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All Journal Amerta Nutrition World Nutrition Journal PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Promotif Preventif Berita Kedokteran Masyarakat Journal of Indonesian Specialized Nutrition Media Penelitian dan Pengembangan Kesehatan Jurnal Epidemiologi Kesehatan Indonesia
Sundjaya, Tonny
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Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Pengembangan Permen Jelly "Previmin” Multivitamin Mineral untuk Pencegahan Stunting: Pengembangan Permen Jelly ”Previmin” Multivitamin Mineral untuk Pencegahan Stunting Ryveka, Aurellia; Lestari, Lily Arsanti; Pratiwi, Dessy; Sundjaya, Tonny
Amerta Nutrition Vol. 7 No. 3SP (2023): AMERTA NUTRITION SUPPLEMENTARY EDITION
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v7i3SP.2023.10-19

Abstract

Background: The prevalence of stunting in Yogyakarta province has decreased in 2022, although it hasn't reached the target of 14%. The Taburia supplementation program, implemented by the Indonesian government in 2010, aimed to address this issue, but its effectiveness remains a concern. Therefore, in 2017 jelly candy with fortification of Taburia and prebiotics fructooligosaccharides was developed as well as an organoleptic test in preschool and kindergarten children. Subsequently, in 2022, the production of the same jelly candy, named "Previmin" was upscaled and carried out in a factory. Production on a factory scale can change the nutritional contents and organoleptic properties of the product. Objectives: To evaluate the organoleptic properties, acceptability, and nutritional content of factory-scale "Previmin” jelly candy. Methods: This was true experimental study carried out in Kalurahan Sumberarum, Kapanewon Moyudan, Sleman District, Yogyakarta to evaluate the organoleptic properties and acceptability of jelly candy "Previmin'' on 59 toddlers. The production process was conducted by PT Natural Food Success, whereas nutritional content analysis was carried out in BBSPJIA Laboratory Bogor. Results: Based on organoleptic tests, the color, flavor, taste, and texture score were above 5 points hence respondents liked "Previmin”. As many as 75% of respondents could consume the product hence Previmin's acceptability was good. Nutritional content, heavy metals, and microbial count have good results and comply with SNI standards. Conclusions: Most toddlers like and can consume "Previmin” jelly candy. "Previmin” jelly candy contains a good source of macronutrients and micronutrients as well as has complied with SNI standards.
Indikator Biokimia untuk Identifikasi Anemia Defisiensi Besi di Indonesia: Tinjauan Literatur: Indikator Biokimia untuk Identifikasi Anemia Defisiensi Zat Besi di Indonesia Helmyati, Siti; Hasanah, Fina Cahya; Putri, Febriani; Sundjaya, Tonny; Dilantika, Charisma
Amerta Nutrition Vol. 7 No. 3SP (2023): AMERTA NUTRITION SUPPLEMENTARY EDITION
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v7i3SP.2023.62-70

Abstract

Background: The World Health Organization (WHO) states that adolescents are at risk of developing anemia. The initial step in identifying iron deficiency anemia (IDA) is through screening. In addition, the WHO framework aims to accelerate the reduction of anemia worldwide by achieving specific goals, including an increase in anemia screening. Objectives: This study aims to determine the use of biochemical indicators in screening for the identification of IDA status in Indonesia. Methods: Literature searches were conducted in the PubMed, Scopus, ScienceDirect, and Garuda databases following the PRISMA guidelines. Articles from journals indexed in Scopus Q1 to Q4 or Sinta 1 to Sinta 3 with an experimental or observational research design in Indonesia were reviewed. Discussion: Anemia screening was performed to determine IDA status, which was measured by the following parameters: hemoglobin (Hb), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC). Hb is an indicator of IDA in populations with a high prevalence of IDA. MCV is calculated by dividing hematocrit by red blood cell count. MCH refers to the average absolute hemoglobin content of the red blood cells, while MCHC refers to the concentration of hemoglobin in the red blood cells. Serum ferritin (SF) is a highly reliable and sensitive indicator for assessing iron stores and clinical status in the field. In addition, serum transferrin receptor (STfR) is a more stable indicator than serum transferrin (ST). SF can differentiate between IDA caused by anemia or chronic diseases. Conclusions: Combining hemoglobin and SF improves sensitivity and specificity in detecting the severity of IDA. STfR can also be used as an indicator for IDA. The use of the STfR and SF indicators is the best biochemical approach to IDA.
THE RELATIONSHIP OF DIETARY PATTERNS, PHYSICAL ACTIVITY, AND SCREEN TIME WITH THE INCIDENCE OF OVERWEIGHT AMONG TODDLER AGED 24–59 MONTHS IN SUDIMARA PINANG HEALTH CENTER AREA, TANGERANG CITY Zahra, Audia; Paramita, Farah; Supriyadi; Kurniawan, Agung; Sundjaya, Tonny
Journal of Indonesian Specialized Nutrition Vol. 3 No. 3 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i3.51

Abstract

Background: Overweight in toddlers may further develop into obesity. The Sudimara Pinang Community Health Center area has the highest number of overweight toddlers in Tangerang City. This study aims to examine the relationship between dietary patterns, physical activity, screen time, and the incidence of overweight among toddlers aged 24-59 months in Sudimara Pinang area. Method : This study employed a quantitative approach with a cross-sectional study design. A total of 93 toddlers were purposively selected from the five integrated health posts with the highest number of overweight toddlers. Nutritional status was assessed using anthropometric measurements. Dietary patterns were measured with a Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ), Physical activity with the Early Year Physical Activity Questionnaire (EY-PAQ), and screen time with the Seven in Seven Screen Exposure Questionnaire. Result: The findings revealed a significant association between dietary pattern (p-value = 0.016), and between physical activity and overweight incidence (p-value = 0.000). However, no significant relationship was found between screen time and overweight (p-value = 0.523). Conclusion: Dietary patterns and physical activity were significantly associated with overweight among toddlers, whereas screen time showed no significant relationship. These findings highlight the need for comprehensive intervention programs in the area, focusing on promoting healthy eating and physical activity.
Gizi Ibu: Fondasi Menyusui dan Masa Depan Anak: Maternal Nutrition: The Foundation of Breastfeeding and Beyond Basrowi, Ray Wagiu; Darus, Febriansyah; Sundjaya, Tonny; Arumndari, Runi
Amerta Nutrition Vol. 9 No. 4 (2025): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v9i4.2025.735-746

Abstract

Background: Breastmilk from a healthy and well-nourished mother serves as the optimal source of nutrition for infant growth and development. The composition of breastmilk is affected by maternal dietary patterns. Beyond its nutritional value, breastfeeding fosters emotional bonding between the mother and infant. Objectives: This study aims to explore the role of maternal nutrition in breastfeeding success and infant’s well-being through scientific and philosophical lenses. Methods: Literature search was conducted via PubMed (Medline Database), including systematic reviews, meta-analyses, and original research articles published within the last decade (2014-2024). The following keywords were utilised: ("maternal nutrition" OR "maternal health" OR "breastfeeding practice" OR "breastmilk") AND ("neurodevelopment" OR "intellectual development" OR "child development"). Inclusion criteria comprised open-access articles, while studies were available only in abstract form were excluded. Discussions: Breastmilk production requires an adequate intake of macronutrients, including protein, carbohydrates, and fats; thus, maternal dietary intake significantly affects breastmilk composition. The nutritional and bioactive components in breastmilk support the infant’s immune function, neurodevelopment, and physical growth, while simultaneously  providing necessary energy for the lactating mother. Breastfeeding should be understood as a holistic practice that extends beyond nutrient transfer, necessitating multisectoral collaboration involving government, non-governmental organizations, healthcare providers, and the population at large. Conclusions: Maternal well-being is intrinsically linked to child health, as well-nourished mothers provide a vital foundation for optimal infant development. A compassionate, community-based approach to maternal nutrition is an essential view that respects individual choices while emphasizing the importance of collective support to enhance the health and well-being of both mother and child.
An Epidemiological Exploration of Binge Eating Disorder and Its Emotional Roots among Youth in Greater Jakarta Kurniati, Henny; Asy'ari, Yudha; Helmi, Tri Amelia Rahmitha; Sundjaya, Tonny
Jurnal Epidemiologi Kesehatan Indonesia Vol. 9, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The rising prevalence of mental disorders among youth, including depression, anxiety, stress, and binge eating disorder (BED), has become a major concern in the context of global mental health. BED, as a form of eating disorder, often occurs with psychological conditions such as anxiety and depression, complicating diagnosis and treatment. This study aimed to investigate the prevalence and association between depression, anxiety, stress, and BED among youth in Greater Jakarta. Using a cross-sectional online design, data were collected from 231 participants aged 18-25 years through the Binge Eating Scale (BES) and Depression Anxiety Stress Scale-21 (DASS-21). Statistical analysis involved bivariate testing and logistic regression to identify risk factors and association among variables. This study indicated that BED prevalence was higher among female respondents and individuals with a BMI ≥25. Anxiety emerged as the primary factor increasing the risk of BED by up to four times, while stress was not a significant predictor. These findings emphasized the importance of early detection and psychological interventions, as well as preventive approaches such as routine screening and improved access to mental health services for youth. In conclusion, anxiety and obesity were key factors that need comprehensive management to reduce BED occurrence and enhance adolescent mental health. Keywords : Anxiety, Binge Eating Disorder, Depression, Stress, Youth
The role of inflammatory biomarkers in adolescent major depressive disorder: a systematic review Kwarta, Cityta Putri; Sari, Mike Permata; Suharti; Sundjaya, Tonny; Novitasari, Prihatini Dini; Taufik, Kumar
Berita Kedokteran Masyarakat Vol 42 No 01 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/bkm.v42i01.23244

Abstract

Purpose: Major Depressive Disorder (MDD) in adolescents is an escalating mental health problem with underlying biological pathways. Increasing evi- dence highlights the role of inflammatory response and immune dysregulation in its development and progression. This study aims to explore the role of inflammatory biomarkers in Major Depressive Disorder (MDD) among adolescent populations, elucidating their potential utility for more effective treatment strategies. Methods: A systematic review was conducted using Ebsco, PubMed, Scopus, Web of Science, and Google Scholar databases. Studies published between 2019 and 2025 that focused on adolescent MDD (aged 10-19 years) and inflammation were included. Study quality was evaluated using the Joanna Briggs Institute (JBI) tool, and narrative analyses were conducted for data synthesis. The PICOS (Population, Intervention, Comparison, Outcome, and Study Design) framework is used to ensure clarity in defining the research question and inclusion criteria. The systematic review was registered in PROSPERO (CRD420251129403). Results: A total of 29 articles met the inclusion criteria for this study. Across the included studies, elevated levels of pro-inflammatory cytokines, particularly inter- leukin-6 (IL-6) and Tumor Necrosis Factor-Alpha (TNF-α), were consistently associated with MDD in adolescents. Dysregulation of the Hypothalamic- Pituitary-Adrenal (HPA) axis and alterations in anti-inflammatory cytokines such as IL-10 were also observed. These biomarkers were linked to changes in stress hormone regulation. Conclusion: Inflammatory biomarkers play a significant role in the pathophysiology of MDD among adolescents, offering promising avenues for early detection and personalised intervention. Integrating biomarker assessment into clinical practice may improve diag- nosis and guide targeted treatments.
Perspective of Soy Formula and Fiber intake among Non-Cow’s Milk Drinker Pediatric Patients; A Survey among Indonesian Health Care Practitioners Basrowi, Ray Wagiu; Wasito, Erika; Sundjaya, Tonny
World Nutrition Journal Vol. 4 No. S1 (2020): Special Issue : Soy Plant-based and Fiber in Children’s Gut Health, Growth & D
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.S1.0002

Abstract

Indonesia is one of the highest countries for soy-based product consumption, which the usage also started from early age as breastmilk substitute product, although local regulation and guideline stated that soy-based formula recommended for cow’s milk protein allergy. However, evidences showed that soy-based formula supplemented with fiber in non-cow’s milk drinker could also have health effect to gastrointestinal system. This online survey aimed to explore the perspective of health care practitioners (HCPs) in recommending soy-based formula for non-cow’s milk drinker pediatric patients, as well as identify the required additional ingredient or supplementation, specifically on fiber, in soy-based formula. Majority of respondents (97% of paediatricians (P < 0.001)), (96% of nurses  (P = 0.003)), (99% of midwives (P < 0.001)) recommended soy-based formula as nutritional product toward non-cow’s milk drinker patients. On the added ingredients required, 43% of respondents mentioned that AA and DHA and 31% mentioned that fibre is the ingredient that need to be added to complete the benefits of soy formula. This study concluded that the overall perspective of HCPs showed that soy-based formula is a nutritional product recommended for non-cow’s milk pediatric patients. However, fiber is required to be added to achieve the potential benefits of soy-based formula.
Indonesian health care practitioner’s perception on gut-brain-axis and social-emotional concept Basrowi, Ray Wagiu; Sundjaya, Tonny
World Nutrition Journal Vol. 5 No. S2 (2022): Special Issue : critical aspects of early life nutrition, gut health, and deve
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V05.S2.0005

Abstract

Background The microbiome-gut-brain-axis (GBA) concept has long been appreciated. It is recognized that the microbes resident in the gastrointestinal tract can influence brain physiology and the social-development competencies, and vice versa. Therefore, it is crucial for health care practitioners (HCPs) to understand this concept, especially in children; however, no study has been reported. Methods: This study used qualitative methods to explore HCPs’ perception and awareness about the microbiome-GBA concept. Data were collected through in-depth interviews using online video calls with HCPs, including general practitioners, pediatricians, and midwives. Results: We found that responders are aware of the microbiome-GBA concept, as this issue is often discussed in seminars and other events. They realized that gut health is a significant concern, and it is significantly impacting brain health and leads to social and emotional development (SED). This process starts from the early stages of life. Conclusion: The HCPs in our study have a good perception of the microbiome-GBA concept, e.g., a healthy brain is not possible without a healthy gut. As far as we are concerned, this is the first study to investigate the knowledge of HCPs about bidirectional communication of microbiome-GBA as an essential factor in child management.
Evidence on the importance of gut microbiota for the immune system Surapsari, Juwalita; Oktarina, Molly Dumakuri; Sundjaya, Tonny; Wasito, Erika
World Nutrition Journal Vol. 6 No. S2 (2023): Special Issue : expert perspectives on the interconnections between immunity,
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.S2.0002

Abstract

Vital to the health of the host is maintaining a delicate balance in the immune system by eliminating harmful pathogens while preserving self-tolerance to prevent autoimmunity. By regulating immune homeostasis, the gut microbiota in the gastrointestinal tract provides vital health benefits to its host. It has been demonstrated conclusively that dysbiosis of these gut microbial communities can cause immune dysregulation and autoimmunity. We attempt to examine the relationship between the gut microbiota and the regulation of the innate and adaptive immune homeostasis, which can influence the development of certain disease. This literature review of recently published research and newly discovered scientific information is intended to increase awareness of the importance of maintaining a microbiota balance in the gut for immune health of the host.
The narrative review of recent studies in understanding the relationship between gut (microbiota)-brain axis, nutrition and cognitive function Pasiak, Taufiq Fredrik; Wiguna, Tjhin; Sekartini, Rini; Surapsari, Juwalita; Sundjaya, Tonny; Wasito, Erika; Basrowi, Ray Wagiu; Kartjito, Melissa Stephanie
World Nutrition Journal Vol. 6 No. S2 (2023): Special Issue : expert perspectives on the interconnections between immunity,
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.S2.0004

Abstract

The concept of the gut (microbiota)-brain axis, which influences the development and function of the gastrointestinal, immune, neuroendocrine, and metabolic systems, is gaining popularity. Recent animal studies have demonstrated that the gut (microbiota)-brain axis also plays a role in establishing cognitive function. It is known that a disruption in the environment's microbiota balance can increase disease susceptibility in children. Historically, it has been hypothesized that neurodevelopmental disorders are the results of a disruption in children’s health. However, it is becoming clear that the gut microbiota and the central nervous system communicate in both directions, which could explain how microbiota affects cognitive function. Dietary factors also play important role in the central nervous system via the gut (microbiota)-brain axis, demonstrating the importance of nutrition in optimizing cognitive function. This narrative review of recently published studies and current knowledge aims to elucidate the relationship between the gut (microbiota)-brain axis and cognitive function, as well as the variables that may influence it.
Co-Authors Agung Kurniawan Alifah Wulandari, Alifah Amirah, Fitria Angeline, Maharani Eria Anies Irawati Arumndari, Runi Asy'ari, Yudha Aulia, Bianda Aviria Ermamilia Basrowi, Ray Wagiu Darus, Febriansyah Dilantika, Charisma Ekasiwi, Firstya Diyah Erry Yudhya Mulyani Fadil Himawan, Muhammad Fathiyyah, Nurul Fatimah, Putri Ganisia, Ainun Hasanah, Fina Cahya Helmi, Tri Amelia Rahmitha Helmyati, Siti Imeldawati, Rakhmalia Izmi Arisa Putri Lubis Kania R, Rahayu Kartjito, Melissa Stephanie Kinesya, Edwin Kurnia Sari Kurniati, Henny Kwarta, Cityta Putri Lily Arsanti Lestari Masita, Bertri Maulidya Mery Merlisia Mira Fauziah Mutiara, Nafisa Nadiyah Nadiyah Novianti, Anugrah Novitasari, Prihatini Dini Oktarina, Molly Dumakuri Paramita, Farah Pascaramadhani, Addini Pasiak, Taufiq Fredrik Perkasa, Al Ilham Ksatria Gagah Pratiwi, Dessy Purnomosari, Lupi Putri Rahmadani, Putri Putri, Az-zahra Atika Putri, Febriani Ramadani, Okta Rini Sekartini Ryveka, Aurellia SARI, MIKE PERMATA Sari, Yona Wia Sartika Septiani, Seala Setyarsih, Liani Shidiqah, Raysah Sa’diyah Siti Arifah Pujonarti Suharti Supriyadi Surapsari, Juwalita Taufik, Kumar Tjhin Wiguna Triyanti Triyanti Utami, Dessy Aryanti Wasito, Erika Winarno, Nibras Azeenshia Zahra, Audia Zakiudin Munasir Zata Ismah