Claim Missing Document
Check
Articles

Found 34 Documents
Search

Effectiveness of Antibiotic Use in the Prevention and Treatment of Respiratory Tract Infections Andika Alfiansyah; Fadli Fadli; Lutvi Anggraeni; Khrisna Agung Cendekiawan
Journal of Pharmacopoeia Vol. 2 No. 1 (2025): MARCH-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/6tqjqh98

Abstract

This study aims to analyze the effectiveness of the use of antibiotics in the prevention and treatment of respiratory tract infections. This study uses the Systematic Literature Review (SLR) method. There are three stages carried out in mapping the effectiveness of antibiotic use in the prevention and treatment of respiratory tract infections, namely: 1) harvesting data, 2) screening data, and 3) Data Analysis and Visualization. This study uses a database from Scopus with scientific journals as many as 9 articles from the range of 2021 to 2024. The effectiveness of antibiotic use in the prevention and treatment of respiratory tract infections is influenced by a variety of factors, including patient adherence, duration of therapy, and vaccine availability and use. Excessive or improper use of antibiotics can increase bacterial resistance, so more sustainable strategies, such as vaccination and stricter antibiotic use policies, are needed to improve the effectiveness of prevention and treatment of respiratory tract infections. The implications of this study are expected to be useful for future researchers and can be used in clinical applications
Antibiotics And Bacterial Resistance: A Global Challenge That Needs To Be Addressed Sugiah Sugiah; Fadli Fadli; Fitria Hariati; Khrisna Agung Cendekiawan
Journal of Pharmacopoeia Vol. 2 No. 1 (2025): MARCH-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/mwb7an91

Abstract

This study aims to explore the global challenges faced in addressing bacterial resistance to antibiotics, which are now one of the most serious health threats in the world. This study was conducted through the Systematic Literature Review (SLR) method by searching scientific articles from various databases such as PubMed, Scopus, and Google Scholar using the keywords "antibiotic resistance", "global health", "treatment failure", and "resistance mechanisms". The articles analyzed are publications in the last 10 years, focusing on the causes of resistance, their impact on global health, and countermeasures that have been carried out. The results of the study show that antibiotic resistance is mainly caused by the inappropriate use of antibiotics in the medical and non-medical sectors, lack of distribution supervision, and lack of development of new antibiotics. To overcome this, a comprehensive approach is needed, including increasing public education and health workers, strengthening regulations, and developing alternative therapies such as phagotherapy and vaccines. Without proper treatment, antibiotic resistance can lead to infection treatment failure, increased mortality rates, and burden the global health system
Potential Hyperglycemia In Type 2 Diabetes Mellitus Patients Due To Drug Interactions At Hospital Avrillana Dewangi Gea Ayunda Diarso; Shinta Mayasari; Khrisna Agung Cendekiawan
Indonesian Pharmacopeia Journal Vol. 1 No. 2 (2024): July
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v1i2.19

Abstract

Background: Hyperglycemia is a medical condition in the form of an increase in blood glucose levels beyond normal limits with a blood sugar concentration of ≥200 mg/dl. Hyperglycemia that is not well controlled can cause serious disorders of the body's systems, especially the nerves and blood vessels. Based on WHO data, the prevalence of type 2 DM with the potential for hyperglycemia in the world in 2019 was 5.3%. This figure is expected to increase to 6.3% in 2030. Objective: This research was conducted to determine the potential for hyperglycemia in type 2 diabetes mellitus patients due to drug interactions at one of hospital in Jember. Method: This research uses a quantitative design with retrospective data collection, namely research obtained based on information from patient medical records. The population in this study was 539 patients suffering from type 2 diabetes mellitus for the period January-December 2022. The sample from this study was type 2 diabetes mellitus patients who met the inclusion criteria. Sampling was calculated using the Slovin formula using random sampling techniques and the results obtained were 84 medical record samples. Analysis using univariate. Data is displayed in frequency and percentage form. Data processing uses Microsoft Excel and SPSS. Results: Most of the drugs received by type 2 diabetes mellitus patients experienced interactions that had the potential to cause hyperglycemia with blood sugar levels ≥200 mg/dl (96.43%) and a moderate clinical significance level of 70.24%. Conclusion: There is a potential for hyperglycemia caused by diabetes drug interactions. Monitoring drug interactions and effective treatment in patients with type 2 diabetes mellitus needs to be carried out to achieve optimal therapy targets and increase awareness of healthy lifestyles in diabetes management.
Potential Hypoglycemia in Patients With Type 2 Diabetes Mellitus Due to Drug Interactions in Citra Husada Hospital Elisa wardatul awaliya; shinta mayasari; khrisna agung cendekiawan
Indonesian Pharmacopeia Journal Vol. 1 No. 2 (2024): July
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v1i2.24

Abstract

Diabetes mellitus (DM) is a metabolic disorder disease characterized by an increase in blood glucose due to decreased insulin secretion by pancreatic beta cells, insulin disorders or resistance. The main risks that are commonly found in every patient diagnosed with DM disease include hypoglycemia. In a study conducted at a public hospital in Jakarta, 186 incidents of interaction of antidiabetic drugs with other drugs that have hypoglycemia potential with a moderate clinical significance level of 83.8% were found. The potential for drug interactions in DM patients is still very frequent. This can be caused by the number of drugs that are often used (Polipharmacy or multiple drug therapy). The purpose of this study is to identify the potential for hypoglycemia in type 2 DM patients due to drug interactions at Citra Husada Jember hospital. This type of research is qualitative research with retrospective data collection. The design of this study uses a cross-sectional design. The population of this study is 662 medical record data of outpatients with type 2 diabetes for the period of January – December 2022. Data analysis uses univariate analysis. In this study, most patients have the potential to experience hypoglycemia.