Claim Missing Document
Check
Articles

Aerobic exercise improves spatial memory in a rat model of meningitis Zaidah, Lailatuz; Soetrisno, Soetrisno; Purwanto, Bambang; Kristiyanto, Agus; Wasita, Brian; Widyaningsih, Vitri
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.977

Abstract

Infections of the nervous system, such as acute bacterial meningitis, pose serious health problems that require immediate intervention. In experimental animals, exposure to lipopolysaccharide (LPS) is used to induce meningitis. Aside from drug intervention to reduce inflammation in meningitis, aerobic exercise helps to maintain the regulatory mechanisms of brain homeostasis through anti-inflammatory mechanisms. The aim of this study was to evaluate the effect of aerobic exercise on malondialdehyde (MDA), nuclear factor-kappa B (NF-κB), insulin-like growth factor 1 (IGF-1), endothelial nitric oxide synthase (eNOS), brain-derived neurotrophic factor (BDNF), apoptosis, and spatial memory. A four-week experimental study was conducted using 18 rats, which were randomly divided into three different groups (six rats per group): healthy rats as negative controls (non-meningitis), a treatment group treated with antibiotic treatment (meningitis group), and a third group (aerobic exercise group) treated with antibiotics and aerobic exercise following LPS-induced meningitis. Data were analyzed using a one-way analysis of variance (ANOVA) test, and the comparison between groups used the Bonferroni post-hoc test. The results showed that aerobic exercise significantly reduced MDA (p<0.001), NF-κB (p=0.035), and apoptosis (p=0.020) while increasing the serum levels of IGF-1 (p<0.001), eNOS (p=0.011), and BDNF (p=0.001) levels. Improvement in spatial memory was significant in the aerobic exercise group (p<0.001). This study suggested that aerobic exercise could be a promising adjunct therapy in meningitis management strategies, particularly due to its effect on improving spatial memory. Further clinical trials are needed to confirm these findings for clinical use.
Optimism and causal analysis in adventure motorcycling: An investigation of athletes’ resilience Wulandari, Cahyani; Kristiyanto, Agus; Syaifullah, Rony
Journal Sport Area Vol 8 No 2 (2023): August
Publisher : UIR Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25299/sportarea.2023.vol8(2).12493

Abstract

Resilience in motorcycle adventure activities in each individual requires resilience to face challenges. However, this motorcycle activity has many failures and problems that usually bring up emotions. The purpose of this research was to examine the resilience of community members participating in motor adventure activities. Mixed-methods research was used, with a sequential explanatory research basic design. This study began with quantitative methods and proceeded to qualitative methods. A questionnaire was used to collect quantitative data, while an interview was used to acquire qualitative data. The accumulated interpretation of scores obtained on emotion regulation was 75% (high), impulse control 82% (very high), optimism 84% (very high), causal analysis 82% (very high), empathy 71% (high), self-efficacy 78% (high), and reaching out 87% (very high). This research is limited to the sample used and the scope of research is limited to one area or community. Future research can broaden the scope of research by exploring the factors that influence the resilience of different motorcycle adventure actors, such as psychological, social, and environmental factors. In addition, research can be focused on efforts to increase the resilience of motorcycle adventure actors, such as through training or education programs. The results of this study provide consideration, support, and contribution of ideas to stakeholders to increase the resilience of adventure motorcycle actors in facing challenges in their activities.
Effectiveness of a modified TGfU program in enhancing volleyball skills among elementary school students Ariwibowo, Yuyun; Sugiyanto, Sugiyanto; Kristiyanto, Agus; Riyadi, Slamet
Jurnal Cakrawala Pendidikan Vol. 43 No. 2 (2024): Cakrawala Pendidikan (June 2024)
Publisher : LPMPP Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/cp.v43i2.66632

Abstract

This research is aimed at determining the effectiveness of the modified TGfU volleyball learning model in enhancing the technical skills of male senior students at elementary schools. The research method used to test effectiveness was an experimental research method by comparing the modified TGfU volleyball learning model with traditional physical education classes typically taught by teachers at school. This research was conducted at Kepuh Elementary School with the subjects of 20 male senior students as the experimental group and Patalan Baru Elementary School using the same 20 male senior students as the control group. The instruments used were the American Alliance for Health, Physical Education, and Recreation (AAHPER) Serving Accuracy Test and the Brumbach forearm pass wall-volley test. The application of the modified TGfU volleyball learning model shows the differences in results between the experimental group and the control. The results of the research show that here were differences between the experimental and control groups in the forearm serve (p < 0.001), overhead serve (p < 0.001), and forearm passing skills (p = 0.004), with a p-value of less than 0.05 indicating that the difference is statistically significant. The findings demonstrate that the modified TGfU volleyball learning model outperforms the traditional PE teaching method in enhancing the forearm serve, overhead serve, and forearm passing skills.
THE RELATIONSHIP BETWEEN MICRONUTRIENT INTAKE AND HAEMOGLOBIN LEVELS IN MALE ADOLESCENT FOOTBALL ATHLETES Kristiana, Irma; Kristiyanto, Agus; Muthmainah, Muthmainah
Media Penelitian dan Pengembangan Kesehatan Vol. 33 No. 3 (2023): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v33i3.1754

Abstract

Atlet sepak bola dituntut memiliki stamina yang baik saat latihan maupun bertanding untuk mencapai prestasi yang baik. Kadar haemoglobin yang baik dapat membuat atlet tidak mudah mengalami kelelahan, sehingga kadar hemoglobin merupakan aspek yang perlu diperhatikan oleh atlet sepak bola. Selain itu, asupan zat besi dan vitamin C seorang atlet juga perlu diperhatikan. Hal ini dikarenakan, asupan zat besi dan vitamin C merupakan komponen yang sangat berpengaruh terhadap pembentukan kadar hemoglobin. Penelitian ini bertujuan untuk menganalisis hubungan antara asupan zat besi dan vitamin C dengan kadar hemoglobin pada atlet sepak bola remaja putra. Desain penelitian yang digunakan pada penelitian ini adalah cross-sectional. Jumlah sampel pada penelitian ini yaitu sebanyak 65 atlet sepak bola di tempat pelatihan Pendidikan Sepak Bola Bonansa UNS Solo. Penelitian ini dilakukan pada bulan Oktober-November 2021 di Surakarta. Data asupan zat besi dan vitamin C diukur menggunakan Semi-Quantitative Food Frequency Questionnaire (SQFFQ). Data kadar haemoglobin diukur dengan metode spektrofotometer. Data dianalisis dengan menggunakan uji Spearman Rank dan Product Moment Pearson. Hasil penelitian ini menunjukkan bahwa asupan zat besi (r = 0,699 dan p < 0,001) dan vitamin C (r = 0,643 dan p < 0,001) terdapat hubungan positif dengan kadar haemoglobin. Asupan zat besi dan vitamin C memiliki hubungan yang signifikan dengan kadar haemoglobin. Pada penelitian selanjutnya disarankan untuk menentukan faktor apa saja yang dapat mempengaruhi kadar haemoglobin atlet remaja laki-laki.
Edukasi Pengetahuan Gizi Olahraga bagi Atlet Siswa SSB Pandawa Footbal Academy Sukoharjo Ellyas, Intan Suraya; Kristiyanto, Agus; Mariyanto, Muhammad; Lelono, Sarjoko; Riyadi, Slamet; Utomo, Tri Aprilijanto; Daryanto, Daryanto; Wulansari, Dasih Ayu
Jurnal Pengabdian Olahraga Masyarakat Vol 5, No 2 (2024): November 2024
Publisher : Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/jpom.v5i2.20464

Abstract

The Pandawa Football Academy (PFA) in Sukoharjo is one of the top football schools (SSB) in the Sukoharjo and Solo Raya regions. The academy has achieved various accomplishments at the district, provincial, and national levels. However, based on observations and interviews, it was found that during the training and learning process, comprehensive nutrition knowledge had not been provided to the student athletes. Knowledge about nutritious food ingredients, meal selection, and meal planning during training and competition periods was only obtained from classroom material, which was not in-depth. There has not been any specific training for student athletes on the benefits of sports nutrition knowledge that can support performance during competitions. Therefore, this community service activity aims to increase the sports nutrition knowledge of student athletes using a service-learning method, which includes an educational stage for the student athletes. The results of this training showed an increase in the sports nutrition knowledge of the student athletes at PFA Sukoharjo (p-value 0.0000.01). There was an increase in the level of sports nutrition knowledge from an average category of moderate to high, using the NUKYA questionnaire in the Indonesian language version. The participants in this training were categorized as adolescent athletes. The nutrition knowledge gained can serve as a foundation for these student athletes as they become professional players.
Effect of clove flower extract (Syzygium aromaticum) administration timing on skeletal muscle damage induced by eccentric exercise: An in vivo study Ningrum, Tyas Sari Ratna; Doewes, Muchsin; Indarto, Dono; Cilmiaty, Risya; Kristiyanto, Agus; Widyaningsih, Vitri
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1680

Abstract

Eccentric exercise often leads to oxidative stress, inflammation, and muscle damage that impair athletic performance. To counter these adverse effects, clove flower extract (Syzygium aromaticum) offers promising potential as a natural remedy to promote muscle repair with its potent antioxidant and anti-inflammatory properties. The aim of this study was to assess the effects of clove flower extract administration timing on oxidative stress and inflammatory responses in skeletal muscle damage induced by acute eccentric exercise in mice. This study used a post-test-only control group design, involving 35 male mice (Mus musculus, Balb/c) randomly divided into five groups: a healthy control group (HC) with no exercise and no treatment, a negative control group (NC) with exercise but no treatment, and three treatment groups: T1, T2, and T3 (clove flower extract 24 hours before exercise, immediately after exercise, and 24 hours after exercise, respectively). The treatment groups received a single dose of clove flower extract (500 mg/kg body weight). The skeletal muscle damage of mice was collected for the NADPH oxidase (NOX) and superoxide dismutase (SOD) activities using spectrophotometry, and toll-like receptor 4 (TLR4) and interleukin-8 (IL-8) measurements using enzyme-linked immunosorbent assay (ELISA). Moreover, the skeletal muscle damage was analyzed through the histopathological method. Data were analyzed using one-way analysis of variance (ANOVA) followed by Fisher's least significant difference (LSD) tests as a post hoc test. The result showed that clove flower extract significantly reduced NOX activity (p=0.049) and IL-8 levels (p=0.032), and increased SOD activity (p=0.001) while not significantly affecting the TLR4 levels (p=0.532). Moreover, the results showed a significant reduction in muscle damage (p=0.001). The study highlights that the administration of clove flower extract (500mg/kg bw) can be given 24 hours before, immediately after exercise, or 24 hours after exercise to prevent muscle damage.
Meta-Analysis Effectiveness of Massage on Spasticity in Children with Cerebral Palsy Muazarroh, Salma; Kristiyanto, Agus; Prasetya, Hanung
Indonesian Journal of Medicine Vol. 7 No. 2 (2022)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (30.537 KB) | DOI: 10.26911/theijmed.2022.7.2.540

Abstract

Background: Children with spastic cerebral palsy generally experience spasticity in the upper and lower extremities. Spasticity is stiffness that occurs due to damage to the central nervous system caused during the child's growth and development from prenatal to postnatal. Spasticity can be controlled with intervention. The purpose of this study is to analyze, and estimate the effectiveness of massage for spasticity in children with cerebral palsy.Subjects and Method: This study uses a meta-analysis study design with PICO as follows: P= children with cerebral palsy, I= massage, C= non massage, O= Modified Ashworth Scale (MAS). The article search process was carried out between 2000-2020 using databases from PubMed, Google Scholar, PEDro, NCBI. Based on the database, there were 9 articles that met the inclusion criteria. This study involved 817 articles. The analysis was performed using Review Manager software (RevMan 5.3).Results A total of 9 Randomized Control Trial (RCT) studies from Europe, America, Asia and Africa were selected for systematic review and meta-analysis. COVID-19 patients receiving Ivermectin therapy decreased the duration of hospital stay by 1.52 units compared to standard therapy and this result was statistically significant (SMD= -1.52; 95% CI= -2.34 to -0.70; p= 0.003).Conclusion: Ivermectin can reduce the duration of hospital stay for COVID-19 patients.Keywords: Massage, cerebral palsy, Modified Ashworth Scale, meta analisisCorrespondence: Salma Muazarroh. Masters Program in Public Health. Universitas Sebelas Maret, Jl.Ir. Sutami 36A, Surakarta 57126, Jawa Tengah, Indonesia. Email: salma.azza@gmail.com. Mobile: 085642431178.Indonesian Journal of Medicine (2022), 07(02): 209-218https://doi.org/10.26911/theijmed.2022.07.02.09
Persepsi Kelompok Penerima Manfaat terhadap Program Pekarangan Pangan Lestari (P2L) di Kota Surakarta Anantanyu, Sapja; Arif, Akbarudin; Kristiyanto, Agus; Saptaningtyas, Haryani; Suminah; Retnaningtyas, Triya Ayu
Jurnal Penyuluhan Vol. 21 No. 01 (2025): Jurnal Penyuluhan
Publisher : Department of Communication and Community Development Sciences and PAPPI (Perhimpunan Ahli Penyuluhan Pembangunan Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25015/21202551299

Abstract

Kebijakan pertanian perkotaan menjadi strategi pemerintah dalam mendukung ketahanan pangan masyarakat kota. Program Pekarangan Pangan Lestari (P2L) dari Kementerian Pertanian bertujuan meningkatkan perekonomian dan kesejahteraan masyarakat kota melalui pemanfaatan lahan tidak produktif sebagai sumber pangan. Penelitian ini mengeksplorasi kebijakan dan implementasi P2L di Kota Surakarta, menganalisis persepsi kelompok penerima manfaat, serta faktor-faktor yang memengaruhinya. Penelitian ini menggunakanmixed method, menggabungkan studi kasus dengan wawancara mendalam terhadap 21 informan dan survei terhadap 125 responden dari 20 kelompok penerima manfaat. Hasil penelitian menunjukkan implementasi P2L umumnya sesuai petunjuk teknis, namun beberapa kelompok tidak lagi aktif karena program telah selesai. Partisipasi anggota kelompok masih rendah, sehingga pelaksanaan program kurang optimal. Berdasarkan hasil analisis, persepsi anggota kelompok penerima manfaat program terhadap aspek manfaat yaitu tidak baik (49,6%), serta terhadap aspek pelaksanaan dan keberlanjutan yaitu ragu-ragu (masing-masing 48,8% dan 54,4%). Uji regresi menunjukkan tingkat pendidikan dan dukungan lingkungan sosial ekonomi berpengaruh signifikan terhadap persepsi, sedangkan kekosmopolitan tidak berpengaruh. Kedepan, agar program optimal dan berkelanjutan, perlu dilakukan peningkatan partisipasi aktif melalui pembagian tugas yang jelas, penyusunan sistem insentif, dan pengenalan model pengelolaan berbasis komunitas; meningkatkan pemahaman dan kesadaran melalui pelatihan rutin dan penyuluhan tentang dampak positif program jangka panjang; serta pengembangan pasar lokal dan branding produk.
Menjelajahi perkembangan pariwisata olahraga paralayang: Studi kasus perbandingan di Bali dan Jawa Tengah Indriyani, Nur Afifah; Kristiyanto, Agus; Riyadi, Slamet
Jurnal SPORTIF : Jurnal Penelitian Pembelajaran Vol 11 No 1 (2025): Jurnal SPORTIF: Jurnal Penelitian Pembelajaran
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/js_unpgri.v11i1.25034

Abstract

One of Indonesia's top priorities still is tourism, which helps to boost regional development, employment, and the national economy. Among its developing sub-sectors, sport tourism, especially paragliding, has become increasingly popular because of Indonesia's varied and breathtaking natural surroundings. Still, differences in the evolution of tourism locations make it difficult to reach fair and sustainable tourism expansion. This paper attempts to investigate the main elements affecting the growth of paragliding sport tourism by means of a comparative case study of RIUG Paragliding in Bali and the Kemuning Paragliding Community in Central Java. Using a qualitative descriptive-comparative approach, the study thoroughly investigates tourism development strategies from several regional settings. Six key informants, three from each site who directly oversee tourist management, were used in a purposeful sampling process to gather data. Under the direction of the 4A tourism framework (Attractions, Accessibility, Amenities, and Ancillary Services), the study used in-depth interviews, structured observations, and document analysis. Data were transcribed, coded, categorized, and triangulated to guarantee validity and dependability. The results expose several methods of development: Whereas the Kemuning Paragliding Community stresses local resource use and volunteer involvement, RIUG Paragliding Bali uses a corporate-based model with contemporary facilities, integrated promotion methods, and stakeholder collaboration. The study comes to the conclusion that efficient development of paragliding sports tourism calls for cooperative governance involving corporate businesses, local communities, and government institutions to support sustainable and inclusive tourism expansion. 
Effects of aerobic exercise and high-intensity interval training on muscle damage in an overtraining rat model Syetiawinanda, Amriansyah; Doewes, Muchsin; Purwanto, Bambang; Soetrisno, Soetrisno; Kristiyanto, Agus; Pamungkasari, Eti Poncorini
Physical Therapy Journal of Indonesia Vol. 6 No. 1 (2025): January-June 2025
Publisher : Universitas Udayana dan Diaspora Taipei Medical University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/ptji.v6i1.297

Abstract

Background: Overtraining is commonly associated with elevated oxidative stress, inflammatory responses, and structural damage to muscle fibers, all of which contribute to a decline in physical performance. This study aimed to assess the impact of aerobic exercise on biomarkers including malondialdehyde (MDA), interleukin-6 (IL-6), caspase-3, nitric oxide (NO), superoxide dismutase (SOD), as well as the integrity of the sarcolemma. Methods: A six-week experimental study was conducted using 24 rats, which were randomly divided into three groups (n = 8 per group): a negative control group (no treatment), an aerobic exercise group, and a high-intensity interval training (HIIT) group. The levels of biochemical markers, including malondialdehyde (MDA), interleukin-6 (IL-6), nitric oxide (NO), and superoxide dismutase (SOD), were measured using the enzyme-linked immunosorbent assay (ELISA) technique. Additionally, the expression of caspase-3 was determined through immunohistochemical (IHC) analysis. Muscle tissue damage was evaluated by means of histopathological examination. The data were analyzed using a one-way analysis of variance (ANOVA), followed by the Mann-Whitney post hoc test to assess differences between groups. Results: The findings indicated that aerobic exercise did not result in a statistically significant reduction in malondialdehyde (MDA) (p = 0.833), interleukin-6 (IL-6) (p = 0.800), nitric oxide (NO) (p = 0.791), or superoxide dismutase (SOD) (p = 0.520) levels. Nevertheless, the aerobic exercise group exhibited a significantly lower expression of caspase-3 compared to the other groups (p = 0.023). Furthermore, aerobic exercise was associated with a significant reduction in muscle tissue damage (p = 0.001). Conclusion: The findings of this study indicate that both aerobic exercise and high-intensity interval training (HIIT) have the potential to be utilized as therapeutic approaches for mitigating exercise-induced muscle damage, primarily through their positive influence on sarcolemma stability. However, additional clinical investigations are necessary to confirm these results and establish their relevance for clinical implementation.
Co-Authors Agus Margono Alfira fitriana Anggriani, Atika Febri Aprilia, Khalida Nawa Apriliyani, Florida Betty Arif, Akbarudin Ayuningtiyas, Citra Bambang Purwanto Berek, Maria Imakulata Bhisma Murti Brian Wasita Cahyo Seftyono Danang Pujo Broto Daniyar, Pamogsa Ratri Adha Daryanto Daryanto Dono Indarto Edy Legowo, Edy Ellyas, Intan Suraya Eti Poncorini Pamungkasari Faidillah Kurniawan Fiola Indah Putri Pratama Firmanurulita, Fadhila Forestry, Silmi Gontara, Satria Yudi Gunawati, Arista Hangga Kusuma, Hangga Hari Hanggoro, Hari Herry Widyastono, Herry Ian Alfian Riyanto, Ian Alfian Indriyani, Nur Afifah Istiqomah, Isnanda Putri Nur Joko Nurkamto Juego, Bonn Kardiyanto, Deddy Whinata Khoirul Huda Kiyatno Kiyatno Kristiana, Irma Lelono, Sarjoko M.Pd S.T. S.Pd. I Gde Wawan Sudatha . Mariyanto, Muhammad Maryanto, Muhammad Muazarroh, Salma Muchsin Doewes Muh. Furqon Hidayatullah Muhammad Hisyam Muthmainah Muthmainah Nenot'ek, Frislin Paskaliner Yonatan NINGRUM, TYAS SARI RATNA Noer Rachma Nugroho, Kristanto Adi Prasetya, Hanung Pratama, Andika Priya Rachman, M Erika Rahardjo, Setyo Sri Rahelli, Yeti Rahman, Ihda Diyaur Restian Gigih sejati, Restian Gigih Retnaningtyas, Triya Ayu Risya Cilmiaty, Risya Rokhayah, Fajar Rokhayah, Fajar Rony Syaifullah, Rony Sadullah, Akhmad Safitri, Lina Eta Sapja Anantanyu, Sapja Sapta Kunta Purnama Saptaningtyas, Haryani Sholikah, Mutiana Agustin Sima Asmara Dewa Marya Mahardika Putri Siswahyudianto Slamet Riyadi Soetrisno Soetrisno Sugiyanto - Sumaryanto Sumaryanto, Sumaryanto Suminah Sunardi Sunardi Suprayogi, Dody Susilo, Fahmi Eko Syetiawinanda, Amriansyah Tonang Dwi Ardyanto Triasmono, Haris Kukuh Utomo, Tri Aprilijanto Vania Martha Yunita Vitri Widyaningsih Widayat, Tulus Windiartha, Abdy Windiartha, Abdy Wulandari, Cahyani Wulansari, Dasih Ayu Yoga Yuniadi Yudanto Yudanto Yuyun Ari Wibowo Zaidah, Lailatuz Zalaff, Katsran Zulkarnain, Alfian Noha