and 55% patients had no comorbidities. The focus of infection was mostly in the lungs 38%, patients who sampled the most monotherapy antibiotics were Ceftriaxone 51.1%, the most combination use was Levofloxacin and Meropenem 21.1%, and the longest duration of antibiotic use less than 7 days with Ceftriaxone 43 (53.75%). There were 64 people (64%) of these sepsis patients died. The study concluded that the focus of infection in sepsis patients was mostly in the lungs, men aged less than 60 years, without any comorbid disease, length of stay less than 10 days. The choice of antibiotic monotherapy for septic patients, given Ceftriaxone, for combination therapy given Levofloxacin and Meropenem antibiotics.
PENGARUH LEVERAGE, LIKUIDITAS DAN UKURAN PERUSAHAAN TERHADAP PROFITABILITAS (Studi Kasus Pada Sektor Perusahaan Food and Beverage Yang Terdaftar di Bursa Efek Indonesia Periode 2017-2021) William, William
Jurnal KIAFE Vol. 1 No. 2 (2023): JURNAL KAJIAN ILMIAH AKUNTANSI
Publisher : Undergraduate Program in Accounting, Department of Accounting, Faculty of Economics and Business, Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/kiafe.v1i2.72316

Abstract

This study aims to examine and analyze the effect of leverage, liquidity and company size on profitability in food and beverage companies for the 2017-2021 period. The data analysis technique used is panel regression analysis. The data used is sourced from the Indonesia Stock Exchange which consists of 35 food and beverage companies. The results of the data analysis show that leverage has a positive and significant effect on profitability, liquidity has a positive and significant effect on profitability and firm size has a negative and significant effect on profitability.
Penggunaan Antibiotik pada ISPA Gambaran Penggunaan Antibiotik pada Anak Dibawah Usia Lima Tahun (Balita) dengan Infeksi Saluran Pernapasan Akut (ISPA) di Puskesmas Kelurahan Tanjung Duren Selatan Tahun 2020-2021: Antibiotik pada ISPA Balita William, William; Wijaya, Axel Thio; Pasaribu, Donna Mesina; Hudyono, Johannes
Jurnal MedScientiae Vol 1 No 2 (2022): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscie.v1i2.2510

Abstract

Acute respiratory infections (ARI) is a disease that attacks the respiratory tract with various symptoms. The biggest cause of ARI is a virus (90-95%), so there is no need for antibiotics because most of the causes of ISP are viruses. Irrational administration of antibiotics can lead to bacterial resistance. The purpose of this study was to describe the use of antibiotics in infants under five years of age with ARI at the Tanjung Duren Selatan Village Health Center in the 2020-2021 period. This research was conducted by descriptive observational on 50 subjects. Sampling by consecutive sampling. The results of this study indicate that the majority of ARI patients have cough symptoms (96%) with an age range of 1-3 years (52%) and birth weight < 15 kg (92%). Complete basic immunization status is only 30%. Most of children under five with ARI (80%) did not get antibiotics and as many as 20% of patients under five with ARI used antibiotics, namely amoxicillin. This study concluded that according to the etiology of ARI in children under five caused by a virus, most of the Toddler patients with ARI  not receive antibiotics (80%) and Toddlers who used antibiotics (20%).
Hubungan Kebisingan dengan Kadar Glukosa Darah pada Manusia : Sebuah Review Rumiati, Flora; Lailossa, Alfredo Lasiata; William, William; Winata, Susanty Dewi
Jurnal MedScientiae Vol 1 No 2 (2022): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscie.v1i2.2632

Abstract

Noise is a sound whose presence is unwanted that it has an impact on health problems, an uncomfortable environment and can cause deafness. The impact of noise on health can occur in workplace and cause disturbances that are classified in stages. Several studies have found that sudden exposure to sound causes physiological reactions such as pulse, blood pressure, metabolism, sleep disturbances and constriction of blood vessels. The search for research journal articles was obtained from publication media, filtered from inclusion and exclusion criteria and obtained 10 journals to be reviewed. The results of this study are that in all the articles reviewed by the author there is a relationship between long-term noise exposure and human blood glucose levels. Noise exposure led to increased phosphorylation of jnk (c-Jun N-terminal kinase) as well as decreased phosphorylation in skeletal muscle in response to exogenous insulin stimulation, and another result was that plasma levels of TNF-α and IL-6 in skeletal muscle increased after long-term noise exposure. Noise exposure also causes dysregulation of the activity of the hypothalamo-pituitary adrenal axis with high corticosterone, which appears to blunt insulin action in peripheral tissues, consequently limiting glucose uptake and glycogen deposition in the liver and gastrocnemius muscle.
Efektivitas Kompres Jahe pada Lanjut Usia Penderita Nyeri Osteoarthritis Rumiati, Flora; Meistika, Gabriel; Heriyanto, Heriyanto; William, William
Jurnal MedScientiae Vol 1 No 2 (2022): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscie.v1i2.2644

Abstract

Cartilage in the knee of the foot will gradually thin out with age and increase the load on the footstool. The cartilage in the knee is called the meniscus which is useful for protecting the surrounding bones from rubbing against each other when moving. When the meniscus thin and rub against each other will cause pain and the sound of crepitus when walking. Pain is an uncomfortable condition due to physical stimulation that is channeled to the brain followed by physical to emotional reactions. Osteoarthritis is a joint disease that causes decreased joint motion due to pain. This joint disorder most commonly occurs in the knee. Warm ginger compress therapy will make blood vessels widen or open and blood circulation to be smooth. The method of making this literature is in the form of a descriptive approach that looks for various journals or research articles with the same research theme. The results obtained with 10 journals, with the same discussion. Where in several journals get results that are proven to be effective. It can be concluded that warm ginger compresses are effective for reducing pain in osteoarthritis.
Penggunaan Tanaman Herbal Bawang Putih (Allium Sativum L) Terhadap Aterosklerosis Penyebab Penyakit Jantung Koroner Manufandu, Gracea S; William, William; Wibowo, William
Jurnal MedScientiae Vol 2 No 3 (2023): December
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i3.3016

Abstract

Background: DKI Jakarta has the highest CAD disease rate at 1.9% based on the 2018 Riskesdas. Deaths from CAD are predicted to increase to 23.3 by 2030. Atherosclerosis is an inflammation that occurs due to the deposition of fat called atheroma. Currently, many studies are conducted to reduce cholesterol levels in the blood using natural ingredients such as garlic which is considered to have many advantages. The purpose of this study is to determine the important compounds in garlic that can reduce cholesterol levels, and become anti-atherosclerosis in blood vessels. Methods: Literature review based on articles and journals adjusted by PICO (Population, Intervention, Control, Outcome) and PRISMA Flow Diagram Generator method. Journals were searched in medical databases through Google Scholar, PubMed, and ProQuestd. Results: Based on the literature, garlic compounds that can reduce LDL levels and increase HDL have been studied, namely non-volatile γ-glutamyl-Salk(en)yl-L-cysteine or alliin . Conclusion: The presence of active compounds contained in garlic can significantly reduce the risk of atherosclerosis in coronary heart disease because it can reduce cholesterol levels in the blood and plaque in atherosclerosis.
Gambaran Penderita Batu Empedu Di RSUD Tarakan Melalui Pemeriksaan Ultrasonografi Molle, Michel; Rumawas, Marina Astrid; Sutrisno, Sony; William, William
Jurnal MedScientiae Vol 5 No 2 (2026): August
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v5i2.4473

Abstract

Gallstones form from deposits of bile within the gallbladder. Gallstones can be detected via ultrasound examination to assess Murphy’s sign. Data on the incidence of gallstones in Indonesia itself is currently insufficient. This study aims to determine the profile of gallstone patients and their characteristics through  ultrasound examinations as well as their management at Tarakan Regional General Hospital. A descriptive cross-sectional study design using total sampling was applied to medical records from 2023. A sample of 97 individuals meeting the inclusion and exclusion criteria was obtained. The results are presented in tables and diagrams. A total of 64 patients (66.0%) were female, and 64 patients (66.1%) were aged 40 years or older. The group with a single stone was found in 78 patients (80.8%), whilst the highest frequency was observed in patients with medium-sized stones (5–10 mm), comprising 61 patients (62.89%). It can be concluded that patients with cholelithiasis at Tarakan General Hospital are more commonly found among women aged 40 years or older with medium-sized stones. The effectiveness of ursodeoxycholic acid in 12 patients could not be evaluated due to incomplete data. Meanwhile, surgical intervention for gallstone patients is based more on the onset of complaints or clinical symptoms, rather than on the size and number of gallstones.
Co-Authors , Rahima Br Purba A.A. Ketut Agung Cahyawan W Adi Neka Fatyandri Agatha, Nabila Agustinus Agustinus Ako, Ayu Syarbani Alfian, Achmad Alvina, June Ana Lucia Ekowati Anderes Gui, Anderes Andrean , Lawrence Angellee, Jesselyn Anggara, Alfin Arie Pratania Putri Arrafif, Rifqi Arruda Supinto, Pedro Aulia Qadri, Rizni Azmi, Fadhillah bah, Yasavati Kurnia Bambang Subiyanto Barus, Okky Putra Bryan, Gaffrendo Cennikon Pakpahan Chai, Silvia Revalina Damanik, Dennys Paulus Parlindungan Daniel Ardian Soeselo Darius Andana, Darius Deli Desak Putu Ariska Pradnya Dewi Diny Donna Mesina Rosadini Pasaribu Eldy, Eldy Erandaru Erandaru Fatiha , Senna Sayyid Ferbian Milas Siswanto Flora Rumiati Florence Statriani, Putu Denisa Fortino, Edbert Franco , Franco Gabriella Susanto, Nadya Gebril, Steven Ginting , Rio Sanjaya Gizella, Gizella Gunawan Gunawan Harahap, Nurajdina Hardi, Nicholas Hartanto, Markus Christian Hartanto, Tommy Tiara Heriyanto Heriyanto Holanda, Stevanny Ida Ayu Putu Sri Widnyani Indrati , Menik Indriani Kurniadi Sumadikarya Inneke Kusumawati Susanto Iqlima, Iqlima Iqlima, Nur Alniz Itanza, Vionita Jeanny Pragantha Jennyfer, Jennyfer Jessica Kurnia Niaga, Karmenia Joe, Sherly Johan, Monika Evelin Johannes Hudyono Johny Budiman Jolyn , Jolyn Katherine Kho Khang , Jackie Khesi, Khesi Kinadi, Febriana Lailossa, Alfredo Lasiata Lie, Les Lim, Jeksen Listia Natadjaja Lubis, Abdul Rahman Mahariska, Dina Fitria Mahatmaputra, Samuel Manufandu, Gracea S Marcel Antoni Maria Dara Novi Handayani, Maria Dara Novi Marpaung, Fenny Krisna Maryanie Maryanie, Maryanie Maryati Maryati Mas, Muhammad Abdurrahman Mawaddah Harahap, Mawaddah Meistika, Gabriel Melvin Octorian, Melvin Melyana Melyana Michelle , Michelle Molle, Michel Nababan, Darsono Narulita, Pety Nayottama, Vicky Nelson Ng, Selina. Nialindawaty, Nialindawaty Oktasari , Stephani Pangaribuan, Jefri Junifer Pasaribu, Donna Mesina Permata, Erwin Pradesta Varro, M. Hafish Pradnyaswari, Ida Ayu Ketut Andriyogi Priadi, Dina Puspita Purba, Tiurniari Purnasari, Nina Putri, Fransiska Minerva Rahma, Sonia Rahmadanty, Nadiya Kamila Rickie, Rickie Rico, Rico Romindo Rumawas, Marina Astrid S. Sugiharto Safitri , Ariska Salim, Kevin Kristanto Saputra, Vandi Sari, Ike Rukmana Satriabudi, Mirza Indrajanti Selina. Ng, Selina. Ng Senarto, Clifton Serly, Serly Siceria, Putri Denova Sihombing, Josua Parulian Simanjuntak, Demak Claudia Yosephine Stefhanny, Stefhanny Suharyani, Sally Sulia Sulia Surjawan, Iwan Susanty Dewi Winata Sutrisno, Sony Tahnia, Rizky Putra Tanardi, Samantha Tanojo, Jonathan Isaac Tanojo, Tjahjo Djojo Tarigan, Purnaya Sari Telaumbanua, Syahputra Teny Handhayani Tham, Felix Thauwrisan, Bryant Anthony Tio, Collin Tya Wildana Hapsari Lubis Utomo, Natasha Susanto Veblyn, Veblyn Velicia, Paula Wibowo, William Wijaya, Alvin Wijaya, Axel Thio Willim, Raymond Yo, Rivan Yosua Setyawan Soekamto Yuda Turana Zai, Immanuel