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All Journal Bioma : Berkala Ilmiah Biologi IBDA` : Jurnal Kajian Islam dan Budaya Journal of Tropical Soils Jurnal Pengajaran MIPA Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Dimas: Jurnal Pemikiran Agama untuk Pemberdayaan Indonesian Journal of Forestry Research Jurnal Penelitian Hasil Hutan Jurnal Tanaman Industri dan Penyegar Jurnal Pengajaran Matematika dan Ilmu Pengetahuan Alam Journal of Mathematical and Fundamental Sciences VIVID Journal of Language and Literature BioCONCETTA BERITA BIOLOGI JURNAL BIOLOGI INDONESIA JURNAL HAMA DAN PENYAKIT TUMBUHAN TROPIKA Jurnal Penelitian Pertanian Terapan Unnes Science Education Journal Metodik Didaktik Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Bioedukatika EnviroScienteae Buletin Sumber Daya Geologi JMBI UNSRAT (Jurnal Ilmiah Manajemen Bisnis dan Inovasi Universitas Sam Ratulangi) Jurnal Informatika Universitas Pamulang Jurnal Agrotek Tropika Assimilation: Indonesian Journal of Biology Education JURNAL ILMIAH MAHASISWA AGROINFO GALUH JSiI (Jurnal Sistem Informasi) Jurnal Pengembangan Riset dan Observasi Teknik Informatika Astonjadro Metalurgi INAQUE: Journal of Industrial & Quality Engineering PREPOTIF : Jurnal Kesehatan Masyarakat Mumtaz: Jurnal Studi Al-Quran dan Keislaman Perspektif, Review Penelitian Tanaman Industri jurnal ilmu keolahragaan Wood Research Journal : Journal of Indonesian Wood Research Society Wood Research Journal : Journal of Indonesian Wood Research Society These proceedings represent the work of researchers participating in The International Conference on Elementary Education (ICEE) which is being hosted by the Elementary Education Study Programme School of Postgraduate Studies, Universitas Pendidikan International Journal on Social Science, Economics and Art Jawda: Journal of Islamic Education Management juremi: jurnal riset ekonomi Informatics and Computer Engineering Journal Indonesian Research Journal on Education Jurnal Dialektika Hukum Jurnal Manajemen Sistem Informasi Tadris al-'Arabiyyah: Jurnal Pendidikan Bahasa Arab dan Kebahasaaraban Al-Jadwa: Jurnal Studi Islam Jurnal Pendidikan IPA Indonesia Indonesian Journal of Forestry Research Jurnal Pendidikan MIPA
Saefudin Saefudin
Jurusan Pendidikan Biologi FPMIPA UPI
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Journal : Indonesian Journal of Forestry Research

 1 
EFFECT OF SAPPAN WOOD (Caesalpinnia sappan L) EXTRACT ON BLOOD GLUCOSE LEVEL IN WHITE RATS Saefudin, Saefudin; Pasaribu, Gunawan Trisandi; Sofnie, Sofnie; Basri, Efrida
Indonesian Journal of Forestry Research Vol. 1 No. 2 (2014): Indonesian Journal of Forestry Research
Publisher : Association of Indonesian Forestry and Environment Researchers and Technicians

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59465/ijfr.2014.1.2.109-115

Abstract

Sappan wood or kayu secang (Caesalpinia sappan L.) was reported of having medicinal properties, such as natural antioxidant, relieve vomiting of blood, and mix of ingredients for malaria drugs. The research was conducted to study the influence of ethanol extract from sappan wood on blood glucose level of white rats. The study of the blood glucose level in rats was carried out by using glucose tolerance method. It was measured by Refloluxs (Accutrend GC) with Chloropropamide 50 mg/200 g BW (Body weight) as positive control. The ethanol extracts were used in various concentrations 10, 20, 30, 40 and 50 mg/200 g BW per-oral and was observed every hour, beginning one hour before to 7 hours after the extract being administered. The results showed that treatment of ethanol extract of sappan wood by administer doses gave remarkable effect on the blood glucose level in white rat. It reduced the glucose level in the blood compared to the negative and positive control. Treatment of dose 30 mg/200 g BW gave similar effect to positive controls, while a dose of 50 mg/200 g BW gave lower blood glucose level (93 mg/dl) than the positive controls.
ANTIOXIDANT ACTIVITY AND TOXICITY EFFECT OF ELEVEN TYPES OF BARK EXTRACTS ACQUIRED FROM EUPHORBIACEAE Saefudin, Saefudin; Basri, Efrida; Sukito, Agus
Indonesian Journal of Forestry Research Vol. 5 No. 2 (2018): Indonesian Journal of Forestry Research
Publisher : Association of Indonesian Forestry and Environment Researchers and Technicians

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59465/ijfr.2018.5.2.133-146

Abstract

The use of natural antioxidants for medicinal purposes deserves thorough attention for their efficacy and possibly adverse toxicity. This paper studies the antioxidant actions and toxicity effects of bark extracts. The study focuses on eleven tree species of Euphorbiaceae family. Initially, bark samples from those trees were extracted using ethanol. The acquired extracts were examined for peroxide values with iodometric method. The bark extracts were chemically screened for possible antioxidant-compound contents, i.e. polyphenols, flavonoids, and saponins; and followed by oxidation-reduction test to assess the extract ability in vitro to scavenge free radicals in their standard sources, i.e. 2,2-diphenyl-1-picrylhydrazyl; altogether to determine qualitatively which species origin from bark extracts afforded the most potential as antioxidants. Toxicity test was performed on those bark extracts to assess their safety on living creatures, particularly humans as tried on shrimp larvae by counting their death, using the Brine Shrimp Lethality Test method. Results show that bark extracts of four plant species, i.e. Acalypha hispida Blume, Bischofia javanica Blume, Glochidion arboreum Blume and Sapium baccatum Roxb species afforded potentiality as antioxidants, because its peroxide value (POV) was lower than or somewhat above those of the positive control vitamin E (POV 89.45 μg/ml). However, bark extracts from Euphorbia antiquorum L, Euphorbia hirta L, and Jatropha podagrica Hook (i.e. LC50 : 238.85; 228.11 & 194.51 μg/ml) were highly toxic, because their LC50’s value< 1000 μg/ml.
Co-Authors A.A. Ketut Agung Cahyawan W Abdurachman Abdurachman Adi Rahmat Adyatama, Aqil Agus Sukito Al Masyhuri, Amin Alfaris, Razib Ikbal Alkayisy, Muhammad Ilyas Anharudin, Anharudin Aprih Santoso Apriliani, Nurul Ilma Ari Widodo Arif Dwi Saputra Ariyani, Ariyani Baharuddin, Rahmat Bambang Eka Tjahjana Bambang Supriatno Budiarjo, Budiarjo cahyo, farhan cahyo, farhan Chairul Chairul Chamami, M Rikza Chusni Ansori DANIMIHARDJA, S. Dewi Listyati Didik Priyandoko Dipratama, Garda Muhammad Fadhillah DN, Septian Edi Wardiana Edriani, Tiara Shofi Edy Soewono Efri, Efri Efrida Basri Eka Handayani Fajri, Barlian Fauziah, Farida Fernando, Donny Firdaus, Fazri Fudholi, Dhomas Hatta Gres Maretta, Gres Gunawan Pasaribu Gunawan Trisandi Pasaribu, Gunawan Trisandi Gunito, Heru Hamim Sudarsono . Hasni Dyah Kurniawati Amin Wahyudi, Hasni Dyah Kurniawati hastika, asyah dwi Hening Triandika Rachman I Dewa Gde Mayun Permana I GEDE SWIBAWA, I GEDE Iing Sobari Iman, Aziz Nurul Indriani, Rosa Irwan Irwan Joko Dwi Mulyanto Joko Prasetyo Junaedi Junaedi Kamaludin, Ahmad Kaneko, Nobuhiro Khairani, Intan Kristina, Anastasia Kusnadi Kusnadi Lilit Rusyati Mada, Ratu Dea Maemonah, Maemonah Mafruhah, Okti Ratna Maftuha, Mahda Rizqina Miranti Ariyani Mochammad Imron Awalludin Mr Amprasto Mufidah, Zunanik Muhammad Agus Muljanto Muhammad Irkham Firdaus N., Tina Safaria Naharani, Ita Najira Najira, Najira Nana Heryana Nisa, Ummu Khairun Nono Sutarno Nurbait, Syifa NURIL HIDAYATI Nururrahmani, Azmah Nurwati Hadjib Nuryani Rustaman Pari, Rohmah Permana, Ari Pranata, Heru R. Santosa R. Sapto Hendri Boedi Soesatyo Ragil Wijianto Ragil, Ragil Wijianto Raharto, Raharto Rahmansyah, Dicky Rahmat Baharudin Rian Kurnia, Rian Riandi Riandi Rifky Fauzi Rini Solihat Rizka, Nela RR. Ella Evrita Hestiandari Rulhendri Rulhendri Rusdi Evizal Sakinah, Rinrin Sakiroh Sakiroh Saputra, Muhamad Jaya Sari, Mutiara Dian Senopati, Galih SETYOWATMNDARTO, N. Sholahuddin, Affan Sholih, Muhammad Badrus Sholihah, Uswatun Siahaan, Kondar Siddiq, Muhamad Nur Sigit Saptono Sofnie Marusin Sofnie Sofnie Sri Haryani Styaningrum, Amalia Suandi, Muhamad Suci Wulandari Sudarsono Sudi Pramono . Sudrajat Sudrajat Sukamto, L Agus Sunaryo Sunaryo Sundjono, Sundjono Susandi, Diki Susilo, Fransiscus Xaverius Suwandi, Tri Syamsudin Syamsudin SYARIF, F. Tina Safaria Nilawati Tri Gunarsih Tri Maryono Tri Suwandi Utami, Riani Utriweni Mukhaiyar Vitta Yaumul Hikmawati Widiyastuti, Suciati Rahayu Widowati, Sri Yuni Yulius Ferry Yundari, Yundari Zidan, Zuliande