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Uji Efektivitas Seduhan Kopi Biji Okra (Abelmoschus esculentus) terhadap Penurunan Kadar Glukosa Darah pada Mencit yang diinduksi Aloksan Zulvia Faridatul Munawaroh; Rahmat A.H. Wahid; Nurul Marfu'ah
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 3, No 2 (2019): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (481.44 KB) | DOI: 10.21111/pharmasipha.v3i2.3405

Abstract

Diabetes mellitus is a degenerative disease characterized by high blood glucose levels. Various ways that people use for treatment, herbal is one of the choices. God will not create an illness unless Him has created the medicine. One of the plants that is often used to treatment diabetes mellitus is okra plants. Okra seeds could be processed into coffee which is used as a substitute for caffeinated coffee. Based on community experience, so this research to know the effectiveness test of steeping coffee from okra (Abelmoschus esculentus) seeds in alloxan-induced diabetic mice and to know the effective concentration of steeping coffee from okra (Abelmoschus esculentus) seeds in alloxan-induced diabetic mice. This research was an experimental study. The research design used was a Completely Randomized Design (CRD) consisting of 4 treatments and 4 replications. The sample consisted of 16 male mice. The study was divided into 4 groups, The sample consisted of16 male mice and divided into 4 group, giving aquadest as a positive control (PC) while in treatment T1 by giving steeping coffee from okra seeds with a concentration of 1.82 mg/grBW/day, 3.64 mg/grBW/day for T2 and T3 with a concentration of 5.46 mg/mgBW/day for 10 days . Data were analyzed using the SPSS 16.0. According to the results of the One Way ANOVA test with a significance level of 95% were obtained at 0,000 (p = <0.05) which means that, between treatments given by okra seeds coffee, okra seeds coffee were effective against blood glucose levels of mice after alloxan was induced. Based on the three treatments for the administration of okra seeds coffee with various concentrations, group T3 (5.46 mg/mgBW/day) with a significance value of 0,000 (p<0.05) which was the most effective for reducting blood glucose levels in alloxan-induced diabetic mice.
EVALUASI PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN IBU HAMIL DI INSTALASI RAWAT INAP RSIA MUSLIMAT JOMBANG TAHUN 2018 Siska Fatkhul Hidayati; Yulia Dwi Andarini; Nurul Marfu&#039;ah
Pharmasipha: Pharmaceutical Journal of Islamic Pharmacy Vol 4, No 2 (2020): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v4i2.4959

Abstract

Penyakit hipertensi dalam kehamilan sampai saat ini masih merupakan masalah dalam pelayanan obstetri di negara Indonesia. Penelitian ini bertujuan untuk mengetahui dan memahami profil penggunaan obat antihipertensi pada pasien hipertensi dalam kehamilan di Instalasi Rawat Inap Rumah Sakit Ibu dan Anak (RSIA) Muslimat Jombang. Tujuan khusus dalam penelitian ini yang ingin dicapai adalah untuk mengetahui karakteristik pasien hipertensi dalam kehamilan, jenis dan golongan obat, jumlah obat antihipertensi yang digunakan, cara pemberian obat, tepat indikasi pasien, tepat obat pasien dan tepat dosis pasien. Penelitian ini termasuk penelitian deskriptif secara observasional non eksperimental. Data yang digunakan dalam penelitian ini adalah data retrospektif dengan melakukan penelusuran data rekam medik pasien hipertensi pada ibu hamil di Instalasi Rawat Inap Rumah Sakit Ibu dan Anak Muslimat Jombang tahun 2018. Data yang diambil meliputi data pasien dan data obat yang digunakan oleh pasien. Dari hasil penelitian diperoleh kasus hipertensi dalam kehamilan sebanyak 40 pasien, pasien yang mendapat terapi obat antihipertensi sebanyak 32,5 % dan pasien yang tidak mendapat terapi obat antihipertensi sebanyak 67,5% menunjukkan ketepatan indikasi berdasarkan standar Queensland Health (Hypertensive Disorders of Pregnancy). Pada penelitian ini pasien yang mendapat terapi obat antihipertensi jenis Furosemid sebanyak 23% dan yang mendapat terapi obat antihipertensi jenis Nifedipin sebanyak 77% menunjukkan ketepatan obat berdasarkan standar Queensland Health (Hypertensive Disorders of Pregnancy). Dari data yang dianalisis di dapatkan bahwa dosis terapi obat antihipertensi jenis Furosemid sebanyak 20-80 mg dan dosis terapi obat antihipertensi jenis Nifedipin sebanyak 5-20 mg juga menunjukkan tepat dosis sesuai standar Queensland Health (Hypertensive Disorders of Pregnancy).
Formulasi Sediaan Sabun Cair Ekstrak Daun Sirih Hijau (Piper battle folium L.) dan Ekstrak Bawang Putih (Allium sativum L.) sebagai Antijamur Candida albicans Rohmah Madya Ayu Fitriana; Solikah Ana Estikomah; Nurul Marfu&#039;ah
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 2, No 2 (2018): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (382.288 KB) | DOI: 10.21111/pharmasipha.v2i2.3040

Abstract

Islam is a religion that likes cleanliness, in case of body hygiene, clothing, and environment. One of the diseases that arise because it does not keep the body clean is white discharge. Piper bettle folium and Alium sativum are some of the natural ingredients that has the potential as an antifungal. This research aims to see the effect of antifungal Candida albicans extract of Piper bettle folium and Alium sativum after formulated as a liquid soap preparation. Liquid soaps are made by hot process methods with 3 formulations of combination of Piper bettle folium and Alium sativum extract with a ratio of 1) 25%: 75% 2) 50%: 50% 3) 75%: 25%. The evaluation of liquid soap include organoleptic examination, pH, high foam, moisture content, homogeneity, and antifungal power test against Candida albicans fungus. The results of the testing of liquid soap quality of green betel leaf extract and garlic have met the standards SNI (Indonesia’s National Standards) set for the manufacture of liquid soap.The results showed that liquid soap extract of green betel leaf and garlic have antifungal activity against Candida albicans. The result of formulation with the highest inhibition zone is formulation 3 and formulation with the lowest inhibition zone is the formulation 1. The test of this liquid soap activity is higher than fluconazole as the positive control and liquid soap of female area spread in the market.
FORMULASI MASKER GEL PEEL-OFF EKSTRAK BEKATUL PADI BERAS MERAH (Oryza nivara) Ava Zaujah; Andi Sri Suriati Amal; Nurul Marfu&#039;ah
Pharmasipha: Pharmaceutical Journal of Islamic Pharmacy Vol 4, No 1 (2020): Maret
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v4i1.3946

Abstract

Ekstrak bekatul padi beras merah dapat dimanfaatkan dalam formulasi sediaan masker gel peel-off. Kandungan senyawa bioaktif yang terdapat dalam bekatul seperti flavonoid, fenolik, gamma oryzanol, dan antosianin merupakan senyawa yang dapat berfungsi sebagai antioksidan. Bekatul padi beras merah merupakan salah satu alternatif untuk mengatasi efek buruk yang ditimbulkan oleh radikal bebas. Penelitian ini dilakukan untuk memformulasikan bekatul padi beras merah dalam bentuk sediaan masker gel peel-off. Ekstraksi bekatul padi beras merah dilakukan dengan metode maserasi menggunakan perarut etanol 96%. Formulasi masker gel peel-off ekstrak bekatul padi beras merah terdiri dari polivinil alkohol (PVA) 8%, Hidroxy Propyl Methyl Cellulose HPMC 1%, madu 3%, propilenglikol 2%, nipagin 0,02%, air suling dan penambahan ekstrak bekatul padi beras merah dengan konsentrasi berbeda pada masing-masing formula (F) yaitu F1 (5%), F2 (10%) dan F3 (15%). Ketiga formula masker gel peel-off ekstrak bekatul padi beras merah berwarna kuning kecoklatan, merah kecoklatan hingga coklat kemerahan, beraroma madu, dan berbentuk cairan kental dengan rata-rata nilai viskositas 2974,9-15000 Cps, pH 5,4-5,1, daya sebar 5,4-5 cm, waktu mengering 30 menit dan elastisitas 8,8-6 cm.
UJI EFEKTIVITAS KOMBINASI EKSTRAK BUAH LABU AIR (Lagenaria siceraria) DAN RIMPANG KUNYIT (Curcuma domestica) SEBAGAI ANTIBAKTERI Salmonella typhi SECARA IN VITRO Lutfi Shantia; Nurul Marfu’ah; Rizki Awaluddin
Pharmasipha: Pharmaceutical Journal of Islamic Pharmacy Vol 5, No 1 (2021): Maret
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (359.628 KB) | DOI: 10.21111/pharmasipha.v5i1.4298

Abstract

Salmonella typhi merupakan bakteri gram negatif yang menyebabkan demam tifoid (tifus), yaitu penyakit infeksi yang menyebar keseluruh tubuh ditandai dengan demam panjang. Terapi penyembuhan untuk tifus dilakukan dengan terapi pemberian antibiotik, salah satunya adalah kloramfenikol. Beberapa waktu terakhir, bakteri Salmonella typhi menjadi resisten terhadap kloramfenikol, ampisilin dan trimethropim-sulfamethoxazole. Penelitian ini dimaksudkan untuk meneliti tanaman herbal sebagai antibakteri Salmonella typhi. Tanaman yang akan diuji adalah ekstrak etanol buah labu air dan rimpang kunyit dengan konsentrasi tunggal dan kombinasi sebagai antibakteri Salmonella typhi secara in vitro. Perlakuan dibagi menjadi 7 kelompok yang terdiri dari, kontrol positif (Kloramfenikol), kontrol negatif (CMC Na 1%), kombinasi 0%:100%; 75%:25%; 50%:50%; 25%:75%; dan 100%:0%. Data analisis menggunakan uji statistik non parametrik Kruskall-Wallis. Berdasarkan penelitian yang dilakukan didapat hasil zona hambat dengan rentan nilai rata-rata 0-1 mm. Kombinasi ekstrak etanol buah labu air 100% dan rimpang kunyit 0% menghasilkan zona hambat paling besar dibandingkan kombinasi lain yaitu sebesar 1,25 mm (respon hambat lemah).
Pengaruh Puasa Terhadap Tekanan Darah Sistol Dan Diastol Pada Pria Muda Nurul Marfuah; Lija Oktya Artanti
2-TRIK: TUNAS-TUNAS RISET KESEHATAN Vol 9, No 4 (2019): November 2019
Publisher : FORUM ILMIAH KESEHATAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/2trik9408

Abstract

People who have high blood pressure (hypertension) if it lasts for a long time will cause kidney, heart disease and stroke. Therefore, the purpose of this study is to determine the effect of fasting on systole and diastolic blood pressure in young men. This study was an experiment using 10 young men subjects aged 20-23 years old divided into 5 treatment groups namely (A) No fasting, (B) fasting yaumul bidh, (C) fasting Monday-Thursday, (D) fasting Dawood, and (E) fasting every day. The treatment was carried out for 37 days. Data collection in the form of blood pressure measurements carried out before and after treatment using a tensimeter. The data obtained were analyzed using one-way ANOVA and paired sample T tests with a significance level of 5% using SPSS 16.0. The results showed that there was a decrease in average blood pressure in both systole and diastole after fasting, although statistically the difference was not significant (P>0.05). Keywords: fasting; blood pressure; systole diastole; young men ABSTRAK Orang yang terlanjur memiliki tekanan darah tinggi (hipertensi) apabila berlangsung dalam waktu lama akan menyebabkan penyakit ginjal, jantung dan stroke. Oleh karena itu, tujuan penelitian ini adalah untuk mengetahui pengaruh puasa terhadap tekanan darah sistol dan diastol pada pria muda. Penelitian ini merupakan eksperimen menggunakan subyek pria muda berusia 20-23 tahun sebanyak 10 orang dibagi ke dalam 5 kelompok perlakuan yaitu (A) Tidak puasa, (B) puasa yaumul bidh, (C) puasa Senin-Kamis, (D) puasa Daud, dan (E) puasa setiap hari. Perlakuan dilaksanakan selama 37 hari. Pengambilan data berupa pengukuran tekanan darah dilakukan sebelum dan sesudah perlakuan menggunakan tensimeter. Data yang diperoleh dianalisis menggunakan one-way ANOVA dan paired sample T test dengan taraf signifikansi 5% menggunakan SPSS 16.0. Hasil penelitian menunjukkan bahwa terjadi penurunan rata-rata tekanan darah baik sistol maupun diastol sesudah melakukan puasa meskipun secara statistik perbedaan tersebut tidak signifikan (P > 0,05). Kata kunci: puasa; tekanan darah; sistol diastol; pria muda
Analisis Kualitatif dan Kuantitatif Kandungan Hidrokuinon dalam Krim Pemutih Wajah yang Beredar di Pasar Tradisional Kabupaten Blora Jawa Tengah Hamzah Gita Sari; Nurul Marfu&#039;ah; Nadia Saptarina
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 6, No 1 (2022): Maret
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v6i1.8700

Abstract

Beautifying self with cosmetics is one of the ways that people interested. Consumer demand for face whitening cream is so high that many manufacturers market non-certified products containing harmful ingredients such as hydroquinone. In BPOM Regulation No. 23 of 2019 the use of hydroquinone in skin whitening is no longer allowed. Whitening cream is spread in traditional markets where a place to buy and sell various of products freely. This study aims to find out whether or not hydroquinone and its content in face whitening creams are circulating in the traditional market of Blora Regency. Sampling using pusposive sampling technique in the traditional market of Blora Regency. Samples obtained from 4 traditional markets as many as 8 samples consist of 4 samples with registration number BPOM (codes A, B, C and D) and 4 samples without registration number BPOM (codes E, F, G and H). Hydroquinone content examination includes qualitative analysis with pH measurement, color reagent and TLC and quantitative analysis with UV Spectrophotometry. The results of the hydroquine standard pH measurement showed an acid pH of 3.53-3.64 positive samples i.e. E-H samples ranging from 3.30-3.64. In the color reaction hydroquinone formed a black color with sediment, and in TLC obtained a hydroquinone Rf value of 0.9610 with a positive sample Rf value ranging from 0.9444-0.9610 so that the positive result of hydroquinone in the E-H sample. Quantitative analysis using UV Spectrophotometry showed hydroquinone levels in non BPOM code samples E, F, G and H ranging from 0.00123 % - 0.00178 %.
Pengaruh Variasi Humektan pada Formulasi Hand Sanitizer serta Evaluasi Sediaan dan Daya Hambat terhadap Stapyhlococcus aureus Qurrah A&#039;yuniyyah Haryanto; Kurniawan Kurniawan; Solikah Ana Estikomah; Nurul Marfu&#039;ah
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 6, No 2 (2022): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v6i2.7572

Abstract

The habits of the Indonesian people in carrying out hand hygiene activities are still very low with an average of only 12%. Along with the density of community activities, which consider hand washing a troublesome activity, it is also caused by the lack of clean water availability in the community. Therefore, there are hand sanitizer products that are practical without using water or commonly referred to as hand sanitizers. Hand sanitizer contains antiseptic substances that can kill germs on the palms due to the presence of alcohol (ethanol, propanol and isopropanol) and the phenol group (chlorhexidine and triclosan). Alcohol has the ability to inhibit bacterial growth, both against gram-positive and gram-negative bacteria, including MRSA (Methicilin Resistant of Staphylococcus aureus). The purpose of this study was to determine the effect of humectant variations on the evaluation of the preparation and the inhibition of Staphylococcus aureus bacteria. The results of the evaluation of the preparation of the hand sanitizer formulation are in accordance with the SNI No. 06-2588-1992, namely on the parameters of homogeneity, pH and dispersion. Meanwhile, the viscosity parameter is not in accordance with the standard. Variations in humectant concentration affect the evaluation of the preparation of the hand sanitizer gel formulation on the parameters of pH and dispersion. The formulation that had the greatest inhibition zone against Staphylococcus aureus was the formulation with the highest humectant concentration of propylene glycol, namely formulation 3 with an inhibitory power of 22.8 mm.
Penyuluhan Kesehatan Reproduksi dan Pelatihan Senam Dismenore Santriwati Pondok Gontor Putri 2 Mantingan, Ngawi Nurul Marfu'ah; Amilia Yuni Damayanti; Indah Tri Lestari
Janaka, Jurnal Pengabdian Masyarakat Vol 4 No 1 (2021): November 2021
Publisher : LP3M STAI Darussalam Krempyang Nganjuk

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29062/janaka.v4i1.314

Abstract

Lack of knowledge about women's reproduction health causes santriwati to experience several problems, such as menstrual pain (dysmenorrhea). The purpose of this activity is a) to increase knowledge about women's reproduction health, b) to help respondents overcome dysmenorrhea by doing exercise. Respondents used were 342 santriwati. The method used is counseling about women's reproduction health. Before the counseling, the respondents' knowledge level about reproduction health consisted of Very Good (84.50%) and Good (15.50%). After the counseling, 100% of the respondents knew Very Good about reproduction health knowledge, especially material about menstruation, pregnancy, postpartum, breastfeeding, infertility, IVF and cloning. While the dysmenorrhea exercise training carried out showed the results that before the training, the level of knowledge of the respondents regarding the existence of dysmenorrhea exercise consisted of Good (2.34%), Less Good (26.31%) and Very Good (71.35%) but they could not practice it. After training, 99.71% of respondents know and can practice dysmenorrhea exercise Very Good.
THE EFFECT OF MONDAY THURSDAY FAST HABITS ON GLUCOSE, CHOLESTEROL, AND URIC ACID IN YOUNG ADULT WOMEN Nurul Marfu'ah; Zulianita Zulianita; Amal Fadholah; Khomarul Kuniyati; Sujiat Zubaidi
International Journal of Islamic and Complementary Medicine Vol. 3 No. 2 (2022): International Journal of Islamic and Complementary Medicine
Publisher : International Islamic Medicine Forum

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55116/IJICM.V3I2.48

Abstract

Excess levels of glucose, cholesterol, and uric acid can cause health problems called hyperglycemia, hypercholesterolemia, and hyperuricemia. It is better to take preventive measures than to treat patients who have been exposed to the disease. One of the preventive measures is to fast on Mondays and Thursdays when they are still younger. By fasting, food intake will be controlled so that hyperglycemia, hypercholesterolemia, and hyperuricemia can be avoided. Based on this background, this study aims to determine the effect of sunnah fasting on Mondays and Thursdays on glucose, cholesterol, and uric acid levels in young adult women. This study is an experimental study with two treatment groups, namely the group that is accustomed to fasting sunnah Monday and Thursday for 6-12 months and the group that is not accustomed to fasting as a control. The research subjects were 40 students of University of Darussalam Gontor Female, Mantingan Campus, Ngawi, East Java which were divided into 2 treatment groups. Research subjects have an age range of 19-23 years, weight 40-65 kg, and height 145-165 cm. Measurement of glucose, cholesterol and uric acid levels was carried out once on research subjects using the Easy Touch GCU tool. Analysis of the data used is the Independent-T Test with a significance level of 95% using the SPSS 16.0 statistical program. The results showed that blood glucose levels in the group of young women who were accustomed to fasting were lower than the control group (young women who were not accustomed to fasting). Meanwhile, cholesterol and uric acid levels in the group of young women who were accustomed to fasting were higher than the control group (young women who were not accustomed to fasting). Although this difference was not statistically significant (p > 0.05).
Co-Authors Al Hasanah, Fauziyyah Alifya Nur Azizah Amal Fadholah Amala, Nur Amilia Yuni Damayanti Ananda, Mutiara Andi Sri Suriati Amal Andri Karin, Elsy Juni Anjani, Hanifa Dyanti Anugerah Suciati Astuti, Eti Aural Miftahul Hasanah Ava Zaujah Awaluddin, Rizki Ayu, Gustin Swastika Azzahra, Isma Chelsea Aulia Ramadhani Cisilliya Tandraini Damayanti, Widya Dewi Ratnasari Diah Ayu Mutmaina Dianti Desita Sari Diwana, Nida Khofiya Puspa Eva Nor Diana Lestari Fajri, Mathla’il Fardyatullail, Haila Farhana, Siti Awalisanah Hani Fauziatunnisa, Elok Fazriah D., Gita Fitrian, Ahyana Frida SA, Yuna Hafifah, Cut Ajma Fitira Hamzah Gita Sari Hartinah Yulianto, Siti Haryanto, Qurrah A'yuniyyah I Wayan Kasa Ichwanuddin Ichwanuddin Indah Tri Lestari Indahtul Mufidah Khodijah, Alisya Khomarul Kuniyati Kurniawan Kurniawan Kurniawan Kurniawan, Kurniawan Kusumasary, Dhiyah Ayu KW, Faradhita Lestari, Eva Nor Diana Lia, Melda Lija Oktya Artanti Lija Oktya Artanti Lutfi Shantia Luthfiya, Lulu' Luthfiya, Lulu’ Mafazatien Nailiyah Isna Mahirotun NS, Anggun Mahmudah, Amalia Nurul Mahmudah, Hilma Radhia Mathlail Fajri Maulia Isnaini MIFTAKHUL JANNAH Mira Dian Naufalina Mira Dian Naufalina Muhammad El Riza NA, Eldyamarta Nadia Iha Fatihah Nadia Mira Kusumaningtyas Nadia Saptarina Nadia Saptarina Nida Faradisa Fauziyah Nisrina, Salma Nur Hazlia, Syarifah Pertamana, Ropia Pibriyanti, Kartika Pratiwi, Arika Putri Putri, Kayla Radina Dwi Qurrah A&#039;yuniyyah Haryanto Rabbaniyah, Muthi’ah Rahmat A Hi Wahid Rahmat A.H. Wahid Rauf, Ichsan Riyani, Retno Indra Riza Amalia Riza, Muhammad El Rizka Safira Rizki Awaluddin Rizki Awaluddin Rizky Dila Khairunnisa Rohmah Madya Ayu Fitriana Sagun Chandra Yowani Salma, Rahimia Nuzula Sari, Dianti Desita Sari, Nandita Aprilia Satwika Budi Sawitri Sawitri, Satwika Budi Sha’sha’ Luthfiana Shifa Syururin, Wakhidatus Sholihatin, Binti Siska Fatkhul Hidayati Siska, Awenda Siti Awalisanah Hani Farhana Sitti Hijraini Nur Solikah Ana Estikomah Sujiat Zubaidi Sulikhah, Novia Anggreani Surya Amal Susi Nurohmi Tri Harianto Wafa Aufia Wahid, Rahmat A Hi Wahid, Rahmat A Hi Widayanti, Erna Desi Widyaratna, Indriyanti Winati, Dian Eska Yulia Dwi Andarini Yuwono, Ratna Rahajeng Putri Zulianita Zulianita Zulvia Faridatul Munawaroh