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All Journal Biospecies Biosfer: Jurnal Tadris Biologi JURNAL ILMIAH MANAJEMEN & BISNIS PENA SAINS Owner : Riset dan Jurnal Akuntansi SULTANIST: Jurnal Manajemen dan Keuangan JENIUS (Jurnal Ilmiah Manajemen Sumber Daya Manusia) Jurnal Ilmiah Biologi Eksperimen dan Keanekaragaman Hayati (J-BEKH) International Journal of Business Economics (IJBE) Jurnal Ilmiah Biologi UMA (JIBIOMA) Jurnal Akuntansi, Manajemen dan Ilmu Ekonomi (JASMIEN) Jurnal Pengabdian Kepada Masyarakat (JPKM) Tabikpun Jurnal Abdi Masyarakat Indonesia International Journal of Economic, Business, Accounting, Agriculture Management and Sharia Administration (IJEBAS) Al-Khidmah Jurnal Pengabdian Masyarakat Jurnal Ilman: Jurnal Ilmu Manajemen Journal of International Conference Proceedings Jurnal Pengabdian Pada Masyarakat Filogeni: Jurnal Mahasiswa Biologi BULLET : Jurnal Multidisiplin Ilmu AMMA : Jurnal Pengabdian Masyarakat Indonesian Journal of Forestry Research Analit: Analytical And Environmental Chemistry
Farisi, Salman
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Journal : PENA SAINS

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METHANOL EXTRACT PROFILE OF Eucheuma cottonii AS AN ANTIMALARIAL CANDIDATE Setyaningrum, Endah; Farisi, Salman; Sari, Galuh Retno; Arifiyanto, Achmad
JURNAL PENA SAINS Vol 11, No 2 (2024): Jurnal Pena Sains
Publisher : Program Studi Pendidikan IPA, Fakultas Ilmu Pendidikan, Universitas Trunojoyo Madura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21107/jps.v11i2.25437

Abstract

Malaria is a tropical disease that endangers public health which is caused by the plasmodium parasite, and transmitted through the bite of a female Anopheles sp. mosquito. Malaria is a major health problem in Indonesia due to its high risk of transmission and drug resistance. This encourages a study to look for other antimalarial alternatives by utilizing natural ingredients. The purpose of this study is to identify the functional groups found in Eucheuma cottonii secondary metabolites using methanol 70% as the solvent. This study is included in the experimental research. The functional group of methanol extract of Eucheuma cottonii was evaluated using Fourier Transform Infrared (FT-IR) Nicolet iS 10 spectrometers. The FT-IR analysis identified the O-H functional group at 3347.1 cm-1, C≡C at 2094.8 cm-1, C=C at 1632.6 cm-1, phenol or O-H bend at 1401.5 cm-1, aromatic C-O at 1192.7 cm-1, and a C-C group at 1043.7 cm-1. The results of phytochemical analysis on Eucheuma cottoni revealed the presence of saponins. The functional groups formed in the 70% methanol extract of Eucheuma cottonii seaweed are the O-H, C≡C, C=C, phenol or O-H bend, aromatic C-O, and C-C groups which are flavonoid compounds in the flavanone group which have the potential to be antimalarial. Furthermore, the presence of the O-H, C=O, C-O, C=C, or C-H functional groups is a characteristic of a flavonoid compound. Therefore, it can be concluded that the identified functional groups indicate the existence of flavonoid molecules from the flavanone group, which potential as antimalarial properties.
Co-Authors Abdul Aziz Abinawanto Acai Sudirman Amelia, Mays Andi Prayogi, Muhammad Arie Mangesti, Yovita Arifiyanto, Achmad Aspita Laila Azizah, Enur Bambang Irawan Bambang Irawan /E21207042 Chairul Farid, Achmad Christina Nugroho Ekowati, Christina Nugroho Dahlan, Rudiyanto Dhillon, Aishwar Shaqilla Kaur Endah Setyaningrum, Endah Endang Nurcahyani Frans Simangunsong Guntur, Sundaru Hendri Busman Hutauruk, Elisa Marcelina Ikhsan Ikhsan Imron, Muhamad Insan Qudus, Hardoko Jani Master, Jani Jasman Saripuddin Hasibuan Jufrizen Juliana, Elfi Lestari, Mutia Dinda Linirin Widiastuti, Endang Lovitya Trisnanti, Ines Maryani, Rina Meliandani, Winda Mohammad Mohammad Muhammad Andi Prayogi Muhammad Arif Muhammad Irsan Murtadlo, Aly Muslim Muslim Mutmainah, Nurul Aniqotun Nasution, Azly Anggraini Nazma, Anya Khalisza Putri Ningsih, Agung Setia Nukmal, Nismah Nur Hayati Nurhayati Nurhayati Nurhayati Pramesti, Nouriza Agfa Pratama Widiarsa, Anang Pratama, Nugraha Primasari Pertiwi Puji Utomo, Sutrisno Pulungan, Khairul Anwar Putra Samudra, Kaharudin Putri, Jean Delliana Putri, Sriana Rima, Komang Rimbawani Sushanty, Vera Rini Astuti Rochmah Agustrina Ronny Ronny RR. Ella Evrita Hestiandari Saidan Sany Lubis Sari, Galuh Retno Sazilly, Muhamad Rizkci Sembiring, Rinawati Septi Prihantini, Baiq Nur Iman Sibarani, Tagor Slamet Suhartono Sumard, Sumard Sumardi Sumardi . suratman Suratman Suratman Suratman Umar Susanto, Gregorius Nugroho Syah, Amirul Syofyan Hadi Tengku Riza Zarzani N Tri Budiman, Nanang Tugiyono Tugiyono Tugiyono Umi Kalsum Walujo Tjahjono, Agus YUDI SISWADI Yulianty Yulianty Yulianty YUNITA