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Literature Review : Perkembangan Pengobatan Kemoterapi Kanker Payudara Yuliana, Dewi; Wulan, Wulan
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.133

Abstract

Breast cancer is a condition where cells lose control and normal mechanisms, resulting in abnormal, fast and uncontrolled cell growth that occurs in the breast. Breast cancer is the most feared disease by women. One of the treatments is chemotherapy. The purpose of this study is to find out how the development of breast cancer chemotherapy treatment. As for the research method, this research uses literature review, in the search for literature sourced from 2 databases (Pubmed and Google Scholar) using keywords according to the theme. Where the results obtained show that chemotherapy treatment for breast cancer has developed where it has been found that monoclonal antibody therapy and gene therapy have been proven to increase disease-free expectations in breast cancer patients.
LITERATURE REVIEW : Uji Molekular Docking Senyawa Osimertinib Beserta Turunannya Terhadap Reseptor Tirosin kinase Pada kanker Paru- Paru Yuliana, Dewi; Aminah, Aminah; Ishak, Andi Khuswatun Khazanah
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.134

Abstract

Lung cancer is all malignancy in the lung, including malignancy originating from the lung itself (primary). In clinical terms, what is meant by primary lung cancer is a malignant tumor originating from the bronchial epithelium. Current anti-lung cancer therapy has the goal of inhibiting the activity of EGFR. One of the substances that inhibits the action of EGFR is Tyrosine Kinase Inhibitor (TKI). Osimertinib has the potential to inhibit the phosphorylation of cells containing EGFR mutations. This review article aims to determine the ability of osimertinib compounds and their derivatives as lung cancer therapeutic agents against tyrosine kinase receptors using the molecular docking method. The research method used is literature review using two databases, namely Pubmed and Google Scholar for the last 10 years from 2013-2023. And the results obtained are that Osimertinib can be used as a lung cancer therapeutic agent against tyrosine kinase receptors
STUDI PENEGTAHUAN MASYARAKAT TENTANG PENGGUNAAN ANTIBIOTIK DIDESA MANAKKU,KECAMATAN LABAKKANG KABUPATEN PANGKAJENE DAN KEPULAUAN ramadhani, novita annur; Putra, Bayu; Yuliana, Dewi
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.145

Abstract

Antibiotika adalah obat untuk mencegah dan mengobati infeksi yang disebabkan oleh bakteri, penggunaannya yang tidak tepat selain menjadi pemborosan secara ekonomi juga berbahaya secara klinik, yaitu menyebabkan resistensi bakteri terhadap antibiotik. Penelitian ini dilakukan dengan tujuan untuk mengetahui bagaimana pengetahuan masyarakat di Desa Manakku tentang penggunaan antibiotik Responden yang digunakan oleh peneliti yaitu masyarakat yang berdomisili di desa manakku kecamatan labakkang kabupaten pangkajene dan kepulauan dengan proyeksi jumlah penduduk 1.400 jiwa. Setelah di kategorikan berdasarkan dengan kriteria inklusi dan ekslusi sehingga diperoleh data akhir untuk responden yang memenuhi kriteria tersebut yaitu 71 responden. Berdasarkan hasil tersebut tingkat pengetahuan masyarakat tentang penggunaan antibiotik di Desa Manakku sebagian besar responden yaitu 32 responden dengan (45,0%) memiliki pengetahuan cukup. Angka ini menunjukkan bahwa tingkat pengetahun responden tersebut masuk tergolong cukup.
Literatur Review : Studi Penggunaan Antibiotik Terhadap Pasien Ulkus Diabetikum Yuliana, Dewi; Hasmi, Nur; Lolo, Andi Maulana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.184

Abstract

Diabetic ulcers are open wounds on the surface of the skin due to macroangiopathy complications resulting in vascular insufficiency and neuropathy, and can develop into infections due to the entry of germs or bacteria and the presence of high blood sugar which is a strategic place for the growth of germs so that an amputation can occur if blood sugar is too low. the higher it is. The purpose of this study is to find out how the development of treatment using antibiotics for diabetic ulcer disease. The research method is that this study uses literature reviews, in searching literature sourced from 2 databases (Pubmed and Google Scholar) using keywords according to the theme. In contrast to previous studies, this study focuses on the development of treatment using antibiotics in the latest diabetic ulcer patients. The amount of literature used is 13 journal articles. Where the results showed that conservative treatment such as long-term oral and parenteral antibiotics proved effective in patients with diabetic foot ulcers, negative pressure wound therapy methods, Moist Wound Healing, silver type antimicrobials (ActicoatTM), dressings have proven effective in patients.
Literature Review : Studi Rasionalitas Penggunaan Obat Antidibetes Pada Penyakit Diabetes Melitus Tipe 2 Yang Mengalami Komplikasi Nefropati Yuliana, Dewi; Athifah, Athifah
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.185

Abstract

Diabetes melitus merupakan penyakit yang ditandai dengan peningkatan kadar glukosa dalam darah atau melebihi batas normal. Pada penyakit diabetes melitus yang tidak terkontrol akan menyebabkan terjadinya berbagai komplikasi kronik pada pasien diabetes salah satunya yaitu nefropati diabetik. Tujuan penelitian ini yaitu untuk mengetahui rasionalistas penggunaan obat antidiabetes pada penyakit nefropati diabetik. Adapun metode penelitian yaitu penelitian ini menggunakan literature review, dalam pencarian literatur bersumber dari 2 database (Pubmed dan Google Scholar) menggunakan kata kunci sesuai dengan tema. Berbeda dengan penelitian sebelumnya, pada penelitian ini berfokus pada penggunaan obat antidiabetes pada penyakit nefropati diabetik. Adapun jumlah literatur yang digunakan yaitu sebanyak 3 artikel jurnal. Dimana hasil yang didapatkan bahwa penggunaan obat antidibetes pada penyakit nefropati diabetik yang paling efektif yaitu kombinasi antara AOD dengan insulin seperti obat antidiabetes metformin dengan insulin insulin long-acting (kerja panjang) atau atau rapid-acting (kerja cepat).
LITERATURE REVIEW: PENGGUNAAN OBAT ANTIBIOTIK PADA PASIEN PNEUMONIA Yuliana, Dewi; A, Miftahul Janna
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.201

Abstract

Pneumonia is an acute inflammatory disease of the lung parenchyma which usually results from an acute lower respiratory tract infection with coughing and shortness of breath. The purpose of this study was to find out how to use antibiotics in pneumonia patients. The research method is that this study uses literature reviews, in searching literature sourced from 2 databases (Pubmed and Google Scholar) using keywords according to the theme. Unlike previous studies, this study focuses on the use of antibiotic drugs in pneumonia patients. The amount of literature used is 13 journal articles
POLA PENGGUNAAN ANTIBIOTIK PADA PASIEN TUBERKULOSIS DI PUSKESMAS PEKKAE KABUPATEN BARRU SULAWESI SELATAN PERIODE JANUARI – DESEMBER 2022 Yuliana, Dewi; Putra, Bayu; Syahrul, Andi Ahmad
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.229

Abstract

ANDI AHMAD SYAHRUL, This study aims to determine the pattern of antibiotic use in tuberculosis patients at the Pekkae Health Center, Barru in 2022. The method used is an observation method using a sampling technique, namely total sampling. The results showed that the dominant male patients were 59.1%; aged 45-54 and 55-64 as much as 22.72%. The use of drugs was adjusted to the patient's weight with intensive phase treatment of 3 2KDT tablets which was 50% then 4 4KDT tablets and 4 2KDT tables which were 27.27% then 3 4KDT tablets and 4 2KDT tablets which were 13.63% and 2 4KDT tablets and 2 2KDT tablets as much as 9.1%. The conclusion in this study is that the use and suitability of OAT is based on the TB control guidelines of the Indonesian Ministry of Health in 2016, which was used in 3 patients who had an increase in the number of tablets taken in combination doses and 1 patient there was a decrease in the number of tablets taken in combination doses and the pattern of using drugs with a fixed dose combination containing rifampicin 150 mg, isoniazid 75 mg, pyrazinamide 400mg, ethambutol 275 mg
A LITERATUR REVIEW : AKTIVITAS IMUNOMODULATOR PADA TANAMAN HERBAL Yuliana, Dewi; Handayani, Dian Pratiwi; Purnamasari, Vina
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 4 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i4.230

Abstract

Health problems that often occur in Indonesia are problems related to diseases caused by free radicals. The presence of free radicals can trigger damage to cells and can disrupt the body's immune system. The immune system can be enhanced or suppressed, one way is by administering immunomodulators. Several natural compounds have the ability to increase immune system activity, including flavonoids, curcumin, limonoids, vitamin C, vitamin E and catechins. Phenolic components such as flavonoids and polyphenols can improve the immune system by increasing Interleukin-12 (IL-12) and lymphocyte proliferation. Based on the many health problems that arise in Indonesia due to the presence of free radicals, the aim of the research is to conduct a literature review on the mechanism of action of herbal plants as immunomodulators and the methods used to determine the mechanism of action of natural immunomodulators. The method used to review this article is to carry out an online search process using several search engines such as PubMed, Scopus, ProQuest and Schoolar. Based on reference studies, several herbal plant extracts act as immunomodulators with different activities such as increasing the activity of Immunoglobulin M (IgM), reducing the number of leukocytes, stimulating the body's immunity with flavonoid content and increasing the ability of phagocytosis.
Evaluation of the use of Antihypertensive Drugs in Outpatient Hypertension Patients at the Lasinrang Regional General Hospital, Pinrang Regency in 2023 Yuliana, Dewi; Agus, Asfira; Azizah, Rizqi
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 2 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/fyke8936

Abstract

Hypertension is a complex condition in which blood pressure is permanently above normal. Hypertension is an increase in systolic blood pressure of more than equal to 140 mmHg and diastolic more than equal to 90 mmHg. This study aims to identify how antihypertensive drugs are used in hypertensive patients at the Lasinrang Regional General Hospital, Pinrang Regency. This study is a non-experimental research with a descriptive design taken retrospectively. The sample in this study is all outpatients with a diagnosis of hypertension at the Lasinrang Regional General Hospital in 2023. The sampling technique used is purposive sampling. The sample of this study is medical record data on hypertension patients in 2023 which is adjusted to the inclusion criteria. The results of the study showed that from 83 samples consisting of 50 women and 33 men, all of which met the inclusion and exclusion criteria, and showed a prevalence of age that dominated around 58-65 years (49,40%). In the evaluation of drug use, outpatient hypertension patients at the Lasinrang Regional General Hospital, Pinrang Regency had an indication accuracy of 100%, 100% drug accuracy, and 100% dose accuracy. 
Evaluation of the Use of Anti-Diabetic Drugs in Outpatient Type 2 Diabetes Mellitus Patients at Lasinrang Regional General Hospital, Pinrang Regency in 2023 Nur Azizah, Rizqi; Damayanti, Alfina; Yuliana, Dewi
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 3 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jpns.v1i3.94101

Abstract

Diabetes Mellitus (DM), including a disease in the form of metabolic disorders characterized by impaired insulin secretion, impaired insulin production and insulin sensitivity, causing an increase in blood sugar levels (hyperglycemia). This study aims to determine the use of antidiabetic drugs which include the right drug, the right dose, the right indication and the right frequency of administration in outpatient type II diabetes mellitus patients at Lasinrang Regional General Hospital, Pinrang District in 2023. This study is a non-experimental research with a descriptive design retrospectively. The sample in this study is all outpatients with a diagnosis of type II diabetes mellitus at the Lasinrang Regional General Hospital, Pinrang District in 2023. The sampling technique used is purposive sampling. The sample of this study is medical record data of patients with type II diabetes mellitus in 2023, which is adjusted to the inclusion criteria. The results of the study showed that of 87 samples consisting of 55 women and 32 men, all of which met the inclusion and exclusion criteria, and showed that the prevalence of age was more susceptible to be affected at the age of 46-55 years as many as 40 patients (45.98%). In the analysis of the accuracy of drug use, outpatient type II diabetes mellitus patients at the Lasinrang Regional General Hospital, Pinrang regency in 2023 have an indication accuracy of 100%, 100% drug accuracy, 100% dose accuracy, and 100% accuracy frequency of drug administration.
Co-Authors A, Miftahul Janna afrianti, novi AGUS WIDODO Agus, Asfira Alfirah Angraeni Allania Hanung Putri Sekar Ningrum Amalia Amalia Amatiria, Gustop Aminah Aminah Ana, Ria Fajrin Rizqi Andi Emelda Andi Maghfirah Nurul Fitri Andi Maulana Kamri Andi Miftahul Jannah Andi Nurul Zakyah .P Ang, Dynasti Kelani Anggraini, Nur Afni ANGIN, MARTIANUS PERANGIN Angriani, Yuni Arifin, Sukmawati Asni Amin Asri, Fitriani Asriani Suhaenah Asrvio Asrvio Aswar, Jumalia Athifah Athifah, Athifah Aulia Fikriyani Hamka Aulia Wati Azizah, Rizqi Azka, Vaza Deefath Az Bayu Putra, Bayu Besse Yulismayanti Bilo, Dyulius Thomas Damayanti, Alfina Dema Yulianto Dian Anugrah Hasbullah Dzakiyah, Ainun Erfiani, Mia Erwin Putera Permana Eveline Alfara Felia Fadhillah, Ummul Fairuz Dyah Widowati Faradiba Faradiba Fhara Dilla, Arie Firzan Nainu Fitri Anita, Fitri Fitri, Nurul Gina Feby Syalvi Gulo, Rezeki Putra Haisy, Meilika Handayani, Dian Pratiwi Hasmi, Nur Hasnaeni Hasnaeni Idawati Idawati, Ira Asmaliani Irwan, Andi Annisa Anastasya Ishak, Andi Khuswatun Khazanah Khalid, Davi Rahmat Kholis, Moh. Nur Kholis, Mohammad Nur Lestari Novianti Lia Herliana Lisa Fitriani Listyo Yuwanto Mailoor, Anastacia Jennifer Alexandrina Manurung, Maya Mariani, Dini Marwah Marwah Meher, Cashtri Muammar Fawwaz Muhammad Asri Mujtahid, Izzatul Fikri Muliyah, Evi Musdalifah Musdalifah Muslim, Bagus Naniek Widyaningrum Nela, Ari Sukma Nilamsari, Putri Nofita, Nofita Nora Yuniar Setyaputri Novian, Andreas Andri Nur Aisyah Nur Azizah, Rizqi Nur Qadria Nurmaya Effendi Nurmiati Gusfiana Nyoman, Ni Nyoman Sukmawati Okta, Oktavianus Rangga Oktasari, Masita Oktavia, Santi Paduai, Muh. Harry Bagas Setiawan R. Pamungkas, Bima Kukuh Dwi Pelitawati, Ida Subardiah Poyizar, Poyizar Prayoga, Dwi Fany Priyanti, Iqma Purnamasari, Vina Puspita H, Richta Puspita, Richta Puspitasari, Vimala Putri Veliya Utami Putri, Nurlaila Rachmat Kosman Ramadhan, Aditya Sukma Ramadhan, Muhammad Fikry ramadhani, novita annur Rangga, Okta Risda Waris, Risda Rosuliana, Novi Enis Rumintjap, Friedrich M Rusminarni, Siti Saidah, Nida Haura Salam, Rika Amalia Sandyna, Muhammad Ivan Sanusih, Dhea Khoiriyah Sari, Nur Atika Selviyani, Selviyani Siti Nurjanah Subiyantoro, Hari Suhesti, Cila Sujiah, Sujiah sulastri, diah Sulfiani Sulfiani Syahrul, Andi Ahmad Syam, Andi Suci Alfira Syuhada, Anugerah Putri Tadjuddin Naid Tri Kurniawati Ummum, Andi Unus, Riyan Asrul Usmar Usmar Veronica, Veny Vivi Aulia Wahyudi, Ahyar Wandini, Chindy Waode Yumnal Utamil Wulan, Wulan Yuli Lestari Yuliyanti, Gede Zahra, Siti Fatimah Zari, Fidya Nata Zulfiani Zulfiani