Article Per Year (5 Year)
p-Index From 2021 - 2026
7.059
P-Index
This Author published in this journals
All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Kesehatan Andalas Global Medical and Health Communication Biomedical Journal of Indonesia Window of Health : Jurnal Kesehatan Collaborative Medical Journal (CMJ) Bioscientia Medicina : Journal of Biomedicine and Translational Research Health and Medical Journal Human Care Journal Andalas obstetrics and gynecology journal Jurnal Ners Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Kesehatan Indonesia (JIKSI) The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Journal of Pharmaceutical and Sciences. Jurnal Otorinolaringologi Kepala dan Leher Indonesia (JOKLI) Neurona Jurnal Sains Farmasi dan Kesehatan Jurnal Sains, Teknologi dan Kesehatan
Restu Susanti
Departemen Neurologi, Fakultas Kedokteran, Universitas Andalas
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary

Published : 75 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 75 Documents
Search

 4   5   6   7   8 
Hubungan Kadar Neuron Specific Enolase Serum dengan Subtipe dan Tingkat Keparahan pada Pasien Stroke Iskemik Akut Dhani Arief Prandana; Syarif Indra; Dedi Sutia; Restu Susanti; Fanny Adhy Putri; Gunawan Septa Dinata
Jurnal Ners Vol. 9 No. 4 (2025): OKTOBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i4.49867

Abstract

Background: Acute ischemic stroke is a serious medical condition with potentially life-threatening consequences. It occurs when cerebral blood flow is obstructed by vascular occlusion, resulting in brain tissue injury. Neuron Specific Enolase (NSE) is a biomarker used to assess the extent of neuronal damage in patients with ischemic stroke. This study aims to evaluate the association between serum NSE levels, stroke subtypes, and stroke severity in patients with acute ischemic stroke. Methods: This observational study employed a cross-sectional design and included 67 patients with acute ischemic stroke. Serum NSE levels were measured using the ELISA method. Stroke subtypes were determined according to the TOAST classification, and stroke severity was assessed using the NIHSS score. Statistical analysis was performed to evaluate the association between serum NSE levels, stroke subtypes, and severity. Results: The mean serum NSE level was 14.038 ng/ml. Large artery atherosclerosis (LAA) was the most prevalent subtype with a moderate severity level. Statistical analysis showed a significant association between serum NSE levels and stroke subtype (p = 0.021) and severity (p = 0.034) in patients with acute ischemic stroke. Conclusion: Serum NSE levels are significantly associated with both stroke subtype and severity in patients with acute ischemic stroke.
The Relationship Between Serum Calprotectin Levels and Severity in Myasthenia Gravis Patients at Dr. M. Djamil Hospital Padang Novia Riza Lestari; Lydia Susanti; Yuliarni Syafrita; Restu Susanti; Reno Bestari; Dedi Sutia
Jurnal Ners Vol. 10 No. 1 (2026): JANUARI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i1.51684

Abstract

Myasthenia Gravis (MG) is an autoimmune disorder characterized by skeletal muscle weakness resulting from impaired neuromuscular transmission, primarily caused by autoantibodies directed against acetylcholine receptors. Excessive immune activation in MG triggers the release of inflammatory mediators, one of which is calprotectin — a protein complex of S100A8/A9 that is released by neutrophils and monocytes during the inflammatory process. Elevated levels of calprotectin have been reported in various autoimmune diseases; however, the relationship between serum calprotectin concentration and disease severity in MG, based on the Myasthenia Gravis Foundation of America (MGFA) classification, has not been extensively investigated. The objective of this study was to determine the association between serum calprotectin levels and disease severity in patients with MG. This study employed a cross-sectional design involving 23 MG patients receiving treatment at Dr. M. Djamil Hospital, Padang, from May to July 2025. Serum calprotectin levels were measured using the ELISA method, while MG severity was assessed using the MGFA scoring system. Statistical analyses were performed using SPSS version 27.0, with a significance level set at p < 0.05. The results of this study showed that serum calprotectin levels in patients with Myasthenia Gravis (MG) tended to be higher than in the healthy population; however, there was no significant association with the Myasthenia Gravis Foundation of America (MGFA) severity classification (p = 0.276).
Hubungan Kadar Glial Fibrillary Acidic Protein Serum dengan Skor Nihss dan Ich Score pada Pasien Stroke Hemoragik Dicky Lesmana; Syarif Indra; Restu Susanti; Yuliarni Syafrita; Dedi Sutia; Lydia Susanti
Jurnal Ners Vol. 10 No. 1 (2026): JANUARI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i1.54075

Abstract

Hemorrhagic stroke, particularly intracerebral hemorrhage (ICH), is a major cause of mortality and morbidity and is associated with poorer outcomes than ischemic stroke. The severity of ICH is commonly assessed using the National Institutes of Health Stroke Scale (NIHSS) and the ICH score. Glial fibrillary acidic protein (GFAP) is an astrocytic protein released into the circulation as a result of glial tissue injury and is known to be elevated in various types of stroke, with generally higher concentrations in ICH. This study aimed to evaluate the potential of GFAP as an indicator of disease severity and clinical outcomes in ICH. This was an observational analytic study with a cross-sectional design conducted in patients with hemorrhagic stroke hospitalized at RSUP Dr. M. Djamil Padang from February to July 2025. Serum GFAP levels were measured using the ELISA method, while disease severity and mortality were assessed using the NIHSS and ICH score. Statistical analysis was performed using one-way ANOVA or the Kruskal–Wallis test to examine the relationship between GFAP and NIHSS, and Pearson or Spearman correlation tests to evaluate the relationship between GFAP and the ICH score. Most subjects had moderate stroke severity based on the NIHSS (48.57%). The median serum GFAP level was 3.41 ng/mL (1.75–17.7). Analysis showed a significant difference in GFAP levels across the three NIHSS severity categories (p = 0.001), particularly between the mild–severe (p = 0.002) and moderate–severe (p = 0.001) groups. Spearman correlation analysis demonstrated a significant positive correlation between GFAP levels and the ICH score (p = 0.000; r = 0.481). In addition, GFAP levels were significantly higher in patients with hemorrhage volumes >30 cc compared with those ≤30 cc (median 7.29 vs 3.24 ng/mL; p = 0.000). Serum GFAP levels were significantly associated with NIHSS score, ICH score, and hemorrhage volume in patients with hemorrhagic stroke. These findings support the use of GFAP as a biomarker for assessing severity and prognosis in hemorrhagic stroke.
FAKTOR YANG BERHUBUNGAN DENGAN KELUHAN INSOMNIA PADA MAHASISWA PROGRAM STUDI PENDIDIKAN DOKTER Wijaya, Claudia Novi; Susanti, Restu; Usman, Elly
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 1 No. 4 (2024): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Desember 2024
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/nf07b868

Abstract

Mahasiswa rentan menderita insomnia akibat perubahan pola tidur saat memasuki perguruan tinggi dan meningkatnya stres akibat perubahan tuntutan sosial dan akademik. Oleh karena itu, perlu diketahui faktor-faktor yang berhubungan dengan insomnia untuk mengetahui faktor-faktor yang dapat dimodifikasi dalam pengendalian keluhan insomnia pada mahasiswa. Penelitian ini menggunakan desain penelitian analitik dengan pendekatan cross-sectional dan teknik pengambilan sampel proportional stratified simple random sampling. Penelitian ini dilaksanakan selama bulan Oktober 2021 sampai dengan Juni 2022 di Pendidikan Dokter Fakultas Kedokteran Universitas Andalas dengan jumlah sampel sebanyak 71 orang. Mahasiswa Pendidikan Dokter sebagian besar (63,4% atau 45 orang) mempunyai keluhan insomnia. Hasil uji statistik menunjukkan tidak ada hubungan jenis kelamin (p=1,00), kebiasaan merokok (p=0,398), konsumsi kopi (p=0,127), lama penggunaan gadget (p=0,617), dan sleep hygiene (p=0,183) dengan keluhan insomnia. Masih tingginya frekuensi keluhan insomnia pada mahasiswa Pendidikan Kedokteran. Oleh karena itu, perlu dilakukan penelitian lebih lanjut untuk mengkaji faktor risiko lain yang berhubungan dengan keluhan insomnia
HUBUNGAN KADAR UREUM DAN KREATININ SERUM DENGAN FUNGSI KOGNITIF PENDERITA PENYAKIT GINJAL KRONIK Adzra Fadhila Iswan; Restu Susanti; Dian Pertiwi; Lydia Susanti; Almurdi Almurdi; Miftah Irramah
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 3 No. 2 (2026): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Juni 2026 (In Press)
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v3i2.2596

Abstract

Chronic Kidney Disease (CKD) may lead to various complications, including cognitive impairment. The causative factor is the toxic substances accumulation in the body, including serum ureum and creatinine. This study aimed to determine the relationship between serum ureum and creatinine levels with cognitive function in CKD patients. Samples were taken using a consecutive sampling technique on 46 CKD patients who were hemodialyzed at RSUP Dr. M. Djamil Padang. Cognitive function was assessed using the Montreal Cognitive Assessment Indonesian version (MoCA-Ina). Serum ureum and creatinine were measured with a spectrophotometer. Data were analyzed using the Chi-Square test. Results showed that CKD patients with cognitive impairment were more likely to be older than 50 years old (54.2%) and male (58.3%), had at least a high school education and above (70.8%), were accompanied by hypertension (75%), and without diabetes mellitus (91.7%). The median serum ureum and creatinine levels in patients with cognitive impairment were 124 mg/dL and 10.05 mg/dL. The relationship between serum ureum and creatinine levels with cognitive function had a 0.039 and 0.768 p-value. There is no relationship between the characteristics of the sample, including age, gender, education level, hypertension, and diabetes mellitus with cognitive function in CKD patients. There is a significant relationship between serum ureum levels and cognitive function, but a non-significant relationship between serum creatinine with the cognitive function of CKD patients.
Co-Authors Abdi, Tri Jaya Abdillah, Tegar Adzra Fadhila Iswan Afriani, Nita Afriwardi Afriwardi Afriyeni Sri Rahmi Akmal Irsyadi Iswan Almurdi Almurdi Anggrainy, Fenty Arina Widya Murni ATTIYA ISTARINI Aulia Noza Darwin Amir, Darwin Dea Rika Putri Purba Dedi Sutia Dedi Sutia Dhani Arief Prandana Dian Pertiwi Dian Pertiwi Alty Dicky Lesmana Eldi Sauma Eryati Darwin Eva Decroli Fanny Adhy Putri Fanny Adhy Putri Gunawan Septa Dinata Gusti Revilla Hanny Vidya Sari Harun Harnavi Hasmiwati Hendra Permana Hendra Permana Hirowati Ali Hirowati Ali, Hirowati Husna Yetti Husni Minanda Fikri Ida Rahmah Burhan Ilahi, Fitratul Indra, Syarif Isnindiah Koerniati Isnu Lucky Riandini Isnu Lucky Riandini, Isnu Lucky Istiqomah Kurniawan, Yoga Setia Lenny Arinda Lesti Marliana Lydia Susanti Lydia Susanti Lydia Susanti, Lydia Melda Yelmaiza Miftah Irramah Musrizal Adli Nabila Priscilla Putri Nada Utami Prahastiwi Nailatul Fadhilah Nita Afriani Novia Riza Lestari Nur Indrawaty Lipoeto Priyanka Prima Putri Putra, Syandrea Prima Putri, Azhara Dhiya Yosse Putri, Fanny Adhy Putri, Nabila Priscilla Rachmat Saleh Eka Putra Reno Bestari Reno Bestari Ridho Ahmad Jabbar Rifki Irsyad Rika Susanti Rizki Muhammad Rananda Rudy Afriant Salsabilah Firdausiah Saptino Miro Selfi Renita Rusjdi Sukri Rahman Syamel Muhammad Syarif Indra Syarif Indra Syarif Indra Syarif Indra Tiara Mardalifa Tofrizal Tofrizal Tofrizal Ulya Uti Fasrini Umul Khair Wijaya, Claudia Novi Yoga Setia Kurniawan Yolanda, Meuthia Yulia Trisna Yuliarni Syafrita Yuliarni Syafrita Yulistini, Yulistini Yuniar Lestari Yusri, Elfira Zakiya Ifana Putri