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Muhammad Nurul Fadel
Universitas Muhammadiyah Kudus
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Journal : Jurnal Informatika dan Kesehatan

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Studi Analisa Kronofarmakologi Penggunaan Obat Ibuprofen pada Pasien Covid-19 di Rawap Inap RSUD Dr. Soedomo Trenggalek Fendy Prasetyawan; Yuneka Saristiana; Faisal Akhmal Muslikh; Ratna Mildawati; Chandra Arifin; Abd Rofiq; Emma Jayanti Besan; Muhammad Nurul Fadel; Charliandri Saputra Wahab; Muhammad Alviyan Shutiawan
Jurnal Informatika dan Kesehatan Vol. 1 No. 1 (2024): IKN : Jurnal Informatika dan Kesehatan
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ikn.v1i1.3024

Abstract

The global COVID-19 pandemic has presented unprecedented challenges to global health. The Dr. Soedomo Regional General Hospital in Trenggalek has been at the forefront of managing COVID-19 patients, with a primary focus on the use of ibuprofen to alleviate symptoms such as fever and pain. Despite the widespread use of ibuprofen, knowledge regarding its interaction with the circadian rhythm, especially in COVID-19 patients, remains limited. This study employed an analytical observational approach with a Cross-Sectional design to analyze the use of ibuprofen in COVID-19 patients at Dr. Soedomo Regional General Hospital in Trenggalek. The study included 100 patients, emphasizing body temperature at three different times. Data analysis revealed a significant decrease in body temperature after therapy, particularly at 4:00 PM. These findings lay the foundation for the development of more targeted and personalized treatment strategies by understanding the body's response patterns to therapy at different times.   Abstrak Pandemi global COVID-19 telah menciptakan tantangan kesehatan global yang belum pernah terjadi sebelumnya. Rumah Sakit Umum Daerah Dr. Soedomo di Trenggalek telah menjadi pusat perhatian dalam menangani pasien COVID-19. Fokus utama adalah penggunaan ibuprofen untuk mengelola gejala, seperti demam dan nyeri. Meskipun ibuprofen umum digunakan, pengetahuan tentang interaksi dengan siklus sirkadian tubuh, terutama pada pasien COVID-19, masih terbatas. Penelitian ini menggunakan pendekatan observasional analitik dengan desain Cross Sectional untuk menganalisis penggunaan ibuprofen pada pasien COVID-19 di RSUD Dr. Soedomo Trenggalek. Hasil penelitian melibatkan 100 pasien, dengan fokus pada suhu tubuh pada tiga waktu berbeda. Analisis data menunjukkan penurunan suhu tubuh yang signifikan setelah terapi, terutama pada pukul 16.00 WIB. Hasil ini memberikan dasar untuk pengembangan strategi pengobatan yang lebih terarah dan personalisasi, dengan memahami pola respons tubuh terhadap terapi pada waktu yang berbeda.
Co-Authors Abd Rofiq ABDUL ROKHMAN Adhimi, Cici Sayyidatul Ahmad Kholis Akbar Seno Syafriansyah Akhyasin Akhyasin Alya Narulita Andriyani, Yunita Arif Fahrudin Arif, Fahrudin Astutik, Widhi Besan, Emma Jayanti Besan, Ulfa Nabila Bintari Tri Sukoharjanti Chandra Arifin Chandra Arifin Charliandri Saputra Wahab Eko Retnowati Ema Jayanti Besan Emma Jayanti Besan Emma Jayanti Besan Endang Setyowati Endang Setyowati Endang Setyowati Fahrudin Arif Faisal Akhmal Muslikh Faisal Akhmal Muslikh Febriana, Laela Fendy Prasetyawan Firdyansyah, Diah Aprilia Fitri Apriliani Fransisca Dita Mayangsari Galih Kurniawan Gempita Hutami Dameria Hamzah, Hasyrul Hardiyani Presticasari Hasriyani Hasriyani Ika Mulyasari Ilhawa Zahra Imtiyaaz, Moh Thaariq Zelda Intan Adevia Rosnarita Intansari Setyaningrum Irawati Indrianingrum Irvan Shahrul Hidayat Izda Rahmawati Julia Megawati Djamal Kadir, Mujtahid Bin And Khudzaifi, Muhamad Lailatul Farikah Lathifatun Nida Noor M. Wahyu Ariawan Mega Putri Utami Mildawati, Ratna Muhamad Khudzaifi Muhammad Abdul Rozaq Muhammad Alviyan Shutiawan Muhammad Khudzaifi Muhammad Lathoiful Minan Muhammad Ridwanto Muhammad Zielal Askari Mustaanah, Aulia Nur Nanda Ardianto Negara, Sri Bintang Sahara Mahaputra Kusuma Nihayatus Sholekhah Nirmala Manik Nura Ali Dahbul Nurin, Eka Filza Nurul Huda Oktadiana, Isma Rahma, Siti Sofia Ratna Mildawati Rhomah, Eka Hayati Rika Wahyu Pujiastini Rofiq, Abd Rosnarita, Intan Adevia Sabaan, Wahid Sabila Febrianisa Safitri Ayuningsih Sakti, Aditya Sindu Salmasfattah, Novyananda Salsabila Khairunnisa savitri, Lisa Setianingsih, Elfrida Rosselly Siti Mutamimah, Siti Ulviani Yulia Husna Ummi Nurus Salamah Viren Ramadhan Wijaya, Nadela Wahyu Yuliasari, Aulia Wahyu Yulis Trinovitawati Yuneka Saristiana Zuhri, Mukhammad Syaifuddin