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All Journal As-syifaa Jurnal Farmasi ALCHEMY Jurnal Penelitian Kimia Jurnal SainHealth Food Science and Technology Journal (Foodscitech) JPBIO (Jurnal Pendidikan Biologi) Community Development Journal Amalee: Indonesian Journal of Community Research & Engagement INTEGRITAS : Jurnal Pengabdian Bubungan Tinggi: Jurnal Pengabdian Masyarakat Community Development Journal: Jurnal Pengabdian Masyarakat Among : Jurnal Pengabdian Masyarakat Mechonversio: Mechanical Engineering Journal Mattawang: Jurnal Pengabdian Masyarakat DedikasiMU: Journal of Community Service Jurnal Abmas Negeri (JAGRI) Jurnal Pengabdian kepada Masyarakat Bina Darma CHEDS: Journal of Chemistry, Education, and Science Indonesian Journal of Chemistry and Environment PELS (Procedia of Engineering and Life Science) Prosiding Seminar Nasional Pengabdian Kepada Masyarakat Open Community Service Journal Prosiding Seminar Nasional Universitas Ma Chung Prosiding Seminar Nasional Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Bangsa Journal of Education Technology and Civic Literacy (JET CIVIL) Jurnal Akselerasi Merdeka Belajar dalam Pengabdian Orientasi Masyarakat (Jurnal AMPOEN) Journal of Mandalika Social Science Jurnal Pengabdian Sosial E-Amal: Jurnal Pengabdian Kepada Masyarakat International Journal of Mathematics and Science Education Jurnal Ragam Pengabdian BISMA: Bimbingan Swadaya Masyarakat
Lilla Puji Lestari
Universitas Maarif Hasyim Latif
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Advances in diabetes intervention: Targeting hormonal regulation, hIAPP, glucose transport, and key enzymatic pathways Sari, Mulia Safrida; Lestari, Lilla Puji; Imun, Meri M.; Sriyanti, Cut; Ramli, Nurlaili
JPBIO (Jurnal Pendidikan Biologi) Vol 10, No 2 (2025): November 2025
Publisher : STKIP Persada Khatulistiwa Sintang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31932/jpbio.v10i2.4850

Abstract

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia resulting from impaired insulin secretion or action. This condition remains a leading cause of global morbidity and mortality and is closely associated with various metabolic complications and cancer risk. This study aimed to identify potential molecular targets and hormonal regulatory mechanisms involved in diabetes management. A systematic review was conducted by searching indexed scientific articles in databases such as ScienceDirect and Google Scholar using the keywords “diabetes,” “molecular targets,” “insulin sensitivity,” and “hormonal regulation.” The analysis identified six major molecular mechanisms contributing to improved insulin action and glucose homeostasis, involving targets such as human islet amyloid polypeptide (hIAPP), ?-glucosidase, dipeptidyl peptidase-4 (DPP-4), sodium-glucose co-transporter-2 (SGLT2), glucose transporter type 4 (GLUT4) translocation, RNA-binding proteins (RBPs), and key enzymatic pathways associated with glucose metabolism. The development of therapeutic approaches directed toward these pathways could significantly enhance diabetes control, improve insulin sensitivity, and prevent long-term complications.
Development of an Interactive E-Module Based on Inquiry Learning for Calculus Derivative Topics in Higher Education Lilla Puji Lestari; Gregorio Antonny Bani; Raveenthiran Vivekanantharasa
International Journal of Mathematics and Science Education Vol. 1 No. 3 (2024): August : International Journal of Mathematics and Science Education
Publisher : Asosiasi Riset Ilmu Matematika dan Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijmse.v1i3.254

Abstract

This research investigates the development and testing of an interactive e-module based on inquiry learning, designed to improve students’ understanding of derivatives in calculus. The study adopts a Research and Development (R&D) approach, which involves several stages: design, prototype creation, testing, and revision. The e-module incorporates interactive exercises, real-time feedback, and multimedia elements to engage students in active learning. A pre- and post-test assessment was conducted to measure the effectiveness of the e-module, revealing a 20% improvement in students’ conceptual understanding of derivatives. Feedback from students indicated that the e-module’s interactive features, including visual representations, problem-solving activities, and immediate corrections, significantly enhanced their learning experience. The results were compared with traditional printed materials, showing that the interactive e-module was more effective in improving students' problem-solving skills and overall understanding of abstract concepts in calculus. The findings suggest that technology-enhanced tools, such as interactive e-modules, offer a promising approach to calculus education, fostering deeper engagement and providing immediate feedback, which traditional methods fail to offer. These tools are particularly beneficial in bridging the gap between theoretical understanding and practical application in higher education. The study also recommends expanding the use of inquiry-based learning and interactive modules to other areas of mathematics and STEM education. Future research should focus on refining the e-module to include more personalized learning pathways and explore its long-term effects on students' performance across various subjects.
Pemanfaatan Asap Cair Berbasis Limbah Tempurung Kelapa sebagai Pengawet Alami dan Teknik Pengasapan Ikan yang Eco-Friendly Lestari, Lilla Puji; Ahsan, Faris Miftakul; Nurrochman, Muhammad Fariz; Ibrahim, Mochammad Rizki
CHEDS: Journal of Chemistry, Education, and Science Vol 9, No 2 (2025)
Publisher : Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/cheds.v9i2.12578

Abstract

Penelitian ini berawal dari tingginya penggunaan pengawet kimia berbahaya dalam makanan, sehingga diperlukan alternatif pengawet alami yang lebih aman. Tujuan penelitian ini adalah untuk menganalisis proses produksi asap cair dari tempurung kelapa dalam sistem tertutup, mengevaluasi efektivitasnya sebagai pengawet ikan, dan mengamati perubahan kualitas ikan setelah perlakuan. Metode yang digunakan meliputi produksi asap cair melalui pirolisis, kondensasi, dan pemurnian hingga grade 1, kemudian diaplikasikan pada ikan dengan berbagai konsentrasi, yaitu 0%, 2%, 4%, dan 6%. Hasil penelitian menunjukkan bahwa asap cair mengandung senyawa fenolik dan asam organik yang dapat menghambat pertumbuhan mikroba, menstabilkan pH, dan menjaga warna, aroma, dan tekstur ikan. Konsentrasi 4–6% ditemukan paling efektif. Kesimpulan dari penelitian ini adalah asap cair berbasis limbah tempurung kelapa berpotensi menjadi pengawet alami yang aman dan ramah lingkungan dibandingkan dengan pengawet sintetis.
Co-Authors Abd. Jalil Achmad Almubaroq Achmad Ony Mirza Firdiansyah Ady Lesmana Aep Saefullah Afifah, Yunita Nur Afifatuz Zakiyyah Ahmad Dani Fahrudin Ahmad Heru Romadhon Ahsan, Faris Miftakul Akbar, Ronny Makhfuddin Aldimas, Reven Alfiah Indasah ALIMA Alima Anfal Ainul Yaqin Anita Annando Kusuma Dianto Arrafi, David Khalik As’ad, Ihwana Aulia, Rizza Fatma Bambang Panji G Bambang Panji Gunawan Choifin, M Choifin, Mochamad Choifin Diah Ayu Apriani Dianto, Annando Kusuma Dony Perdana Dwi Endah Dwi Retnaningtyas Utami Eddy Gunawan Eko Nurmianto Eko Nurmianto Eko Sutrisno, Eko Endang Endang Endang Mawarti Endang Muryani Erly Ekayanti Rosyida Ersad Mochammad Evy Ratnasari Ekawati Fahmi Arti Fahmia Nur Fauziah Fahrudin, Ahmad Dani Faiz Miftahul Huda Farkhan, Muhammad Fauziah, Fahmia Nur Fikri Fauzan Nur Nurmianto Fikri Nurfauzan Nurmianto Firda Inayah Gilang Samudra Trikurniawan Gregorio Antonny Bani Ibrahim, Mochammad Rizki Ica Elvina Imun, Meri M. Indah Nur Aini Indasah, Alfiah Indriyani Indriyani Jiarti Kusbandiyah Karisma Ayu Ningtyas Keiko Alliyah Nugraha Khairil Anam Khairil Anam, Khairil Khoirul Ngibad Khoirul Ngibad Lailatun Ni’mah Laily Fazriyah Lestari, Veronika Nugraheni Sri Lidyawati, Anna Lina Maulidiana M Choifin Madani, Midhad Maghfiroh, Isnaini Ramadhani Hayyuni Margalin, Brilliant Marniati Marniati Mawarti, Endang Mei Ayu Setyo Ningrum Mitha Otik Wiraswati Mochamad Fahmi Saputra Mochamad Fahmi Saputra Mochammad Choifin Mochammad Machrudi Zakaria Mochammad Mahdi Abyan Muhammad Alfian Muzzaky Muhammad Farkhan Nadhifah Salsabila Ngibad, Khoirul Ningtyas, Karisma Ayu Nurasiah Nurasiah Nurmianto, Fikri Fauzan Nur Nurmianto, Fikri Nur Fauzan Nurrochman, Muhammad Fariz Oky Permana PAMUNGKAS, ADJI Pandey, Digvijay Prastio, Andika Yuli Puspita, Asri Dwi Rahmawati, Eka Putri Ramli, Nurlaili Raveenthiran Vivekanantharasa Renny Nirwana Sari Rezki Bachtiar Yuliansyah Rio Arisandi Pratama Rizka Mudyanti Robbi'ul Hamzah Rodli, Achmad Fathoni Romadhon, Ahmad Heru Rudy Ananta Safitri, Lailatul Safitri, Vira Salsabila, Nadhifah SARI, MULIA SAFRIDA Sari, Ratna Eka Sari, Renny Nirwana Setiawan Setiawan Setiawan Setiawan Sholikhah, Faizatus Solikah Ana Estikomah Sonny Wijaya Sonny Wijaya Sri Haryanto Sri Wahyuni Sri Wiwoho Mujanarko Sriyanti, Cut Sugianto Sutrisno Adi Prayitno Sutrisno Adi Prayitno Triyoga, Muhammad Dandi Utami, Dwi Retnaningtyas Venty Delvi Ayu Vira Safitri Wahyu Utami Wahyu Utami, Wahyu Wijaya, Sonny Wiji Lestariningsih Wilujeng Rindhyani Rahayu Winda Ayu Afrina Wujaya, Sonny Wuri Kristianto Yahya, Sitti Rachmawati Yanuarini Nur Sukmaningtyas Yuda Ryan Saputro Yuli Choirul Umah, Yuli Choirul Yulita Dwi Nor Afifah Yunita Nur Afifah Zukhruf Ramadhani Zulzilaatun Nikmah