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All Journal Jurnal Kesehatan Andalas INDONESIAN JOURNAL OF PHARMACY Universa Medicina Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Buletin Ilmiah Nagari Membangun Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Sumatera Medical Journal Indonesian Journal of Health Sciences Research and Development (IJHSRD) Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Kesehatan Indonesia (JIKSI) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Consilium Sanitatis: Journal of Health Science and Policy
Dwitya Elvira, Dwitya
Fakultas Kedokteran Universitas Andalas
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

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Perbedaan Rerata Kadar Albumin Pasien Lupus Eritematosus Sistemik berdasarkan Derajat Aktivitas Penyakit di RSUP Dr. M. Djamil Padang Ulti, Zifa Amanda; Elvira, Dwitya; Firdawati; Efrida; Raveinal; Aliska, Gestina
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 4 (2025): Desember 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i4.1478

Abstract

Latar Belakang: Lupus Eritematosus Sistemik (LES) adalah penyakit autoimun kompleks yang dapat menyerang berbagai pertahanan sistem tubuh. Penyakit ini berhubungan dengan pembentukkan autoantibodi sehingga dapat menyebabkan inflamasi kronis yang berujung pada kerusakkan jaringan tubuh. Aktivitas Penyakit LES diduga dapat mempengaruhi kadar albumin di dalam tubuh.    Objektif: Penelitian ini bertujuan untuk mengetahui apakah terdapat perbedaan rerata kadar albumin pasien LES berdasarkan derajat aktivitas penyakit di RS M. Djamil Padang. Metode: Penelitian ini menggunakan metode analitik dengan pendekatan cross-sectional study. Sampel penelitian berjumlah 59 pasien LES rawat jalan dan rawat inap di RS M. Djamil Padang yang dikumpulkan secara consecutive sampling. Analisis data penelitian menggunakan uji one way annova. Hasil: Pada penelitian ini didapatkan mayoritas pasien LES berada di rentang usia 26−35 tahun (44,1%), berjenis kelamin perempuan (100%). Lebih dari setengah pasien LES mengalami hipoalbuminemia (76,3%), sebagian besar pasien memiliki derajat aktivitas penyakit sedang (39%). Rerata kadar albumin terendah ditemukan pada pasien dengan derajat aktivitas penyakit berat sebesar 2,25 g/dL. Kesimpulan: Terdapat perbedaan yang bermakna pada rerata kadar albumin pasien LES. Rerata kadar albumin terendah pasien LES ada pada kelompok derajat aktivitas penyakit berat. Rerata kadar albumin tertinggi pasien LES ada pada kelompok derajat aktivitas penyakit ringan.
Diagnostic value of Peguero-Lo Presti electrocardiographic criteria for diagnosing concentric left ventricular hypertrophy in hypertensive patients at Dr. M. Djamil General Hospital Padang Poedjijo, Yanuar Surya Saputra; Hanif, Akmal M.; Wahyudi; Murni, Arina Widya; Ahmad, Armen; Faheri, Eifel; Elvira, Dwitya; Kurniawan, Eka
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 3, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss3.art5

Abstract

Background: Hypertension is a risk factor for morbidity and mortality from cardiovascular disease. Left ventricular hypertrophy (LVH) is the main target organ due to hypertension, which is a predictor of the development of cardiovascular diseases such as heart failure. Echocardiography is the gold standard examination for determining heart geometry, and concentric LVH is often found in hypertensive patients. Electrocardiography (ECG) is a widely available, low-cost, and rapid modality for diagnosing LVH in healthcare facilities. The Peguero–Lo Presti (PLP) criteria in ECG examination have better sensitivity and specificity compared to other criteria. Objectives: This study aims to determine the diagnostic value of PLP ECG to diagnose concentric LVH.Methods: This research is an analytical observational study with a cross-sectional approach carried out at the inpatient installation of Dr. M. Djamil General Hospital Padang for 6 months, starting from April to September 2024. The study subjects who met the inclusion and exclusion criteria were 90 samples selected by consecutive sampling. An ECG examination was conducted using PLP criteria and echocardiography with the M-mode method to assess left ventricle (LV) geometry. Data were analysed using a 2x2 table to obtain sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy.Results: From 90 samples, LVH geometry was found concentric in 65.50%, eccentric 4.40%, concentric remodelling 11.10%, and normal 18.90%. In the diagnostic test, PLP criteria had 79.66% sensitivity, 90.32% specificity, 94.00% PPV, 70.00% NPV, and 83.33% accuracy to diagnose concentric LVH in hypertensive patients.Conclusion: Peguero Lo-Presti criteria on ECG can be used for screening and early diagnosis of concentric LVH in hypertensive patients.
FACTORS ASSOCIATED WITH MORTALITY OF ELDERLY PATIENTS WITH COVID-19 INFECTION AT M. DJAMIL HOSPITAL, PADANG, WEST SUMATRA, INDONESIA : COVID-19 INFECTION Mulyana, Roza; Elvira, Dwitya; Martini, Rose Dinda
INDONESIAN JOURNAL OF HEALTH SCIENCES RESEARCH AND DEVELOPMENT (IJHSRD) Vol. 7 No. 2 (2025): INDONESIAN JOURNAL OF HEALTH SCIENCES RESEARCH AND DEVELOPMENT
Publisher : STIKes Mandala Waluya Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36566/ijhsrd/Vol7.Iss2/329

Abstract

Background: To analyze the factors influencing the mortality incidence of elderly patients with COVID-19 infection in Padang, West Sumatra, Indonesia. Methods: This is a retrospective study at M. Djamil Hospital, Padang. Data was collected from the medical records of COVID-19 patients treated during July-September 2021. Results: Of the 243 elderly patients who experienced COVID-19, the most deaths were male (58.6%) with an average age of 69.64 ± 7.74 years. Multivariate analysis showed that patients with critical-severe clinical symptoms (odds ratio (OR) 12.95; 95% confidence interval (CI) 6.66–25.19), heart disease (OR 6.94; 95% CI 1.63–29.60), respiratory rate ≥30 breaths per minute (OR 3.48; 95% CI 1.04–11.60), pulse ≥100 beats per minute (OR 2.88; 95% CI 1.03–8.04), using a ventilator or high-flow nasal cannula (OR 19.78; 95% CI 5.92–66.10), prothrombin time >13.16 second (OR 12.35; 95% CI 2.43–62.77), interleukin-6 >6 pg/mL (OR 15.19; 95%CI 2.53–91.26), and random blood glucose >199 mg/dL (OR 3.45; 95% CI 1.02–11.68) have a high risk of death. Conclusion: Elderly patients with COVID-19 infection with critical-severe clinical symptoms accompanied by heart disease, using ventilator or high-flow nasal cannula, longer prothrombin time, high level of interleukin-6, and random blood glucose have higher risk of mortality.
Cerebral Toxoplasmosis and Latent Tuberculosis Infection in HIV Infected Patient Rijalun Arridho; Raveinal; Dwitya Elvira
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.11843

Abstract

Background: Toxoplasmosis is an opportunistic infection caused by Toxopasma gondii, which affects one third of the global human population and commonly involves the central nervous system (CNS)/brain. The diagnosis of obvious sign of imaging method cerebral toxoplasmosis is commonly reported in several case report, but subclinical sign of imaging is uncommon reported. Objective: we reported a case of 28-years-old male with chief complaint headache that worsening since 3 days before admission. Methods: This is a case report. Results: He was first recognized as HIV infected patient on hospital admission. CT scan revealed minimal perifocal oedema in left frontal region. Patient was diagnosed as cerebral toxoplasmosis and latent tuberculosis infection in HIV clinical stadium IV. Patient recieved empirical therapy of cerebral toxoplasmosis and symptom relieved after 7 days of treatment. Cerebral toxoplasmosisis typically associated with HIV infected patient that result in the reactivation of Toxoplasma gondii infection. Conclusions: Clinical presentation of CNS toxoplasmosis varies and normal brain CT can be found despited presumptive diagnosis was revealed.
Co-Authors Abdiana Addina, Azka Adrial Adrial Ahmad, Armen Akmal M. Hanif Akmal, Elfi Fauzana Alexander Kam Alexander Kam Almurdi Almurdi Amirah Zatil Izzah Aprilia, Dinda Arina Widya Murni Arnelis . Azia Putri Al Jamil Citra Manela Deddy Saputra Deka Viotra Delfin, Muhamad Dian Pertiwi Dinda Aprilia Efrida Efrida Efrida Elvia Fataya Eva Decroli Fadrian, Fadrian Faheri, Eifel Firdawati Fortuna, Fory Gestina Aliska Gustia Anugrahwati Gustin, Hanna Hendriati, Hendriati Herinda, Dwi Putri Herman, Deddy Ilmiawati, Ilmiawati Jannah, Lidya Raudhatul Julizar Kurniawan, Eka Linosefa Linosefa Malinda Meinapuri masri, Raveinal Muhamad Delfin Muhammad Iqbal Andreas Mustafa Noer Mustafa Noer Nadia, Rizka Netti Suharti Netti Suharti, Netti Noverika Windasari Paishal Mizan Poedjijo, Yanuar Saputra Poedjijo, Yanuar Surya Saputra Rahayuningsih, Sri Puji Rahmadina, Rahmadina Rahmadina, Rahmadina Ramadanti, Zilhadia Mona Raveinal Raveinal Raveinal Raveinal Raveinal Raveinal RAVEINAL RAVEINAL Rido Wandrivel Rijalun Arridho Rikarni Rikarni Rini Gusya Liza, Rini Gusya Rismawati Yaswir Rizka Nadia Rizqy Auliya Lubis Rose Dinda Martini Roza Kurniati Roza Kurniati Roza Kurniati Roza Mulyana RR. Ella Evrita Hestiandari Rudy Afriant Russilawati, Russilawati Saptino Miro Saptino Miro, Saptino Saputra Poedjijo, Yanuar Surya Siti Nurhajjah Steven, Rios Suci Maulida Syandrez Prima Putra Ulti, Zifa Amanda Vesri Yoga WAHYUDI Wahyudi . Yuliarni Syafrita Yulistini, Yulistini zahra salsabila Zelly Dia Rofinda