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Journal : Medical Journal of Indonesia

Association between public knowledge regarding antibiotics and self-medication with antibiotics in Teling Atas Community Health Center, East Indonesia Kurniawan, Kurniawan; Posangi, Jimmy; Rampengan, Nancy
Medical Journal of Indonesia Vol 26, No 1 (2017): March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (405.908 KB) | DOI: 10.13181/mji.v26i1.1589

Abstract

Background: Self-medication with antibiotics increases the risk of resistance, which leads to higher morbidity and mortality. The community plays an important role in preventing and controlling the spread of antibiotic resistance. This study aims to determine factors associated with antibiotics self-medication practices in the community, which are the key to developing effective intervention programs.Methods: This cross-sectional study was conducted between September and October 2015 at Teling Atas Community Health Center in Wanea, a sub-district of East Indonesia region. Data was collected by a questionnaire-guided interview. There were 35 questions which cover respondent demographics, antibiotic use, and respondents’ knowledge about antibiotics. Logistic regression was used to analyze the association between self-medication with antibiotics and respondents’ level of knowledge as well as other factors.Results: Among 400 respondents, there were 240 (60%) who had used antibiotics within 6 months prior to the interview and 180 (45.0%) who had self-medicated. Wounds or skin diseases (32.2%) were main reasons for self-medication. The majority of respondents self-medicated on their own initiatives (70.6%) and purchased antibiotics in pharmacies (52.2%). The mean score for respondent knowledge about antibiotic was categorized as “moderate” (score 7.14±2.49). Respondents with lower knowledge scores had higher probabilities to self-medicate with antibiotics than those with higher scores (OR= 16.86; 95% CI= 4.25–66.83).Conclusion: Self-medication practices with antibiotics in this study are associated with age, family income, and knowledge. Since poorer knowledge about antibiotics is associated with a higher probability of self-medication with antibiotics, education programs to improve public awareness are needed.
Effect of enhanced external counterpulsation therapy on myeloperoxidase in lowering cardiovascular events of patients with chronic heart failure Rampengan, Starry H.; Setianto, Budhi; Posangi, Jimmy; Immanuel, Suzanna; Prihartono, Judo; Siagian, Minarma; Kalim, Harmani; Inneke, Sirowanto; Abdullah, Murdani; Waspadji, Sarwono
Medical Journal of Indonesia Vol 22, No 3 (2013): August
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (911.558 KB) | DOI: 10.13181/mji.v22i3.584

Abstract

Background: Chronic heart failure (CHF) is a slowly progressive disease with high morbidity and mortality; therefore, the management using pharmacological treatments frequently fails to improve outcome. Enhanced external counterpulsation (EECP), a non-invasive treatment, may serve as alternative treatment for heart failure. This study was aimed to evaluate the influence of EECP on myeloperoxidase (MPO) as inflammatory marker as well as cardiac events outcome.Methods: This was an open randomized controlled clinical trial on 66 CHF patients visiting several cardiovascular clinics in Manado between January-December 2012. The subjects were randomly divided into two groups, i.e. the group who receive EECP therapy and those who did not receive EECP therapy with 33 patients in each group. Myeloperoxidase (MPO) as inflammatory marker was examined at baseline and after 6 months of observation. Cardiovascular events were observed as well after 6 months of observation. Unpaired t-test was use to analyze the difference of MPO between the two groups, and chi-square followed by calculation of relative risk were used for estimation of cardiovascular event outcomes.Results: MPO measurement at baseline and after 6 months in EECP group were 643.16 ± 239.40 pM and 422.31 ± 156.26 pM, respectively (p < 0.001). Whereas in non EECP group, the MPO values were 584.69 ± 281.40 pM and 517.64 ± 189.68 pM, repectively (p = 0.792). MPO reduction was observed in all patients of EECP group and in 13 patients (48%) of non-EECP group (p < 0.001). Cardiovascular events were observed in 7 (21.21%) and 15 (45.45%) of patients in EECP and non-EECP groups, respectively (p = 0.037).Conclusion: EECP therapy significantly decreased the level of MPO as inflammatory marker and this decrease was correlated with the reduction of cardiovascular events in CHF patients. (Med J Indones. 2013;22:152-60. doi: 10.13181/mji.v22i3.584)Keywords: CHF, cardiovascular events, EECP, myeloperoxidase
Co-Authors Aaltje E. Manampiring Abdul, Jihan A. Achmad, Mardhita Nilamsari Alamri, Khairun N. H. Amelia I. Toar Anak Agung Istri Sri Wiadnyani Angela Christin Tiwa Angelina Stevany Regina Masengi Antje A Wuwungan Antonius R.B. Ola Arthur Mongan Ayu S. Gugule B H. R. Kairupan Bagaray, Evangelin Fresianly Bato, Donny Christian Bernat S. P. Hutagalung Billy J. Kepel Budhi Setianto Christy N. Mintjelungan Citra R. Irianty Clara, Santi Daniel Febrian Sengkey Dantje T Sembel Dimas Prakoso Dina Rombot Dwilestari . Edward Nangoy, Edward Edward S. Oroh, Edward S. Elisa Mangkey Esther Ariny Rumimper Eva A. Sijabat, Eva A. Faidiban, Aqueline N. Falugah, Fathia Fatimawali , Fatimawali Fatimawali . Febriana ., Febriana Frengki P. Menggelea Go Handayani, Go Gosal, Leonardo Delvin Grace D. Kandau, Grace D. Grace Debbie Kandou Gresty Masi Gustaaf A. E. Ratag Hans Huijbregts Harmani Kalim Hasanuddin, Israyati R. Hendra Sandag Henoch Awaloei Herman Warouw IC Manoppo, Jeanette IC Indriya Robot, Melisa Ira Posangi Jane Wuisan Judo Prihartono Juliatri . Julio Lopez Aban, Julio Lopez Katuuk, Mario Esau Kipimbob, Eflentina Kumala Dewi, Citra Kurnia, Bonar Kurniawan Kurniawan Laurentius Rumokoy, Laurentius Lendombela, Ditya P. J. Lengkong, Gledys Tirsa Lesar, Imelda Lidia Lidia Iswanto, Lidia Linnie Pondaag Lucia I. R. Lefrandt Mallombasang, Andi Nuraini Mamahit, Juliet Merry Eva Mambo, Christi D. Mambo, Christi Diana Manampiring, Aaltje Ellen Manannohas, Mouren Mantjoro, Eva M. Marthen Theogives Lasut, Marthen Theogives Masi, Gresty N.M. Maya Memah Mewengkang, Mario L. Michael A. Leman Minarma Siagian Mona P. Wowor Murdani Abdullah Naray, Gueen L. G. Nas Lokbere Natalia Christine Mantiri Ni Luh G.L. Jayalandri, Ni Luh G.L. Ni Wayan Mariati Nina S Widiarto Ning Irianti, Ning O. Mona Wowor Oddi R Pinontoan Olivia Waworuntu Oroh, Wenda P. Djufri, Moh Akbar P. M. Wowor P. S. Anindita Paliling, Agrianto Pandegirot, Juliana Sisca Pangouw, Excel Paulina yamlean Pemsi M. Wowor, Pemsi M. Pertiwi, Junita Maja Polii, Erfand Priska F. Umboh Putri, Vita A.D Rahadian, Rifky Aditya Ramadi, Reza Pahlevi Rampengan, Nancy Ratag, Gustaaf Regina Masengi, Angelina Stevany Ristanti Pratiwi Robert A. Bara Rondonuwu, Yohanes Amazia Zet Roring, Natalia Megawati Rudianto Tari S. Surya, Welong S. V. Sinolungan, Jehosua Saartje J Lumanauw Salsabila, Febrisa Santi Turangan, Santi Sarwono Waspadji Sirowanto Inneke Sondakh, Refrando M. Starry H. Rampengan Sunny Wangko Surya, Welong S. Suryadi N. N. Tatura, Suryadi N. N. Suryani, Intan Indah Suzanna Immanuel T. Lasut, Markus Tahulending, Jane Tangkuman, Victor Yohanes Tansil, Alberta Y.M. Tarigan, Paulus B. Titi L. Faraknimella, Titi L. V. Rombot, Dina Vastelita Lengkong, Injili Anugerah Venesia Pengan VERY LONDA Vivi P. Santoso Vonny N. S. Wowor Vonny Wowor Walewangko, Marfincy Walewangko, Marfincy S. Warouw, Finny Warouw, Inggrid Waworuntu, Waworuntu Welong, Seftian Surya Widya Astuty Lolo, Widya Astuty Wisie Lusia Toar, Wisie Lusia Wulan P. J. Kaunang Y. Tangkuman, Yundi Y. Yolanda A. Kasi Yolanda Bataha Yulianty Sanggelorang