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Journal : CHEMPUBLISH JOURNAL

PENGARUH METODE MASERASI DAN SOKHLASI TERHADAP KANDUNGAN SENYAWA ANTIOKSIDAN DAUN Pluchea indica L. DENGAN METODE LC-MS Afidatul Muadifah; Tilarso, Dara Pranidya; Sowe, Momodou Salieu; Tarigan, Indra Lasmana; Ngibad, Khoirul; Yuliantari, Sonia Devi
Chempublish Journal Vol. 8 No. 2 (2024): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v8i2.36869

Abstract

Pluchea indica L. is a plant have some secondary metabolite compounds namely flavonoids, alkaloids, tannins, saponins, terpenoids, and phenols that have antioxidants activity. The purpose of this study was to compare the content of antioxidant compounds analyzed using LC-MS and determine the relationship of antioxidant activity through the DPPH test on P. indica leaves extracted by maceration and soxhlation. The extracts from maceration and soxhlation of P. indica leaves were analyzed using LC-MS to determine the composition of the compounds contained therein then continued with the antioxidant activity test using the DPPH method. In the antioxidant activity test using DPPH, each extract was made 3 variations of concentration, namely 10 ppm, 50 ppm, and 100 ppm, and measured based on the absorbance of DPPH at a wavelength of 515 nm using a UV-vis spectrometer. The results of analysis using LC-MS on macerated extracts of P. indica leaves are 112 compounds consisting of flavonoids 72.4841%, phenols 9.00625%, terpenoids 6.11827%, alkaloids 6.99075%, tannins 2.2256%, and saponins 2.04458%. The Soxhlet extraction contained 116 compounds consisting of flavonoids 67.14345%, phenols 8.95854%, terpenoids 13.82165%, alkaloids 5.35637%, tannins 2.53305%, and saponins 0.2969%. The results of the antioxidant activity test using DPPH on maceration extracts have an IC50 value of 76.7576 and soxhlation 62.580 ppm. Both maceration and soxhlation extracts of P. indica leaves contain compounds that have high antioxidant potential and have good antioxidant activity, namely in the strong antioxidant category. However, the soxhlation extract has more compounds and a lower IC50 value. Thus, the more antioxidant compounds contained in an extract, the lower the IC50 value so that the better the antioxidant activity.
Calcium Reduction Using Variations of Thickness and Retention Time of Cocoa Shell Activated Carbon Muadifah, Afidatul; Santoso, Arif; Ngibad, Khoirul; Martha, Rahma Diyan; Kholifah, Siti Nurriyatul
Chempublish Journal Vol. 7 No. 1 (2023): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v7i1.24768

Abstract

High levels of hardness can lead to increased cases of kidney stones. Hardness levels can be reduced by using activated carbon from the cocoa rind as an adsorbent. The purpose of this research was to determine the variation of activated carbon thickness and optimum retention time in reducing the calcium content of dug well water, to determine the percent decrease in calcium ion levels at the optimum variation, and to determine the significance of the difference in the decreased in calcium levels between the treatment groups. The research method used the principle of adsorption of activated carbon from cocoa shells to calcium ions, which are activated by KOH. There were ten treatment samples with different variations of activated carbon thickness and retention time. The results showed that the thickness of activated carbon of 60 cm with a retention time of 50 minutes had the optimum ability to reduce the calcium content of dug well water. The percentage decrease in calcium levels reached 89,041 % with a decreased concentration of 234 ppm. The result of the statistical test showed a significance value of 0,05. The conclusion of the research is that activated carbon of cocoa shells can reduce calcium levels to the levels of soft water hardness, with variations in activated carbon thickness and retention time having a significant effect.
Co-Authors Adhiba, Eka Indira Afidatul Muadifah Aldimas, Reven Ali Abraham, Ali Amanda, Lyrra Mirna Andriansyah, Firman Angge, Bagas Anton Sumarpo Ardiansah, Prianggara Arif Santoso Arif, Donny Arnando, Rasi Andante Arrafi, David Khalik As Syukri, Khoirul Anam Aulia, Rizza Fatma Basyori, Imam Caesaria, Vica Ayu Candra Aldiansyah, Rio Chaniroh, St. Lutfi Choifin, Mochamad Cholik, Dimas Satria Nur Damayanti, Alvina Datin An Nisa Sukmawati Dianto, Annando Kusuma Dony Perdana Efawati, Susi Fadhila, Nurisma Fahrudin, Ahmad Dani Farkhan, M. Farkhan, Muhammad Fernanda, Sofia Ayu Firdania Firdaus Rosyida Galuh Puspita Sari Indra Lasmana Tarigan Islami, Putri Nova Nur Jannah Triarini, Lailatul Jannah, Elok Faiqotul Karel Damayanti, Novita Khairil Anam, Khairil Kholifah, Siti Nurriyatul Kisdiati, Putri Yoggy Mayssa Kristijono, Ary Laila Fitria Lilla Puji Lestari LINGGAWAN, STEPHANI Lukman Hakim Margalin, Brilliant Maulana, Nabilah Rosdiana Melinda, Selvina Dwi Merlina, Diana Mey Miftahul Jannah Miftakhul Huda Muadifah , Afidatul Muadifah, Afidatul Muhammad Aziz Mukarromah, Tarisatus Syahlum Munandar, David Khalik Arrafi Muzakiyah, Nur Aini Nuardani, Hanifah Delima NURUL AZIZAH Nuryani, Elis Dwi Oktaviani, Galuh Anggun Patricia, Gaby Ayu Pradana, Muhammad Sungging Pratama, Agung Firman Priambodo, Sigit Putra, Bayu Charisma Putri, Intan Syahrani RAHARJO, BUDIONO Rahma Diyan Martha Rahmatullah, Ilham Ramadani, Ade Ramadhina, Amanda Putri Ramadhini, Ananda Putri Rifqiyah, Jazilatur Rini, Yenny Puspa Rivaldo, M Ario Rizki Amalia, Laily Rodli, Achmad Fathoni Rosidin, Mochammad Khoirul Salsabila, Nabila Putri Saputra, Ahmad Bayu Saputra, Ifan Dwi Sari, Renny Nirwana Sari, Yuke Pramudita Savitri , Lisa Sembilu, Nambi Setiawan Setiawan Sowe, Momodou Salieu Sukmawati , Datin An Nisa Sungging Pradana, Muhammad Tilarso, Dara Pranidya Valenata, Valenata Wahyu Ningtias, Titis Wijayanti, Cicik Winarti, Siti Sri WULAN PURNAMASARI, WULAN Yanto, Fauzan Tri Yucha, Nikma Yuliantari, Sonia Devi Yusmiati, Siti Nur Husnul