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Journal : Respiratory Science

The Effect of Two-Mile Jogging Training on Lung Function Values in TNI Soldier Kodam I/Bukit Barisan Rifda Hayati; Nuryunita Nainggolan; Amira Permatasari Tarigan; Putri Chairani Eyanoer
Respiratory Science Vol. 1 No. 1 (2020): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v1i1.8

Abstract

Background: Military soldiers are army personnel who are required to have good physical endurance and optimal fitness, include. So, it's needed physical exercise, include to be able to improve lung function. One parameter that can reflect physical fitness are lung function and m VO2max. This study aims to determine whether there is a relationship between physical exercise in the form of 2-mile jogging with increased lung function and VO2max of military soldiers Kodam 1 Bukit Barisan Methods: This research is an experimental study carried out in February-April 2019 against the TNI soldiers of the Bukit Barisan Military District 1. The research subjects were divided into two groups, group 1 who underwent regular 2-mile jogging exercises 3-5 times a week with a duration of 25 minutes for 2 months, and group 2 who underwent non-routine jogging exercises (less than 3 times a week). Lung function was assessed by spirometry. Results: As many as 68 military soldiers were involved in this study which were divided into two groups, 38 people in the group 1 who routinely trained and 30 people in group 2 that did not routinely practice. Group 1 VEP1 values were higher than group 2 (p=0.03). No significant differences in terms of KVP, MVV and VO2max in both groups. Lung function of smokers were lower than non-smokers, but not statistically significant. Conclusion: There were significant differences in VEP1 values between military soldiers who routinely and did not routinely undergo 2-mile jogging exercises.
Accuracy Between CURB-65 Score and PSI in Determining The Prognosis of Community-Acquired Pneumonia Patients at H. Adam Malik General Hospital, Medan Fransisco Sentosa Pakpahan; Syamsul Bihar; Fajrinur Syarani; Putri Chairani Eyanoer
Respiratory Science Vol. 1 No. 3 (2021): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v1i3.25

Abstract

Background: Community-Acquired Pneumonia (CAP) is an important problem associated with morbidity and mortality. An accurate initial assessment is required before starting management of a CAP patient to determine the prognosis of the patient as early as possible. The CURB-65 score and PSI (Pneumonia Severity Index) are initial assessment scores that can be used. This study aimed to compare the accuracy between the CURB-65 score and the PSI in determining the prognosis in CAP patients at H. Adam Malik General Hospital Medan. Method: A descriptive study was conducted on 76 patients diagnosed with CAP. Each patient was assessed for their CURB-65 score, PSI class and mortality within 30 days of admission. Data were collected through patient medical records diagnosed CAP in 2018 and performed statistical analysis using 2x2 tables. Results: The CURB-65 ≥3 score showed accuracy (71.0%), sensitivity (53.8%), and specificity (89,2%). The CURB-65 ≥ 2 score showed accuracy (75.0%), sensitivity (82.1%), and specificity (67.6%).  Meanwhile, the Class IV-V PSI showed accuracy (77.6%), sensitivity (87.2%) and specificity (67.6%). Conclusion: The accuracy of the PSI is higher when compared to the CURB-65 score in determining the prognosis of CAP patients at H. Adam Malik General Hospital Medan. Although PSI is more accurate, CURB-65 is simpler, easier and less expensive to use
CT Guided TTNA and Core Biopsy in Suspected Lung Cancer, Review of Cases in Adam Malik General Hospital, Medan Hadi Suhendra; Fajrinur Syarani; Syamsul Bihar; Putri Chairani Eyanoer
Respiratory Science Vol. 2 No. 1 (2021): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i1.27

Abstract

ounds: The cytological and histopathological findings establish the type of lung cancer cells as the definitive diagnosis of lung cancer. This study aimed to determine the characteristics of lung cancer patients in terms of age, mean age, gender, staging, the proportion of lung cancer cells by cytologic examination of Transthoracic Needle Aspiration (TTNA) and histopathologic evaluation from CT-guided core biopsy. Method: This is a descriptive study involving 42 subjects diagnosed with lung cancer at H. Adam Malik Hospital Medan in 2016-2020 that met the inclusion criteria through consecutive sampling. Data was analysed using descriptive statistics for categorical variables. Results: Of 42 study subjects, the 60–71-year age group had the highest percentage of lung cancer (42.9%). Male (71.4%) was higher than female, the most common lung cancer staging was IVA (57.1%), and adenocarcinoma was found to be the most frequent type of lung cancer in both cytology (33.3%) and histopathology (31.0%). Conclusion: We concluded that core biopsy is superior in diagnosing lung cancer compared to TTNA.
Vitamin C Supplementation Improves Pulmonary Tuberculosis Patients' Sputum Conversion During Intensive Phase Category I Treatment in Medan Elok Ariyani Safitri; Parluhutan Siagian; Bintang Yinke Magdalena Sinaga; Putri Chairani Eyanoer
Respiratory Science Vol. 2 No. 2 (2022): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i2.30

Abstract

Background: Many factors influence the success of the acceleration of Acid-Fast Bacilli (AFB) sputum conversion in the treatment of the intensive phase of pulmonary tuberculosis (TB). One of these factors is the nutritional status or nutrition of pulmonary TB patients. Through a fenton reaction, Vitamin C is known to be able to sterilize Mycobacterium tuberculosis. This study aims to determine the effect of giving vitamin C on the conversion of AFB sputum in the intensive phase of pulmonary TB treatment. Method: This study was an inferential, quasi-experimental evaluation of the acceleration of AFB sputum conversion following vitamin C supplementation in patients with category I pulmonary TB. The study group was separated into two groups: 40 TB patients getting Anti Tuberculosis Treatment (ATT) with vitamin C, and 40 TB patients receiving ATT with placebo. Every two weeks, AFB sputum was examined, and vitamin C levels were measured before and after two months of therapy. Results: Conversion of AFB occurred sooner in the vitamin C group of pulmonary TB patients, with as many as 29 patients (72.5%) experiencing conversion of AFB sputum at the end of the second week of therapy, whereas there was no conversion in the placebo group. At the end of the fourth week, all patients (100%) given vitamin C showed AFB sputum conversion, whereas only eight patients (20%) in the placebo group had conversion at the end of the fourth week of treatment. Vitamin C levels increased significantly in the group of pulmonary tuberculosis patients who received vitamin C supplementation. Conclusion: Vitamin C supplementation in the treatment of pulmonary TB can accelerate the conversion of AFB sputum, which is statistically significant.
The Associations Between Severity Of Symptoms, D-Dimer and Incidence of ARDS In COVID-19 Herani Mutia Riandini; Fajrinur Syaran; Syamsul Bihar; Putri Chairani Eyanoer
Respiratory Science Vol. 2 No. 3 (2022): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i3.40

Abstract

Background: Severe acute respiratory injury caused by COVID-19 (ARDS) is a serious emerging complication. ARDS results from a cytokine storm that occurs in the second week of the disease course and acute-onset hypoxemia can be seen with bilateral infiltrates on chest radiograph. This study aimed to relate the severity of symptoms and D-dimer level to the incidence of ARDS in COVID-19 at H. Adam Malik Hospital as the referral center for COVID-19 in North Sumatra. Method: This was a descriptive study with a retrospective cohort design. The sample of this study was secondary data from medical records of positive RT-PCR COVID-19 patients from November 2020 to April 2021. The inclusion criteria were patients with moderate to critical COVID-19 cases with D-dimer examination taken from the first day of admission. Subjects were then followed up until discharge from the hospital to assess for ARDS episodes which were confirmed by the results of PaO2/FiO2 in arterial blood gases and bilateral infiltrations in chest X-Ray. The exclusion criteria were incomplete medical records. Results: The association between the severity of symptoms and the incidence of ARDS, 1 of which was found to be moderate, 19 cases were severe and 20 were critical. However, there was a statistically significant correlation between the severity of symptoms and the incidence of ARDS (P=0.0001). Conclusion: There was a significant correlation between the severity of symptoms and the D-dimer value on the incidence of ARDS.
Characteristics of COVID-19 Patients in Haji Adam Malik General Hospital, Medan, North Sumatera Dyana Destylya; Bintang YM Sinaga; Parluhutan Siagian; Putri Chairani Eyanoer
Respiratory Science Vol. 2 No. 3 (2022): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i3.53

Abstract

Background: Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). The increase in the number of COVID-19 cases was happening quite quickly and has spread between countries so that COVID-19 has become a pandemic in the world. This study aimed to determine the characteristics of COVID-19 patients at Haji Adam Malik General Hospital Medan. Method: This was a descriptive study. Data were taken from the medical records of 110 hospitalized patients with positive RT-PCR results for COVID-19 from December 2020 to April 2021. The inclusion criteria for the case samples were patients diagnosed with COVID-19 based on RT-PCR and the exclusion criteria were incomplete medical records. Characteristic analysis was carried out using the Kruskal Wallis test. Results: The most common comorbidities found in patients with severe COVID-19 were diabetes mellitus and HIV. The most common comorbidity found in moderate-level COVID-19 patients was pregnant women. The most common chest X-rays finding in severe and critical levels was bilateral infiltrates. Recovered patients were mostly obtained at moderate level, while deceased patients were mostly observed at critical levels. Conclusion: Characteristics of COVID-19 patients at Haji Adam Malik General Hospital were classified based on the degree of disease by age, lymphocyte value, N/L ratio, levels of CRP, D-dimer, procalcitonin, fibrinogen, ferritin, and comorbidities as well as the appearance of infiltrates in both lung fields.
Characteristics of Albumin Levels and Liver Function in Patients With COVID-19 at H. Adam Malik Hospital, Medan Ghazali Akhmad Putranta; Fajrinur Syarani; Syamsul Bihar; Putri Chairani Eyanoer
Respiratory Science Vol. 3 No. 1 (2022): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i1.61

Abstract

Background: COVID-19 (Corona Virus Disease-2019) pandemic has a high mortality rate especially in Medan, Indonesia. Serum albumin and liver function tests are believed to be predictive biomarkers for prognosis in patients with infectious diseases, including COVID-19. This study aimed to investigate the association between the mortality events and severely ill COVID-19 patients' serum albumin and liver enzymes. Method: This is a cross-sectional study using secondary data from the medical records of H. Adam Malik Hospital patients with COVID-19 who were confirmed by RT-PCR from August to December 2020. All patients were analyzed for age, sex, hypoalbuminemia, increased liver enzymes and outcome using Chi-square tests (P<0.05). Results: The average age of severe COVID-19 patients at H. Adam Malik Hospital ranged from 41 to 60 years, with more women prevalence than men. Most of the patients had hypoalbuminemia (84.2%), an increase in AST (59.4)% and ALT (45.5%). There was no significant association between hypoalbuminemia and the disease outcome (P=0.12). There was a significant association between elevated liver enzymes and mortality in severely ill COVID-19 patients (P<0.001). Conclusion: We found that hypoalbuminemia is common in patients with severe COVID-19. However, we found that albumin levels had no association with the patients' mortality rate. Liver enzymes levels appear to be a predictive biomarker for outcomes in COVID-19 patients of H. Adam Malik Hospital. We found that higher ALT and AST levels were associated with significantly higher mortality.
Inflammatory Markers of ARDS Events among Patients with Severe and Critical COVID-19 Infection at Adam Malik General Hospital, Medan, North Sumatera Eva Susanti Debora Hutabarat; Fajrinur Syarani; Syamsul Bihar; Putri Chairani Eyanoer
Respiratory Science Vol. 3 No. 3 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i3.78

Abstract

Background: COVID-19 can cause fatal outcomes, especially acute respiratory distress syndrome (ARDS). It manifests as organ dysfunction during COVID-19's hyperinflammatory phase, which is associated with a high mortality rate. Data on the clinical characteristics and inflammation markers of patients with severe and critical degrees of COVID-19 with ARDS events are limited. Method: This study is carried out at the Haji Adam Malik General Hospital in Medan. We grouped 204 medical records from February to July 2022 of hospitalized patients with severe and critical COVID-19 cases into two groups, ARDS and non-ARDS. Characteristics of demographic and laboratory inflammatory markers upon admission between each group were collected. After collecting data and serving as categorical data in the frequency distribution table by SPSS ver 25.0. Results: We identified 116 patients (56.9%) who had ARDS event upon hospital admission. ARDS event are most commonly found in the elderly group and the median age of ARDS group patients was 59.5 years higher than the non-ARDS group. Male patients were more likely to have ARDS than female patients. Compared with the non-ARDS group, ARDS group patients had lymphocytopenia, neutrophilia, increased neutrophil-to-lymphocyte ratio (NLR), Procalcitonin and C-Reactive Protein levels. Conclusion: Lymphocytopenia, neutrophilia, increased NLR, procalcitonin and CRP levels upon admission revealed that they were higher in ARDS patients compared to non-ARDS patients. It is critical to identify high-risk groups, such as male sex, the elderly, those with comorbidities, and patients with impaired inflammatory markers to prevent severe complications from COVID-19.
Co-Authors -, Fadhlia Ade Rahmaini Adlin Adnan Alona, Ivana Alwi Thamrin Nasution Amaiappan, Jesvinder Andika Pradana Andika Pradana Andika Pradana Arieta, Lydia Arlinda Sari Wahyuni Armon Rahimi Asnir, Rizalina Arwinati Azali, Chairul Nurdin Azizah Ghanie Icksan Bintang Yinke Magdalena Sinaga Bintang Yinke Magdalena Sinaga Bintang YM Sinaga Bintang YM Sinaga Budi Jefri Budi Wiweko Chairiza Muttaqien Dana Jauhara Layali Delfitri Munir Delfitri Munir Delores Elisabeth Sormin Destylya, Dyana Dyana Destylya Eddy Bangun Elisabeth Elisabeth Elizabeth Napitupulu Elmeida Effendy Elok Ariyani Safitri Elva Susanty Elvita Rahmi Daulay Endy Juli Anto Endy Todo Sirait endyjulianto endyjulianto Eva Susanti Debora Hutabarat Evo Elidar Harahap Fachrezi, Muhammad Alfian FAHDI, FIRDAUS Fajrinur Syahrani Fajrinur Syahrani Fajrinur Syaran Fajrinur Syarani Fajrinur Syarani Fajrinur Syarani Faradila, Devita Farhat, Farhat Faried, Mukhamad Febiyanti, Mica Felisia Felisia Firdaus, Ruby Fransisco Sentosa Pakpahan Fujiati, Isti Ilmiati Ganda M. Leonard Samosir Ghazali Akhmad Putranta Ginting, Franciscus Hadi Suhendra Hafizhalaila Ammar Hakim, Enggrek Pelita Hamdi, Tasrif Harahap, Juliandi Haryuna, Tengku Siti Hajar Hasibuan, Mangain Hemma Yulfi Hendri Wijaya, Hendri Henny Maisara Sipahutar Herani Mutia Riandini Hidayat Hidayat Ihsan, Mhd. Joshua Asley Juli Anto, Endy Juliandi Harahap Kadri, Alfansuri Kartini harahap Kembaren, Tambar kenvin rusli Kiking Ritarwan Listyoko, Aditya Sri Lubis, Muhammad Allif Syafrin Lubis, Netty Delvrita Maesyara Adinda Sari Maulidina Hsb, Putri Sari Muhammad Ichwan Muhammad Zainul A Muntasir Abdullah Nababan, Windika Nasution, Duma Ratna Sari Netty Delvrita Lubis Netty Delvrita Lubis Noni Novisari Soeroso Noni Novisari Soeroso Noni Novisari Soeroso Nurdiansah, Firman Nurul Citta Banu Putri Nurul Ramadhani Nuryunita Nainggolan Octavia, Nur Afni Heryanti Pandia, Pandiaman Pandiaman Pandia Pandiaman Pandia Panjaitan, Alfred Johnatan Pardede, Sujahn Anto Parluhutan Siagian Parluhutan Siagian Parluhutan Siagian Pase, M Aron Pendiaman Pandia Perangin-angin, Gwanita Nawariantina Peter Peter Pratama, Mhd. Rizki Pratiwi, Ade Dwi R.A Henny Anggriani Ramadhani, Adini Arifah Rambe, Andrina Yunita Murni Restuti Hidayani Saragih Ribawanto, Muhammad Rafif Rifda Hayati Rina Amelia Rina Yunita Ririe Fachrina Malisie Risqin, Muhammad Anas Fatah Rosita Juwita Sembiring Salsabila, Anisa Samodra, Yoseph Leonardo Sarah, Dewi Maya Sekali, Oktaviani Karo Selvy Wulandari Siahaan, Jekson Martiar Sikumbang, Rahmat Hidayat Sinaga, Bintang Yinke Magdalena Sinaga, Joshua Princeman Sinaga, Sudirman Parningotan Sirait, Asima Rodiarta Siregar, Nondang Purnama Syamsul Bihar Syamsul Bihar Syamsul Bihar Syarani, Fajrinur Tarigan, Amira Permatasari Tarigan, Setia Putra Tri Setia Negara Sinulingga Vera, Yeni Wahyuni, Arlinda Sari Wan Betty Pratiwi Yahwardiah Siregar Yessi Andriani Zainal Yunanda, Yuki Zainuddin Amir Zakirah, Sarah Chairani