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All Journal Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Journal Of Nursing Practice Jurnal Surya Masyarakat Jurnal Kesehatan Islam : Islamic Health Journal Medical Technology and Public Health Journal Medical and Health Science Journal Community Development Journal Biomolecular and Health Science Journal Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang REMIK : Riset dan E-Jurnal Manajemen Informatika Komputer Community Development Journal: Jurnal Pengabdian Masyarakat BERNAS: Jurnal Pengabdian Kepada Masyarakat Jurnal Surya Masyarakat Indonesia Berdaya Darmabakti : Junal Pengabdian dan Pemberdayaan Masyarakat International Islamic Medical Journal Jurnal Kesehatan Tambusai Journal for Quality in Public Health
Salim, Hotimah Masdan
Universitas Nahdlatul Ulama Surabaya
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Antidepressant Effects of Mitragyna Speciosa Korth Extract on Diabetic Rats Putra, Reza Hery Mahendra; Awwaliyah, Evi Sylvia; Salim, Hotimah Masdan; Alam, Ilham Putera; Rofiq, Ainul
Jurnal Ilmu Kesehatan dan Kesehatan Vol 8 No 02 (2024): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v8i02.5919

Abstract

Background: Diabetes mellitus is most common associated with neurological complications, including depressive symptoms, so this study investigated whether mitragyna may provide benefits in reducing depressive symptoms in animal models of diabetes. This study aims to evaluate the effect of mitragyna as a potential antidepressant agent in animal models of diabetes mellitus using the Force Swimming Test (FST). Methods: In this study, diabetes mellitus rats were induced by administering streptozotocin and then divided into four groups: control group (Control), Group Diabetes (DM), Mitragyna treatment group (DM+EMS 15mg) and (DM+EMS 30mg). After the treatment period, the rats were then tested with the FST, which is used to measure immobility behavior which can be used as an indicator of depressive symptoms. Results: The results showed that the treatment group that received mitragyna showed shorter immobility times compared to the control group (P<0.01), indicating an increased active response in facing FST stressors. Conclusion: These results indicate that mitragyna has potential as an antidepressant agent in reducing depressive symptoms in rats models of diabetes mellitus.
Atypical Presentation of Multiple Myeloma: From Heart Failure to Multiple Myeloma Sohaimi, Ainur Elliana; Jamhuri, Nur Syazwani; Ibrahim, Ismail; Salim, Hotimah Masdan
Jurnal Ilmu Kesehatan dan Kesehatan Vol 8 No 02 (2024): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v8i02.6068

Abstract

Multiple myeloma (MM) is a hematological malignancy commonly associated with bone pain, hypercalcemia, and renal failure. However, its presentation can occasionally mimic other medical conditions, which may delay diagnosis. This case report describes a patient who was initially diagnosed and treated for heart failure but was later found to have MM, highlighting the importance of considering MM in the differential diagnosis of heart failure. A 56-year-old lady presented with recurrent episodes of shortness of breath, orthopnea, paroxysmal nocturnal dypsnea and bilateral lower limb swelling which she had been treated for decompensated heart failure with optimal therapy. She denied any family history of cardiovascular disease personal history of underlying medical condition and was a nonsmoker. This patient was diagnosed with multiple myeloma and probability of concomitant cardiac amyloidosis and commenced on bortezomib, thalidomide and dexamethasone (VTD) regime and standard optimal therapy of heart failure but her condition deteriorated. After a few days of starting chemotherapy, patient demised despite all the resuscitative effort. Multiple myeloma is common hematological malignancy with its distinct clinical features of “CRAB”, however, more attention and alertness should also be exercised by clinicians as to be able to diagnose it early.
Evaluation of The Rate of Microbial Activity in Coconut (Cocos Nucifera L.) Milk When Stored at Different Time Intervals EBISINTEI, PRECIOUS; Salim, Hotimah Masdan
Jurnal Medis Islam Internasional Vol 6 No 2 (2024): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v6i2.6480

Abstract

Introduction: Coconut milk is a very nutritional milk or drink. The processor of coconut into milk using various forms has been A serious risk and health hazard.Objective: This study aims to describe or evaluate the rate of microbial activity in coconut milk when stored.Methods: The coconut milk was extracted from the coconut meat using an aseptic technique.Results: The initial PH value was 6.10, it was observed that fermentation started from the 12th hour, and at the 24th hour, the PH of the coconut milk was 4.48. After 48 hours, the pH was 4.20 and at the 72nd hour time, the pH value was 3.99. It was also observed that the 24 hours stored coconut milk sample has the highest Bacterial growth rate of 4.12 × 102 and a fungal growth rate of 1.2 × 102.Conclusions: Biochemical test carried out on the bacterial isolate showed Bacillus spp, Staphylococcus aureus, and Bifidobacterium bifidum were observed to be present at 24 hours and 48 hours of the coconut milk sample and at the 72nd hours of the coconut milk sample Pseudomonas spp, Lactobacillus spp, and Aeromonas caviae were observed to be present. A drop of pH value to 3.99 at the 72nd hour was observed due to the activity of Lactobacillus spp
Pemberdayaan Santri Untuk Meningkatkan Pemahaman Tentang Perilaku Hidup Bersih dan Sehat (PHBS) di Pondok Pesantren Bustanul Ulum Syafiuddin, Achmad; Iswahyudi, Iswahyudi; Wikurendra, Edza Aria; Salim, Hotimah Masdan; Asih, Akas Yekti Pulih; Zuhdi, Ubaidillah; Yanti, Alfiyah Indah; Fatmawati, Ulik
Darmabakti : Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 5 No 02 (2024): Darmabakti : Jurnal Pengabdian dan Pemberdayaan Masyarakat
Publisher : Lembaga Peneliian dan Pengabdian Masyarakat (LPPM) Universitas Islam Madura (UIM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31102/darmabakti.2024.5.02.312-320

Abstract

Pondok Pesantren adalah bentuk lembaga pendidikan keagamaan yang tumbuh dan berkembang dari oleh dan untuk masyarakat yang berperan penting dalam pengembangan sumber daya manusia, diharapkan para santri dan para pemimpin serta pengelola pondok pesantren, tidak saja mahir dalam aspek pembangunan moral dan spiritual dengan intelektual yang bernuansa agamis, namun dapat pula menjadi motor penggerak, motivator dan inovator dalam pembangunan kesehatan. Pengabdian masyarakat ini bertujuan untuk meningkatkan pemahaman tentang penerapan PHBS di Pondok Pesantren Tradisional Bustanul Ulum Pamekasan. Pondok Pesantren Bustanul Ulum Pamekasan dipilih sebagai model pesantren yang berada di Desa Sumber Anom dan merupakan salah satu pesantren tradisional yang masih mengalami masalah terkait PHBS untuk santri. Hasil kuesioner menunjukkan bahwa 93,15% santri belum menggunakan air bersih untuk kebutuhan sehari-hari, serta 80.82% santri belum mengelompokkan sampah organik dan anorganik. Pengabdian masyarakat ini dilakukan melalui dua tahap yaitu (i) Sosialisasi tentang penggunaan air bersih dan 6 langkah cuci tangan dengan baik dan (ii) Melakukan sosialisasi dan demonstrasi metode pengelolaan sampah organik dan anorganik untuk memberikan edukasi terkait cara memilah dan mengolah sampah yang tepat. Secara umum, pemahaman santri tentang tentang PHBS air bersih dan pengolahan sampah meningkat setelah dilakukan sosialisasi dan demonstrasi. Pengukuran pengetahuan dari sosialisasi dan demonstrasi menunjukkan peningkatan pengetahuan sebesar 16,16% dari sebelum diadakannya sosialisasi dan demonstrasi.
Skrining Pencegahan Penularan TBC (SiGaP-TBC) di Pondok Pesantren Hidayatulloh Al-Muhajirin, Bangkalan Salim, Hotimah Masdan; Mulyadi, Mulyadi; Prasetya, Dwi Arman
Darmabakti : Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 6 No 01 (2025): Darmabakti : Junal Pengabdian dan Pemberdayaan Masyarakat
Publisher : Lembaga Peneliian dan Pengabdian Masyarakat (LPPM) Universitas Islam Madura (UIM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31102/darmabakti.2025.6.01.44-51

Abstract

Pondok Pesantren Hidayatullah Al-Muhajjirin accommodates approximately 500 male and female students aged 14 to 18, offering education at the Madrasah Tsanawiyah and vocational high school (SMK) levels. Given the diverse backgrounds of these students, their awareness of Clean and Healthy Living Behavior (PHBS) varies, impacting efforts to prevent airborne diseases like tuberculosis (TB). To address this, a community service initiative introduced the SiGaP-TBC program, aiming to enhance knowledge about TB transmission and promote self-screening. Methods included educational sessions, health screenings, utilization of the SiGaP-TBC application for self-assessment, and training in food self-sufficiency through healthy gardening. The program led to increased student awareness of PHBS in TB prevention, the establishment of student health cadres within the pesantren's health management system, and improved self-screening capabilities using the SiGaP-TBC app. In conclusion, the SiGaP-TBC program effectively fosters self-reliance in TB infection prevention and health empowerment within the pesantren community.
Analysis Of The Effect Of Hyperbarics On Reducing Blood Sugar And Wound Healing Phase In DM Patients : Systematic Review Wiratama, Rahardyan Dika; Abdul Muhith; Hotimah Masdan Salim; Siti Nur Hasina
Journal for Quality in Public Health Vol. 8 No. 1 (2024): November
Publisher : Master of Public Health Program Institut Ilmu Kesehatan STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/jqph.v8i1.506

Abstract

Diabetes Mellitus (DM) ranks fifth as a cause of death, Diabetes Mellitus (DM) is a deadly disease after coronary disease, stroke, cardiovascular contamination disease, and respiratory disease. Diabetes Mellitus is an infectious disease that proliferates continuously, usually the side effects are not distinguished because the side effects appear mild such as weakness, wounds that do not heal, and polyuria. The purpose of this study was to determine the effect of hyperbaric on blood sugar reduction and wound healing phase of DM patients. The method used in this study is systematic review with systematic review (PRISMA) using several journal databases from Google Scholar, Science Direct, and Pubmed from 2019-2024 with the keywords "Diabetes Mellitus", "Hyperbaric", "Decrease in blood sugar levels ”, “wound healing phase of DM patients”. 10 articles were ready to be reviewed 10 articles were obtained with PRISMA. The results of the systematic review study showed that there was an effect of hyperbaric administration on reducing blood sugar levels and the wound healing phase of patients with DM. It is hoped that hyperbaric therapy will prevent complications from DM disease.
The Effect of Mirror Therapy on Exterm Muscle Strength in Non-Hemorrhagic Stroke Patients Based on Self Care Theory Siti Robi’atus Sholiha; R. Khairiyatul Afiyah; Hotimah Masdan Salim; Abdul Muhith; Siti Nur Hasina
Journal Of Nursing Practice Vol. 8 No. 3 (2025): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/jnp.v8i3.661

Abstract

Background: Non-hemorrhagic strokes result in neuromuscular disorders with reduced activity and weakness in joint movement and even disability. This condition receives treatment at the hospital in the form of educational therapy, diet, medication and ROM (active and passive). Purpose: The aim of the research was to determine the effect of Mirror Therapy on extremity muscle strength in non-hemorrhagic stroke patients based on self-care theory. Methods: Quasi experiment research design with a pretest posttest approach with control group design. The population of all non-hemorrhagic stroke patients with a sample size of 40 people, divided into 2 groups, namely the control group and the intervention group, was selected using a purposive sampling technique. The instruments used in this research include respondent characteristics, MMT (Manual Muscle Testing) observation sheets and Mirror Therapy SOP. Data analysis used the Mann Whitney U-test with a significance value of P value < 0.05. Results: The results of the study showed that the average muscle strength score in the Mirror Therapy intervention group was 1.55 before and after 2.65, while in the control group with standard hospital treatment before 1,40 and after 1.95. The Wilcoxon Test results show P value = 0.000 in the intervention group and P value = 0.000 in the control group, meaning there is an increase in extremity muscle strength in the intervention and control groups. Based on the Mann Whitney test, it shows P value = 0.013, meaning there is no differences in Mirror Therapy on extremity muscle strength in non-hemorrhagic stroke patients. Conclusion: The application of Mirror Therapy affects the level of extremity muscle strength in non-haemorrhagic stroke patients. Nurses are expected to be able to apply Mirror Therapy to apply it in nursing practice.
The Role Of Mitragyna speciosa (Korth) As An Anti-Inflammatory Agent In Wound Healing In Living Cells Ferdinan Hanafi, Eka Satria Akbar; Pramesti, Rosandhy Alfiyah; Jazuli, Muhammad Aqil Siroj; Rihhadatulays, Khuzaimah Nur Juhanifah; Salim, Hotimah Masdan; Savitri, Ardyarini Dyah
Jurnal Ilmu Kesehatan dan Kesehatan Vol 9 No 1 (2025): FEBRUARY : Fragmentation In Modern Healthcare Approaches Amid Rising Chronic And
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v9i1.7994

Abstract

Background: Wound is a condition in which the integrity of body tissue is disrupted, leading to the activation of a complex biological process known as wound healing. This process aims to restore the protective skin barrier, prevent infection, and minimize fluid loss. It involves sequential phases of hemostasis, inflammation, proliferation, and remodeling. While inflammation is essential for initiating repair, prolonged or excessive inflammation may delay the healing process. Mitragyna speciosa (Korth) is a medicinal plant traditionally used in various cultures and has been reported to exhibit multiple pharmacological properties, including anti-inflammatory, antioxidant, antibacterial, analgesic, and wound-healing activities. Methods: The present systematic review was conducted to identify and synthesize scientific evidence regarding the potential of Mitragyna speciosa extract as a therapeutic agent in wound healing through anti-inflammatory and other biological pathways. Literature searches were performed in ScienceDirect, PubMed, MDPI, DOAJ, and Google Scholar following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Results :A total of 1,176 studies were screened, and five experimental studies fulfilled the inclusion criteria. The findings consistently demonstrated that Mitragyna speciosa extract suppressed pro-inflammatory mediators such as nitric oxide, reactive oxygen species, tumor necrosis factor-alpha, interleukin-6, and enzymatic pathways including cyclooxygenase-2 and 5-lipoxygenase. In addition, the extract stimulated cell migration, endothelial migration, and angiogenesis, thereby supporting tissue regeneration. Toxicity profiles suggest that the extract is safe at effective concentrations, although responses remain dose-dependent. Conclusions: Overall, Mitragyna speciosa shows promise as a plant-based therapeutic option for wound healing. Nevertheless, current evidence is limited and largely derived from in vitro studies, indicating the need for more extensive in vivo and clinical investigations.
Penerapan Sarana Sehat dan Sistem Filtrasi Sederhana untuk Mentransformasi Pesantren Hidayatun Najah Menjadi Bersih dan Sehat Syafiuddin, Achmad; Wikurendra, Edza Aria; Salim, Hotimah Masdan; Putri, Endah Budi Permana; Garfansa, Marchel Putra; Iswahyudi, Iswahyudi; Ekalaturrahmah, Yenni Arista Cipta
Darmabakti : Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 6 No 02 (2025): Darmabakti : Junal Pengabdian dan Pemberdayaan Masyarakat
Publisher : Lembaga Peneliian dan Pengabdian Masyarakat (LPPM) Universitas Islam Madura (UIM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31102/darmabakti.2025.6.02.213-219

Abstract

Pondok pesantren (PP) Hidayatun Najah untuk memenuhi kebutuhan air bersih diperoleh dari air sungai yang berada di sekitar pondok pesantren. Namun, upaya ini masih belum mampu untuk memenuhi kebutuhan air bersih tersebut serta santri belum mengetahui dampak penggunaan air serta lingkungan yang kotor bagi kesehatan. Kegiatan pengabdian ini bertujuan untuk memberikan pelatihan dan edukasi tentang pentingnya air bersih untuk kesehatan. Kegiatan ini juga memberikan pemahaman dan penggunaan teknologi pemurnian air, kegiatan pengabdian ini akan fokus pada introduksi dan penerapan sistem filtrasi pasir lambat. Metode wawancara digunakan untuk menggali pemahaman dan tanggapan santri terhadap materi yang disampaikan. Pelatihan ini memberikan dampak positif yang signifikan, termasuk peningkatan kualitas air yang memenuhi standar baku mutu air minum, serta peningkatan pengetahuan dan kesadaran santri tentang pentingnya menjaga kebersihan air. kegiatan ini juga membangun struktur organisasi Kadarsih yang melibatkan santri dalam pengelolaan kebersihan lingkungan secara lebih sistematis dan berkelanjutan.
Effects of Kratom (Mitragyna speciosa) Hydrogel Application on Pancreatic Histopathology in Type 2 Diabetic Mice Muhammad Aqil Siroj Jazuli; Ismail, Zainul Hadi Wildan; Rihhadatulays, Khuzaimah Nur Juhanifah; Hanafi, Eka Satria Akbar Ferdinan; Jinan, Puspita Rahmatul; Pramesti, Rosandhy Alifyah; Salim, Hotimah Masdan; Bintarti, Tri Wahyuni
Jurnal Ilmu Kesehatan dan Kesehatan Vol 9 No 2 (2025): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v9i2.8018

Abstract

Background: Type 2 diabetes mellitus is a metabolic disorder characterized by elevated blood glucose caused by insulin resistance and impaired insulin production by pancreatic β-cells due to oxidative stress. Kratom (Mitragyna speciosa) has been widely investigated for its antidiabetic, anti-inflammatory, and antioxidant effects, attributed to its alkaloid, flavonoid, phenolic, and saponin contents. This study aimed to evaluate the potential of topical kratom hydrogel as an innovative approach to improving pancreatic histology in type 2 diabetic mice, which has not been previously reported. Methods: Fifteen mice were divided into three groups: untreated diabetic group (DM), diabetic group treated with 5% kratom hydrogel (K5), and diabetic group treated with 15% kratom hydrogel (K15). Treatments were administered for two weeks. Parameters assessed included the percentage of healthy β-cells and acinar cells, as well as histological scoring of islet damage. Data were analyzed using parametric or non-parametric tests according to the normality distribution of each parameter. Results: Administration of 5% kratom hydrogel significantly increased the percentage of healthy β-cells (p<0.05) compared with 15% kratom hydrogel, which unexpectedly showed a lower proportion of healthy cells than the untreated group. Interestingly, the higher dose appeared to exert more toxic effects, whereas the lower dose provided better protective effects. No significant differences were observed in acinar cell parameters or islet damage scores, possibly due to the limited sample size. Conclusion: These findings provide preliminary evidence supporting the systemic therapeutic potential of topical kratom hydrogel, particularly in determining the effective dose and the need for larger sample sizes to obtain more consistent outcomes.
Co-Authors A., Ratna Ariesta Dwi Abdul Muhith Achmad Hilman Fahmy Aditya Bhayusakti Adyan Donastin Afiyah, R. Khairiyatul Akas Yekti Pulih Asih Alam, Ilham Putera Alam, Ilham Putra Algristian, Hafid Andi Roesbiantoro Andreas Putro Ragil Santoso, Andreas Putro Ragil Anggraini, Yasi Ardianti, Ami Awwaliya, Evi Awwaliyah, Evi Sylvia Awwaliyah, Evy Silvia Bagas Setiawan Ihsan Zaini Bagas Setiawan Ihsan Zaini Bintarti, Tri Wahyuni Bintarti, Tri Wahyuni Choirotussanijah Choirotussanijah Choirotussanijjah Danny Irawan David Sajid Muhammad Dayu Satriya Wibawa Deny Febriwijaya Romadhani Desi Irawati, Adinda Devyana Dyah Wulandari Dwi Arman Prasetya Dwimantoro EBISINTEI, PRECIOUS Edza Aria Wikurendra Endah Budi Permana Putri Erfina Miftakhul Zannah Evi Octavia Djamaludin Fatmawati, Ulik Ferdinan Hanafi, Eka Satria Akbar Fifi Khoirul Fitriyah Garfansa, Marchel Putra Hanafi, Eka Satria Akbar Ferdinan Handayani Handayani Handayani, Nanik HAQUE, ZAMIRAH MABARROH EL Ika Mardiyanti Ilham Putera Alam Ilham Putra Alam Ima Kurniastuti Ismail Ibrahim Ismail, Zainul Hadi Wildan Iswahyudi Iswahyudi ISWAHYUDI ISWAHYUDI Izki Masyaqqoni Pujiana Jamhuri, Nur Syazwani Jazuli, Muhammad Aqil Siroj Jessica Puspa Kencana Jinan, Puspita Rahmatul Karina Dwiyanti Kencana, Jessica Puspa Lea Maera Shanty Lintan Farizqi Kurnia Lysa Veterini Maria Ulfa Marinda Dwi Puspitarini Marselli Widya Lestari Michio Shimabukuro Muhammad Aqil Siroj Jazuli Muhammad, David Sajid Muhammada, Davida Sajid Mukhtar Adi Nugroho Muliani, Nurlina Mulyadi Mulyadi Nadia Nisaussholihah Nahdatien, Ima Nanik Handayani Nisaussholihah, Nadia Novera Herdiani, Novera Nur Azizah AS Pramesti, Rosandhy Alfiyah Pramesti, Rosandhy Alifyah Puspitasari, Renny Novi Putra, Reza Hery Mahendra R.A. Hani Faradis Ratna Ariesta Dwi Andriani Reza Mahendra Rihhadatulays, Khuzaimah Nur Juhanifah Rofik, Ainul rofiq, ainul Romadhani, Deny Febriwijaya Rosda Rodhiyana Savitri, Ardyarini Dyah Siti Nur Hasina Siti Robi’atus Sholiha Sohaimi, Ainur Elliana Sonny Edbert Syafiuddin, Achmad Tri Deviasari Wulan Tri Wahyu Bintarti Ubaidillah Zuhdi Widya Dio Kharisma Wiratama, Rahardyan Dika Yanti, Alfiyah Indah Yasi Anggraini Yenni Arista Cipta Ekalaturrahmah Yuani Setiwati Zannah, Erfina Miftakhul