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ANALISIS HEALTH RELATED QUALITY OF LIFE (HRQOL) TERHADAP TINGKAT KEPATUHAN TERAPI ANTI HIPERTENSI PADA PASIEN GAGAL JANTUNG DI RUMAH SAKIT UNHAS Yuliana, Dewi; Poyizar, Poyizar; Emelda, Andi
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i1.26173

Abstract

Penyakit jantung merupakan salah satu masalah kesehatan utama yang menjadi penyebab kematian nomer satu di dunia. Di negara berkembang seperti Indonesia penyakit gagal jantung berhubungan erat dengan hipertensi.  Analisis kualitas  terapi antihipertensi terhadap kepatuhan pasien terhadap HRQoL pasien gagal jantung kongestif di  Rumah Sakit Unhas. Tujuan dalam penelitian ini adalah untuk mengetahui dampak terapi antihipertensi dan tingkat kepatuhan pasien terhadap HRQoL pasien gagal jantung kongestif di  Rumah Sakit Unhas. Penelitian ini mengunakan Metode Kuantitatif. Populasi dalam penelitian ini adalah pasien gagal jantung yang mendapatkan terapi anti hipertensi di Rumah Sakit UNHAS sebanyak  50 responden. Teknik pengumpulan data menggunakan instrument kuesioner dan rekam medis pasien. Metode analisis data menggunakan analisis Univariat, analisis Bivariat dan analisis Multivariat. Hasil peneltian ini, diperoleh hasil yaitu umur  tidak berhubungan terhadap tingkat kepatuhan terapi anti hipertensi pada pasien gagal jantung di Rumah Sakit UNHAS, sedangkan pendidikan  berhubungan terhadap tingkat kepatuhan terapi anti hipertensi pada pasien gagal jantung di Rumah Sakit UNHAS, demikan pula status Nikah dan pengawasan minum obat berhubungan terhadap tingkat kepatuhan terapi anti hipertensi pada pasien gagal jantung di Rumah Sakit UNHAS. Kesimpulan penelitian ini adalah adanya hubungan kepatuhan terhadap kualitas hidup pasien gagal ginjal dengan terapi hipertensi yang dipengaruhi oleh pendiddikan, status perkawinan dan pengawasan minum obat
Patient Experience: Innovating the Application of LAFKI Concept in Person-Centred Care at Healthcare Facilities Rumintjap, Friedrich M; Wahyudi, Ahyar; Meher, Cashtri; Yuliana, Dewi; Yuwanto, Listyo
Formosa Journal of Science and Technology Vol. 3 No. 4 (2024): April 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v3i4.8843

Abstract

This study evaluates the implementation of the Indonesian Healthcare Facility Accreditation Agency (LAFKI)'s Person-Centred Care (PCC) principles in healthcare settings. Focusing on patient experiences, the research addresses the effectiveness of PCC practices in enhancing health outcomes and patient satisfaction. The methodology employed involves a quantitative descriptive design, gathering data through questionnaires distributed via Google Forms to participants selected through purposive sampling from hospitals, clinics, and puskesmas. Findings indicate that while a majority of patients felt treated as unique individuals, a significant gap exists in respecting cultural values and beliefs during the decision-making process. The study highlights the need for healthcare providers to improve cultural sensitivity and patient engagement to bridge the ideological and practical implementation of PCC. The research contributes to the empirical literature by identifying barriers to effective PCC implementation and offering evidence-based recommendations for healthcare facilities to enhance their services. This aligns with LAFKI's goal of not just meeting but exceeding standards in providing holistic, person-centred care.
PENGARUH EKSTRAK DAUN BIDARA DAN DAUN GINSENG JAWA TERHADAP GAMBARAN MAKROSKOPIK GINJAL JANTUNG DAN HATI TIKUS HIPERTENSI Yuliana, Dewi; Syuhada, Anugerah Putri; Syam, Andi Suci Alfira; Putri, Nurlaila; Aulia, Vivi; Ang, Dynasti Kelani; Emelda, Andi
As-Syifaa Jurnal Farmasi Vol 17, No 1 (2025): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v17i1.1328

Abstract

Hypertension, or high blood pressure, is a condition characterized by a sustained increase in blood pressure, exceeding the normal value of ≥140/90 mmHg. Hypertension therapy aims to lower both systolic and diastolic blood pressure to restore normal levels and minimize the risk of complications. The use of herbal plants such as bidara leaves (Ziziphus mauritiana L.) and Javanese ginseng (Talinum paniculatum (Jacq.) Gaertn.) holds potential as an alternative in the management of hypertension. Medicinal plants and plant-derived compounds can exhibit various toxicological effects, including renal, cardiac, and hepatic toxicity. This study aims to investigate the effects of Bidara leaf extract and Java ginseng leaf extract on the macroscopic appearance of the kidneys, heart, and liver of prednisone-induced hypertensive rats. The study used 20 rats divided into five groups: negative control (Na-CMC 1%), positive control (Captopril 25 mg), and three groups receiving combined doses of bidara leaf and Javanese ginseng leaf ethanol extracts (EEBG 50+50 mg/kgBW, EEBG 100+100 mg/kgBW, EEBG 200+200 mg/kgBW). The results showed that the combination extract of Bidara leaves (Ziziphus mauritiana L.) and Ginseng leaves (Talinum paniculatum (Jacq.) Geartn.) at doses of 50+50, 100+100, and 200+200 mg/kgBW did not cause any macroscopic changes. Macroscopic observations showed that the kidneys, hearts, and livers of mice administered EEBG maintained a reddish-brown color with a firm consistency and smooth surface
Gambaran Pengetahuan Masyarakat Terhadap Penggunaan Analgesik OTC (Over The Counter) Di Kecamatan Wawonii Timur Kabupaten Konawe Kepulauan Provinsi Sulawesi Tenggara Yuliana, Dewi
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 4 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i4.79

Abstract

Analgesics are substances or drugs that can be used to reduce pain without losing consciousness. This drug is the most widely used type of drug in self-medication in society. This study aims to describe the knowledge of the people of East Wawonii District, Konawe Islands Regency, Southeast Sulawesi Province. This research was conducted by giving questionnaires to respondents, namely the people in East Wawonii District, Konawe Islands Regency, which then collected data and analyzed it descriptively. The sampling method used was purposive sampling and the number of samples was calculated using the slovin formula. The results showed that people in East Wawonii District, Konawe Islands Regency, Southeast Sulawesi Province already had knowledge that was included in the fairly good category regarding the use of OTC (Over The Counter) analgesics with a percentage of 73%.
Literature Review : Perkembangan Pengobatan Kemoterapi Kanker Payudara Yuliana, Dewi; Wulan, Wulan
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.133

Abstract

Breast cancer is a condition where cells lose control and normal mechanisms, resulting in abnormal, fast and uncontrolled cell growth that occurs in the breast. Breast cancer is the most feared disease by women. One of the treatments is chemotherapy. The purpose of this study is to find out how the development of breast cancer chemotherapy treatment. As for the research method, this research uses literature review, in the search for literature sourced from 2 databases (Pubmed and Google Scholar) using keywords according to the theme. Where the results obtained show that chemotherapy treatment for breast cancer has developed where it has been found that monoclonal antibody therapy and gene therapy have been proven to increase disease-free expectations in breast cancer patients.
LITERATURE REVIEW : Uji Molekular Docking Senyawa Osimertinib Beserta Turunannya Terhadap Reseptor Tirosin kinase Pada kanker Paru- Paru Yuliana, Dewi; Aminah, Aminah; Ishak, Andi Khuswatun Khazanah
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.134

Abstract

Lung cancer is all malignancy in the lung, including malignancy originating from the lung itself (primary). In clinical terms, what is meant by primary lung cancer is a malignant tumor originating from the bronchial epithelium. Current anti-lung cancer therapy has the goal of inhibiting the activity of EGFR. One of the substances that inhibits the action of EGFR is Tyrosine Kinase Inhibitor (TKI). Osimertinib has the potential to inhibit the phosphorylation of cells containing EGFR mutations. This review article aims to determine the ability of osimertinib compounds and their derivatives as lung cancer therapeutic agents against tyrosine kinase receptors using the molecular docking method. The research method used is literature review using two databases, namely Pubmed and Google Scholar for the last 10 years from 2013-2023. And the results obtained are that Osimertinib can be used as a lung cancer therapeutic agent against tyrosine kinase receptors
STUDI PENEGTAHUAN MASYARAKAT TENTANG PENGGUNAAN ANTIBIOTIK DIDESA MANAKKU,KECAMATAN LABAKKANG KABUPATEN PANGKAJENE DAN KEPULAUAN ramadhani, novita annur; Putra, Bayu; Yuliana, Dewi
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.145

Abstract

Antibiotika adalah obat untuk mencegah dan mengobati infeksi yang disebabkan oleh bakteri, penggunaannya yang tidak tepat selain menjadi pemborosan secara ekonomi juga berbahaya secara klinik, yaitu menyebabkan resistensi bakteri terhadap antibiotik. Penelitian ini dilakukan dengan tujuan untuk mengetahui bagaimana pengetahuan masyarakat di Desa Manakku tentang penggunaan antibiotik Responden yang digunakan oleh peneliti yaitu masyarakat yang berdomisili di desa manakku kecamatan labakkang kabupaten pangkajene dan kepulauan dengan proyeksi jumlah penduduk 1.400 jiwa. Setelah di kategorikan berdasarkan dengan kriteria inklusi dan ekslusi sehingga diperoleh data akhir untuk responden yang memenuhi kriteria tersebut yaitu 71 responden. Berdasarkan hasil tersebut tingkat pengetahuan masyarakat tentang penggunaan antibiotik di Desa Manakku sebagian besar responden yaitu 32 responden dengan (45,0%) memiliki pengetahuan cukup. Angka ini menunjukkan bahwa tingkat pengetahun responden tersebut masuk tergolong cukup.
Literatur Review : Studi Penggunaan Antibiotik Terhadap Pasien Ulkus Diabetikum Yuliana, Dewi; Hasmi, Nur; Lolo, Andi Maulana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.184

Abstract

Diabetic ulcers are open wounds on the surface of the skin due to macroangiopathy complications resulting in vascular insufficiency and neuropathy, and can develop into infections due to the entry of germs or bacteria and the presence of high blood sugar which is a strategic place for the growth of germs so that an amputation can occur if blood sugar is too low. the higher it is. The purpose of this study is to find out how the development of treatment using antibiotics for diabetic ulcer disease. The research method is that this study uses literature reviews, in searching literature sourced from 2 databases (Pubmed and Google Scholar) using keywords according to the theme. In contrast to previous studies, this study focuses on the development of treatment using antibiotics in the latest diabetic ulcer patients. The amount of literature used is 13 journal articles. Where the results showed that conservative treatment such as long-term oral and parenteral antibiotics proved effective in patients with diabetic foot ulcers, negative pressure wound therapy methods, Moist Wound Healing, silver type antimicrobials (ActicoatTM), dressings have proven effective in patients.
Literature Review : Studi Rasionalitas Penggunaan Obat Antidibetes Pada Penyakit Diabetes Melitus Tipe 2 Yang Mengalami Komplikasi Nefropati Yuliana, Dewi; Athifah, Athifah
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.185

Abstract

Diabetes melitus merupakan penyakit yang ditandai dengan peningkatan kadar glukosa dalam darah atau melebihi batas normal. Pada penyakit diabetes melitus yang tidak terkontrol akan menyebabkan terjadinya berbagai komplikasi kronik pada pasien diabetes salah satunya yaitu nefropati diabetik. Tujuan penelitian ini yaitu untuk mengetahui rasionalistas penggunaan obat antidiabetes pada penyakit nefropati diabetik. Adapun metode penelitian yaitu penelitian ini menggunakan literature review, dalam pencarian literatur bersumber dari 2 database (Pubmed dan Google Scholar) menggunakan kata kunci sesuai dengan tema. Berbeda dengan penelitian sebelumnya, pada penelitian ini berfokus pada penggunaan obat antidiabetes pada penyakit nefropati diabetik. Adapun jumlah literatur yang digunakan yaitu sebanyak 3 artikel jurnal. Dimana hasil yang didapatkan bahwa penggunaan obat antidibetes pada penyakit nefropati diabetik yang paling efektif yaitu kombinasi antara AOD dengan insulin seperti obat antidiabetes metformin dengan insulin insulin long-acting (kerja panjang) atau atau rapid-acting (kerja cepat).
LITERATURE REVIEW: PENGGUNAAN OBAT ANTIBIOTIK PADA PASIEN PNEUMONIA Yuliana, Dewi; A, Miftahul Janna
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.201

Abstract

Pneumonia is an acute inflammatory disease of the lung parenchyma which usually results from an acute lower respiratory tract infection with coughing and shortness of breath. The purpose of this study was to find out how to use antibiotics in pneumonia patients. The research method is that this study uses literature reviews, in searching literature sourced from 2 databases (Pubmed and Google Scholar) using keywords according to the theme. Unlike previous studies, this study focuses on the use of antibiotic drugs in pneumonia patients. The amount of literature used is 13 journal articles
Co-Authors A, Miftahul Janna Abdul Rasyid, Faradiba afrianti, novi AGUS WIDODO Agus, Asfira Alfirah Angraeni Amalia Amalia Aminah Aminah Ana, Ria Fajrin Rizqi Andi Emelda Andi Maghfirah Nurul Fitri Andi Maulana Kamri Andi Miftahul Jannah Andi Muflihunna Andi Nurul Zakyah .P Ang, Dynasti Kelani ANGIN, MARTIANUS PERANGIN Angriani, Yuni Ariani, Luysi Arifin, Sukmawati Asni Amin Asri, Fitriani Asriani Suhaenah Asrvio Asrvio Aswar, Jumalia Athifah Athifah, Athifah Aulia Fikriyani Hamka Aulia Wati Azizah, Rizqi Azka, Vaza Deefath Az Bayu Putra, Bayu Besse Yulismayanti Damayanti, Alfina Dema Yulianto Dian Anugrah Hasbullah Dzakiyah, Ainun Erfiani, Mia Erwin Putera Permana Eveline Alfara Felia Fairuz Dyah Widowati Faradiba Faradiba Fhara Dilla, Arie Firzan Nainu Fitri Anita, Fitri Fitri, Nurul Gina Feby Syalvi Gulo, Rezeki Putra Haisy, Meilika Handayani, Dian Pratiwi Hasmi, Nur Hasnaeni Hasnaeni Idawati Idawati, Ira Asmaliani Irwan, Andi Annisa Anastasya Ishak, Andi Khuswatun Khazanah Khalid, Davi Rahmat Kholis, Moh. Nur Kholis, Mohammad Nur Lestari Novianti Lia Herliana Lisa Fitriani Listyo Yuwanto Manurung, Maya Mariani, Dini Marwah Marwah Meher, Cashtri Muammar Fawwaz Muhammad Asri Mujtahid, Izzatul Fikri Muliyah, Evi Musdalifah Musdalifah Muslim, Bagus Naniek Widyaningrum Nela, Ari Sukma Nilamsari, Putri Nofita, Nofita Nora Yuniar Setyaputri Novian, Andreas Andri Nur Aisyah Nur Azizah, Rizqi Nur Qadria Nurmaya Effendi Nurmiati Gusfiana Nyoman, Ni Nyoman Sukmawati Oktasari, Masita Oktavia, Santi Paduai, Muh. Harry Bagas Setiawan R. Pamungkas, Bima Kukuh Dwi Poyizar, Poyizar Pratama, Adetia Prayoga, Dwi Fany Priyanti, Iqma Purnamasari, Vina Puspita H, Richta Puspita, Richta Puspitasari, Vimala Putri Veliya Utami Putri, Nurlaila Rachmat Kosman Rahmawati, Rahmawati Ramadhan, Aditya Sukma Ramadhan, Muhammad Fikry ramadhani, novita annur Rezki Amriati Syarif, Rezki Amriati Risda Waris, Risda Rosuliana, Novi Enis Rumintjap, Friedrich M Rusminarni, Siti Saidah, Nida Haura Salam, Rika Amalia Sandyna, Muhammad Ivan Sanusih, Dhea Khoiriyah Sari, Nur Atika Selviyani, Selviyani Siti Nurjanah Subiyantoro, Hari Suhesti, Cila sulastri, diah Sulfiani Sulfiani Syahrul, Andi Ahmad Syam, Andi Suci Alfira Syuhada, Anugerah Putri Tadjuddin Naid Tarina, Tarina Tri Kurniawati Ummum, Andi Unus, Riyan Asrul Usmar Usmar Veronica, Veny Vivi Aulia Wahyudi, Ahyar Wandini, Chindy Waode Yumnal Utamil Wulan, Wulan Yuli Lestari Yuliyanti, Gede Zahra, Siti Fatimah Zari, Fidya Nata Zulfiani Zulfiani