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Hubungan Healthy Eating Index Dengan Kenaikan Berat Badan Ibu Selama Kehamilan Di Sumatera Barat Helfina, Riska; Lipoeto, Nur Indrawaty; Purnakarya, Idral
Majalah Kedokteran Andalas Vol. 48 No. 2 (2025): MKA April 2025
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v48.i2.p138-147.2025

Abstract

AbstractObjective: To determine the association between the healthy eating index of pregnant women and maternal weight gain during pregnancy in West Sumatra.Methods: Research with a cross-sectional design in West Sumatra on 110 pregnant women.This research is an analysis of secondary data from the study "Giving Dadiah on pregnancy and birth outcomes in West Sumatra".The study used data from 24-hour recall of pregnant women in the first trimester, second trimester and third trimester and pregnant women's weight data.Results: The study showed that there was a relationship between the HEI of pregnant women and the increase in maternal weight during pregnancy with p = 0.049 with a value of r = 0.188.Conclusion: There is a relationship between the healthy eating index of pregnant women and the increase in maternal weight during pregnancy.Keywords:  healthy eating index; weight gain; pregnant woman
Effect of Biscuits Enriched with Bilih Fish (Mystacoleucus padangensis) on Growth of Experimental Rats Diana, Fivi Melva; Rimbawan, Rimbawan; Damayanthi, Evy; Dewi, Mira; Juniantito, Vetnizah; Lipoeto, Nur Indrawaty
Jurnal Gizi dan Pangan Vol. 15 No. 1 (2020)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (311.198 KB) | DOI: 10.25182/jgp.2020.15.1.11-18

Abstract

The research aimed to produce biscuits formulated with Bilih fish and to analyse the effect of Bilih-fish-based biscuits on the growth of experimental rats. Six biscuit formulas were developed using three different amounts of Bilih fish flour (0 g, 20 g, and 30 g added to one formula dough) and two flavors (chocolate and vanilla). One biscuit formula was selected based on the best organoleptic test. Four treatments were applied to 24 male growing rats (21 day olds of the Spraque Dawley strain) for 28 days using a completely randomized design study. The treatments used were P1 (standard feed), P2 (standard feed + standard biscuits), P3 (standard feed + standard biscuits + pure omega-3 oil) and P4 (standard feed + the best formula biscuit). The parameters measured on rats were weight and tail length. The best formula biscuit based on the organoleptic test was the chocolate-flavor biscuits prepared with 20 g Bilih fish flour. The longest tail length was found in the P4 treatment (2,257±0.52 cm), which was significantly longer than the P2 (1.46±0.34 cm) and P1 (1.34±0.29 cm) treatments. No significant weight differences were found among the rats in all treatments. Hence, the chocolate-flavor biscuits formulated with the addition of 20 g Bilih fish flour increased the linear growth in experimental rats as shown by the significant difference in the tail lengths found in the treatment group.
Unraveling the Link between Obesity and Tuberculosis: A Systematic Review of the Underlying Mechanisms Deddy Herman; Rizanda Machmud; Nur Indrawaty Lipoeto
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 2 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i2.1205

Abstract

Background: Tuberculosis (TB) and obesity are significant global health concerns with potentially complex interactions. Obesity, through its effects on metabolism, inflammation, and the immune system, may influence TB susceptibility, progression, and treatment outcomes. This systematic review aims to analyze the published literature on the relationship between obesity and TB, focusing on the underlying mechanisms. Methods: A systematic search of PubMed, Science Direct, and Google Scholar was conducted for articles published in the last 10 years. The search strategy included keywords such as "tuberculosis," "TB," "obesity," and "BMI." Articles were selected using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) method. Results: The review identified 11 studies that met the inclusion criteria. The studies revealed a complex relationship between obesity and TB, with nutritional status, immunity, and diabetes mellitus (DM) playing key roles. Obesity can alter the immune response to TB, potentially increasing the risk of disease and affecting treatment efficacy. Conclusion: The relationship between obesity and TB is multifaceted, with obesity potentially influencing both disease susceptibility and outcomes. Further research is needed to fully elucidate the underlying mechanisms and to develop targeted interventions for individuals with both obesity and TB.
Iron Deficiency and Anemia of Inflammation in Tuberculosis: A Systematic Review of the Evidence Deddy Herman; Rizanda Machmud; Nur Indrawaty Lipoeto
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 2 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i2.1207

Abstract

Background: Tuberculosis (TB) remains a major global health problem, with anemia being a frequent comorbidity. Anemia in TB is multifaceted, with iron deficiency and anemia of inflammation (AI) being the most common types. This systematic review aims to synthesize the evidence on iron deficiency and AI in TB, their prevalence, impact on outcomes, and management strategies. Methods: A systematic search of PubMed and ScienceDirect databases was conducted for articles published in the last 10 years. Observational studies examining the prevalence, types, and impact of anemia on TB outcomes were included. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. Results: The review included 7 studies involving 1,133 participants. Anemia prevalence ranged from 61% to 89% in TB patients. AI was the predominant type, with iron deficiency also prevalent. Anemia was associated with increased mortality, delayed sputum culture conversion, and impaired TB treatment response. Conclusion: Anemia, primarily AI and iron deficiency, is highly prevalent in TB and negatively impacts treatment outcomes and survival. Effective management of anemia is crucial for improving TB outcomes. Further research is needed to optimize diagnostic and treatment strategies for iron deficiency and AI in TB.
Pengaruh Pemberian Kukis Kombinasi Tepung Ikan Tongkol (Euthynnus affinis) dan Tepung Bayam (Amaranthus tricolor) Dengan Penambahan Probiotik Dadih Terhadap Kadar Feritin Serum Pada Tikus Wistar Anemia Azahra, Azizah Firda; Lipoeto, Nur Indrawaty; Rofinda, Zelly Dia; Rita, Rauza Sukma; Desmawati, Desmawati; Yulia, Dwi; Fasrini, Ulya Uti
SENTRI: Jurnal Riset Ilmiah Vol. 4 No. 11 (2025): SENTRI : Jurnal Riset Ilmiah, November 2025
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/sentri.v4i11.4950

Abstract

Anemia is a global health problem characterized by low hemoglobin and ferritin levels due to iron deficiency, which affects growth, cognition, and disease risk, particularly in children and women of reproductive age. Local food–based nutritional interventions such as skipjack tuna (heme iron), spinach (non-heme iron), and dadih (probiotics) have the potential to provide synergistic effects in improving iron status. This study aimed to determine the effect of cookies made from a combination of skipjack tuna flour and spinach with the addition of dadih probiotics on serum ferritin levels, as well as the effectiveness of Sodium Nitrite (NaNO₂) in decreasing ferritin and hemoglobin levels as indicators of anemia. The study used a Post-Test Only Control Group design with 36 female Wistar rats induced with anemia using NaNO₂ at a dose of 25 mg/200 g BW for 18 days, then divided into six treatment groups for 28 days. Ferritin levels were measured using the ELISA method. The results showed that administering cookies made from the combination of skipjack tuna flour and spinach with dadih probiotics significantly increased ferritin levels (P=0.000) compared to the control and single-ingredient groups. NaNO₂ was proven effective as an anemia-inducing agent. This combined cookie formulation has the potential to improve serum ferritin levels.
EFEKTIFITAS PEMBERIAN SUSU KAMBING FERMENTASI TERHADAP ANTROPOMETRI BAYI BARU LAHIR Ira Suryanis; Hasmiwati, Hasmiwati; Nur Indrawaty Lipoeto; Novirman Jamarun
Nusantara Hasana Journal Vol. 5 No. 7 (2025): Nusantara Hasana Journal, December 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i7.1834

Abstract

The balance of the gut microbiota during pregnancy is essential for maintaining maternal health and supporting optimal fetal development. Fermented goat’s milk contains naturally occurring probiotics that contribute to microbiota homeostasis and improved maternal nutritional status. This study aimed to evaluate the effect of fermented goat’s milk consumption on newborn anthropometric outcomes. Two group pretest posttest control was applied involving 15 third-trimester pregnant women who met the inclusion criteria. Participants consumed 75 mL of fermented goat’s milk daily for a period of 9–12 weeks. Maternal characteristics and neonatal anthropometric parameters were collected through structured observations and questionnaires. Data were analyzed using paired statistical tests. The findings demonstrated statistically significant improvements (p < 0.05) in neonatal birth weight, body length, and head circumference following the intervention. These results indicate that fermented goat’s milk may positively influence fetal growth without inducing gut microbiota dysbiosis. Further studies employing controlled designs and larger sample sizes are warranted to confirm these findings and elucidate the underlying mechanisms.
Maternal and Environmental Determinants of Linear and Cranial Growth: A 6-Year Longitudinal Study in West Sumatra Fasrini, Ulya Uti; Syah, Nur Afrainin; Serudji, Joserizal; Lipoeto, Nur Indrawaty
Journal of Health and Nutrition Research Vol. 5 No. 1 (2026)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v5i1.1355

Abstract

This study aimed to identify the integrated maternal, environmental, and biological predictors of child linear growth (Height-for-Age Z-score; HAZ) and cranial growth (Head Circumference; HC) at age six in a longitudinal Indonesian cohort. A prospective cohort study followed 120 mother-child pairs in West Sumatra from the first trimester of pregnancy (2017) through age six (2023). Data were collected on maternal nutrient intake (SQ-FFQ), Vitamin D status (serum 25(OH)D), physical activity, and environmental conditions. Integrated multiple linear regression models were constructed to determine independent predictors, adjusted for maternal education and prepregnancy BMI. In the final integrated models, child HAZ at age six was significantly predicted by maternal first-trimester energy intake (β = 0.0006, p = 0.006), maternal height (p = 0.012), and child energy intake (p = 0.005). Cranial growth (HC) was primarily predicted by birth weight (β=0.0011, p=0.004) and maternal physical activity index (p=0.031). Maternal Vitamin D sufficiency (≥30 ng/mL) in the first trimester showed higher mean HAZ and HC compared to deficient levels (<20 ng/mL), although these differences were not statistically significant. The findings indicate that early pregnancy may be an important period for establishing growth trajectories, shaped by maternal nutritional status and environmental conditions. These observations support the potential value of strengthening pre-conception and early pregnancy care, including nutritional optimization and access to safe water; however, further studies are required to confirm these patterns and inform targeted interventions in West Sumatra.
Co-Authors Adang Bachtiar Adrial Adrial, Adrial Afdal Afdal, Afdal Ahmad Kurniawan Akbar Akbar Shiddiq Akbar, Fathurrahman Ramadhana Amilia, Fenni Amirah Zatil Izzah Andani Eka Putra Anggi Setiawan Annisaul Husna Anugerahwati, Ammara Asya Ariadi, Ariadi Ariani, Peny Arif Sabta Aji Arni Amir Asta, Sri Wulanda Ayunda, Aldina Azahra, Azizah Firda Badriul Hegar Bobby Indra Utama Chandra, Dian Novita Dasman, Hardisman Defrin, Defrin Delmi Sulastri Delmi Sulastri Desmawati Desmawati Effatul Afifah. Ester Pakpahan Eva Chundrayeti Eva Chundrayetti Evy Damayanthi Fathiyyatul Khaira Feby Andammori Finny Fitry Yani Firdawati Fivi Melva Diana, Fivi Melva Hardisman Hardisman Dasman Harun Harnavi Hasmiwati Haviz Yuad Helfina, Riska Helmizar Hema Malini, Hema Herman, Deddy Husna Yetti Idral Purnakarya Ilmiawati Ilmiawati, Ilmiawati Indrapriyatna, Ahmad Syafruddin Intan, Shinta Ayu Ira Suryanis Lestari, Prasetya Lubis, Basyariah Malinda Meinapuri Masrul Mayetti Mayetti Mila Agustia Mudjiran Muhammad Rayyan Rifqi Mulyono, Andriani Neherta, Meri Nelmi Silvia Nidya Ikha Putri Novirman Jamarun Nur Afrainin Syah Putri, Viorika Marsafa Rahmani Welan Rahmi Nurjannah Rapida Saragih Rauza Sukma Rita Restu Susanti Reza, Mohamad Rimbawan , Rinaldiansyah Rinaldiansyah Rinang Mariko, Rinang Rizanda Machmud Rizanda Machmud Rosfita Rasyid Roza Mulyana Rozi Sastra Purna Saputri, Winda Dwi Sari, Nur Mala Setiawati, Sandy Susmiati Susmiati Syahrul, Muhammad Zulfadli Taufiqa, Zuhrah Ulfa Farrah Lisa, Ulfa Farrah Ulya Uti Fasrini Utama, Bobby Indra Vaulinne Basyir Vetnizah Juniantito Willya Eka Putri Winda Irwanti, Winda Yulia, Dwi Yulizawati, Yulizawati Yuniar Lestari YURNILA Yusrawati Yusrawati yusuf, rahmi novita Zelly Dia Rofinda Zifrianthi Minanda Putri