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All Journal MEDISAINS KOVALEN: Jurnal Riset Kimia CHEMPUBLISH JOURNAL Lantanida Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) As-syifaa Jurnal Farmasi Pharmasipha Jurnal Farmasi Higea Health Sciences and Pharmacy Journal INTEGRITAS : Jurnal Pengabdian Jurnal ABDINUS : Jurnal Pengabdian Nusantara Jurnal Inovasi Farmasi Indonesia Medicra (Journal of Medical Laboratory Science/Technology) Prosiding Conference on Research and Community Services MAHESA : Malahayati Health Student Journal Environmental and Toxicology Management (ETM) CHEDS: Journal of Chemistry, Education, and Science Jurnal Pengabdian Sosial Lestari: Jurnal Pengabdian Kepada Masyarakat JI-KES (Jurnal Ilmu Kesehatan)
Ngibad, Khoirul
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Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Program Pendampingan Cara Pemilihan Produk Skincare Aman Untuk Kulit Sehat Bagi Ibu-Ibu Paruh Baya Di Desa Krebet Kecamatan Srengat Muadifah, Afidatul; Ngibad, Khoirul
Jurnal ABDINUS : Jurnal Pengabdian Nusantara Vol 5 No 1 (2021): Volume 5 Nomor 1 Tahun 2021
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/ja.v5i1.15311

Abstract

The purpose of this community service is to increase knowledge on the skin health of middle-aged mothers in Krebet Village, Srengat District through a mentoring program for the use of safe skincare. The methods used are (1) observation and interviews; (2) Learning; (3) Assistance; and (4) Evaluation. Results: Middle-aged mothers who have used various types of skincare products obtained from doctor's clinics and cosmetic stores are 24 people. The results of learning on middle-aged mothers in Krebet Village, Srengat District of the qualitative test method and the dangers of mercury and hydroquinone in skincare products show a good value. with a percentage increase in knowledge of 67%. The results of assistance to middle-aged mothers in Krebet Village, Srengat District in stopping the use of positive skincare containing mercury and hydroquinone through replacement with skincare products that are safe for healthy skin shows good results with a 75% increase in skills so that the quality of health is better maintained.
Aktivitas antibakteri formulasi obat kumur daun salam dan cengkeh terhadap S. aureus periodontitis Sari, Yuke Pramudita; Amanda, Lyrra Mirna; Maulana, Nabilah Rosdiana; Wijayanti, Cicik; Abraham, Ali; Ngibad, Khoirul
Health Sciences and Pharmacy Journal Vol. 9 No. 3 (2025)
Publisher : STIKes Surya Global Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32504/hspj.v9i3.1287

Abstract

Kesehatan dan kebersihan rongga mulut harus dijaga karena terdapat mikroflora normal, namun akan menjadi patogen sehingga menyebabkan peradangan, nekrosis, dan pembentukan abses. Staphylococcus aureus merupakan penyebab paling umum. Akumulasi sisa makanan terus menempel dan bertumpuk akan menimbulkan plak yang dapat menyebabkan periodontitis. Tujuan penelitian ini adalah untuk menentukan formulasi terbaik campuran ekstrak daun salam dan Minyak Cengkeh sebagai obat kumur herbal dalam menghambat pertumbuhan Staphylococcus aureus. Metode penelitian ini dengan melakukan maserasi daun salam menggunakan etanol 96%, kemudian dievaporasi untuk mendapatkan ekstrak kental. Obat kumur diformulasi menjadi tiga: formulasi I (1 g ekstrak daun salam / 5 ml minyak cengkeh, formulasi II (2 g / 7,5 ml), dan formulasi III (3 / 10 ml). Kemudian dilanjut dengan evaluasi sediaan obat kumur, yaitu: uji organoleptis, pH, viskositas, homogenitas, stabilitas. Terakhir, dilakukan uji antibakteri data di analisis menggunakan uji One Way ANOVA dan Post Hoc Test (Tukey). Hasil evaluasi sediaan didapatkan rentan nilai yang sesuai standar pada uji organoleptis, homogenitas, stabilitas, dan pH. Hasil uji viskositas didapatkan kekentalan sangat tinggi. Formulasi II merupakan formulasi terbaik yang menghasilkan zona hambat tertinggi terhadap bakteri Staphylococcus aureus (12,9 mm). Uji ANOVA menunjukkan bahwa tidak ada perbedaan yang signifikan diantara ketiga formulasi (sig >0,05). Hasil uji Post Hoc Test metode Tukey didapatkan perbedaan secara nyata pada masing-masing bahan dengan formulasi obat kumur (sig < 0,05). Formulasi II merupakan formulasi terbaik yang dapat digunakan sebagai alternatif obat kumur terhadap penyakit periodontitis.
Sub-acute toxicity evaluation of Ziziphus spina-christi and Adenanthera pavonina leaf extracts combination in rats: an in vivo study Ngibad, Khoirul; Ayu , Patricia Gaby; Fafa , Angelica Rosia; Tria , Novitasari; Farichatul , Wachda
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Vol. 23 No. 3 (2025)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v23i3.27311

Abstract

Background: The safety of combined herbal extracts remains underexplored, particularly for Ziziphus spina-christi and Adenanthera pavonina, which contain bioactive compounds with potential toxic effects. Objective: To evaluate the sub-acute toxicity of combined leaf extracts on hematological, biochemical, and organ morphology parameters in Wistar rats. Method: Thirty male and female rats were randomized into five groups receiving vehicle control or extract doses of 4000, 8000, and 10,000 mg/kg BW for 21 days following OECD 407. Blood hematology, renal biomarkers, bilirubin levels, organ weight, and morphology were analyzed. Results: Mortality increased dose-dependently, reaching 20% in males and 10% in females at 10,000 mg/kg BW. Hematology and renal biomarkers showed no significant differences (p>0.05). Total bilirubin increased at the highest dose. Morphological abnormalities, including pale discoloration and dark foci, were observed in liver and kidneys at higher doses. Conclusion: The combination extract is safe up to 8000 mg/kg BW, while 10,000 mg/kg BW induces organ alterations and increased mortality.
Co-Authors Adhiba, Eka Indira Afidatul Muadifah Aldimas, Reven Ali Abraham, Ali Amanda, Lyrra Mirna Andriansyah, Firman Angge, Bagas Anton Sumarpo Ardiansah, Prianggara Arif Santoso Arif, Donny Arnando, Rasi Andante Arrafi, David Khalik As Syukri, Khoirul Anam Aulia, Rizza Fatma Ayu , Patricia Gaby Basyori, Imam Caesaria, Vica Ayu Candra Aldiansyah, Rio Chaniroh, St. Lutfi Choifin, Mochamad Cholik, Dimas Satria Nur Damayanti, Alvina Datin An Nisa Sukmawati Dianto, Annando Kusuma Dony Perdana Efawati, Susi Fafa , Angelica Rosia Fahrudin, Ahmad Dani Farichatul , Wachda Farkhan, M. Farkhan, Muhammad Galuh Puspita Sari Indra Lasmana Tarigan Islami, Putri Nova Nur Jannah Triarini, Lailatul Jannah, Elok Faiqotul Karel Damayanti, Novita Kholifah, Siti Nurriyatul Kristijono, Ary Laila Fitria Lilla Puji Lestari LINGGAWAN, STEPHANI Lukman Hakim Margalin, Brilliant Maulana, Nabilah Rosdiana Melinda, Selvina Dwi Merlina, Diana Mey Miftahul Jannah Miftakhul Huda Muadifah , Afidatul Muadifah, Afidatul Muhammad Aziz Muzakiyah, Nur Aini NURUL AZIZAH Pratama, Agung Firman Priambodo, Sigit Putra, Bayu Charisma Putri, Intan Syahrani RAHARJO, BUDIONO Rahma Diyan Martha Rahmatullah, Ilham Ramadani, Ade Ramadhina, Amanda Putri Ramadhini, Ananda Putri Rini, Yenny Puspa Rivaldo, M Ario Rizki Amalia, Laily Rodli, Achmad Fathoni Rosidin, Mochammad Khoirul Salsabila, Nabila Putri Saputra, Ahmad Bayu Saputra, Ifan Dwi Sari, Renny Nirwana Sari, Yuke Pramudita Sembilu, Nambi Setiawan Setiawan Sowe, Momodou Salieu Sukmawati , Datin An Nisa Sungging Pradana, Muhammad Tilarso, Dara Pranidya Tria , Novitasari Valenata, Valenata Wahyu Ningtias, Titis Wijayanti, Cicik Winarti, Siti Sri WULAN PURNAMASARI, WULAN Yanto, Fauzan Tri Yucha, Nikma Yuliantari, Sonia Devi Yusmiati, Siti Nur Husnul