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All Journal Jurnal Kesehatan Andalas INDONESIAN JOURNAL OF PHARMACY Universa Medicina Jurnal Biologi Tropis Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Buletin Ilmiah Nagari Membangun Majalah Kedokteran Andalas Sumatera Medical Journal Indonesian Journal of Kidney and Hypertension Jurnal Ners Indonesian Journal of Health Sciences Research and Development (IJHSRD) Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Kesehatan Indonesia (JIKSI) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Indonesian Journal of Cancer SENTRI: Jurnal Riset Ilmiah The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Consilium Sanitatis: Journal of Health Science and Policy Jurnal Riset Ilmiah Public Health Journal
Dwitya Elvira, Dwitya
Fakultas Kedokteran Universitas Andalas
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Profil Pasien Lupus Eritematosus Sistemik di RSUP Dr. M. Djamil Padang Tahun 2020-2021 Elfi Fauzana Akmal; Dwitya Elvira; Noverika Windasari; Malinda Meinapuri; Raveinal Raveinal; Yulistini Yulistini
Consilium Sanitatis: Journal of Health Science and Policy Vol. 2 No. 2 (2024)
Publisher : EDUPEDIA Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56855/jhsp.v2i2.1867

Abstract

Objective: To understand the profile of SLE patients at RSUP.Dr.M.Djamil Padang period of 2020-2021. Methods: The research is a descriptive type with a retrospective approach. Medical record data were collected using total sampling technique,189 samples met the inclusion criteria. Data analysis using Microsoft Excel. Results: The study found that the majority of characteristics include female patients (95.8%), age group 17-25 years (33.9%), housewives (41.8%), medium-level education (66.1%), and of Minangkabau ethnicity (86.8%). Most patients had a disease duration of ≥ 2 years (78.8%), mild disease activity (36%), the most common clinical manifestation being mucocutaneous involvement (82%). ANA Profile results, the most prevalent finding was positive dsDNA (25.4%). Patients meeting ACR 1997 criteria were 57.1%, SLICC 2012 35.4%, and EULAR 2019 10.6%. The most frequently therapy was a combination of HCQ and glucocorticoids (45%), while the most common patient outcome was survival (96.8%). Conclusion: Majority of SLE patients at RSUP Dr.M.Djamil Padang are in the productive age group with mild disease activity. The majority of patients have good outcome, indicating a favorable prognosis for SLE at RSUP Dr. M. Djamil Padang.
Diagnostic Value of Urinary Kidney Injury Molecule-1 in Diagnosis of Sepsis Associated Acute Kidney Injury Puti Anggun Sari; Drajad Priyono; Harnavi Harun; Deka Viotra; Najirman Najirman; Fauzar Fauzar; Dwitya Elvira; Arina Widya Murni
Indonesian Journal of Kidney and Hypertension Vol 3 No 2 (2026): Volume 3 No. 2 August 2026
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v3i2.263

Abstract

Abstract Background: Sepsis asscociated acute kidney injury (SA-AKI) is common condition that found in sepsis. Due to the lack of creatinine serum, this condition possibly makes therapy delayed. Kidney Injury Molecule-1 (KIM-1) is a a type 1 transmembrane protein with immunoglobulin and mucin domains, which is expressed increased in the proximal tubules of the kidney. Elevated urinary KIM-1 levels are an indicator of AKI. However, previous studies have shown varies results. Objectives: This study aims to determine early diagnosis biomarkers for the presence of AKI in sepsis. Methods: This diagnostic test was conducted at Dr. M. Djamil General Hospital Padang in sepsis patients. The diagnosis of AKI was established based on the 2012 KDIGO criteria. Results: The study involved 94 sepsis patients, only 22,34% (n=21) of them experienced AKI. Serum creatinine levels at admission and within 48 hours of hospitalization were 0,7 (IQR 0,2-1,6) mg/dl and 0,8 (IQR 0,3-2,2m) mg/dl. An urinary KIM-1 level at admission ≥11,74 ng/mL had sensitivity of 44,68%, specificity of 59,57%, positive predictive value of 52,5%, negative predictive value of 51,85%, and accuracy of 52,12% in early diagnosis of AKI in sepsis. Conclusion: Urinary Kidney injury molecule-1 level has poor diagnostic value in diagnosis of AKI in sepsis. Keywords: Sepsis, Kidney injury molecule-1, AKI.
Detection of Intestinal Protozoa Using Direct Stool Examination in Patients with Colorectal Diseases at Dr. M. Djamil General Hospital, Padang: Intestinal Protozoa in Colorectal Diseases Tazkia Aulia Permata Helena; Selfi Renita Rusjdi; Eka Kurniawan; Hasmiwati Hasmiwati; Dwitya Elvira; Shinta Ayu Intan
Indonesian Journal of Cancer Vol. 20 No. 3 (2026): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v20i3.1605

Abstract

Background: Colorectal diseases are conditions that affect the colon and rectum, impacting both their functional and structural integrity. Colorectal diseases include inflammatory bowel disease (IBD), colorectal polyps, and colorectal cancer, as they have the potential to cause chronic inflammation in the colon and rectum. Chronic inflammation and mucosal disruption may facilitate protozoan colonization and infection, potentially increasing susceptibility to intestinal protozoa. Conversely, intestinal protozoan infections may promote intestinal inflammation and epithelial damage, potentially contributing to the pathogenesis of colorectal disease. This study explores multiple colorectal diseases such as IBD, polyps, and cancer to provide a broader understanding of intestinal protozoan infections within the colorectal spectrum in West Sumatera, where such data have not been previously reported. This study aimed to determine the prevalence of intestinal protozoa detected by direct stool examination among patients with colorectal diseases at Dr. M. Djamil General Hospital Padang. Methods: This study is a descriptive cross-sectional study using primary data from a total of 73 colorectal disease patients, selected through consecutive sampling. Patient diagnoses were obtained from medical records, while intestinal protozoan infections were identified through stool samples via direct stool examination. Fresh stool samples were examined microscopically and then stained with Lugol’s iodine and eosin. Microscopic observations were performed using a binocular light microscope under 100x, 400x, and 1,000x magnifications. The study employed univariate analysis and presented the results in frequency distribution tables. This study was conducted at Dr. M. Djamil General Hospital Padang and the Parasitology Laboratory, Faculty of Medicine, Andalas University, between December 2023 and February 2024. Results: Among the 73 patients, 79,5% had colorectal cancer, 19.2% had IBD, and 1.4% had colorectal polyps. Intestinal protozoan infections were most frequently observed in patients with colorectal cancer. Most patients were male (60.3%), with the highest prevalence in the 51-60 and > 60 age groups (31.5%). Intestinal protozoan infections were detected in 52.1% (38/73) of colorectal disease patients, with Cryptosporidium sp. found in 52.6% and Blastocystis sp. in 47.4% of cases. The infection rate was higher in the 51-60 age group (36.8%) and predominantly found in males (65.8%). The dominant type of infection was single infection (89.5%). Conclusions: The prevalence of intestinal protozoan infections was found to be relatively high, particularly in colorectal cancer patients. The most frequently detected species were Blastocystis sp. and Cryptosporidium sp. Patients should undergo screening and receive antiparasitic treatment if necessary, along with education on disease prevention related to intestinal protozoan infections.  
Hubungan Hemoglobin dengan Ureum dan Kreatinin pada Pasien Penyakit Ginjal Kronik Stadium 5 di RS M. Djamil Padang Fadhla, Azizah; Pertiwi, Dian; Zulfiqar, Yevri; Husni, Husni; Elvira, Dwitya; Rahmatini, Rahmatini
Public Health Journal Vol. 3 No. 4 (2026): In Progress
Publisher : Teewan Journal Solutions

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62710/mg2x5p32

Abstract

Penyakit ginjal kronik (PGK) stadium 5 ditandai penurunan fungsi filtrasi ginjal yang dapat meningkatkan kadar ureum dan kreatinin serta disertai anemia akibat gangguan produksi eritropoietin dan faktor lainnya. Penelitian ini bertujuan menganalisis hubungan kadar hemoglobin dengan ureum dan kreatinin serum pada pasien PGK stadium 5 di RSUP Dr. M. Djamil Padang. Penelitian kuantitatif analitik dengan desain potong lintang ini melibatkan 144 pasien yang dipilih menggunakan consecutive sampling. Data diperoleh dari rekam medis pasien yang menjalani hemodialisis pertama pada Januari–Maret 2024. Pengumpulan data dilakukan pada 5–22 November 2024. Kadar hemoglobin, ureum, dan kreatinin diambil dari pemeriksaan sebelum hemodialisis pertama, kemudian dianalisis menggunakan uji korelasi Pearson. Kelompok usia terbanyak adalah 45–54 tahun (27,8%), sebanyak 53,5% pasien laki-laki, dan 48,6% memiliki hipertensi tanpa diabetes melitus. Rerata hemoglobin, ureum, dan kreatinin berturut-turut sebesar 8,2 ± 1,7 g/dL, 202,3 ± 86,7 mg/dL, dan 9,4 ± 5,4 mg/dL. Terdapat korelasi negatif bermakna antara hemoglobin dan ureum (r = −0,567; p < 0,001) serta hemoglobin dan kreatinin (r = −0,617; p < 0,001). Hasil ini menunjukkan bahwa kadar hemoglobin yang lebih rendah berkaitan dengan kadar ureum dan kreatinin yang lebih tinggi, tanpa membuktikan hubungan sebab-akibat.
Perbedaan Karakteristik, Gejala Klinis, dan Tingkat Keparahan pada pasien COVID-19 dengan komorbid DM tipe 2 dan Non DM tipe 2 di RS Universitas Andalas Zaky Athila Naufal; Dwitya Elvira; Yenita Yenita; Roza Mulyana; Syandrez Prima Putra; Elfira Yusri
Majalah Kedokteran Andalas Vol. 49 No. 1 (2026): MKA April 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v49.i1.p1-8.2026

Abstract

Tujuan: Untuk mengetahui perbedaan karakteristik, gejala klinis dan tingkat keparahan pasien COVID-19 dengan komorbid DM tipe 2 dan non-DM tipe 2 di RS. Unand; Metode: Jenis penelitian ini adalah observasional dengan pendekatan cross-sectional menggunakan seluruh data rekam medis pasien COVID-19 dengan komorbid DM tipe 2 dan Non-DM tipe 2 yang dirawat di Rumah Sakit Universitas Andalas periode Juni-Agustus 2021. Penelitian ini terdiri atas 179 sampel menggunakan teknik total sampling yang memenuhi kriteria inklusi dan eksklusi berupa pasien memiliki komorbid lebih dari 1 dan data rekam medis pasien yang tidak lengkap. Data yang diambil pada rekam medis pasien COVID-19 di Rumah Sakit Universitas Andalas berupa usia, jenis kelamin, gejala klinis, dan tingkat keparahan; Hasil: Sebanyak 179 data rekam medis pasien dengan diagnosis COVID-19 diperoleh pada penelitian ini, karakteristik terbanyak usia 56-65 tahun dengan mayoritas jenis kelamin perempuan, gejala klinis terbanyak batuk, dan tingkat keparahan terbanyak sedang dan berat; Kesimpulan: Berdasarkan hasil penelitian dapat disimpulkan bahwa terdapat perbedaan yang bermakna pada karakteristik usia, gejala klinis, dan tingkat keparahan pada pasien COVID-19 dengan komorbid DM tipe 2 dan non-DM tipe 2 di Rumah Sakit Universitas Andalas. 
Co-Authors Abdiana Addina, Azka Adrial Adrial Afdal Afdal Afriwardi Afriwardi Ahmad, Armen Akmal M. Hanif Alexander Kam Alexander Kam Alifah Amirah Alifya Rafifah Tarwandi Almurdi Almurdi Amirah Zatil Izzah Andani E. Putra Andani Eka Putra Anggia Perdana Harmen Anum, Qaira Aprilia, Dinda Arina Widya Murni Arina Widya Murni Arnelis . Azia Putri Al Jamil Bestari J. Budiman Citra Manela Claudia Triananda Deddy Saputra Deka Viotra Deka Viotra Delfin, Muhamad Dessy Arisanty Dia Rofinda, Zelly Dia Dian Pertiwi Dian Pertiwi Dinda Aprilia Djong Hon Tjong Drajad Priyono Efrida Efrida Eka Kurniawan Elfi Fauzana Akmal Elfira Yusri Elvia Fataya Eva Decroli Fadhla, Azizah Fadrian, Fadrian Faheri, Eifel Fanny Adhy Putri Fauzar Fauzar Firdawati Firdawati Fortuna, Fory Gardenia Akhyar Gestina Aliska Gestina Aliska Gustia Anugrahwati Gustin, Hanna Harun Harnavi Hasmiwati Hendriati, Hendriati Herinda, Dwi Putri Herman, Deddy Husni Husni Ilmiawati, Ilmiawati Jannah, Lidya Raudhatul Julizar Julizar Julizar Kurniawan, Eka Linosefa Linosefa Malinda Meinapuri masri, Raveinal Muhamad Delfin Muhammad Iqbal Andreas Muhammad Rafif Sulthan Habibi Mustafa Noer Mustafa Noer Nadia, Rizka Najirman Najirman Netti Suharti Netti Suharti, Netti Noverika Windasari Nurvalinda Nurvalinda Paishal Mizan Poedjijo, Yanuar Saputra Poedjijo, Yanuar Surya Saputra Puji Oktavia Puti Anggun Sari Rahayuningsih, Sri Puji Rahmadina, Rahmadina Rahmadina, Rahmadina Rahmatini . Raveinal Raveinal Raveinal Raveinal RAVEINAL RAVEINAL Raveinal Raveinal Raveinal Raveinal Rido Wandrivel Rijalun Arridho Rikarni Rikarni Rina Gustia Rini Gusya Liza, Rini Gusya Rismawati Yaswir Rizka Nadia Rizqy Auliya Lubis Rose Dinda Martini Roza Kurniati Roza Kurniati Roza Kurniati Roza Mulyana Roza Mulyana RR. Ella Evrita Hestiandari Rudy Afriant Russilawati, Russilawati Saptino Miro Saptino Miro, Saptino Saputra Poedjijo, Yanuar Surya Selfi Renita Rusjdi Selfi Renita Rusjdi Shinta Ayu Intan Siti Nurhajjah Steven, Rios Suci Maulida Syandrez Prima Putra Syandrez Prima Putra Tazkia Aulia Permata Helena Ulti, Zifa Amanda Vesri Yoga WAHYUDI Wahyudi . Yenita Yenita Yuliarni Syafrita Yulistini, Yulistini Yusticia Katar zahra salsabila Zaky Athila Naufal Zelly Dia Rofinda Zilhadia Zulfiqar, Yevri Zurayya Fadila