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Journal : JIKA

SKRINING FITOKIMIA DARI INFUSA DAN EKSTRAK ETANOL DAUN LIDAH MERTUA (Sansevieria trifasciata Prain) Deri Islami; Dedi Kurniawan
Jurnal Ilmu Kesehatan Abdurrab Vol 1 No 2 (2023): Volume 1 Nomor 2 Juni 2023
Publisher : LPPM Universitas Abdurrab

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Abstract

Sansevieria trifasciata prain, known to the public as the tongue-in-law plant, is one of the medicinal plants in Indonesia. Traditionally, this plant, which originates from the tropical African continent, is often used as an antiseptic and antimicrobial. The efficacy of mother-in-law's tongue in curing various diseases is also thought to be related to the chemical compounds it contains, including the leaves and rhizomes of mother-in-law's tongue contain secondary metabolites of the cardenolin group, besides that the leaves also contain flavonoids, tannins and polyphenols. This study aims to determine the phytochemical content of infusion and ethanol extract of mother-in-law's tongue (Santieviera trifasciata prain). This study used two methods, namely multilevel maceration and infusion. This study aims to determine the phytochemical content of infusion and ethanol extract of mother-in-law's tongue (Santieviera trifasciata prain). The results of the phytochemical screening test from the infusion and ethanol extract of Mother-in-law's tongue (Sanseivieria trifasciata prain) leaves contain different chemical compounds, namely the phytochemical screening on the ethanol extract contains alkoloids, flavonoids, terpenoids and tannins compounds. Meanwhile, the infusion phytochemical screening only contained alkoloids and saponin compounds.
EVALUASI SEDIAAN SABUN CAIR ANTISEPTIK EKSTRAK ETANOL LIDAH MERTUA (Sansevieriae trifasciata Prain) Deri Islami; Tika Anggraini
Jurnal Ilmu Kesehatan Abdurrab Vol 1 No 2 (2023): Volume 1 Nomor 2 Juni 2023
Publisher : LPPM Universitas Abdurrab

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Abstract

Tongue-in-law (Sansevieria trifasciata Plain) is a plant originating from the African continent. This plant is known as an antiseptic. The compounds contained in the tongue-in-law plant that have a role as antiseptics are flavonoids, phenols, and saponins because the active substance compounds contained in the ethanol extract of tongue-in-law can inhibit bacterial growth. This study aims to evaluate the preparation of liquid soap of ethanol extract of tongue-in-law with a concentration of 1%, 3%, and 5%. The method used in this research is a laboratory experiment regarding the evaluation of liquid soap preparations including organoleptic testing, pH, foam height, specific gravity, and free alkali. The test results of liquid soap preparations are determined by the quality requirements of SNI 06-4085-1996. The observation results of pH testing obtained F0 and F1 values did not meet the quality requirements of SNI 06-4085-1996, while F2 and F3 met the quality requirements of SNI 06-4085-1996. Specific gravity test on samples F0, F1, F2, and F3 did not meet the requirements of SNI 06-4085-1996. While the foam height test on F0, F1, F2, and F3 meets the quality requirements of SNI 06-4085-1996. Free alkali testing on liquid soap obtained values of F0, F1, F2, and F3 did not meet the quality requirements of SNI 06-4085-1996.
Evaluation of The Use Antituberculosis Drugs and Analysis of Adherence Pulmonary Tuberculosis Patients at The Sidomulyo Health Center, Pekanbaru Pratiwi, Denia; Maisarah, Maisarah; Islami, Deri
Jurnal Ilmu Kesehatan Abdurrab Vol 1 No 4 (2023): Vol 1 No 4 Desember 2023
Publisher : LPPM Universitas Abdurrab

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Tuberkulosis (TB) Adalah penyakit menular yang disebabkan oleh bakteri Mycobacterium tuberculosis. Berdasarkan data dari Global Tuberculosis Report tahun 2022, Indonesia menempati peringkat kedua kasus TB tertinggi setelah India. Penelitian ini bertujuan untuk mengevaluasi kesesuaian penggunaan OAT pada pasien tuberkulosis paru di Puskesmas Sidomulyo pekanbaru dari bulan Januari-Desember tahun 2022 berdasarkan Pedoman Penanggulangan Tuberkulosis tahun 2014 oleh Kemenkes RI, serta hubungan antara faktor umur, lama pengobatan, jenis kelamin, dan penyakit penyerta kronik terhadap hasil pengobatan pasien, dan analisis tingkat kepatuhan pasien TB paru. Penelitian ini merupakan penelitian deskriptif non eksperimental dengan pengambilan data secara retrospektif. Hasil penelitian didapatkan bahwa jenis OAT yang diberikan yaitu OAT jenis KDT (Kombinasi Dosis Tetap) sebesar 99 % dengan angka kesembuhan mencapai 80%. Kesesuaian indikasi, dosis dan pemilihan kombinasi OAT telah sesuai standar Pedoman Penanggulangan TB nasional tahun 2014. Analisis hubungan antara beberapa faktor terhadap hasil pengobatan pasien yang didapatkan dari hasil analisis statistik uji chi-square disimpulkan bahwa faktor umur (p=0,00001; p<0,05) memiliki hubungan yang bermakna sedangkan jenis kelamin (p=0,064; p>0,05), lama pengobatan (p=0,860; p>0,05) dan penyakit penyerta kronik (p=0,826; p>0,05) tidak memiliki hubungan yang bermakna terhadap hasil pengobatan pasien. Tingkat kepatuhan pasien yang didapatkan dari hasil pengisian kuisioner pasien TB paru di Puskesmas Sidomulyo memiliki kepatuhan tinggi sebesar 49%.
Formulasi dan Evaluasi Sediaan Pelembab Bibir (Lip Balm) Menggunakan Ekstrak Kulit Nanas (Ananas Comomus L. Merr). utama, vonny kurnia; Islami, Deri; Sundary, Nining
Jurnal Ilmu Kesehatan Abdurrab Vol 1 No 3 (2023): Volume 1 Nomor 3 September 2023
Publisher : LPPM Universitas Abdurrab

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Abstract

Pineapple peel waste is not utilized properly, but which of ingredients such as vitamin C and flavonoid. It can be used as cosmetic ingredients such as lip balm preparations. The purpose of this study was to find out the good pineapple peel extract lip balm. The pineapple peel extract was formulated in the form of lip balm using various concentrations of pineapple peel extract 1, 2, and 3% evaluating the good physical properties of the lip balm preparation. The evaluation of lip balm were evaluated in formulation of organoleptic, melting point, homogenity, pH, spread ability and iritasion. Results showed that the testing each achieved good. The homogeneity test shows that each preparation is homogeneous. The pH of F1, F2, and F3 were fulfilled in at a range 4,5-6,5. The spread ability of F1, F2 and F3 were 5.34, 6.2 and 5.74, respectively. The melting point of each preparation melts well. Lip balm obtaind not cause irritation to the skin. The best formula were F2 at concentration of 2% because it had a texture that is not too hard, had a good pH and had good spread ability.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN MATOA (Pometia pinnata J.R. Forst. & G. Forst) Islami, Deri; Falakhudin, Khoirul Anam; Suardi, Muslim
Jurnal Ilmu Kesehatan Abdurrab Vol 2 No 1 (2024): Volume 2 Nomor 1 Maret 2024
Publisher : LPPM Universitas Abdurrab

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Abstract

Matoa (Pometia pinnata J.R. Forst. & G. Forst) can be used as traditional medicine. The plant contains secondary metabolite compounds such as flavonoids, tannins, terpenoids and saponins that have the ability to inhibit the mechanism of action of bacteria. The purpose of this study was to determine the antibacterial activity of n-hexane, ethyl acetate and ethanol extracts of Matoa leaves against gram-positive bacteria Staphylococcus aureus and Streptococcus mutans and gram-negative bacteria Escherichia coli and Klebsiella pneumonia at concentrations of 70, 50, 30 and 10% using the disc diffusion method, Ciprofloxacin as a positive control and DMSO as a negative control. Statistical test results on 70% concentration of ethyl acetate extract showed average results on the inhibition diameter of Staphylococcus aureus, Streptococcus mutans, Eschericia coli and Klebsiella pneumenia were 10.63, 13.43, 11.23, and 13.26 mm, respectively. Based on the results of this study, it can be concluded that the n-hexane, ethyl acetate and ethanol extracts of Matoa Leaf (Pometia pinnata J.R. Forst. & G. Forst) have the ability to inhibit the growth of gram-positive bacteria Staphylococcus aureus and Streptococcus mutans and gram negative bacteria Escherichia coli and Klebsiella pneumonia, but in the n-hexane extract of matoa leaves is not able to inhibit the growth of Staphylococcus aureus.