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Perbandingan Penanda Inflamasi dan Elastisitas Vaskular antara Mahasiswa Kedokteran Prehipertensi dan Normotensi di Jakarta Wibowo, Naufal Rafi Kusuma; Bustamam, Nurfitri; Bahar, Meiskha; Purwaningastuti, Diana Agustini
Jurnal Kedokteran Meditek Vol 31 No 2 (2025): MARCH
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i2.3539

Abstract

Introduction: An unhealthy lifestyle among medical students maycontribute to inflammation, reduced vascular elasticity, andincreased blood pressure. However, cardiovascular risk in theseyoung adults remains less explored compared to hypertensivepatients. Purpose: This study compares inflammatory markers andvascular elasticity in prehypertensive and normotensive medicalstudents. Methods: A case-control study utilizing simple randomsampling was conducted in the medical student population, included54 prehypertensive or normotensive subjects with no history ofhematological disorders, autoimmune diseases, cancer, diabetesmellitus, or cardiovascular medication use. Vascular elasticity,blood pressure, and inflammatory markers were assessed using anaccelerated photoplethysmograph, a digital sphygmomanometer,and a hematology analyzer. Results: A total of 25 subjects (46.3 %)had suboptimal vascular elasticity, 30 (55.6%) had a highneutrophil-to-lymphocyte ratio (NLR), and 40 (74.1%) exhibited alow-risk platelet-to-lymphocyte ratio (PLR). The Chi-square testrevealed a significant difference in NLR between prehypertensiveand normotensive students (p = 0.000; OR = 7.0; CI = 2.3–20.7),while no significant difference was observed in PLR (p = 0.525).Vascular elasticity also differed significantly between groups (p =0.000; OR = 5.2; CI = 2.0-13.2). Conclusion: Prehypertensivesubjects had higher NLR, and those with suboptimal vascularelasticity had higher prehypertension risk. These findings highlightthe need for cardiovascular risk assessment in young adults.
Pengembangan UMKM ‘Inovasi Olahan Lele’ di Desa Sukadami Cikarang Selatan dengan Modernisasi Kemasan dan Pemanfaatan Teknologi Digital Zuchriadi, Achmad; WIdyanto, Didit; Bustamam, Nurfitri; Ladesvita, Fiora; Darmawan, Mutiara
Lebah Vol. 18 No. 3 (2025): May: Pengabdian
Publisher : IHSA Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/lebah.v18i3.313

Abstract

Pengabdian Masyarakat ini dilakukan di Desa Sukadami Kecamatan Cikarang Selatan dengan mitra UMKM Inovasi Olahan Lele pimpinan Ibu Asmanidar. Permasalahan yang dihadapi dari masih belum optimalnya penjualan diantaranya, yaitu: (1) Kemasan produk masih tradisional, (2) pada kemasan belum dicantumkan kandungan gizi, (3) proses pemasaran masih dilakukan secara tradisional. Tujuan dari PKM-T ini, yaitu mengakselerasi Perkembangan Penjualan UMKM Inovasi Olahan Lele dengan memperbaiki kemasan, memasukan kandungan gizi pada kemasan, diversifikasi produk dalam bentuk frozen olahan lele agar mudah dijual secara online menggunakan teknologi digital terkini. Kegiatan ini berhasil dilaksanakan dalam bentuk workshop dan pendampingan yang dihadiri UMKM olahan lele dan anggota Forum UMKM Cikarang Selatan serta didukung penuh oleh Pimpinan Kecamatan Cikarang selatan
Association between muscle-to-visceral fat ratio and vascular elasticity in medical students Ayudia, Tsabita; Bustamam, Nurfitri; Harjono Hadiwiardjo, Yanti; Agustini Purwaningastuti, Diana
World Nutrition Journal Vol. 9 No. i1 (2025): Volume 09 Issue 1, August 2025
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V09.i1.0005

Abstract

Background: Medical students often adopt lifestyles that contribute to decreased muscle mass and increased visceral fat accumulation, which can negatively impact vascular elasticity, a biomarker for the early detection of cardiovascular disease. Objective: This study aims to evaluate the association between the muscle mass to visceral fat ratio and vascular elasticity in medical students at Universitas Pembangunan Nasional Veteran Jakarta (UPNVJ). Methods: A cross-sectional design was conducted from November 2023 to January 2024 at UPNVJ. The sample consisted of 51 subjects who met the research criteria. The muscle-to-visceral fat (MVF) ratio was measured using Bioelectrical Impedance Analysis (BIA), while vascular elasticity was assessed using the Accelerated Photo plethysmograph Analyzer SA-3000P. Results: The results revealed that 68.6% of the subjects had the lowest MVF ratio and 54.9% exhibited sub-optimal vascular elasticity. No differences were found in age, gender, physical activity, or eating habits between the vascular elasticity groups (p > 0.05). The Chi-square test revealed a significant association between the MVF ratio and vascular elasticity (p = 0.009; OR = 6.545; 95% CI = 1.7–24.9). Conclusion: Students with the lowest MVF ratio were found to be 6.54 times more likely to have sub-optimal vascular elasticity, compared to those with low and high MVF ratios, indicating an increased risk of cardiovascular disease. These findings underscore the importance of early preventive intervention aimed at optimizing body composition through targeted wellness programs. The implementation of nutritional education and structured physical activity initiatives, particularly in young adults, may play a critical role in reducing the risk of cardiovascular disease.
The Relationship between Prediabetes and Prehypertension with Vascular Elasticity in Medical Students Pangaribuan, Kia Iglesias; Bustamam, Nurfitri; Chairani, Aulia; Dewiastuti, Marlina
JURNAL INFO KESEHATAN Vol 23 No 3 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss3.1884

Abstract

Prediabetes and prehypertension are known to affect vascular elasticity, and the prevalence of these conditions among young adults is increasing. This study examines the relationship between prediabetes and prehypertension with vascular elasticity in medical students. The study utilized a cross-sectional design and the technique of simple random sampling, involving a total of 69 students. The research subjects' criteria were medical students aged 18–25 years who were non-smokers, did not consume alcohol, had no history of diabetes or hypertension, and were not taking medications affecting blood pressure or blood glucose levels. Vascular elasticity, blood pressure, and fasting blood glucose levels were measured using an Accelerated Photoplethysmograph Analyzer SA-3000P, a digital sphygmomanometer, and a glucometer, respectively. The findings indicated no differences in gender, BMI, age, and physical activity between the suboptimal vascular elasticity and the normal+optimal elasticity groups (p > 0.05). The Chi-square test identified significant differences in vascular elasticity between the prediabetes and normal groups (p = 0.009; PR = 1.6; CI = 1.1–2.2), the prehypertension and normal groups (p = 0.026; PR = 1.5; CI = 1.1–2.2), and the prediabetes+prehypertension and normal groups (p = 0.002; PR = 3.5; CI = 1.4–8.3). These findings indicate that prediabetes, prehypertension, or both conditions are associated with reduced vascular elasticity.
Pemberdayaan Masyarakat dalam Mengendalikan Tekanan Darah di Posbindu Delima, Sawangan Depok: Community Empowerment in Controlling Blood Pressure at Posbindu Delima, Sawangan Depok Bustamam, Nurfitri; Hardini, Niniek; Fauziah, Cut
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 12 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i12.8317

Abstract

In 2023, data from Posbindu Delima, Sawangan Depok, showed that 37 residents had blood pressure ≥140/90 mmHg (hypertension), and 5 residents had already experienced complications from hypertension, such as stroke and heart disease. In response to this issue, a community service was conducted to help control the blood pressure of residents with hypertension by adopting a healthy lifestyle. The community service consists of three stages: disseminating guidelines for filling out the healthy lifestyle logbook and socializing the community service program, providing direct education and education using WhatsApp, and evaluating. The knowledge level, medication adherence, and health of residents with hypertension were measured before and after community service. The evaluation of healthy lifestyle implementation was based on logbook data. The 5-week community service was attended by 12 residents, most of whom (66.7%) were female with an average age of 60.6 ± 8.6 years. The community service results showed the knowledge level of residents increased significantly, but there was no statistical difference in medication adherence. After adopting a healthy lifestyle, there were significant health improvements, including increased residents with controlled blood pressure, weight loss, and reduced waist circumference. It can be inferred that the community service successfully increased knowledge and encouraged residents with hypertension to adopt a healthy lifestyle, resulting in controlled blood pressure.
Korelasi antara Massa Otot dan Fungsi Kognitif pada Mahasiswi Kedokteran Fazriani, Alifianisa; Bustamam, Nurfitri; Tjang, Yanto Sandy; Heristyorini, Ayodya
Jurnal Kedokteran Meditek Vol 29 No 3 (2023): SEPTEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v29i3.2846

Abstract

Hasil penelitian tahun 2018 menunjukkan sebanyak 52,5% dari 217 mahasiswa kedokteran melakukan sedentary lifestyle. Sedentary lifestyle dapat mengakibatkan berkurangnya massa otot sehingga terjadi perubahan sintesis miokin yang memberikan dampak merugikan pada fungsi kognitif. Penelitian ini bertujuan untuk mengetahui korelasi antara massa otot dan fungsi kognitif pada mahasiswi kedokteran. Penelitian menggunakan desain dengan besar sampel 90 mahasiswi yang diambil seluruhnya (total sampling) dari mahasiswa sesuai kriteria penelitian. Instrumen penelitian yang digunakan adalah Tanita Medical Body Composition Analyzer (MC-980MA Plus) dan kuesioner Digit Symbol Substitution Test (DSST). Hasil penelitian didapatkan 38 (42,2%) subjek memiliki massa otot rendah, 47 (52,2%) subjek memiliki massa otot normal, dan 5 (5,6%) subjek memiliki massa otot tinggi. Hasil pemeriksaan fungsi kognitif didapatkan skor dengan median 61 (43-76), 64 (50-100), dan 81 (68-92) berturut-turut pada kelompok massa otot rendah, normal, dan tinggi. Hasil uji Kruskal-Wallis menunjukkan perbedaan skor fungsi kognitif antar kelompok massa otot (p = 0,023). Hasil uji Spearman menunjukkan korelasi antara massa otot dan skor fungsi kognitif dengan korelasi lemah (p = 0,008; r = 0,279). Semakin tinggi massa otot, semakin baik fungsi kognitif.
Association of Muscle Mass and Fasting Blood Glucose with Vascular Elasticity in Medical Students Purba, Raja Soaloon; Bustamam, Nurfitri; Thadeus, Maria Selvester; Dewiastuti, Marlina
Jurnal Ilmiah Kesehatan Masyarakat : Media Komunikasi Komunitas Kesehatan Masyarakat Vol 17 No 4 (2025): JIKM Vol 17, Issue 4, November 2025
Publisher : Public Health Undergraduate Program, Faculty of Health Science, Universitas Pembangunan Nasional Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Low vascular elasticity is one of the key determinants of cardiovascular disease risk. Sedentary lifestyles and high-glucose diets may decrease muscle mass and increase blood glucose levels, potentially reducing vascular elasticity. This study aimed to analyze the relationships among muscle mass, fasting blood glucose levels, and vascular elasticity in medical students. Methods: A cross-sectional study was conducted involving 53 medical students aged 18—22 years using a stratified random sampling technique. Eligible participants were non-smokers, non-alcohol consumers, and had no history of diabetes, hypertension, or the use of medications affecting blood pressure, blood glucose, or cholesterol levels. Muscle mass, fasting blood glucose, and vascular elasticity were measured using a bioelectrical impedance analyzer, capillary blood testing, and an accelerated photoplethysmograph, respectively. Data were analyzed using a Chi-square tests and multivariable Logistic Regression. Results: There were no significant differences in age, blood pressure, BMI, or eating habits between the suboptimal and normal/optimal vascular elasticity groups (p > 0.05). Multivariable analysis showed that muscle mass was significantly associated with vascular elasticity (p = 0.009; OR = 9.656; CI = 1.757–53.075), after adjustment for fasting blood glucose levels (p = 0.386; OR = 2.329; CI = 0.344–15.776). Participants with higher muscle mass were nearly 10 times more likely to have better vascular elasticity. Conclusion: Muscle mass is significantly associated with vascular elasticity in young adults, independent of fasting blood glucose levels. These findings highlight the importance of maintaining adequate muscle mass. Promoting muscle mass through healthy lifestyle habits may help preserve vascular elasticity and reduce the risk of cardiovascular disease.
Co-Authors Abd. Rasyid Syamsuri Abimanyu Putera Yudha Achmad Zuchriadi Agneta Irmarahayu Agustini Purwaningastuti, Diana Andrisha, Naufal Hilmi Astari, Riezky Valentina Aulia Chairani Aulia Chairani, Aulia Auliannissa, Salma Ayodya Heristyorini Ayudia, Tsabita Azzahra Brenda Tam Basuki Supartono Budiman, Anisa Novita Citra Ayu Aprilia Citra Ayu Aprilia Citra Ayu Aprilia Cut Fauziah Cut Fauziah Cut Fauziah Cut Fauziah Darmawan, Mutiara Dewi, Via Arsita Dhia Adhi Perwirawati Diana Agustini Purwaningastuti Diana Agustini Purwaningastuti Duma Lumban Tobing Eko Satrio Bahari Eko Satrio Bahari Erna Harfiani Evin Novianti Fahira Alia Natassha Fajriati Zulfa Fatma M Idrus Baagil Fazriani, Alifianisa Fellicia Naurah Andryas Ferrany Thifla Aghni Brilliana Fiora Ladesvita Hany Yusmaini Harastha Qinthara Mathilda Hardini, Niniek Harumi Kusuma Wardani Heri Wibisono Heristyorini, Ayodya Hikmah Muktamiroh Indra Setiawan Indra Setiawan Kevina Nuraini Yusuf Kevina Nuraini Yusuf Laura Hotdiana Lisa Safira Makkiyah, Feda Anisah Malvin Dharma Wiratama Manpan Drajat Maria Selvester Thadeus Marie Selvester Thadeus Marlina Dewiastuti Marlina Dewiastuti, Marlina Mashoedojo Mashoedojo Maulida, Ika Meiskha Bahar Muhammad Afrian Wiji Pratama Muhammad Ferrel Privansyah Cader Cader Muhammad Harahap Muhammad Reiza Musthafa, Zainal Nasrulloh, Nanang Naufal Hilmi Andrisha Ningsih, Sri Rahayu Niniek Hardini Nugrahayu Widyawardani Nugrahayu Widyawardani Pangaribuan, Kia Iglesias Panji Octo Prasetio Panji Octo Prasetio Prijo Sidipratomo Pritha Maya Savitri Purba, Raja Soaloon Purwaningastuti, Diana Agustini Rachmawati, Alfira Rafi Raihan Retno Yulianti Ria Maria Theresa Runinda Pradnyamita Safira, Lisa Salma Tania Simanjuntak, Kristina Sisca Erlita Soroy Lardo Sri Wahyuningsih Sri Wahyuningsih Sunarya, Putri Amelia Taufiq Fredrik Pasiak Theodore, Ishak Ramos Tri Faranita Tri Faranita Uswatun Hasanah Via Arsita Dewi Wahyukarno Wahyukarno Wibowo, Naufal Rafi Kusuma Widianingsih Widianingsih Widyaningrum, Chairunisa Widyanto, Didit Winda Lestari Yanti Harjono Hadiwiardjo Yanto Sandy Tjang Yosha Putri Wahyuni Zainal Musthafa