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All Journal Jurnal Anestesiologi Indonesia JBIO: jurnal biosains (the journal of biosciences) Public Health of Indonesia Molecular and Cellular Biomedical Sciences (MCBS) Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Journal of Epidemiology and Public Health Indonesian Journal of Medicine Journal of Maternal and Child Health Callosum Neurology Journal : Jurnal Berkala Neurologi Bali Jurnal Respirologi Indonesia Oto Rhino Laryngologica Indonesiana Jurnal Respirasi (JR) Sumatera Medical Journal Medika Kartika : Jurnal Kedokteran dan Kesehatan Jurnal Prima Medika Sains Respiratory Science Jurnal Impresi Indonesia Prosiding Konferensi Nasional PKM-CSR Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara The Journal of Society Medicine (JSOCMED) MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Cermin Dunia Kedokteran Deli Medical and Health Science Journal
Putri Chairani Eyanoer, Putri Chairani
Department Of Publich Health Faculty Of Medicine, Universitas Sumatera Utara
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Journal : Jurnal Anestesiologi Indonesia

 1 
Comparison of The Effectiveness Between Fentanyl and Ketamine as Adjuvant Epidural Analgesia with Ropivacaine In Post Operation of The Lower Extremity Pratama, Mhd. Rizki; Ihsan, Mhd.; Hamdi, Tasrif; Eyanoer, Putri Chairani
JAI (Jurnal Anestesiologi Indonesia) Vol 17, No 1 (2025): JAI (Jurnal Anestesiologi Indonesia)
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.64228

Abstract

Background: One typical side effect that frequently follows surgery is pain. Lower limb surgery procedures can cause tissue and nerve damage. When compared to systemic opioids, epidural analgesia provides better postoperative analgesia. Adjuvants extend and intensify sensory blockage, which increases the effectiveness of local anesthesia. They also cause the dose of local anesthetic drugs to be reduced.Objective: To determine the comparative effectiveness of adjuvant fentanyl compared with ketamine and ropivacaine as adjuvant epidural analgesia in post-lower extremity surgery patients.Methods: The purpose of this randomized controlled experiment is to compare the efficacy of ketamine and fentanyl as adjuvant epidural analgesia in postoperative lower extremities when combined with ropivacaine. In this study, two groups of patients were given epidural anesthesia: the first group received ropivacaine 0.25% with 125 mcg of fentanyl adjuvant, while the second group received ropivacaine with 0.25% with ketamine 10 mg. The double-blind technique was used to select a total sample of 29 individuals from each group based on inclusion and exclusion criteria. The assessment of pain scores, hemodynamics, treatment-related side effects, and bromage scores was used to test both groups.Result: The T5 assessment showed a substantial difference in the pain scores at rest. With a total of 14 side effects, blood pressure and pulse rate fluctuations were the most common, accounting for 20% of the side effects. Despite this, patients in the ropivacaine + ketamine adjuvant group continued to experience hemodynamic stability and comfort. There were two side effects in the fentanyl combination group, with nausea being the most common. Between the therapy groups, there was no difference in the recovery of the bromage score (p>0.05).Conclusion: Ropivacaine-ketamine has favorable effectiveness as an analgesia adjuvant compared to ropivacaine-fentanyl.
Co-Authors -, Fadhlia Ade Rahmaini Adlin Adnan Alona, Ivana Alwi Thamrin Nasution Amaiappan, Jesvinder Andika Pradana Andika Pradana Andika Pradana Arieta, Lydia Arlinda Sari Wahyuni Armon Rahimi Asnir, Rizalina Arwinati Azali, Chairul Nurdin Azizah Ghanie Icksan Bintang Yinke Magdalena Sinaga Bintang Yinke Magdalena Sinaga Bintang YM Sinaga Bintang YM Sinaga Budi Jefri Budi Wiweko Chairiza Muttaqien Dana Jauhara Layali Delfitri Munir Delfitri Munir Delores Elisabeth Sormin Destylya, Dyana Dyana Destylya Eddy Bangun Elisabeth Elisabeth Elizabeth Napitupulu Elmeida Effendy Elok Ariyani Safitri Elva Susanty Elvita Rahmi Daulay Endy Juli Anto Endy Todo Sirait endyjulianto endyjulianto Eva Susanti Debora Hutabarat Evo Elidar Harahap Fachrezi, Muhammad Alfian FAHDI, FIRDAUS Fajrinur Syahrani Fajrinur Syahrani Fajrinur Syaran Fajrinur Syarani Fajrinur Syarani Fajrinur Syarani Faradila, Devita Farhat, Farhat Faried, Mukhamad Febiyanti, Mica Felisia Felisia Firdaus, Ruby Fransisco Sentosa Pakpahan Fujiati, Isti Ilmiati Ganda M. Leonard Samosir Ghazali Akhmad Putranta Ginting, Franciscus Hadi Suhendra Hafizhalaila Ammar Hakim, Enggrek Pelita Hamdi, Tasrif Harahap, Juliandi Haryuna, Tengku Siti Hajar Hasibuan, Mangain Hemma Yulfi Hendri Wijaya, Hendri Henny Maisara Sipahutar Herani Mutia Riandini Hidayat Hidayat Ihsan, Mhd. Joshua Asley Juli Anto, Endy Juliandi Harahap Kadri, Alfansuri Kartini harahap Kembaren, Tambar kenvin rusli Kiking Ritarwan Listyoko, Aditya Sri Lubis, Muhammad Allif Syafrin Lubis, Netty Delvrita Maesyara Adinda Sari Maulidina Hsb, Putri Sari Muhammad Ichwan Muhammad Zainul A Muntasir Abdullah Nababan, Windika Nasution, Duma Ratna Sari Netty Delvrita Lubis Netty Delvrita Lubis Noni Novisari Soeroso Noni Novisari Soeroso Noni Novisari Soeroso Nurdiansah, Firman Nurul Citta Banu Putri Nurul Ramadhani Nuryunita Nainggolan Octavia, Nur Afni Heryanti Pandia, Pandiaman Pandiaman Pandia Pandiaman Pandia Panjaitan, Alfred Johnatan Pardede, Sujahn Anto Parluhutan Siagian Parluhutan Siagian Parluhutan Siagian Pase, M Aron Pendiaman Pandia Perangin-angin, Gwanita Nawariantina Peter Peter Pratama, Mhd. Rizki Pratiwi, Ade Dwi R.A Henny Anggriani Ramadhani, Adini Arifah Rambe, Andrina Yunita Murni Restuti Hidayani Saragih Ribawanto, Muhammad Rafif Rifda Hayati Rina Amelia Rina Yunita Ririe Fachrina Malisie Risqin, Muhammad Anas Fatah Rosita Juwita Sembiring Salsabila, Anisa Samodra, Yoseph Leonardo Sarah, Dewi Maya Sekali, Oktaviani Karo Selvy Wulandari Siahaan, Jekson Martiar Sikumbang, Rahmat Hidayat Sinaga, Bintang Yinke Magdalena Sinaga, Joshua Princeman Sinaga, Sudirman Parningotan Sirait, Asima Rodiarta Siregar, Nondang Purnama Syamsul Bihar Syamsul Bihar Syamsul Bihar Syarani, Fajrinur Tarigan, Amira Permatasari Tarigan, Setia Putra Tri Setia Negara Sinulingga Vera, Yeni Wahyuni, Arlinda Sari Wan Betty Pratiwi Yahwardiah Siregar Yessi Andriani Zainal Yunanda, Yuki Zainuddin Amir Zakirah, Sarah Chairani