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Clinical profile of diabetic foot ulcer patients in referral hospital Jambi: A-cross sectional study Fitrianingsih, Fitrianingsih; Sania, Gina; Maimum, Maimum
Riset Informasi Kesehatan Vol 14 No 3 (2025): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/rik.v14i3.1039

Abstract

Background: Diabetic foot ulcer (DFU) is a chronic complication of diabetes mellitus (DM) and remains a significant challenge in morbidity, mortality, and disability among diabetic patients. This study aims to identify the sociodemographic and clinical characteristics of hospitalized DFU patients at Raden Mattaher General Hospital, Jambi. Method: This retrospective cross-sectional study was conducted at Raden Mattaher General Hospital, Jambi, Indonesia. A total of 31 patients data were collected from the medical records of DFU patients hospitalized at Raden Mattaher General Hospital in 2022. The variables observed were age, sex, residence, comorbidities, type of DM, random blood glucose levels (RBG), amputation rate, mortality, and length of stay (LOS). Results: The mean age of DFU patients was 55.6 ± 12.6 years, with females accounting for the majority (67.7%). Most patients lived outside Jambi City (74.2%), with more than one comorbidity (48.4%). All patients had type 2 diabetes mellitus (100.0%) with RBG level of 303.8 ± 205.8 mg/dL (mean±SD), amputation rate (19.4%), mortality rate (12.9%), and the mean LOS was 10.3 ± 6.9 days. Conclusion: This study indicates that most DFU patients have multiple comorbidities and poorly controlled blood glucose levels, which contribute to a higher risk of amputation, mortality, and prolonged hospitalization.
Green synthesis nanoperak menggunakan ekstrak batang dadap serep (Erythrina Subumbrans (Hassk.) Merr) Maharini, Indri; Fitrianingsih, Fitrianingsih; Utami, Diah Tri
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.410

Abstract

Dadap serep stems contain secondary metabolite compounds of flavonoids, saponins, isoflavonoids, alkaloids and lectins which can act as reducing agents in the biosynthesis of nanosilver. This research aims to determine the effect of the concentration of liquid extract of dadap serep stem on the green synthesis silver nanoparticle (AgNPs) process. The aqueous extract of dadap serep stem reacted with one mM AgNO3 in a ratio of volume 1: 1 (FI), 1: 2 (FII), and 2: 1 (FIII). Characterization of AgNPs includes Surface Plasmon resonance (SPR) using UV/Vis spectrophotometer at wavelengths of 300-700 nm, particle size, and zeta potential using a particle size analyzer (PSA). The result showed that the SPR of AgNP values is 429-436 nm. AgNPs FI, II, and III particle sizes were 66.13 nm, 75.76 nm, and 75.96 nm, respectively. The PDI values below 0.5 confirmed that the distribution of nanoparticles was uniform. The most stable nanoparticle is Formula I.
Effectiveness of an Organic Mask of Moringa Leaves (Moringa oleifera) and Turmeric (Curcuma longa) for Facial Care Agusriani, Agusriani; Hamilatussa'diyah, Hamilatussa'diyah; Azizah, Lailan; Fitrianingsih, Fitrianingsih
Jurnal Kefarmasian Indonesia VOLUME 14, NUMBER 2, AUGUST 2024
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Facial masks are cosmetic products for topical use on facial skin. Using organic components from nature can prevent irritation and skin pigment damage due to the side effects of harmful chemicals in cosmetic products in the global market. This study aims to develop a combination organic mask formulation from Moringa leaves and turmeric and test its effectiveness. This experimental study, which had a one-shot case study design, was conducted at the Pharmaceutical Technology Laboratory and Phytochemical Laboratory, Pharmacy Department, Health Polytechnic, Ministry of Health, Jambi. The formulation consisted of Moringa leaf powder and turmeric with formulas F1 (40%, 30%), F2 (50%, 25%) and F3 (60%, 20%). Further data analysis used the paired t-test. The evaluation consists of phytochemical screening, characteristic tests of the organic mask (organoleptic, pH, drying time, and homogeneity), stability tests (organoleptic, fungal growth), effectiveness tests of mask preparations (skin moisture), and antioxidant activity tests. Based on the results, formula 3 showed the best results as an organic mask preparation with moisture test results of 58.87 ± 6.24 (mean ± SD), p <0.001. The antioxidant activity results showed IC50 values of each formula were F1 (73.43 µg/ml), F2 (56.33 µg/ml), and F3 (182.11 µg/ml). This study recommends that Moringa leaves and turmeric have potential and effectiveness as antioxidant compounds that can be developed as organic mask preparations.
Socioeconomic and Clinical Profile of Diabetic Foot Ulcer Patients with National Health Insurance during Pandemic COVID-19 in Indonesia Fitrianingsih, Fitrianingsih; Sauriasari, Rani; Yunir, Em; Banun Saptaningsih, Agusdini
Jurnal Kefarmasian Indonesia VOLUME 15, NUMBER 1, FEBRUARY 2025
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

During the COVID-19 pandemic, the mandatory lockdown and government policy in prioritizing COVID-19 patients affected patients with diabetic foot ulcers (DFU). Most DFU patients experienced difficulties visiting hospitals and covering the cost of treatment, which led to changes in patient characteristics, poor clinical outcomes, and higher total costs. This study aimed to determine the sociodemographic and clinical outcomes profile of DFU patients under National Health Insurance (NHI-DFU) during the COVID-19 pandemic and their effect on the total direct medical cost. This cross-sectional study enrolled all JKN-DFU hospitalized patients at the National Referral Hospital, Cipto Mangunkusumo Hospital (RSCM), Jakarta, Indonesia, during COVID-19 pandemic (March 2nd, 2020, to December 2022). We used electronic health records, electronic billing, and foot registry systems. Participants were over 18 years old in a single admission period. Statistical analysis used Mann-Whitney and Kruskal-Wallis; Post hoc used the Mann-Whitney test. There were 158 JKN-DFU patients with predominated criteria: female patients (55.1%), aged over 60 years old (55.1%) with a mean age of 59.3 ± 11.0 years, unemployed (63.9%), intermediate educated (41.8%), Jakarta residents (68.4%), and mostly severe infection (63.3%). The total cost was much higher than INA-CBG’s coverage. The occupation (p=0.048), length of stay (LOS) (p=0.001), and amputation status (p<0.001) significantly affected total cost. Civil servants, longer LOS, and major amputation status leading higher total costs.
Pengaruh Edukasi Farmasi Meningkatkan Literasi Siswa Tentang Vape, Obat ilegal, dan Ketepatan dalam Penggunaan Obat Psikotropika Yuliawati; Sadli, Nurul; Amalia Nasution, Riska; Sani K, Fathnur; Lestari, Uce; Andriani, Annisa; Syamsurizal; Fitrianingsih
Jurnal Pengabdian Harapan Ibu (JPHI) Vol. 7 No. 3 (2025): Jurnal Pengabdian Harapan Ibu (JPHI)
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/jphi.v7i3.1113

Abstract

Meningkatnya prevalensi gangguan kesehatan mental memerlukan intervensi yang sistematis, salah satunya melalui peningkatan literasi kesehatan mental pada populasi remaja. Tingkat literasi rendahnya cenderung menangani masalah mental ke praktik-praktik berisiko, termasuk menganggapan keliru bahwa rokok elektrik lebih aman daripada rokok konvensional padahal sejumlah zat terlarang seperti etomidate, metomidate, dan ketamin dilaporkan dapat ditemukan pada beberapa produk cairan rokok elektrik serta penggunaan psikotropika yang tidak tepat bahkan meningkatkan kondisi psikologis. Untuk itu dilakukan intervensi edukatif pada siswa MAN 1 Kota Jambi menggunakan kombinasi ceramah, diskusi aktif, dan materi audiovisual untuk meningkatkan pemahaman dan keterampilan pencegahan. Evaluasi efektivitas program dilakukan dengan instrumen pre-test dan post-test berbasis Google Form , hasilnya menunjukkan peningkatan skor rata-rata pengetahuan dari 55,12 menjadi 80,48, disertai respon antusias dari peserta terhadap representasi materi. Temuan ini menunjukkan bahwa pendekatan terpadu berbasis partisipasi aktif mampu meningkatkan literasi dan kesiapan remaja dalam mencegah serta mengelola gangguan kesehatan mental. Namun, keinginan dan dampak intervensi memerlukan langkah lanjutan berupa kolaborasi berkelanjutan antara institusi pendidikan dan layanan kesehatan.
Effects of Biofertilizer Application and Organic Matter Incubation on Soil Chemical Properties Aisyah; Asnur, Paranita; Fitrianingsih; Risnawati
Jurnal Penelitian Pendidikan IPA Vol 11 No 11 (2025): November: In Progress
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i11.13342

Abstract

Soil organic matter is essential for maintaining soil fertility and supporting sustainable agricultural production. However, raw organic matter does not directly enhance soil chemical properties without a sufficient decomposition period. This study evaluated the effects of organic matter incubation and biofertilizer concentrations on soil chemical characteristics. The experiment was conducted from June to August 2024 in the Greenhouse Laboratory of Gunadarma Technopark University, Jamali Village, West Java, using a completely randomized factorial design. Treatments consisted of four biofertilizer concentrations (0, 10, 15, and 20 mL/L) and five incubation periods of cow manure (0, 1, 2, 3, and 4 weeks), each replicated four times, resulting in 80 experimental units. The results showed a significant interaction between incubation duration and biofertilizer concentration on soil pH, organic carbon, total nitrogen, C/N ratio, available phosphorus (P₂O₅), and available potassium (K₂O). The four-week incubation combined with 10–20 mL/L of biofertilizer produced the most notable improvements, increasing pH to neutral levels, raising organic carbon and nitrogen contents, achieving an optimal C/N ratio, and enhancing P availability, although K remained low. These findings indicate that combining biofertilizer application with an adequate incubation period effectively improves soil fertility and offers a viable strategy for long-term soil management and agricultural productivity.
DIVERSIFICATION OF HERBAL PRODUCTS BASED ON LOCAL WISDOM AS AN EFFORT TO PREVENT STUNTING FOR THE COMMUNITY OF OLAK KEMANG VILLAGE Kasmadi, Fathnur Sani; Maharini, Indri; Maimum, Maimum; Fitrianingsih, Fitrianingsih; Neldi, Vina; Astuti, Novia Tri; Perawati, Santi; Yuliawati, Yuliawati; Yuliandani, Yuliandani; Nurfadilah, Nurfadilah
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 2 (2025): MEDIC. Medical dedication (In Progress)
Publisher : Universitas Jambi

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Abstract

Stunting, or chronic malnutrition, remains a significant public health challenge in Indonesia, impacting the cognitive and physical development of children. This community service project aimed to address this issue through a culturally sensitive and sustainable approach in the community of Olak Kemang Village, Jambi. The program focused on diversifying local wisdom-based herbal products to improve nutritional intake among pregnant women, lactating mothers, and children under five. The method involved a three-stage process: (1) socialization and nutritional education about stunting, (2) training on the hygienic processing of local plants rich in micronutrients, such as Moringa (Moringa oleifera) and Katuk leaves (Sauropus androgynus), and (3) a hands-on workshop on creating diversified, child-friendly products like herbal powders, fortified cookies, and puddings. Pre- and post-activity questionnaires demonstrated a significant increase in participants' knowledge and awareness of stunting prevention, from 67,4% to 90,58%. Participants also successfully produced several innovative herbal food products. This initiative highlights that empowering communities by integrating local knowledge with scientific principles is a promising and effective strategy for stunting prevention. Keywords: Stunting, community service, herbal product, nutrition, local wisdom.
KAJIAN INTERAKSI OBAT BERDASARKAN KATEGORI SIGNIFIKANSI KLINIS TERHADAP POLA PERESEPAN PASIEN RAWAT JALAN DI APOTEK X JAMBI Agustin, Ovi Amelia; Fitrianingsih, Fitrianingsih
Scientific Of Environmental Health and Diseases Vol. 1 No. 1 (2021): Scientific of Envitonmental Health And Diseases
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (151.901 KB) | DOI: 10.22437/esehad.v1i1.10759

Abstract

ABSTRACT One of the problem that caused by in patient prescription pattern which can affect the outcome is drug interactions. Drug interactions is a condition that occur when a drug is altered by the effect of other drugs, food or beverages. Drug interaction can cause a reduction of therapeutic, increasing of toxicity or pharmacological activity that is not expected. Based on the level of clinical significance, drug interactions are classified into three : major, moderate and minor. This research was aimed to determine the potency of drug interaction based on clinical significance of the patient’s prescription at the drug store of X Jambi, then to identified the effect and know to treat them well. This was a cohort prospective method with observe and study the prescriptions for a potentially interaction of drugs. Data analyses were descriptive by knowing the potential drug interactions using Medscape applications. 30 prescriptions have potential drug interactions of all 250 prescriptions with 48 interactions of the drug component. The largest percentage 57.44% potential drug interactions followed by minor drug interactions with 36.17% then 6.38% mayor potential interactions. The role of pharmacist is principally about the side effect of drugs and drug interactions when the patients take two or more drugs at the same time. Keywords : drug interactions, clinical significance, presciptions, drug store. ABSTRAK Salah satu masalah yang ditimbulkan dalam pola peresepan pasien yang dapat mempengaruhi outcome klinis pasien adalah interaksi obat. Interaksi obat merupakan interaksi yang dapat terjadi apabila efek obat diubah oleh obat lain, makanan, atau minuman. Dampak yang mungkin terjadi jika terdapat potensi interaksi obat antara lain adalah penurunan efek terapi, peningkatan toksisitas, atau efek farmakologis yang tidak diharapkan. Berdasarkan level signifikansi klinis, interaksi obat diklasifikasikan menjadi tiga yaitu mayor, moderate dan minor. Penelitian ini bertujuan untuk mengidentifikasi potensi interaksi obat berdasarkan level signifikansi klinis terhadap pola peresepan pasien rawat jalan di Apotek X Jambi, mengetahui dampak yang mungkin terjadi serta mengetahui bagaimana cara penanganannya. Metode penelitian yang digunakan cohort prospektif dengan melakukan pengamatan serta pengkajian terhadap resep yang berpotensi terjadi interaksi obat. Analisa data dilakukan secara deskriptif dengan mengetahui gambaran potensi interaksi obat menggunakan aplikasi Medscape. Total dari 250 resep terdapat 30 resep mengalami interaksi dengan 48 kejadian interaksi. Persentase terbesar ditunjukkan dari potensi interaksi obat yang tergolong dalam kategori moderate sebesar 57,44% diikuti dengan potensi interaksi minor sebesar 36,17% dan mayor sebesar 6,38%. Diperlukannya peran seorang farmasis terutama mengenai efek samping dan interaksi obat yang dapat terjadi ketika pasien menggunakan dua buah obat atau lebih dalam waktu yang bersamaan. Kata Kunci: Interaksi obat, signifikansi klinis, resep, Apotek.