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Aktivitas antioksidan ekstrak etanol daging buah rambutan hitam (Nephelium ramboutan-ake) dengan metode DPPH, ABTS dan FRAP: Antioxidant activity of rambutan hitam (Nephelium ramboutan-ake) flesh ethanol extract utilizing DPPH, ABTS, and FRAP methods Febrina, Lizma; Rusli, Rolan; Samsul, Erwin; Rusman, Arman; Setyowati, Widiastuti Agustina Eko
Bivalen: Chemical Studies Journal Vol. 8 No. 1 (2025)
Publisher : Bachelor Degree Program of Chemical Education - Mulawarman University | Program Studi S-1 Pendidikan Kimia - Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/bcsj.v8i1.4839

Abstract

Rambutan hitam atau maritam (Nephelium ramboutan-ake) merupakan tumbuhan tropis khas Kalimantan Timur. Tumbuhan ini tumbuh liar dihutan-hutan Kalimantan. Secara empiris, masyarakat setempat menggunakan buah rambutan hitam untuk pengobatan kanker. Namun demikian, penelitian ilmiah mengenai rambutan hitam masih sangat terbatas. Oleh karenanya, penelitian ini bertujuan untuk menganalisis aktivitas antioksidan dari buah rambutan hitam dengan menggunakan metode DPPH, ABTS, dan FRAP. Analisis aktivitas antioksidan dilakukan secara kolorimetri menggunakan spektrofotometer UV-Vis pada panjang gelombang tertentu. Hasil penelitian ini mengungkapkan bahwa ekstrak etanol daging buah rambutan hitam memiliki aktivitas antioksidan dengan kategori kuat baik dianalisis menggunakan metode DPPH (IC50 = 32,51 ± 0,21 mg/L), ABTS (IC50 = 30,04 ± 0,31 mg/L), dan FRAP (EC50 = 34,22 ± 0,17 mg/L). Aktivitas antioksidan yang kuat dari rambutan hitam menggambarkan potensi yang besar dari rambutan hitam dalam mengurangi dampak negatif radikal bebas. Adapun aktivitas antioksidan buah rambutan hitam dilaporkan pertama kali pada tulisan ini.
Workshop Pembuatan Gummy Candy Madu Kelulut Di Desa Bangun Rejo Kabupaten Kutai Kartanegara Samsul, Erwin; Junaidin, Junaidin; Rijai, Laode; Ibrahim, Arsyik; Herman, Herman; Rusli, Rolan; Ahmad, Islamudin; Febrina, Lizma; Farah, Harra Ismi; Hikmawan, Baso Didik; Rija’i, Hifdzur Rashif; Supriatno, Supriatno; Rusman, Arman; Almeida, Maria; Riki, Riki; Arifuddin, M; Bone, Mahfuzun; Arifian, Hanggara; Setiawaty, Agus
Journal of Community Research and Service Vol. 9 No. 2: July (2025)
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jcrs.v9i2.69839

Abstract

A workshop on making gummy candy based on stingless bee honey was held in Bangun Rejo Village, Kutai Kartanegara Regency, as an effort to empower the community through innovation in locally processed food products. The aim of this activity was to improve the skills of MSME actors and village residents in producing stingless honey gummy candy, and to elevate the added value of local honey. The methods used included a short theoretical session about the composition of stingless bee honey and the technical process of gummy candy production, a live demonstration, group practice among participants, as well as evaluation via pre-test and post-test on understanding and skills. The workshop was attended by 50 participants from various MSMEs and community groups. Results showed that after training there was an increase in participant understanding by approximately 75% compared to before the training. Furthermore, participants succeeded in making gummy candy with a chewy texture, the natural sweetness of stingless bee honey, and a distinctive aroma that was well accepted in organoleptic tests. This workshop made a tangible contribution to local product diversification, increasing production capacity, and the potential enhancement of village income through signature products based on stingless bee.
Pengaruh Konsumsi Produk Tanaman Biofarmasi Dalam Kemasan Dan Konsumsi Langsung Terhadap Manfaat Kesehatan Dan Manfaat Ekonomi, Serta Loyalitas Konsumen Junaidin, Junaidin; Hikmawan, Baso Didik; Rija'i, Hifdzur Rashif; Rusman, Arman
Jurnal Riseta Soshum Vol. 1 No. 2 (2024): J Riseta Soshum
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jrs.v1i2.6167

Abstract

Mengkonsumsi tanaman biofarmasi baik dalam bentuk kemasan atau mengkonsumsi secara langsung dari tanaman biofarmasi, ternyata menunjukkan  persepsi yang berbeda dalam hal manfaat kesehatan, manfaat ekonomi, dan loyalitas konsumen. Studi ini menggunakan Model Persamaan Struktural (SEM), dan menganalisis 301 responden. Hasil analisis membuktikan bahwa: Tidak ada pengaruh signifikan antara hubungan antara konsumsi tanaman biofarmasi yang dikemas terhadap manfaat kesehatan dan manfaat ekonomi, serta loyalitas konsumen. Terdapat hubungan yang signifikan antara konsumsi langsung tanaman biofarmasi terhadap manfaat kesehatan, manfaat ekonomi, dan loyalitas konsumen; Terdapat hubungan signifikan antara manfaat kesehatan dan manfaat ekonomi terhadap loyalitas konsumen. Hasil analisis juga membuktikan bahwa budaya masyarakat yang terbiasa mengonsumsi tanaman biofarmasi terbukti secara empiris.
An in Vitro Approach: Antibacterial Activity of Sansevieria trifasciata Prain. Leaves with Chemometric Analysis Kasmawati, Henny; Sida, Nurramadhani A.; Arfan, Arfan; Indrayanti, Wa Ode Dian; Rusman, Arman
Jurnal Sains dan Kesehatan Vol. 6 No. 1 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i1.2087

Abstract

Exploration the antibacterial activity of S.trifasciata Prain. is still limited, therefore this study aims to assess the antibacterial activity of extracts and ethyl acetate fractions of Sansevieria trifasciata Prain. The S.trifasciata leaves was macerated with ethanol 96%, then fractionated using the trituration method with ethyl acetate. The treatment group was divided into positive control group (PC) using ciprofloxacin, negative control (NC) using DMSO, extract, ethyl acetate fraction 5% (ET5%), 10% (ET10%), 20% (ET20%), 40% (ET40 %). Data were analyzed statistically by ANOVA and chemometrically with PCA. The inhibition zone for S.aureus bacteria in each sample is 26.69; 1.40; 23.32;2.82; 6.23; 11.11; 20.15 mm, respectively, E.coli is 26.65;0.63;22.65;3.61;7.11;11.44;21.15 mm respectively, P. aeruginosa is 27.40; 0.00; 23.23; 2.74;7.03;11.69;21.36 mm respectively. Percent inhibition of extract, ET5%, ET10%, ET20%, ET40% on S. aureus bacteria is 82.16; 5.31; 18.12; 36.39; 70.38% respectively, E.coli is 82.67; 11.13; 24.31; 40.56; 76.99% respectively, P. aeruginosa 84.85; 10.01; 25.65; 42.68; 77.98% respectively. Extract and ethyl acetate fraction have significant potential as antibacterial (p<0.05). The results of PCA chemometric analysis showed that the extract and ET40% had similar inhibition zone area to the positive control ciprofloxacin. The extract and the ethyl acetate fraction 40% are promising for development as antibacterials. Keywords:          Sansevieria trifasciata Prain., chemometric, bacterial
Metabolit Sekunder dan Uji Bioaktivitas Sitotoksik Ekstrak Buah Sumpit (Brucea javanica (L.) Merr) terhadap Artemia salina Leach Nur, Tajuddin; Rusman, Arman; Hikmawan, Baso Didik; Almaida, Maria; Herman; Ibrahim, Arsyik
Jurnal Riseta Naturafarm Vol. 1 No. 1 (2024): Jurnal Riseta Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/368zcy93

Abstract

Research carried out with the title of Secondary Metabolite Identification and bioactivity Fruit Extract Sumpit (Brucea javanica (L) Merr) to the shrimp larvae Artemia salina Leach. This study aims to identifying classes of secondary metabolites as well as test the bioactivity of secondary metabolites sumpit. Identifikasi fruit extracts performed to test the Chopsticks fruit extracts and fractions against reagent, while the bioactivity test was conducted using Brine Shrimp Lethality Test (BSLT). Data were analyzed using the method of Reed and Muench to get Lethality Concrentation value 50% (LC50). The results showed that the fruit extract Sumpit contain the alkaloid class of secondary metabolites, karatenoid, saponins, tannins, phenolic compounds, steroids, and terpenoids. Sumpit fruit bioactivity test results had LC50 values of the methanol extract of 3.10 ppm, n-hexane fraction of 2.09 ppm, 0.79 ppm ethyl acetate fraction and n-butanol fractions of 0.74 ppm.
Potential and Activities of the Sunscreen Lotion Preparation of Bawang Dayak (Eleutherine americana (Aubl.) Merr. by Ethanol Extract Fraction from East Boneo Ibrahim, Arsyik; Badawi, Satriani; Rusman, Arman; Riki; Samsul, Erwin; Sulistyarini, Riski; Arifuddin, M.; Ahmad, Islamudin
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 2 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/yrb89026

Abstract

Has conducted research Potential and Activities of the Sunscreen Lotion of Bawang Dayak (Eleutherine americana (Aubl.) Merr. by ethanol extract fraction from East Borneo. The purpose of the study was to determine the potency ann activity of the sunscreen ethanol extracts fraction of Bawang Dayak in the preparation of a lotion with the parameter measuring the percent transmission erythema (% Te) and pigmentation (% Tp) in vitro in the room temperature 27oC storage and accelerated temperature 40oC. Lotion dosage formulations using ethanol extracts fraction bawang Dayak with a concentration of 0.1% and 0.2%, and positive control is a trademark preparation Bless Sunscreen Lotion SPF 15®. Stages of research include the formulation and measurement of absorbance and value %Te) and %Tp at various storage temperatures with UV-Vis spectrophotometry at λ 292.5 to 372.5 nm. The analysis of research data using a program SPSS. The results showed that ethanol extract fraction concentration in lotion preparations of bawang Dayak 0.1% and 0.2% active as a sunscreen included in the category of sunblock. The extract fraction is active as a sunscreen and in the Sunbloc category, with the best concentration as a sunscreen being 0.2%, with its sunscreen potential not being significantly different from the control Sunscreen SPF 15® at the 5% level.
Formulation of Air Freshener Gel Combination of Mint Leaf Essential Oil (Mentha piperita L.) and Lemon (Citrus limon (L) Burm F.) Hafidzah, Nurul; Putri, Novita Eka Kartab; Almeida, Maria; Rusman, Arman; Herman, Herman
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 2 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/qds89550

Abstract

Air freshener gel is a semi-solid fragrance product that uses carrageenan and pectin as gel-forming components to overcome unpleasant odors when in a room with high temperatures. The purpose of this study was to determine the composition of carrageenan and pectin as gel-forming materials for air fresheners and the composition of the aroma comparison of mint oil (Mentha piperita L.) and lemon (Citrus limon (L) Burm F). The gel base was made with a ratio of carrageenan: pectin concentration of 1: 2; 1.8: 1.2; 2.5: 0.5 then the base was evaluated including organoleptic examination, stability test and gel hardness. The best base was then added with mint oil and lemon with a ratio of 1: 1.5; 1.25: 1.25; 1.5: 1 and the gel preparation was evaluated with organoleptic parameters, gel stability, gel hardness, liquid evaporation, fragrance resistance and hedonic test. The results of the study showed that the best base preparation after the evaluation of the base was a ratio of carrageenan: pectin concentration of 25: 0.5. Evaluation of the preparation with the addition of mint leaf oil (Mentha piperita L.) and lemon (Citrus limon (L) Burm F) to the base showed a value that was not too significant in the evaluation results. In the hedonic test, the formula with the addition of 2.5%: 2.5% mint leaf oil (Mentha piperita L.) and lemon (Citrus limon (L) Burm F) was the formula preferred by the panelists. So it can be concluded that the carrageenan and pectin combination room freshener gel with a concentration ratio of 2.5: 0.5% can be formulated as a base for room freshener gel preparations, namely producing a chewy and elastic gel base. The formulation of the most preferred combination of mint leaf essential oil and lemon oil as a gel fragrance is with a concentration of 2.5: 2.5%, because it produces a refreshing aroma
Alkaloid Profiling of Kadamba (Mitragyna speciosa Korth. Havil.) Leaves through Chromatographic Separation and UV-Vis Spectrophotometery Analysis Arifuddin, M.; Azmi, Fatur Rahman; Iswahyudi, Iswahyudi; Bone, Mahfuzun; Farrah, Harra Ismi; Arifian, Hanggara; Almeida, Maria; Rusman, Arman; Samsul, Erwin; Riki, Riki; Rija'i, Hifdzur Rashif; Hikmawan, Baso Didik; Junaidin, Junaidin; Febrina, Lizma; Rusli, Rolan; Ibrahim, Arsyik; Ahmad, Islamudin; Herman, Herman
Journal of Pharmaceuticals and Natural Sciences Vol. 2 No. 3 (2025): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jpns.v2i3.44

Abstract

Mitragyna speciosa Korth. berasal dari famili Rubiaceae yang banyak tumbuh di daratan negara-negara Asia Tenggara. Tumbuhan ini selain disebut Kratom, khususnya di daerah Kalimantan Timur dikenal juga dengan nama "Kadamba". Mitragyna speciosa Korth. belongs to the Rubiaceae family and is widely found in the mainland of Southeast Asian countries. This plant, known as Kratom, is also referred to as "Kadamba" in East Kalimantan. Kadamba has been used for generations as a traditional medicine and contains predominantly alkaloid compounds, which generally function as analgesics, antitussives, antidiarrheals, adrenergic agents, antimalarials, antibacterials, and antinociceptives. The aim of this research is to determine the isolation and identification methods for alkaloid compounds in Kadamba leaves. In this study, extraction was performed using methanol solvent, followed by fractionation using Vacuum Liquid Chromatography (VLC) and Column Chromatography (CC) with gradient eluents: 100% hexane, n-hexane : Ethyl Acetate (5:1, 1:1, 1:5), 100% Ethyl Acetate, Ethyl Acetate : Methanol (1:1, 1:5), and 100% Methanol. The compounds were then identified using Thin Layer Chromatography (TLC). The isolation process used preparative Thin Layer Chromatography (PTLC) with eluent n-hexane: ethyl acetate: 25% ammonia (6.5:3:0.5 v/v/v), and the spots were observed under UV light at 245 nm and 366 nm. The visible spots were sprayed with Dragendorff's reagent to identify the alkaloid compounds. The results showed that the UV-Vis spectrophotometric characterization of isolate B6-b had two peaks at wavelengths of 288 nm and 294 nm.
CLINICAL OBSERVATION OF MALONDIALDEHYDE FREE RADICAL COMPOUND LEVELS IN URINE SAMPLES OF SMOKERS AND NON SMOKERS GIVEN JUICE WATERMELON (Citrullus Lanatus) ZAMRUDDIN, NUR MASYITHAH; Dwi Septiani, Kadek Ayu; Almeida, Maria; Rusman, Arman; Jafar, Fahriani Istiqamah; Herman, Herman
Jurnal Farmasi Klinik dan Sains Vol 5, No 2 (2025): Jurnal Farmasi Klinik dan Sains
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Muhammadiyah Gombong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26753/jfks.v5i2.1933

Abstract

Malondialdehid (MDA) merupakan biomarker stres oksidatif akibat keberadaan radikal bebas dalam tubuh. Penelitian ini bertujuan untuk mengetahui gambaran kadar MDA urin dan asam urat pada responden perokok dan non perokok dan mengetahui perubahan kadar MDA urin dan asam urat pada responden perokok dan non perokok yang diberikan minuman antioksidan jus buah semangka (Citrullus lanatus). Metode penelitian yang digunakan adalah pre-post test design. Hasil penelitian menunjukkan bahwa kadar MDA urin pada perokok aktif dan bukan perokok sebelum pemberian jus semangka adalah 2,666 nmol/mL dan 1,506 nmol/mL, sedangkan hasil penelitian setelah pemberian jus semangka pada hari ke-7 pada responden adalah 0,799 nmol/mL dan 0,539 nmol/mL. Sedangkan kadar asam urat awal masing-masing responden sebesar 7,5 mg/dL dan 6,6 mg/dL dan hasil penelitian setelah pemberian jus pada hari ke-7 kepada responden sebesar 6,1 mg/dL dan 5,7 mg/dL. Pada hasil analisis statistik menggunakan uji-t didapatkan nilai p0,05 pada kadar asam urat perokok dan nilai p
Edukasi Beyond Use Date (BUD) kepada Masyarakat di Puskesmas Lempake Samarinda Samsul, Erwin; Sari, Indah Dewi; Pasaribu, Handayani; Mus, Nurul Muhlisa; Hikmawan, Baso Didik; Arifuddin, M.; Rusman, Arman; Riki, Riki; Bone, Mahfuzun; Herman, Herman; Junaidin, Junaidin; Febrina, Lizma; Ibrahim, Arsyik; Rijai, Hifdzur Rashif; Ahmad, Islamudin; Almeida, Maria; Rijai, Laode; Arifian, Hanggara
Sevanam: Jurnal Pengabdian Masyarakat Vol 5 No 3 (2026): Maret
Publisher : Universitas Hindu Negeri I Gusti Bagus Sugriwa Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25078/sevanam.v5i3.5684

Abstract

ABSTRACT There are still some people who do not understand the difference between the expiration date (Expired Date/ED) and the drug usage limit (Beyond Use Date/BUD). BUD is the time limit for drug use after compounding or after the primary packaging is opened. This activity aims to increase public knowledge, understanding, and awareness regarding the importance of paying attention to the safe limit for drug use or Beyond Use Date (BUD), so that people can use drugs wisely, safely, and responsibly. The activity implementation method includes counseling, material presentation, distribution of leaflets or brochures, and filling out pre-tests and post-tests. The number of participants who took part in this activity was 26 people. The results of the health promotion activity at the Lempake Community Health Center, Samarinda City showed that the average knowledge of participants about Beyond Use Date before providing education was 31.92%, and increased to 88.08% after being given information. Thus, it can be concluded that this activity was successful in increasing public knowledge regarding Beyond Use Date in the Lempake Community Health Center area, Samarinda City.. Key words: Beyond Use date (BUD), Expired date (ED), Lempake Health Center Samarinda City