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All Journal EJIP BIOL Biocelebes INDONESIAN JOURNAL OF PHARMACY JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Dinamika Pengabdian (JDP) Science and Technology Indonesia Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Health Notions Indonesian Journal on Software Engineering (IJSE) Jurnal Pilar Nusa Mandiri Jurnal Pembelajaran Matematika Jurnal Biologi Tropis JITK (Jurnal Ilmu Pengetahuan dan Komputer) Indonesian Journal of Chemistry JMM (Jurnal Masyarakat Mandiri) JIKG (Jurnal Ilmu Kedokteran Gigi) JSFK (Jurnal Sains Farmasi & Klinis) JURNAL TEKNOLOGI DAN OPEN SOURCE Jurnal Kreativitas PKM JCRS (Journal of Community Research and Service) Journal of Information System, Applied, Management, Accounting and Research JATI (Jurnal Mahasiswa Teknik Informatika) Jurnal Abdi: Media Pengabdian Kepada Masyarakat Jurnal Tekinkom (Teknik Informasi dan Komputer) Indonesian Journal for Social Responsibility Jurnal Infortech Jurnal Layanan Masyarakat (Journal of Public Service) Abditeknika - Jurnal Pengabdian Kepada Masyarakat Reputasi: Jurnal Rekayasa Perangkat Lunak Jurnal Pengabdian Masyarakat Hasanuddin (JPMH) Tri Dharma Mandiri: Diseminasi dan Hilirisasi Riset Kepada Masyarakat (Jurnal Pengabdian Kepada Masyarakat) Journal of Health and Nutrition Research JAMAS: Jurnal Abdi Masyarakat Journal of Accounting Information System Promotor: Jurnal Mahasiswa Kesehatan Masyarakat Jurnal Pengabdian Kepada Masyarakat SCIENTIA JOURNAL : Jurnal Ilmiah Mahasiswa
Retno Sari
Department Of Pharmaceutics, Faculty Of Pharmacy, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Green Synthesis of Antimicrobial Silver Nanoparticles using Green Tea Extract: The Role of Concentration and pH Hasan, Wafiqah Latuapo; Sari, Retno; Hendradi, Esti
JSFK (Jurnal Sains Farmasi & Klinis) Vol 11 No 1 (2024): J Sains Farm Klin 11(1), April 2024
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.11.1.25-31.2024

Abstract

Silver nanoparticles (AgNP) have been proven effective against many microbial strains with their superior antibacterial  properties, due to their nano size and large surface area that can interact directly with the bacterial structure. Green synthesis  for silver nanoparticles is the process of reducing Ag+ ions to Ag0 using plant bioactive compounds. Green synthesis is safer,  environmentally friendly, and cost-effective. Camellia sinensis L. (green tea) containing polyphenols that can be used as a  bioreductant in the formation of silver nanoparticles. This study aims to determine the effect of various concentration of AgNO3,  green tea extract, and pH on the physical characteristics and antibacterial activity of silver nanoparticles. The AgNPs were  evaluated by UV-Vis Spectrophotometer, Dynamic Light Scattering (DLS), Scanning Electron Microscopy (SEM), and Fourier transform infrared spectroscopy (FTIR). The result demonstrated that the optimal AgNP was obtained from the AgNO3 concentration of 1.5 mM with 0.003% green tea extract at pH 10 which showed the highest absorbance value of 4.420 at λ  435.3 nm, with a particle size of 47.1 nm and a PDI of 0.243. The AgNPs showed growth inhibition on Staphylococcus aureus and  Escherichia coli and the antibacterial activity enhance compare to AgNO3.
Peningkatan Nilai Guna Limbah Kulit Jeruk Nipis melalui Produk Sederhana Guna Mendukung SDGs bagi Petani Jeruk di Kecamatan Ujung Pangkah, Gresik Sari, Retno; Hendradi, Esti; Rijal, Agus Syamsur; Retnowati, Dini; Suzana, Suzana; Ramadhani, Firmansyah Ardian; Miatmoko, Andang; Sulistyowati, Melanny Ika; Sukardiman, Sukardiman; Ekowati, Juni
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 1 (2025): Volume 8 No 1 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i1.18244

Abstract

ABSTRAK Permasalahan di Desa Bolo Ujung Pangkah Gresik produksi jeruk nipis yang tinggi/melimpah. Sehingga harga jual menjadi rendah dan banyak produk panen tidak dapat terserap oleh pasar. Selain itu limbah kulit jeruk nipis yang terbuang juga akan meningkat. Hal ini akan mengakibatkan kerugian bagi petani. Permasalahan tersebut akan dibantu dengan kegiatan pengabdian kepada masyarakat dengan tujuan untuk menambah pengetahuan masyarakat dengan meningkatkan nilai guna limbah jeruk nipis di kecamatan Ujung Pangkah, Gresik, khususnya di desa Bolo melalui pengolahan produk berbahan ekstrak kulit jeruk nipis. Hal ini sesuai dengan tujuan Sustainable Development Goals (SDGs) 12 yaitu pemanfaatan sumber daya alam yang efisien. Kegiatan pengabdian masyarakat diawali dengan pre-test yang dilanjutkan dengan pemaparan materi dan demo pembuatan produk micellar water dan hand sanitizer dari ekstrak kulit jeruk. Selanjutnya dilakukan post-test untuk mengukur perubahan pengetahuan peserta setelah pelatihan. Berdasarkan hasil pre-test dan post-test terdapat peningkatan kemampuan dan pengetahuan peserta tentang khasiat bahan yang terkandung dari kulit jeruk. Peserta dapat meningkatkan nilai guna dari limbah kulit jeruk nipis dalam bentuk produk sederhana kaya manfaat seperti micellar water dan hand sanitizer dari kulit jeruk nipis. Kata Kunci: Kulit Jeruk Nipis, Micellar Water, Hand Sanitizer, SDGs 12  ABSTRACT The problem in Bolo Ujung Pangkah Gresik Village is the high/abundant production of limes. So that the selling price is low and many harvested products cannot be absorbed by the market. In addition, the waste of lime peels that are thrown away will also increase. This will result in losses for farmers. The problem will be helped by community service activities with the aim of increasing public knowledge by increasing the utility value of lime waste in Ujung Pangkah sub-district, Gresik, especially in Bolo village through processing products made from lime peel extract. This is in accordance with the objectives of Sustainable Development Goals (SDGs) 12, namely efficient utilization of natural resources. Community service activities began with a pre-test followed by a presentation of materials and a demonstration of making micellar water and hand sanitizer products from orange peel extract. A post-test was then conducted to measure changes in participants' knowledge after the training. Based on the results of the pre-test and post-test, there was an increase in participants' abilities and knowledge about the properties of the ingredients contained in lime peel. Participants can increase the utility value of lime peel waste in the form of simple, beneficial products such as micellar water and hand sanitizer from lime peel. Keywords: Lime Peel, Micellar Water, Hand Sanitizer, SDGs 12
PELATIHAN DISPENSING ASEPTIK SEDIAAN STERIL DI LAYANAN KESEHATAN KOTA MAKASSAR CITY DAN SEKITARNYA: Training on Aseptic Dispensing of Sterile Preparations in The Health Services of Makassar and Surroundings Isadiartuti, Dewi; Sari, Retno; Rijal, Muh. Agus Syamsur; Ratri, Dinda Monika Nusantara; Retnowati, Dini; Rudyanto, Marcellino; Miatmoko, Andang
JAMAS : Jurnal Abdi Masyarakat Vol. 3 No. 1 (2025)
Publisher : Forind Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62085/jms.v3i1.172

Abstract

Sediaan steril adalah sediaan yang tidak boleh mengandung mikroorganisme, partikel, serta sedapat mungkin dibuat isotonis. Kondisi steril tersebut harus dapat dijamin oleh apoteker sampai sediaan digunakan oleh pasien. Salah satu jenis pelayanan kefarmasian yang dilakukan oleh apoteker di fasilitas kesehatan adalah disepensing sediaan steril. Proses dispensing sediaan steril memerlukan teknik aseptis. Teknik aseptis merupakan salah satu aspek penting yang perlu diperhatikan oleh apoteker dalam menjalankan praktik kefarmasian khususnya di rumah sakit. Makassar yang merupakan ibukota Provinsi Sulawesi Selatan merupakan kota keempat terbesar di Indonesia. Kota Makassar merupakan tempat tinggal bagi lebih dari 15% penduduk Provinsi Sulawesi Selatan. Jumlah penduduk yang terus meningkat dan kualitas sumber daya yang baik sangat berguna untuk mendorong pertumbuhan ekonomi. Namun, jika tidak didukung dengan sumber daya manusia yang berkualitas, masalah sosial di Kota Makassar akan semakin meningkat. Salah satu cara dalam meningkatkan sumber daya manusia dapat melalui pengabdian masyarakat. Tujuan dari pengabdian masyarakat adalah untuk meningkatkan pengetahuan serta ketrampilan apoteker dalam hal dispensing aseptik sediaan steril di layanan kesehatan Kota Makassar dan sekitarnya. Kegiatan dilaksanakan di Auditorium Universitas Islam Makassar pada hari Sabtu 19 Oktober 2024 diikuti 34 peserta apoteker dari Rumah Sakit dan Puskesmas yang melakukan layanan pengelolaan sediaan steril. Dari hasil pre/post test tentang materi yang diberikan dan evaluasi kegiatan menunjukkan peningkatan pemahaman peserta dan respon positif terhadap pelatihan yang diselenggarakan oleh tim pengabdian masyarakat Fakultas Farmasi Universitas Airlangga. Harapan peserta pelatihan di masa mendatang kegiatan diperbanyak dan alokasi waktu pelaksanaan dapat lebih diperpanjang.
PENGARUH KUALITAS PELAYANAN DAN KEPERCAYAAN TERHADAP KEPUASAN PASIEN HEALTH CARE BATAM Sari, Retno; Syaifullah, Syaifullah
SCIENTIA JOURNAL Vol 1 No 2 (2019): Volume 1 No 2 2019
Publisher : LPPM Universitas Putera Batam

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

In this study entitled The Influence of Service Quality and Trust in Satisfaction of Batam Health Care Patients, The purpose of this study was to determine the quality of services implemented by the Tamrin Health Care and Trust Clinic of patients towards the Tamrin Health Care Clinic that was used was using quantitative methods and using questionnaires. Are there any effects of service quality on patient trust and satisfaction. The sampling method in this study is to use probability sampling method, which is a sample lighting technique that provides equal opportunities for each member of the population to be selected as a sample. Thus Service Quality (X1) and Trust (X2) have a positive effect on Patient Satisfaction (Y) at Tamrin Health Care Clinic. That is Service Quality variable (X1) proves with significant value (0,000) <alpha value (0,05) and value so that t count> t table 5,919> 1,9717, Trust variable (X2) is significant (0,006) <alpha value (0,05) ) and value so that t count> t table 2,785> 1,9717, variable Patient Satisfaction (Y) is significant (0,000) <alpha value (0,05) and fcount> f table (32,886> 3,04).
Deteksi Bahan Tambahan Makanan dan Obat melalui Pendekatan Nanosensor di BPOM Surabaya Amalina, Ilma; Hayaza, Suhailah; Jiwanti, Prastika Krisma; Saputra, Mirza Ardella; Susilo, Raden Joko Kuncoroningrat; Amrillah, Tahta; Firmansyah, Mochammad Lutfi; Mulya, Fadjar; Sari, Retno
Jurnal Pengabdian Masyarakat Hasanuddin (JPMH) Vol 6 No 1 (2025)
Publisher : Universitas Hasanuddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31947/jpmh.v6i1.44257

Abstract

Perkembangan nanoteknologi dalam bidang kesehatan memiliki manfaat yang sangat besar, seperti ditemukaannya material penghantaran obat yang efektif, termasuk juga dalam aplikasi deteksi dini berbagai penyakit, cemaran berbahaya dalam tubuh, maupun lingkungan. Selain itu, dalam upaya pengawasan makanan, nanoteknologi berperan dalam terciptanya alat pendeteksi dini bahan tambahan makanan, yang diketahui berbahaya apabila dikonsumsi oleh manusia secara berlebih, seperti adanya zat warna yang tidak diijinkan maupun kandungan tambahan makanan yang melebihi batas toleransi. Nanosensor berbasis screen printed electrode (SPE) merupakan salah satu teknologi yang dapat digunakan untuk mewujudkan terciptanya rangkaian alat pendeteksi yang cepat, sensitif, dan portable. Pada kegiatan ini, nanoteknologi yang diterapkan pada pembuatan alat nanosensor diperkenalkan khususnya kepada analis yang ada di pusat pengawasan obat dan makanan serta dinas kesehatan, sehingga dapat meningkatkan pengetahuan tim badan pengawas obat dan makanan tentang manfaat nanoteknologi dalam pendeteksian bahan tambahan makanan. Kegiatan ini juga merupakan upaya untuk menjalin kerjasama berkelanjutan antara tim pengabdian masyarakat yang merupakan peneliti dalam bidang nanosensor dengan user di lapangan yang merupakan badan pengawas obat dan makanan, untuk mengembangkan teknologi nanosensor sesuai dengan kebutuhan di lapangan. Kegiatan ini dilaksanakan di Badan Pengawas Obat dan Makanan Surabaya, Jawa Timur. Acara dihadiri oleh 57 apoteker dan analis di lingkungan pusat pengawasan obat dan makanan, dinas kesehatan, serta instansi swasta di Surabaya. Kegiatan ini diisi dengan edukasi tentang aplikasi nanoteknologi diberbagai bidang serta demo penggunaan alat nanosensor berbasis SPE untuk mendeteksi logam berat, antibiotic, dan pewarna makanan. Sebanyak lebih dari 57% peserta menyatakaan sangat puas dengan pelaksanaan kegiatan ini. Dari kegiatan pengabdian masyarakat yang dilakukan dihasilkan artikel ilmiah dan publikasi pada media cetak/elektronik, serta video rangkaian kegiatan pengabdian masyarakat, sesuai dengan indikator kinerja utama yang ditetapkan secara nasional.
Pelatihan AI untuk Optimalisasi Kegiatan Yayasan IRMA Menuju Era Transformasi Digital Hidayat, Taopik; Seimahuira, Syarah; Saryoko, Andi; Sari, Retno; Eka Saputra, Bagas; Muzakki Ramadhan, Naufal; Budi Santoso, Satrio
Jurnal Pengabdian kepada Masyarakat Vol. 12 No. 1 (2025): JURNAL PENGABDIAN KEPADA MASYARAKAT 2025
Publisher : P3M Politeknik Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33795/abdimas.v12i1.6462

Abstract

The rapid advancement of Artificial Intelligence (AI) technology is significantly influencing various sectors, including government and industry, by simplifying tasks traditionally performed by humans and creating new opportunities. The objective of this community service initiative was to enhance the technological skills of the caretakers at the Yayasan Santunan Yatim Piatu dan Sosial IRMA in South Jakarta, enabling them to utilize AI for daily activities and organizational needs. This program employed a three-step approach: preparation, implementation, and evaluation. In the preparation phase, challenges faced by the organization in adopting AI were identified, and necessary permissions were secured. The implementation phase involved interactive workshops focusing on computer usage and AI applications, fostering participant engagement through discussions and hands-on activities. Monitoring and evaluation were conducted using questionnaires to assess participant understanding and gather feedback on the training's effectiveness. Results indicated a marked improvement in participants' AI skills, enhancing their organizational capabilities and contributing positively to community development.
ANALISIS SENTIMEN MASYARAKAT INDONESIA TERHADAP PELUNCURAN DANANTARA MENGGUNAKAN METODE SUPPORT VECTOR MACHINE Sari, Retno; Agustin, Agustin; Rahmiati, Rahmiati; Junadhi, Junadhi
Jurnal Teknik Informasi dan Komputer (Tekinkom) Vol 8 No 1 (2025)
Publisher : Politeknik Bisnis Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37600/tekinkom.v8i1.2351

Abstract

As one of the latest innovations in Indonesia, the launch of Danantara has attracted public attention, especially the X (formerly Twitter) social media community. Understanding public sentiment about the launch is crucial due to the varied reactions. Using the Support Vector Machine (SVM) method as the primary classification algorithm, this study aims to examine how Indonesians perceive the launch of Danantara. Data collected through scraping techniques from social media posts were then processed through text preprocessing processes such as data cleaning, tokenization, and normalization. Categorizing sentiment into positive, negative, or neutral can be done using the signal variable model (SVM). The results show that the majority of the public has a certain sentiment towards the launch of Danantara, as the SVM model can classify sentiment very accurately. In the future, this study will help stakeholders understand public opinion and create better communication plans.
PERAN STRATEGIS PKK DALAM MENUNJANG PENINGKATKAN PEMAHAMAN MASYARAKAT TENTANG OBAT DAN SUPLEMEN MAKANAN Hendradi, Esti; Sari, Retno; Purwanti, Tutiek; Erawati, Tristiana; Miatmoko, Andang; Sugiyartono, Sugiyartono
JMM (Jurnal Masyarakat Mandiri) Vol 9, No 2 (2025): April
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v9i2.28739

Abstract

Abstrak: Pemahaman masyarakat tentang obat termasuk cara mendapatkan, menggunakan, menyimpan dan membuang serta penggunaan suplemen makanan masih perlu mendapat perhatian khusus, terutama untuk masyarakat perifer. Peran apoteker dibutuhkan dalam mengedukasi masyarakat dengan melibatkan gerakan Pemberdayaan dan Kesejahteraan Keluarga (PKK). Tujuan PKM ini adalah meningkatkan pengetahuan tentang obat dan suplemen makanan kepada masyarakat dengan memberdayakan PKK. Tim pengabdian kepada masyarakat Fakultas Farmasi Universitas Airlangga telah menyelenggarakan kegiatan bakti sosial bersama-sama IAI dan kader PKK di Kota Madya Tuban dalam bentuk penyuluhan atau sosialisasi terkait obat dan suplemen makanan. Sosialisasi dilakukan melalui Webinar via Zoom Meeting dalam bentuk seminar dan diskusi interaktif, karena aktivitas pengabdian dilaksanakan saat pandemi Covid-19. Sebagai mitra pada pengabdian masyarakat ini adalah Kader PKK dan Ketua Ikatan Apoteker Indonesia (IAI) Cabang Tuban dengan jumlah peserta yang hadir sejumlah 71 orang. Hasil evaluasi melalui pre-test dan post-test menunjukkan bahwa setelah mengikuti kegiatan rerata pemahaman peserta meningkat 7,04% dan 12,7% masing-masing untuk materi DAGUSIBU dan Probiotik. Diharapkan PKK secara aktif menyebar-luaskan kegiatan sosialisasi kepada masyarakat di seluruh desa.Abstract: Public understanding of medicines, including how to obtain, use, store and dispose of them as well as the use of food supplements, still needs special attention, especially for peripheral communities. The role of pharmacists is needed in educating the public by involving the Family Empowerment and Welfare (PKK) movement. The aim of this PKM is to increase knowledge about medicines and food supplements among the community by empowering PKK. The community service team at the Faculty of Pharmacy, Airlangga University has held social service activities together with IAI and PKK cadres in Tuban in the form of counseling or outreach regarding medicines and food supplements. Socialization was carried out through Webinar via Zoom Meeting in the form of seminars and interactive discussions, because service activities were carried out during the Covid-19 pandemic. As partners in this community service were PKK cadres and the Chair of the Indonesian Pharmacists Association (IAI) in Tuban city with a total of 71 participants attending. The evaluation results via pre-test and post-test showed that after participating in the activity the participants' average understanding increased by 7.04% and 12.7% for DAGUSIBU and Probiotic material, respectively. It is hoped that the PKK will actively spread outreach activities to communities throughout the village.
Implementation of Marketing Mix Strategy at Soelastri Dental and Oral Hospital Sari, Retno; Theo, Deli; Nasution, Ramadhani Syafitri
PROMOTOR Vol. 8 No. 4 (2025): AGUSTUS
Publisher : Universitas Ibn Khaldun Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/pro.v8i4.1419

Abstract

Dental and oral health has an effect on improving the quality of life and productivity of human resources. RSGM Soelastri is one of the dental and oral health service facilities. The condition of visits of inpatients and new emergency room patients in 2024 has fluctuated and is below the target. This can result in a decrease in hospital revenue and can have an impact on the disruption of hospital operational activities, so that the services provided to patients are not optimal. Therefore, it is necessary to conduct a review of the marketing strategy of RSGM Soelastri. The purpose of this study is to analyze the implementation of marketing strategies at Soelastri Dental and Oral Hospital. This research uses a qualitative method, through in-depth interview techniques. Data sources are obtained from primary data and secondary data. There were 14 informants, divided into 8 main informants and 6 supporting informants. Data analysis by checking the results of the research with different data collection techniques, namely interviews, observations, and documentation. The results of the study are known that RSGM Soelastri has carried out segmentation, targeting and market positioning. RSGM Soelastri has carried out promotional activities such as counseling, but it has not been maximized. Promotion has not reached all levels of society. The types of services offered are complete. Service rates are able to compete with other hospitals. RSGM Soelastri includes staff in various types of training, but it is still limited. The tools used are modern, but there are some computer devices and radiology printers that are no longer efficient for service. There are limited human resources and financial constraints. The conclusion of this study is that the implementation of marketing strategies consisting of market segmentation, target market, positioning, and market surveys has been carried out, but not optimally. The implementation of the 7P Marketing Mix at RSGM Soelastri has been carried out, but it has not been maximized. The implementation of marketing strategies is constrained by budgets and human resources. It is suggested for other researchers, it is necessary to conduct research on marketing strategies in more depth by looking at the promotion mix of inpatient and emergency room services as one of the services that support the number of patient visits at RSGM Soelastri.
The Anticancer Activity of Ethanol Extract of Begonia medicinalis on Colorectal Cancer Rat Model Induced With 7,12-Dimethylbenz[A]Anthracene Guli, Musjaya; Ardiputra, Muh Akbar; Pitopang, Ramadanil; Sari, Retno; Hatta, Mochammad; Prawiro, Sumarno Reto; Saifah, Andi; Sardi, Bambang; Rahma, Rahma; Rahmawati, Nurul Dina
Journal of Health and Nutrition Research Vol. 4 No. 2 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i2.411

Abstract

Colorectal cancer remains one of the leading causes of cancer-related deaths after lung cancer, highlighting the urgent need for more effective therapies with minimal side effects. Begonia medicinalis has been reported to have potential anticancer properties. This study aimed to evaluate the anticancer activity of Begonia medicinalis extract by assessing neutrophil concentration in a 7,12-dimethylbenz[a]anthracene (DMBA)-induced colorectal cancer rat model. The research employed a laboratory-based experimental approach with a post-test-only group design, comprising five groups with five replications each: treatment group I receiving a 25 mg/kg body weight, treatment group II receiving a 50 mg/kg body weight, treatment group III receiving a 100 mg/kg body weight, an normal group that was not DMBA-induced and did not receive therapy, and a negative control group that was DMBA-induced but did not receive therapy. The results of this study demonstrate that Begonia medicinalis extract effectively suppresses neutrophil concentration in a DMBA-induced colorectal cancer rat model. Treatment with 50 mg/kg body weight and 100 mg/kg body weight doses successfully reduced neutrophil cell levels in the experimental subjects, with the best results seen at the 100 mg/kg body weight dosage. This study provides new insights into the effects of plant-based therapies, Begonia medicinalis extract, in modulating the immune system by suppressing neutrophil concentration in a colorectal cancer rat model.
Co-Authors , Idha Kusumawati Abd Hakim Laenggeng, Abd Hakim Abhimata Paramanandana Adhitiawarman, Adhitiawarman Adjat Sudradjat Agus Syamsur Rijal, Muh. Agustin Agustin Alam, Gust Rizki Samudra Noor Andang Miatmoko Andi Saifah Andi Saryoko Andre Andre, Andre Anggai, Rifka Anggraini Annisa Maulidia Rahayyu Ardiputra, Muh Akbar Arief Cahyo Wibowo Asri Pirade Paserang Bambang Sardi Bastoni Semendawai Budi Santoso, Satrio Dewanthy, Kyrana Sekar Dewi Isadiartuti Dewi Isadiartuti Dhurriah Zain Dicky Kurniawan, Muhammad Dinda Monika Nusantara Ratri Dini Retnowati Dini Retnowati Diyah, Nuzul Wahyuning dwi hartanto Dwi Mulyana, Septian Dwi Setyawan Eka Saputra, Bagas Eryka A. Novarinandha Esti Hendradi Fadjar Mulya Fauzia, Alfi Nur Febrianti, Clara Firmansyah, Mochamad Lutfi Firmansyah, Mochammad Lutfi Fitrallisan Fitrallisan Guli, Musjaya Hardini, Erza Shafiah Zahraani Pravita Hasan, Wafiqah Latuapo Hidayad, Khavid Ida Ayu Putu Sri Widnyani Idha Kusumawati Ilma Amalina Imam Sujadi Intan Nurul Rizki Iqbal, Moh Irma Purnamasari, Ade Junadhi, Junadhi Juni Ekowati Kresna Ramanda Laksono Trisnantoro Lemako, Gideon Sulivan Lumbantoruan, Daniel M. Agus Syamsur Rijal M. Agus Syamsur Rijal Marcellino Rudyanto Maria Lucia Ardhani Dwi Lestari Marlina Marlina Miatmoko, Andang Mirza Ardella Saputra Mochammad Hatta Muchammad Farchan Chanif Muchammad Farchan Hanif Mufariha, Mufariha Muh Agus S Rijal Muhammad Aditya Bryan Rahadi Muhammad Agus Syamsur Rijal Muhammad Fahrizal Himawan Muhammad Ilyas Mulya, Fadjar Mulyana, Septian Dwi Mustafid Rasyiid Muzakki Ramadhan, Naufal Nasution, Ramadhani Syafitri Noorma Rosita Nugroho, Dito Pradita Nur Rahmiati, Nur Patigu, Rosy Feraningsih Pawahid Pawahid Pohwain, Berkhat Agung Prastika Krisma Jiwanti Prawiro, Sumarno Reto Raden Joko Kuncoroningrat Susilo Rahayyu, Annisa Maulidia Rahma Rahma Rahmawati, Nurul Dina Rahmiati Rahmiati Ramadanil Pitopang Ramadhan, Wahyu Satria Ramadhani, Firmansyah Ardian Rani Naomi Panjaitan Ratih Yulia Hayuningtyas Ridwansyah Ridwansyah Rifka Anggraini Anggai Rijal, Agus Syamsur Rijal, M. Agus Syamsur Rinaldi Dikanda, Arif Rohana, Melissa Rosyda, Susy Sartini Sartini Seimahuira, Syarah Septian Nafiatul Khasanah Siammita, Dhea Anansya Siti Nurhasanah Nugraha Sugiyartono Sugiyartono Sugiyartono, Sugiyartono Suhailah Hayaza Sukardiman Sulistyowati, Melanny Ika sultan, firdaus SUZANA, SUZANA Tahta Amrillah Taopik Hidayat Theo, Deli Tri Atmojo Kusmayadi Tristiana Erawati Tutiek Purwanti Tutik Sri Wahyuni Wahyu Harso Widji Soeratri Yeremia Budi Cristian