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All Journal Jurnal Ekonomi, Bisnis dan Kewirausahaan (JEBIK) International Journal of Education JURNAL ILMU MANAJEMEN DAN BISNIS LOKABASA REFLEKSI EDUKATIKA Jurnal Pendidikan Usia Dini Jurnal Terapan Ilmu Keolahragaan Jurnal Pendidikan Olah Raga Jurnal Manajemen STIE Muhammadiyah Palopo Kinestetik : Jurnal Ilmiah Pendidikan Jasmani JOURNAL SPORT AREA Al Qalam: Jurnal Ilmiah Keagamaan dan Kemasyarakatan AkMen JURNAL ILMIAH International Journal of Social Science and Business Walisongo Journal of Chemistry Jurnal SPORTIF : Jurnal Penelitian Pembelajaran JKPK (Jurnal Kimia dan Pendidikan Kimia) LAYAR: Jurnal Ilmiah Seni Media Rekam Riyadhoh : Jurnal Pendidikan Olahraga Loa : Jurnal Ketatabahasaan dan Kesusastraan Jurnal PORKES PINISI Discretion Review Community Empowerment Nobel Management Review Wacana : Jurnal Bahasa, Seni, dan Pengajaran DIMASATRA International Journal of Health, Engineering and Technology Physical Therapy Journal of Indonesia Delta-Phi Jurnal Pendidikan Matematika Maddana: Jurnal Pengabdian Kepada Masyarakat Jurnal Ikadbudi : Jurnal Ilmiah Bahasa, Sastra, dan Budaya Daerah JSSF : Journal of Sport Science and Fitness
Hernawan Hernawan
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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RETRACTED: Model Latihan Passing Bawah Bola Voli Pada Siswa Sekolah Menengah Pertama Abrasyi, Rendy; Hernawan, Hernawan; Sujiono, Bambang; Dupri, Dupri
Journal Sport Area Vol 3 No 2 (2018): December
Publisher : UIR Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25299/sportarea.2018.vol3(2).2135

Abstract

This article has been withdrawn at the request of the Chief Editor. The reason for the withdrawal is because this article was also published in the Prosiding Seminar dan Lokakarya Fakultas Ilmu Keolahragaan Universitas Negeri Jakarta. Link: (http://journal.unj.ac.id/unj/index.php/prosidingfik/article/view/10714). The condition for submitting a work for publication is that the author explicitly states that all of his works are original and have not appeared in publications elsewhere. We apologize to journal readers that this was not detected during the delivery process.
In Silico Analysis of Antibacterial Activity of Fatty Acids in Swietenia humilis Zucc. Seed Extract Against Staphylococcus aureus sortase A enzyme Asmara, Anjar Purba; Hernawan, Hernawan; Nuzlia, Cut
JKPK (Jurnal Kimia dan Pendidikan Kimia) Vol 9, No 2 (2024): JKPK (Jurnal Kimia dan Pendidikan Kimia)
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jkpk.v9i2.87473

Abstract

This study utilised molecular docking to predict the binding affinity of various fatty acids (FAs) found in Swietenia humilis to the sortase A (SrtA) protein target from Staphylococcus aureus. Binding energies, measured in kcal/mol, indicated the strength and stability of ligand-protein interactions, with lower values signifying stronger binding. The binding affinities of eight FAs as the active constituents in n-hexane extract of S. humilis and the positive control, gentamicin, were compared to assess their theoretical antibacterial activity. Palmitoleic acid exhibited the strongest binding affinity (-5.6 kcal/mol) among the FAs, suggesting the highest potential antibacterial activity, followed by linoleic, palmitic, linolenic, arachidic, tricosanoic, stearic, and oleic acids in decreasing order of affinity. Despite having weaker binding energies than gentamicin, a common gram-positive inhibitor from aminoglycoside derivative, FAs showed multiple hydrogen bonds and van der Waals interactions with key residues like ARG197, VAL168, VAL166, and ILE182, contributing to their binding stability. Palmitoleic acid formed multiple hydrogen bonds (ARG197 and GLY119) and significant van der Waals interactions, highlighting its strong theoretical binding. Stearic and oleic acids, although having higher binding energies, also formed critical hydrogen bonds, suggesting moderate potential activity. Gentamicin's single hydrogen bond suggests a highly specific binding site, which may result in high antibacterial activity despite fewer interaction points. The study indicated that FAs like palmitoleic and oleic acid show substantial potential as supplementary antibacterial agents, especially in the context of combating antibiotic resistance. This finding can pave a path for drug design and development to address the S. aureus's resistance.
Co-Authors Abd. Rasyid Syamsuri Abrasyi, Rendy Abrasyi, Rendy ADE SUTISNA, ADE Alamsyah, Zulfikar Anggara, Norma Anjar Purba Asmara Anshari, Dadang Anwar, Muhammad Saidun Apriana Sanga Dwi, Dicky Reva Asyrofi, Hasna Okta Baturante, Nur Jannah Cahyono, Tedi Choirudin, Choirudin Cipta, Indra Dadang Sunendar Dede Kosasih Defliyanto Deni Abdul Ghoni Devi Catur Winata Dingding Haerudin Dupri, Dupri Dupri, Dupri Erwin Erwin Fahmy Fachrezzy Fahrullah, Muh. Fandhi, Fandhi Haris Santosa Nugraha Hazrina Amni Hemalia, Alisha Hendrayana, Dian Hidayat, Neng Tanti Septiani Humaid, Hidayat Indra, Indra Aditiya Iswara, Delta James Klemen Lika James Tangkudung Jayawarsa, A.A. Ketut Karisdha Pradityana Khofia, Salma Nida Lukmana Sari, Ida Maghfiroh, Wasiattul Mariah Mariah Mariah, Mariah Mubyl, Mutiarini Muhammad Agus Muljanto Muhammad Syifa Amin Widigdo Mujaddid, Mujaddid Nugraha, Hartman Nur, Yuswari Nurhuda, Denny Adrian Nurkhalik Wahdanial Asbara Nurulfa, Rizky Nuzlia, Cut Pasaribu, Ahmad Muchlisin Natas Permana, Vira Vandini Pratiwi, Endang Putry, Keisya Aurelya Rachim, Erik Rahmah, Firda Aulia Rahman Rahman Rahmatilah, Lola Apriani Ramadhan, Muhammad Gilang Rayhan, Ilyassyah Retty Isnendes Rizal, Faisal Rombe, Yunita Pare RR. Ella Evrita Hestiandari RUHALIAH Dr., RUHALIAH Samsudin Samsudin Sandya, Cathleen Santosa, Haris Saribulan, Saribulan Septiadi, Angga Setiawan, Budi Rahayu Siti Mahmudha Slamet Sukriadi Solehudin, Oleh Sondari, Dea Sujarwo Sujarwo Sujiono, Bambang Sujiono, Bambang Sulaiman, Iman Syamsul Arifin Syihabuddin Syihabuddin Temmy Widyastuti Timur, Aprilia Intan Tri Indri Hardini Usep Kuswari Utama, Made Bang Redy Vidya Hartono, Fajar Wa’asil, Fatirul Wattimena, Ferry Yohannes Wenly, Ayu Purnama WIDIASTUTI - Yayat Sudaryat Yulianeta