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Fitri, Nurul
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Journal : FARMASAINKES

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FORMULASI DAN UJI AKTIVITAS DEODORANT STICK EKSTRAK ETANOL DAUN SIRIH MERAH (Piper ornantum N.E.BR ) TERHADAP BAKTERI staphylococcus epidermidis Fitri, Nurul; Rani, Zulmai; Lubis, Minda Sari; Nasution, Haris Munandar
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 4 No. 2 (2025): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v4i2.4163

Abstract

Red betel leaf (Piper ornatum N.E.Br) is one of several plants that have antibacterial properties so that it can be selected as an active ingredient in deodorants because of its effectiveness as an antibacterial. Red betel leaf contains secondary metabolites, namely alkaloids, flavonoids, tannins and essential oils. The purpose of this study was to determine the formulation of ethanol extract of red betel leaf (Piper ornatum N.E.Br) made in the form of a deodorant stick preparation with good characteristics and to determine the concentration of the deodorant stick preparation in inhibiting Staphylococcus epidermidis bacteria. The study was conducted experimentally including the manufacture of extracts by the maceration method. In this study, ethanol extract of red betel leaf with concentration variations of 1, 2 and 3%. The preparation was tested for organoleptic, homogeneity, pH, melting time, melting point, and antibacterial activity. The content of the phytochemical screening results of the ethanol extract of red betel leaf showed that there were flavonoids, alkaloids, tannins, saponins, and triterpenoids so that they have the potential to inhibit bacteria. The resulting deodorant stick meets the requirements of pH test, melting time test, melting point test and has bacterial inhibitory activity. At a concentration of 1% it is categorized as moderate with an inhibition zone of 6-10 while for a concentration of 2% and 3% it is categorized as strong with an inhibition zone of 10-20 mm.
Co-Authors Abdul Karim Abdul Malik Ade Kumalasari Ahmad Fauzan Ahmad Syukri Ali, Mad Amin, Asni Amin, Ihya Fakhrurizal Aminah Aminah Amirullah -, Amirullah Andi Maslia Tenrisau Adam Andini, Hani Ar-Razy, Fadil Muhammad Ardiansyah, Muh. Arifuddin Arifuddin Asni Amin Atarigsyah, Muhamad B., Indayani Bambang Suharjito Barus, Desli Natalia Bunga, A. Tenri Dewi Aprilia Dewi Yuliana Dina Maulina Dinata, Diva Dinata, Ridho Praja Dinawati Trapsilasiwi Efa Silfia Efendi, Cahyaningsih Eroza, Aprilia Ervin Oktavianingtyas Fachrizal, Muhammad Fadli, Faisal Fahmi, Muhammad Najib Febriyanti, Shella Firdaus Firdaus Fitria Ulfah Hamdillah, Andi Haris Munandar Nasution Haswendra, Aditya Reza Husaini, Fauzan Istiqamah, Istiqamah Jufrizal Jufrizal Justam, Justam Khidayatul Munawwaroh Kurniawan, Fahmi Lubis, Minda Sari M. Hasanuddin Mala Nurilmala Mardiah Mardiah Maulida, Cut Wellee Meivita, Dewi Miftuhatis, Ina Nabila, Syarifah Nur Qamariah Nurmiati Nurmiati Oktofia, Erna putri Juni Astuti, Dina Putri, Sasqia Qisthi, Amara Retno Kusniati Ridho, Muhammad Andi Ali Rijadi, Arief Risda Waris, Risda Rosmalah Rosmalah, Rosmalah Rustan, Edhy Sabirin Sabirin, Sabirin Saifuddin Ali Anwar Sanny, Arief Maulana Sarbi, Sukadji Sembiring, Rinawati Septiani, Indri Simatupang, Teresia Artati Oktaviani Siti Aisyah Suarilah, Ira Suhaeti, Suhaeti Sulistia, Fransiska Sumarni Sumarni Sumarno . Supriadi, Rinaldi Suradi, Ahmad Syahadat, Edy Fitriawan Trapsilo Prihandono Tri Apriadi Tsalis Kurniawan Husain, Tsalis Kurniawan Tunnur, Alvia Umie Lestari Usman, Muktamir Vienendra, Ridwan Wardani, Arini Dwi Wennyta, Wennyta Wenti, Sisra Yanti Ismiyati, Yanti Yazid, Syahrul Abdul Yulianawati, Dewi Yulis Setiya Dewi Zahra, Afifatuz Zulmai Rani