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All Journal e-Journal Pustaka Kesehatan Pharmaciana: Jurnal Kefarmasian Majalah Obat Tradisional Multidiciplinary Journal MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Jurnal Mandala Pharmacon Indonesia Jurnal Farmamedika (Pharmamedica Journal) Jurnal Ilmiah Edunomika (JIE) Jurnal Ilmiah Farmako Bahari BERNAS: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmiah Pamenang (JIP) Medfarm: Jurnal Farmasi dan Kesehatan Eureka Herba Indonesia Natural Sciences Engineering and Technology Journal Jurnal Pengabdian Masyarakat Madani Jurnal EduHealth INDRA: Jurnal Pengabdian kepada Masyarakat Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi JOMPA ABDI: Jurnal Pengabdian Masyarakat Journal of Pharmaceutical and Sciences. Journal of Economics and Public Health Jurnal Kesehatan dr. Soebandi Journal of Pharmacopoeia Dirya : Journal of Economic Management Sadewa: Jurnal Pengabdian Masyarakat Journal of Pharmacopoeia Indonesian Pharmacopeia Journal (IPJ) Halal Science Jurnal Farmasi Islam Kalimantan Jurnal teknologi Kesehatan Borneo Biodiversitas Journal of Biological Diversity Journal of World Future Medicine, Health and Nursing
Khrisna Agung Cendekiawan
Bachelor’s Degree Program In Pharmacy, Faculty Of Health Sciences., Universitas Dr. Soebandi, Indonesia
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Application Mobile Health For Education And Prevention Stunting Mayasari, Shinta; Nafisah Isnawati; Khrisna Agung Cendekiawan
Jurnal EduHealth Vol. 15 No. 03 (2024): Jurnal EduHealt (September), Year 2024
Publisher : Sean Institute

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Abstract

Background: Stunting is a chronic nutritional problem that can interfere with a child's growth because it causes the child's height to not match his age or to be shorter. In 2021, Jember was ranked second in the East Java region with a score of 37.08%. ANTING is a mobile health-based Stunting Care Pharmacist which contained educational features and stunting prevention, one of which is through fulfilling clinical nutrition. Research Objective: The purpose of this study was to measure the increase in knowledge of families of stunting patients through mobile health-based education. Methods: This research was conducted at a health service facility in one of the sub-districts of Jember district. The research target was the families of stunting patients. This research used a quasy experiment with one group, pre and post test design. Researchers will carry out pre-test measurements from the beginning of the measurement and post-test on the same group at the last measurement. The sampling technique was accidental sampling for one month with a total of 32 samples. Results: The results of the study showed that there was an increase in the knowledge of stunting patients' families after receiving education through the media of mobile health applications which is marked p value 0,004.Conclusions: This ANTING provided some information related to stunting, especially in terms of preventing stunting, so that it has a positive effect on reducing the development of stunting rates.
Pharmacological Effects of Curcumin in Chronic Inflammatory Therapy Muntasir, Muntasir; Faradina, Anggia; Wuryandari, Tutik; Cendekiawan, Khrisna Agung
Journal of Pharmacopoeia Vol. 2 No. 1 (2025): MARCH-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/r1y2wm33

Abstract

Herbal plants Herbal plants in Indonesia have an important role in traditional medicine and public health. The study aims to evaluate the effectiveness and mechanism of action of curcumin in chronic inflammatory therapy. This study employs the Systematic Literature Review (SLR) methodology.. This study uses a database from Scopus of 9 Scopus articles from the range of 2020 to 2025. There are three stages carried out in mapping the effectiveness and mechanism of action of curcumin in chronic inflammatory therapy, namely data harvesting, screening data and Data Analysis and Visualization. The results obtained are that curcumin is effective in chronic inflammatory therapy by inhibiting the main inflammatory pathways (NF-ƙB and JAK/STAT), has antioxidant effects, accelerates tissue regeneration, and functions as an immunomodulator. However, the limited bioavailability of curcumin presents a significant challenge in its application. Nanoformulation technology and its combination with compounds like CMPs can enhance its effectiveness in clinical therapy.The implications of this research are directed to researchers, the community and the government
Effectiveness of Antibiotic Use in the Prevention and Treatment of Respiratory Tract Infections Alfiansyah, Andika; Fadli, Fadli; Anggraeni, Lutvi; Cendekiawan, Khrisna Agung
Journal of Pharmacopoeia Vol. 2 No. 1 (2025): MARCH-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/6tqjqh98

Abstract

This study aims to analyze the effectiveness of the use of antibiotics in the prevention and treatment of respiratory tract infections. This study uses the Systematic Literature Review (SLR) method. There are three stages carried out in mapping the effectiveness of antibiotic use in the prevention and treatment of respiratory tract infections, namely: 1) harvesting data, 2) screening data, and 3) Data Analysis and Visualization. This study uses a database from Scopus with scientific journals as many as 9 articles from the range of 2021 to 2024. The effectiveness of antibiotic use in the prevention and treatment of respiratory tract infections is influenced by a variety of factors, including patient adherence, duration of therapy, and vaccine availability and use. Excessive or improper use of antibiotics can increase bacterial resistance, so more sustainable strategies, such as vaccination and stricter antibiotic use policies, are needed to improve the effectiveness of prevention and treatment of respiratory tract infections. The implications of this study are expected to be useful for future researchers and can be used in clinical applications
Antibiotics And Bacterial Resistance: A Global Challenge That Needs To Be Addressed Sugiah, Sugiah; Fadli, Fadli; Hariati , Fitria; Cendekiawan, Khrisna Agung
Journal of Pharmacopoeia Vol. 2 No. 1 (2025): MARCH-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/mwb7an91

Abstract

This study aims to explore the global challenges faced in addressing bacterial resistance to antibiotics, which are now one of the most serious health threats in the world. This study was conducted through the Systematic Literature Review (SLR) method by searching scientific articles from various databases such as PubMed, Scopus, and Google Scholar using the keywords "antibiotic resistance", "global health", "treatment failure", and "resistance mechanisms". The articles analyzed are publications in the last 10 years, focusing on the causes of resistance, their impact on global health, and countermeasures that have been carried out. The results of the study show that antibiotic resistance is mainly caused by the inappropriate use of antibiotics in the medical and non-medical sectors, lack of distribution supervision, and lack of development of new antibiotics. To overcome this, a comprehensive approach is needed, including increasing public education and health workers, strengthening regulations, and developing alternative therapies such as phagotherapy and vaccines. Without proper treatment, antibiotic resistance can lead to infection treatment failure, increased mortality rates, and burden the global health system
PEMBERDAYAAN PEMBUATAN SABUN CUCI PIRING BERBAHAN HERBAL ANTIMIKROBA PADA IBU-IBU RUMAH TANGGA DI KABUPATEN JEMBER Lindawati Setyaningrum; Sholihatil Hidayati; Wima Anggitasari; Aliyah Purwanti; Diah Yuli Pangesti; Khrisna Agung Cendekiawan; Iski Weni Pebriarti; Shinta Mayasari; Dina Trianggaluh Fauziah; Nafisah Isnawati; M. Rofik Usman; Dhina Ayu Susanti
Jurnal SADEWA Vol 2 No 02 (2024): Sadewa: Jurnal Pengabdian Masyarakat
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/js.v2i2.812

Abstract

Soap is a material used for washing clothes, furniture, the body, etc. which is made from a mixture of alkali and triglycerides from fat. However, as time goes by, today's people are using ready-to-use sponges and washing soap in various forms and their respective advantages. Currently, many dishwashing soaps use herbal ingredients as their active substances. Coriander seeds and orange oil are herbal ingredients that can be used as antibacterial ingredients which can be used as active ingredients in making dishwashing soap. The village community's lack of knowledge regarding herbal ingredients and how to make dish soap has closed down business opportunities in Kopang Kebun Hamlet, Kemuning Lor Village, Arjasa District, Jember Regency. Therefore, village communities need training to process these herbal ingredients into products that are safe for the environment. The aim of this program for making liquid dish washing soap is to empower the women of Kopang Kebun Hamlet, most of whom are housewives, so that with this outreach, the community can make their own liquid soap to meet their daily needs and can also be used as a home industry.
Peningkatan Pengetahuan Pemanfaatan Tanaman Berkhasiat Obat Daun Jambu Biji (Psidium guajava) Pada Masyarakat Suku Osing Kabupaten Banyuwangi Cendekiawan, Khrisna Agung; Isnawati, Nafisah; Anggraeni, Lutvi; Pangesti, Yuli; Mayasari, Shinta
BERNAS: Jurnal Pengabdian Kepada Masyarakat Vol. 6 No. 2 (2025)
Publisher : Universitas Majalengka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31949/jb.v6i2.13089

Abstract

Pulau Jawa merupakan pulau yang kaya keanekaragaman hayati. Obat tradisional pada etnis Suku Osing umumnya masih dalam bentuk yang sederhana. Bahan baku yang diambil dari alam setelah dibersihkan biasanya langsung digunakan dalam bentuk segar dengan cara direndam atau direbus kemudian diminum, diolah dengan cara dihaluskan dan ditumbuk/dipanaskan dalam bungkusan daun. Pengetahuan dan pemanfaatan tanaman obat masih minim terutama dalam pengolahannya menjadi sediaan yang efektif dan efisien agar mudah digunakan. Jambu Biji (Psidium guajava) merupakan tumbuhan yang dapat dimanfaatkan sebagai obat tradisional terutama pada bagian daunnya. Tujuan dari kegiatan ini untuk meningkatkan pengetahuan warga tentang khasiat tanaman Jambu Biji sekaligus mendorong warga memanfaatkan lahan pekarangan rumah untuk menanam tanaman tersebut sebagai tanaman obat keluarga serta dapat mengolah simplisia Jambu Biji sebagai teh herbal untuk digunakan menjadi minuman berkhasiat obat. Metode yang digunakan adalah sosialisasi, edukasi materi tentang Daun Jambu Biji dan pelatihan pembuatan teh herbal. Edukasi dilakukan dengan mengukur tingkat pengetahuan menggunakan kuesioner yang dibagikan sebelum (pretest) dan sesudah (post-test) pemberian materi. Hasil pretest menunjukkan bahwa pengetahuan dan minat warga untuk membudidayakan tanaman Jambu Biji masih kurang. Namun pada hasil post-test menujukkan pengetahuan mereka menjadi meningkat. Kesimpulan dari kegiatan ini terdapat peningkatan pengetahuan warga tentang tanaman berkhasiat obat Daun Jambu Biji (Psidium guajava)
FORMULASI DAN EVALUASI SEDIAAN GEL EKSTRAK KULIT BAWANG PUTIH (Allium sativum) SERTA UJI AKTIVITAS ANTIBAKTERI TERHADAP Propionibacterium acnes: FORMULATION AND EVALUATION OF GEL PREPARATION OF GARLIC (Allium sativum) PEEL EXTRACT AND ANTIBACTERIAL ACTIVITY TEST AGAINST Propionibacterium acnes" nafisah isnawati; Nuraini, April; Agung , Khrisna; Anggraeni, Lutvi; Nufus, Galuh Maulidatun; Dwi, Jacinta
Jurnal Ilmiah Pamenang Vol. 7 No. 1 (2025): Jurnal Imiah Pamenang (JIP)
Publisher : Stikes Pamenang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53599/jip.v7i1.307

Abstract

Abstrak   Bawang putih (Allium sativum) merupakan sumber potensial sebagai agen terapeutik yang mempunyai aktivitas antibakteri terhadap bakteri Propionibacterium acne. Propionibacterium acne merupakan salah satu bakteri  penyebab terjadinya jerawat yang hidup di kulit, khususnya di area kelenjar minyak. Penatalaksaan jerawat diantaranya menggunakan antibiotik, baik yang topikal maupun sediaan oral. Penggunaan antibiotik jangka panjang dan penggunaan yang tidak sesuai bisa menyebabkan resistensi, selain itu juga menimbulkan efek samping seperti iritasi, gatal, dan terasa panas. Kulit bawang putih (Allium sativum) merupakan simplisia yang mengandung metabolit sekunder seperti saponin, terpenoid, alkaloid, dan flavonoid. Tujuan penelitian ini formulasi dan evaluasi mutu fisik sediaan gel dan uji aktivitas antibakteri terhadap bakteri Propionibacterium acne.  Metode penelitian ini adalah laboratory eksperiment. Sampel kulit bawang putih diekstraksi menggunakan metode maserasi dengan pelarut etanol 70%. Jumlah zat aktif yang digunakan dengan variasi konsentrasi F1 (5%), F2 (10%) dan F3 (15%) dan F0 (0%). Sediaan gel yang dihasilkan dilakukan evaluasi mutu fisik meliputi organoleptis, homogenitas, pH, daya sebar daya lekat dan uji aktivitas antibakteri.  Hasil penelitian menunjukkan ketiga formula sediaan gel ekstrak kulit bawang putih dengan berbagai konsentrasi yang berbeda memenuhi syarat rentang yang diperbolehkan SNI. Daya hambat sediaan gel pada setiap formula semakin banyak kandungan ekstrak maka daya hambat semakin tinggi, dari ketiga formula daya hambat antibakteri memiliki kategori kuat. Abstract     Garlic (Allium sativum) is a potential therapeutic agent with antibacterial activity against Propionibacterium acnes. Propionibacterium acnes is one of the bacteria that cause acne and resides on the skin, particularly in oil gland areas. Acne management includes the use of antibiotics, both topical and oral. However, long-term and improper use of antibiotics can lead to resistance and cause side effects such as irritation, itching, and burning sensations. Garlic skin (Allium sativum) is a simplisia containing secondary metabolites such as saponins, terpenoids, alkaloid and flavonoid. he aim of this study is the formulation and evaluation of the physical quality of the gel preparation and the antibacterial activity test against Propionibacterium acnes. This research used a laboratory experimental method. Garlic skin samples were extracted using the maceration method with 70% ethanol as the solvent. The amount of active substance used varied with different concentrations: F1 (5%), F2 (10%), F3 (15%), and F0 (0%). The resulting gel preparations were evaluated for physical quality, including organoleptic properties, homogeneity, pH, spreadability, adhesiveness, and antibacterial activity. The results showed that the three garlic peel extract gel formulas with different concentrations met the requirements within the allowable SNI range. The inhibitory power of the gel preparations increased with higher extract content. Among the three formulas, the antibacterial inhibitory power was categorized as strong
The Role of Information Technology and Product Innovation on the Competitive Advantage of Companies at Jember East Java Cendekiawan, Khrisna Agung; Wardhani, Firdha Aprillia
JAKI : Jurnal Akuntansi Vol 2 No 1 (2025): Dirya : Journal of Economic Management
Publisher : Pascasarjana STIE Miftahul Huda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70283/dirya.v2i1.76

Abstract

This study aims to analyze the role of information technology and product innovation in creating a competitive advantage for companies in Jember, East Java. Competitive advantage is a critical factor in determining the survival and success of companies in an increasingly competitive market. Using a qualitative research method, this study explores the perspectives of key stakeholders within companies regarding the implementation of information technology and product innovation. In-depth interviews with company leaders, along with secondary data analysis, were employed to gain insights into how these two factors contribute to the company’s strategy. The findings of this study reveal that information technology plays a crucial role in enhancing operational efficiency, internal communication, and facilitating access to global markets. Additionally, product innovation proves to be a key differentiator for companies, enabling them to meet the ever-evolving needs of consumers. The research also highlights that companies successfully integrating both elements are able to build and sustain a competitive advantage. Overall, the findings demonstrate the importance of adapting to new technologies and continuously innovating in order to maintain a company’s competitiveness in the digital era.
Membangun ketahanan masyarakat terhadap stroke: edukasi, pendampingan dan pembentukan kader pencegahan Stroke Isnawati, Nafisah; Agung C., Khrisna; Nuraini, April; Khoirun N., Hilda
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 6 No. 1 (2025): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/indra.v6i1.466

Abstract

Stroke is one of the diseases that causes the highest rates of death and disability in the world, including in Indonesia. This condition is often caused by preventable risk factors, such as hypertension, diabetes, high cholesterol, and unhealthy lifestyles. However, the low level of public understanding regarding risk factors and early symptoms of stroke has led to a high incidence of strokes that are not properly treated. Therefore, this community service activity aims to provide education on stroke prevention, recognizing early symptoms, and the importance of immediate treatment This activity was conducted through community health education sessions, basic health screenings such as blood pressure and blood sugar tests, and a campaign on the importance of a healthy lifestyle. The education focused on increasing public awareness of stroke warning signs and understanding stroke prevention and management. The results of this activity showed an improvement in the community's understanding of stroke risk factors and preventive actions that can be taken, as evidenced by pre-test and post-test results, which indicated a difference in knowledge before and after the activity.From the results of the community service participant characteristics, 76.3% were female, and the majority of participants fell into the young elderly category, aged between 66-74 years, accounting for 50.8%. The results of self-administered health tests showed that 28% of participants had normal levels, 18.6% had uric acid levels above normal, 5.1% had cholesterol levels above normal, and 6.8% had blood sugar levels above normal (prediabetes and diabetes). Blood pressure issues were found in 42.4% of participants, 84.7% were categorized as overweight according to their BMI, 67.8% had low muscle mass, 86.4% had high-risk visceral fat, 91.5% had high body fat, and 84.7% showed abnormalities in Basal Metabolic Rate (BMR) and body age.
Overview of Blood Pressure Changes in Hypertensive Patients using Valsartan at One of Hospital in Jember District Alvia Putri Priyono, Rosyidatul; Mayasari, Shinta; Khrisna Agung C
Jurnal EduHealth Vol. 16 No. 03 (2025): Jurnal EduHealt, Edition July - September , 2025
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hypertension is a major global health issue contributing to cardiovascular disease, stroke, kidney failure, and premature death. Its prevalence continues to rise both globally and in Indonesia. Effective management often involves pharmacological treatment, with valsartan, an angiotensin II receptor blocker (ARB), widely used due to its efficacy and safety profile. This study aims to describe blood pressure changes in hypertensive patients treated with valsartan at one of hospital at Jember district. A descriptive observational study was conducted using medical records of patients receiving valsartan therapy from January to October 2022. A total of 4,907 patients were recorded, making hypertension one of the top ten most frequent diagnoses in the hospital. Results showed that valsartan effectively reduced both systolic and diastolic blood pressure, with most patients achieving target levels after treatment. These findings suggest that valsartan is effective in managing hypertension and preventing complications when properly administered and adhered to. Continued monitoring and appropriate treatment selection remain essential for optimal patient outcomes.
Co-Authors Agus Mukholid Ahmad Robittah Alfiansyah, Andika Aliyah Purwanti Alvia Putri Priyono, Rosyidatul Amalia Wardatul Firdaus Ancah Caesarina Novi Marchianti Andika Alfiansyah Andro Ruben Runtu Anggia Faradina Anggraeni, Linda Suci Anggraeni, Lutvi Anggraeni, Lutvi Anggraeni April Nuraini Arnes Yuli Vandika Atmanita Khairomatul L Avrillana Dewangi Gea Ayunda Diarso Ayu Angger Putri M. Sholeh Bambang Kuswandi Benny Novico Zani Dea Maulidi Saputri Dewa Ngakan Gde Wahyu Mahatma Putra Dhina Ayu Susanti Diah Yuli Pangesti Diana Kholifah Dina Rasmita Dina Trianggaluh Fauziah Dwi, Jacinta Dyan Wigati Elisa wardatul awaliya Endang Lifchatullaillah Fadli Fadli Fadli Fadli Fadli Fadli Faradina, Anggia Fitria Hariati Florentinus Dika Octa Riswanto Hariati , Fitria Hasana, Siti Nur HELMALIA HELMALIA, HELMALIA Heru Sulistijono Heru Sulistijono Iski Weni Pebriarti Islami, Nurul Ariffaeni Khoirun N., Hilda Kintoko Kintoko Kintoko Kintoko Kintoko KINTOKO KINTOKO Kintoko Kintoko Kintoko, Kintoko Lia Fitriyaningrum Linda Suci Anggraeni Linda Suci Anggraeni lindawati setyaningrum Lutvi Anggraeni Lutvi Anggraeni Anggraeni M. Rofik Usman Minarti Minarti Minarti Minarti Muhamad Risal Tawil Muntasir, Muntasir Nafisah Isnawati Neny Poerwahyuningrum Neny Poerwahyuningrum Nia Kristiningrum Ningrum, Lailatul Fitria Nufus, Galuh Maulidatun Nuraini, April Nurul Ariffaeni Islami Pangesti, Yuli Putra, Dewa Ngakan Gde Wahyu Mahatma Rasmita, Dina Rensi Suryanti Rina Fitriana Riski Eko Ardianto Runtu, Andro Ruben Santoso, Blegoh Iwan Sapto Yuliani SAPTO YULIANI Sapto Yuliani Sapto Yuliani Savania Alifianty Hafzah, Savania Setyorini, Dhiana Shinta Mayasari Shinta Mayasari Sholihatil Hidayati Siti Nur Hasana Siti Nur Hikmah Sugeng Winarso Sugiah Sugiah Sugiah, Sugiah Suryanti, Rensi Susanti, Dhina Ayu Tutik Wuryandari Wardhani, Firdha Aprillia Wulandari, Hilwiyah Septi Wuryandari, Tutik Zani, Benny Novico Zulkarnain Permana