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All Journal Amerta Nutrition PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Promotif Preventif Berita Kedokteran Masyarakat Journal of Indonesian Specialized Nutrition Media Penelitian dan Pengembangan Kesehatan Jurnal Epidemiologi Kesehatan Indonesia
Sundjaya, Tonny
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Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Pengembangan Permen Jelly "Previmin” Multivitamin Mineral untuk Pencegahan Stunting: Pengembangan Permen Jelly ”Previmin” Multivitamin Mineral untuk Pencegahan Stunting Ryveka, Aurellia; Lestari, Lily Arsanti; Pratiwi, Dessy; Sundjaya, Tonny
Amerta Nutrition Vol. 7 No. 3SP (2023): AMERTA NUTRITION SUPPLEMENTARY EDITION
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v7i3SP.2023.10-19

Abstract

Background: The prevalence of stunting in Yogyakarta province has decreased in 2022, although it hasn't reached the target of 14%. The Taburia supplementation program, implemented by the Indonesian government in 2010, aimed to address this issue, but its effectiveness remains a concern. Therefore, in 2017 jelly candy with fortification of Taburia and prebiotics fructooligosaccharides was developed as well as an organoleptic test in preschool and kindergarten children. Subsequently, in 2022, the production of the same jelly candy, named "Previmin" was upscaled and carried out in a factory. Production on a factory scale can change the nutritional contents and organoleptic properties of the product. Objectives: To evaluate the organoleptic properties, acceptability, and nutritional content of factory-scale "Previmin” jelly candy. Methods: This was true experimental study carried out in Kalurahan Sumberarum, Kapanewon Moyudan, Sleman District, Yogyakarta to evaluate the organoleptic properties and acceptability of jelly candy "Previmin'' on 59 toddlers. The production process was conducted by PT Natural Food Success, whereas nutritional content analysis was carried out in BBSPJIA Laboratory Bogor. Results: Based on organoleptic tests, the color, flavor, taste, and texture score were above 5 points hence respondents liked "Previmin”. As many as 75% of respondents could consume the product hence Previmin's acceptability was good. Nutritional content, heavy metals, and microbial count have good results and comply with SNI standards. Conclusions: Most toddlers like and can consume "Previmin” jelly candy. "Previmin” jelly candy contains a good source of macronutrients and micronutrients as well as has complied with SNI standards.
Indikator Biokimia untuk Identifikasi Anemia Defisiensi Besi di Indonesia: Tinjauan Literatur: Indikator Biokimia untuk Identifikasi Anemia Defisiensi Zat Besi di Indonesia Helmyati, Siti; Hasanah, Fina Cahya; Putri, Febriani; Sundjaya, Tonny; Dilantika, Charisma
Amerta Nutrition Vol. 7 No. 3SP (2023): AMERTA NUTRITION SUPPLEMENTARY EDITION
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v7i3SP.2023.62-70

Abstract

Background: The World Health Organization (WHO) states that adolescents are at risk of developing anemia. The initial step in identifying iron deficiency anemia (IDA) is through screening. In addition, the WHO framework aims to accelerate the reduction of anemia worldwide by achieving specific goals, including an increase in anemia screening. Objectives: This study aims to determine the use of biochemical indicators in screening for the identification of IDA status in Indonesia. Methods: Literature searches were conducted in the PubMed, Scopus, ScienceDirect, and Garuda databases following the PRISMA guidelines. Articles from journals indexed in Scopus Q1 to Q4 or Sinta 1 to Sinta 3 with an experimental or observational research design in Indonesia were reviewed. Discussion: Anemia screening was performed to determine IDA status, which was measured by the following parameters: hemoglobin (Hb), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC). Hb is an indicator of IDA in populations with a high prevalence of IDA. MCV is calculated by dividing hematocrit by red blood cell count. MCH refers to the average absolute hemoglobin content of the red blood cells, while MCHC refers to the concentration of hemoglobin in the red blood cells. Serum ferritin (SF) is a highly reliable and sensitive indicator for assessing iron stores and clinical status in the field. In addition, serum transferrin receptor (STfR) is a more stable indicator than serum transferrin (ST). SF can differentiate between IDA caused by anemia or chronic diseases. Conclusions: Combining hemoglobin and SF improves sensitivity and specificity in detecting the severity of IDA. STfR can also be used as an indicator for IDA. The use of the STfR and SF indicators is the best biochemical approach to IDA.
THE RELATIONSHIP OF DIETARY PATTERNS, PHYSICAL ACTIVITY, AND SCREEN TIME WITH THE INCIDENCE OF OVERWEIGHT AMONG TODDLER AGED 24–59 MONTHS IN SUDIMARA PINANG HEALTH CENTER AREA, TANGERANG CITY Zahra, Audia; Paramita, Farah; Supriyadi; Kurniawan, Agung; Sundjaya, Tonny
Journal of Indonesian Specialized Nutrition Vol. 3 No. 3 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i3.51

Abstract

Background: Overweight in toddlers may further develop into obesity. The Sudimara Pinang Community Health Center area has the highest number of overweight toddlers in Tangerang City. This study aims to examine the relationship between dietary patterns, physical activity, screen time, and the incidence of overweight among toddlers aged 24-59 months in Sudimara Pinang area. Method : This study employed a quantitative approach with a cross-sectional study design. A total of 93 toddlers were purposively selected from the five integrated health posts with the highest number of overweight toddlers. Nutritional status was assessed using anthropometric measurements. Dietary patterns were measured with a Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ), Physical activity with the Early Year Physical Activity Questionnaire (EY-PAQ), and screen time with the Seven in Seven Screen Exposure Questionnaire. Result: The findings revealed a significant association between dietary pattern (p-value = 0.016), and between physical activity and overweight incidence (p-value = 0.000). However, no significant relationship was found between screen time and overweight (p-value = 0.523). Conclusion: Dietary patterns and physical activity were significantly associated with overweight among toddlers, whereas screen time showed no significant relationship. These findings highlight the need for comprehensive intervention programs in the area, focusing on promoting healthy eating and physical activity.
Gizi Ibu: Fondasi Menyusui dan Masa Depan Anak: Maternal Nutrition: The Foundation of Breastfeeding and Beyond Basrowi, Ray Wagiu; Darus, Febriansyah; Sundjaya, Tonny; Arumndari, Runi
Amerta Nutrition Vol. 9 No. 4 (2025): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v9i4.2025.735-746

Abstract

Background: Breastmilk from a healthy and well-nourished mother serves as the optimal source of nutrition for infant growth and development. The composition of breastmilk is affected by maternal dietary patterns. Beyond its nutritional value, breastfeeding fosters emotional bonding between the mother and infant. Objectives: This study aims to explore the role of maternal nutrition in breastfeeding success and infant’s well-being through scientific and philosophical lenses. Methods: Literature search was conducted via PubMed (Medline Database), including systematic reviews, meta-analyses, and original research articles published within the last decade (2014-2024). The following keywords were utilised: ("maternal nutrition" OR "maternal health" OR "breastfeeding practice" OR "breastmilk") AND ("neurodevelopment" OR "intellectual development" OR "child development"). Inclusion criteria comprised open-access articles, while studies were available only in abstract form were excluded. Discussions: Breastmilk production requires an adequate intake of macronutrients, including protein, carbohydrates, and fats; thus, maternal dietary intake significantly affects breastmilk composition. The nutritional and bioactive components in breastmilk support the infant’s immune function, neurodevelopment, and physical growth, while simultaneously  providing necessary energy for the lactating mother. Breastfeeding should be understood as a holistic practice that extends beyond nutrient transfer, necessitating multisectoral collaboration involving government, non-governmental organizations, healthcare providers, and the population at large. Conclusions: Maternal well-being is intrinsically linked to child health, as well-nourished mothers provide a vital foundation for optimal infant development. A compassionate, community-based approach to maternal nutrition is an essential view that respects individual choices while emphasizing the importance of collective support to enhance the health and well-being of both mother and child.
An Epidemiological Exploration of Binge Eating Disorder and Its Emotional Roots among Youth in Greater Jakarta Kurniati, Henny; Asy'ari, Yudha; Helmi, Tri Amelia Rahmitha; Sundjaya, Tonny
Jurnal Epidemiologi Kesehatan Indonesia Vol. 9, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The rising prevalence of mental disorders among youth, including depression, anxiety, stress, and binge eating disorder (BED), has become a major concern in the context of global mental health. BED, as a form of eating disorder, often occurs with psychological conditions such as anxiety and depression, complicating diagnosis and treatment. This study aimed to investigate the prevalence and association between depression, anxiety, stress, and BED among youth in Greater Jakarta. Using a cross-sectional online design, data were collected from 231 participants aged 18-25 years through the Binge Eating Scale (BES) and Depression Anxiety Stress Scale-21 (DASS-21). Statistical analysis involved bivariate testing and logistic regression to identify risk factors and association among variables. This study indicated that BED prevalence was higher among female respondents and individuals with a BMI ≥25. Anxiety emerged as the primary factor increasing the risk of BED by up to four times, while stress was not a significant predictor. These findings emphasized the importance of early detection and psychological interventions, as well as preventive approaches such as routine screening and improved access to mental health services for youth. In conclusion, anxiety and obesity were key factors that need comprehensive management to reduce BED occurrence and enhance adolescent mental health. Keywords : Anxiety, Binge Eating Disorder, Depression, Stress, Youth
The role of inflammatory biomarkers in adolescent major depressive disorder: a systematic review Kwarta, Cityta Putri; Sari, Mike Permata; Suharti; Sundjaya, Tonny; Novitasari, Prihatini Dini; Taufik, Kumar
Berita Kedokteran Masyarakat Vol 42 No 01 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/bkm.v42i01.23244

Abstract

Purpose: Major Depressive Disorder (MDD) in adolescents is an escalating mental health problem with underlying biological pathways. Increasing evi- dence highlights the role of inflammatory response and immune dysregulation in its development and progression. This study aims to explore the role of inflammatory biomarkers in Major Depressive Disorder (MDD) among adolescent populations, elucidating their potential utility for more effective treatment strategies. Methods: A systematic review was conducted using Ebsco, PubMed, Scopus, Web of Science, and Google Scholar databases. Studies published between 2019 and 2025 that focused on adolescent MDD (aged 10-19 years) and inflammation were included. Study quality was evaluated using the Joanna Briggs Institute (JBI) tool, and narrative analyses were conducted for data synthesis. The PICOS (Population, Intervention, Comparison, Outcome, and Study Design) framework is used to ensure clarity in defining the research question and inclusion criteria. The systematic review was registered in PROSPERO (CRD420251129403). Results: A total of 29 articles met the inclusion criteria for this study. Across the included studies, elevated levels of pro-inflammatory cytokines, particularly inter- leukin-6 (IL-6) and Tumor Necrosis Factor-Alpha (TNF-α), were consistently associated with MDD in adolescents. Dysregulation of the Hypothalamic- Pituitary-Adrenal (HPA) axis and alterations in anti-inflammatory cytokines such as IL-10 were also observed. These biomarkers were linked to changes in stress hormone regulation. Conclusion: Inflammatory biomarkers play a significant role in the pathophysiology of MDD among adolescents, offering promising avenues for early detection and personalised intervention. Integrating biomarker assessment into clinical practice may improve diag- nosis and guide targeted treatments.
THE GUT-BRAIN-MICROBIOME AXIS IN CHILDHOOD OBESITY: MECHANISMS AND CLINICAL IMPLICATIONS Aulia, Bianda; Sundjaya, Tonny
Journal of Indonesian Specialized Nutrition Vol. 3 No. 4 (2025): Journal of Indonesian Specialized Nutrition
Publisher : PT. Varians Statistik Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i4.69

Abstract

Background: Childhood obesity has become a global health crisis affecting 188 million children aged 5–19 years worldwide, with serious metabolic complications. The gut–brain–microbiome axis has emerged as a key mechanistic link and therapeutic target for obesity in children. Methods: A narrative literature review was conducted using PubMed, Scopus, and Google Scholar and included studies published up to December 2025. Search terms, used in various combinations, included “childhood obesity,” “gut microbiota,” “gut–brain axis,” “targeted interventions,” “probiotic,” and “prebiotic”. Results: Childhood obesity is associated with early-life gut dysbiosis characterized by reduced diversity, higher Firmicutes/Bacteroidetes ratios, and shifts in key taxa, driven by prenatal, postnatal, and lifestyle factors. This dysbiotic microbiota enhances energy harvest, promotes low-grade inflammation and barrier dysfunction, and disrupts gut–brain axis signaling via altered short-chain fatty acids, neurotransmitter, and gut hormone profiles, thereby impairing appetite regulation and favoring positive energy balance. Emerging evidence indicates that targeting the gut microbiota–brain axis with probiotics, prebiotics, synbiotics, and fecal microbiota transplantation may improve metabolic outcomes and body composition in children with obesity. Conclusion: Gut microbiota dysbiosis contributes to childhood obesity via altered metabolism, inflammation, and gut–brain axis–mediated appetite regulation.
FACTORS ASSOCIATED WITH LOWER BIRTH WEIGHT AMONG INFANTS IN SOUTH KALIMANTAN PROVINCE, INDONESIA Winarno, Nibras Azeenshia; Pujonarti, Siti Arifah; Triyanti, Triyanti; Irawati, Anies; Perkasa, Al Ilham Ksatria Gagah; Sundjaya, Tonny; Masita, Bertri Maulidya
Journal of Indonesian Specialized Nutrition Vol. 4 No. 1 (2026): Journal of Indonesian Specialized Nutrition
Publisher : PT. Varians Statistik Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v4i1.70

Abstract

Background: According to the thrifty phenotype hypothesis, individuals who have a Birth Weight less than 3000 grams are at risk of suffering from metabolic syndrome and type 2 diabetes mellitus in adulthood. The prevalence of Diabetes Mellitus and metabolic syndrome in Indonesia and South Kalimantan is increasing. In 2023, the Indonesian Health Survey (Survey Kesehatan Indonesia /SKI) data showed that the percentage of Birth Weight less than 3000 grams in Indonesia reached 35.3% and in South Kalimantan 41.7%. This indicates an increase in the percentage of Birth Weight less than 3000 grams in South Kalimantan when compared to the 2018 Riskesdas data, the percentage of BW less than 3000 grams in South Kalimantan was 37.5%. This is a quantitative study using a cross-sectional research design and using secondary data from the SKI 2023. Data were analyzed univariately and bivariately with complex samples and chi square tests. The results of the study found a significant association between Birth Weight and Chronic Energy Deficiency (p-value = 0.001) where mothers with a history of Chronic Energy Deficiency had a 5 times higher risk. Conclusion: History of Chronic Energy Deficiency among mothers is an important determinant of infants’ Birth Weight in South Kalimantan. Further, these findings might contribute to the prevention strategy of Non-Communicable Diseases in South Kalimantan.
Co-Authors Agung Kurniawan Alifah Wulandari, Alifah Amirah, Fitria Angeline, Maharani Eria Anies Irawati Arumndari, Runi Asy'ari, Yudha Aulia, Bianda Aviria Ermamilia Basrowi, Ray Wagiu Darus, Febriansyah Dilantika, Charisma Ekasiwi, Firstya Diyah Erry Yudhya Mulyani Fadil Himawan, Muhammad Fathiyyah, Nurul Fatimah, Putri Ganisia, Ainun Hasanah, Fina Cahya Helmi, Tri Amelia Rahmitha Helmyati, Siti Henny Kurniati Imeldawati, Rakhmalia Izmi Arisa Putri Lubis Kania R, Rahayu Kartjito, Melissa Stephanie Kinesya, Edwin Kurnia Sari Kwarta, Cityta Putri Lily Arsanti Lestari Masita, Bertri Maulidya Mery Merlisia Mira Fauziah Mutiara, Nafisa Nadiyah Nadiyah Novianti, Anugrah Novitasari, Prihatini Dini Paramita, Farah Pascaramadhani, Addini Perkasa, Al Ilham Ksatria Gagah Pratiwi, Dessy Purnomosari, Lupi Putri Rahmadani, Putri Putri, Az-zahra Atika Putri, Febriani Ramadani, Okta Ryveka, Aurellia SARI, MIKE PERMATA Sari, Yona Wia Sartika Septiani, Seala Setyarsih, Liani Shidiqah, Raysah Sa’diyah Siti Arifah Pujonarti Suharti Supriyadi Taufik, Kumar Triyanti Triyanti Utami, Dessy Aryanti Winarno, Nibras Azeenshia Zahra, Audia Zakiudin Munasir Zata Ismah