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Journal : Buletin Farmatera

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Administration Of Emprit Ginger Extract (Zingiber Officinale Rosc.) Effect On Cholesterol Reduction In Students Suffering From Hypercholesterolemia Pasaribu, Ummi Rachmi; Yenita, Yenita
Buletin Farmatera Vol 10, No 2 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i2.24414

Abstract

Abstract: Hypercholesterolemia is one of the lipid disorders that is usually characterized by an increase in cholesterol levels in the blood to above 200 mg/dL. The prevalence of hypercholesterolemia in the world is around 45% while in Southeast Asia it is around 30% and in Indonesia it reaches 35%. Currently, people with hypercholesterolemia are not only adults or the elderly, but many children and adolescents have experienced hypercholesterolemia due to their lifestyle. Emprit ginger (Zingiber officinale Rosc.) or small ginger is a ginger used for spices, beverage raw materials, and herbal medicine. The main ingredients in ginger are shogaol and gingerol which are flavonoid compounds. The decrease in cholesterol levels is influenced by flavonoid and polyphenol compounds that prevent free radicals, have a hypocholesterol effect that inhibits the enzyme HMG-CoA reductase.  This study aims to find out whether ginger emprit can lower cholesterol levels in students suffering from hypercholesterolemia. The research method used was quantitative with a research design using pre-experimental (pretest and posttest) on 61 people suffering from hypercholesterolemia and a statistical wilcoxon test will be performed. It was found that 61 students had hypercholesterol and 36 of them had decreased to normal after consuming emprit ginger extract. This result is supported by statistical analysis using the Wilcoxon method with a p-value of 0.000 (p 0.05).  It can be concluded with a p-value of 0.000 that the administration of emprit ginger extract has the potential to have a significant influence on students suffering from hypercholesterolemi
Co-Authors Adelia Rachmita, Prima Adrial Adrial, Adrial Afdol Rahmadi Afriani Agus Arijanto Anggrainy, Fenty Anindita, Reza Yoga Aswiyanti Asri Aswiyanti Asri Aswiyanti, Asri Azzahra Saidah Ramadhani C. Catur Widayati Cintalia, Meivina Daan Khambri Daan, Khambri Dariyani, Nuriz Defrin Defrin Dharmaji Chowmas Dini Andri Utami Dwi Yanti Fioni Putri Effendi, Hernita Etriyel Myh Fachry Abda El Rahman Hardian, Sonny Hardisman Harsby, Carmiyana Puja Hasmiwati Hendriani, Intania Dwiputri henny Mulyani Henny Mulyani Henny, Mulyani Hera Novianti Herawati, Destiana Herdiansyah, Januar Hermafasya, Ayu Octarin Hidayat, Nur Latifah Alfaina Husna Yetti Husna, Yetty Iftahillah Ismet Ismet, Ismet Isra Thristy Johan Kurnianda Ketang Wiyono Leonard, Randy liana, nana Loli Devianti M.Yoga Sefia Nurindra Maisa, Kamilah Nada Mayorita, Pamelia Meilinda Meilinda Monika Muhammad Fajar Musyarifah, Zulda Nanda, Cici Bayu Nita Afriani Noza Hilbertina Noza Hilbertina, Noza Noza, Hilbertina Nur Aristiani, Prita Nurfadly, Nurfadly Nursasi, Harnah Pasaribu, Ummi Rachmi Pemuda, Haris Purnamawati Hellen Widjaja Putri, Ratih Elsa R. Zuryati Nizar Rahmatina B Herman Ratih Kusumawardani Ratna Purwaningsih Ria Oktavia Ria Oktavia Rizanda Machmud Rizki Saputra Rizky Kurniawan Rony Rustam Salmiah Agus Salmiah Agus Sari, Rini Purnama Sembiring, Ranggi Heryagung Septia Haryani Setiadi, Fredrick Setiawati, Yessy Sofie, Femmy Sondang, Nora Sophian, Alfi Sri Utaminingsih Suchitra, Avit Sukri Rahman Suryati Suryati Susetyowati Syamel Muhammad Syamsiar, Syamsiar Tofrizal Triani, Ririn Agus Utami, Dini Andri Vitro Darma Yusra Wijaya, Septihani Michella Wildanur, Sri Yadi Sutikno Yaslinda Yaunin Yulistini, Yulistini Yuliza Ariani Yuniar Lestari Yusrawati Yusrawati