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POLA PENGGUNAAN ANTIBIOTIK PADA PASIEN TUBERKULOSIS DI PUSKESMAS PEKKAE KABUPATEN BARRU SULAWESI SELATAN PERIODE JANUARI – DESEMBER 2022 Yuliana, Dewi; Putra, Bayu; Syahrul, Andi Ahmad
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.229

Abstract

ANDI AHMAD SYAHRUL, This study aims to determine the pattern of antibiotic use in tuberculosis patients at the Pekkae Health Center, Barru in 2022. The method used is an observation method using a sampling technique, namely total sampling. The results showed that the dominant male patients were 59.1%; aged 45-54 and 55-64 as much as 22.72%. The use of drugs was adjusted to the patient's weight with intensive phase treatment of 3 2KDT tablets which was 50% then 4 4KDT tablets and 4 2KDT tables which were 27.27% then 3 4KDT tablets and 4 2KDT tablets which were 13.63% and 2 4KDT tablets and 2 2KDT tablets as much as 9.1%. The conclusion in this study is that the use and suitability of OAT is based on the TB control guidelines of the Indonesian Ministry of Health in 2016, which was used in 3 patients who had an increase in the number of tablets taken in combination doses and 1 patient there was a decrease in the number of tablets taken in combination doses and the pattern of using drugs with a fixed dose combination containing rifampicin 150 mg, isoniazid 75 mg, pyrazinamide 400mg, ethambutol 275 mg
A LITERATUR REVIEW : AKTIVITAS IMUNOMODULATOR PADA TANAMAN HERBAL Yuliana, Dewi; Handayani, Dian Pratiwi; Purnamasari, Vina
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 4 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i4.230

Abstract

Health problems that often occur in Indonesia are problems related to diseases caused by free radicals. The presence of free radicals can trigger damage to cells and can disrupt the body's immune system. The immune system can be enhanced or suppressed, one way is by administering immunomodulators. Several natural compounds have the ability to increase immune system activity, including flavonoids, curcumin, limonoids, vitamin C, vitamin E and catechins. Phenolic components such as flavonoids and polyphenols can improve the immune system by increasing Interleukin-12 (IL-12) and lymphocyte proliferation. Based on the many health problems that arise in Indonesia due to the presence of free radicals, the aim of the research is to conduct a literature review on the mechanism of action of herbal plants as immunomodulators and the methods used to determine the mechanism of action of natural immunomodulators. The method used to review this article is to carry out an online search process using several search engines such as PubMed, Scopus, ProQuest and Schoolar. Based on reference studies, several herbal plant extracts act as immunomodulators with different activities such as increasing the activity of Immunoglobulin M (IgM), reducing the number of leukocytes, stimulating the body's immunity with flavonoid content and increasing the ability of phagocytosis.
Evaluation of the use of Antihypertensive Drugs in Outpatient Hypertension Patients at the Lasinrang Regional General Hospital, Pinrang Regency in 2023 Yuliana, Dewi; Agus, Asfira; Azizah, Rizqi
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 2 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/fyke8936

Abstract

Hypertension is a complex condition in which blood pressure is permanently above normal. Hypertension is an increase in systolic blood pressure of more than equal to 140 mmHg and diastolic more than equal to 90 mmHg. This study aims to identify how antihypertensive drugs are used in hypertensive patients at the Lasinrang Regional General Hospital, Pinrang Regency. This study is a non-experimental research with a descriptive design taken retrospectively. The sample in this study is all outpatients with a diagnosis of hypertension at the Lasinrang Regional General Hospital in 2023. The sampling technique used is purposive sampling. The sample of this study is medical record data on hypertension patients in 2023 which is adjusted to the inclusion criteria. The results of the study showed that from 83 samples consisting of 50 women and 33 men, all of which met the inclusion and exclusion criteria, and showed a prevalence of age that dominated around 58-65 years (49,40%). In the evaluation of drug use, outpatient hypertension patients at the Lasinrang Regional General Hospital, Pinrang Regency had an indication accuracy of 100%, 100% drug accuracy, and 100% dose accuracy. 
Evaluation of the Use of Anti-Diabetic Drugs in Outpatient Type 2 Diabetes Mellitus Patients at Lasinrang Regional General Hospital, Pinrang Regency in 2023 Nur Azizah, Rizqi; Damayanti, Alfina; Yuliana, Dewi
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 3 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jpns.v1i3.94101

Abstract

Diabetes Mellitus (DM), including a disease in the form of metabolic disorders characterized by impaired insulin secretion, impaired insulin production and insulin sensitivity, causing an increase in blood sugar levels (hyperglycemia). This study aims to determine the use of antidiabetic drugs which include the right drug, the right dose, the right indication and the right frequency of administration in outpatient type II diabetes mellitus patients at Lasinrang Regional General Hospital, Pinrang District in 2023. This study is a non-experimental research with a descriptive design retrospectively. The sample in this study is all outpatients with a diagnosis of type II diabetes mellitus at the Lasinrang Regional General Hospital, Pinrang District in 2023. The sampling technique used is purposive sampling. The sample of this study is medical record data of patients with type II diabetes mellitus in 2023, which is adjusted to the inclusion criteria. The results of the study showed that of 87 samples consisting of 55 women and 32 men, all of which met the inclusion and exclusion criteria, and showed that the prevalence of age was more susceptible to be affected at the age of 46-55 years as many as 40 patients (45.98%). In the analysis of the accuracy of drug use, outpatient type II diabetes mellitus patients at the Lasinrang Regional General Hospital, Pinrang regency in 2023 have an indication accuracy of 100%, 100% drug accuracy, 100% dose accuracy, and 100% accuracy frequency of drug administration.
Evaluation of Drug Related Problems of Antihypertensive Drugs in Inpatient Hypertensive Patients at the Latemmamala Regional General Hospital, Soppeng Regency for the January-March 2023 Period Yuliana, Dewi; Salam, Rika Amalia; Arifin, Sukmawati
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 3 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jpns.v1i3.8493

Abstract

Hypertension is an increase in systolic blood pressure of more than 140 mmHg and diastolic blood pressure of more than 90 mmHg in two measurements taken five minutes apart at rest. Problems caused by drug abuse are called DRPs (Drug Related Problems). The occurrence of DRPs is known to have a detrimental effect on patient quality of life, increased mortality and high medical costs. This study aims to determine the incidence of DRPs and the types of DRPs that occur in hypertensive patients at Latemmamala Hospital, Soppeng Regency. This study is a type of non-experimental descriptive research conducted retrospectively using secondary data in medical records where samples were selected using purposive sampling technique. The results showed that of the 78 samples consisting of 42 women (53.85%) and 36 men (46.15%), all of which met the inclusion and exclusion criteria, showed that the age prevalence was more prone to hypertension at the age of 56-75 years as many as 47 patients (60.26%). There were 46 cases out of 43 patients who had the potential to experience DRPs. The most DRPs that occurred were in the case of C1.4 as many as 26 cases (56.52%), then C1.1 as many as 20 cases (43.48%).
Efektivitas Jus Buah Bit, Lemon Dan Madu Terhadap Peningkatan Kadar Hemoglobin Ibu Hamil Dengan Anemia Suhesti, Cila; Yuliana, Dewi
Jurnal Ilmiah Wahana Pendidikan Vol 10 No 6 (2024): Jurnal Ilmiah Wahana Pendidikan
Publisher : Peneliti.net

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.10637784

Abstract

Pengaruh anemia sangat besar pada kualitas sumber daya manusia, anemia pada kehamilan disebut sebagai potential danger to mother and child yang artinya berpotensi membahayakan ibu beserta anak yang dikandung, karena itu anemia sangat perlu perhatian dari berbagai pihak pelayanan kesehatan sebagai garda terdepan. Tujuan dari penelitian ini yaitu untuk mengetahui efektivitas jus buah bit, lemon dan madu terhadap peningkatan kadar hemoglobin pada ibu hamil dengan anemia. Jenis penelitian ini penelitian kuantitatif, menggunakan rancangan quasi eksperimen dengan non equivalent control group design. Populasi pada penelitian ini ibu hamil dengan anemia. Metode penentuan sampel dengan teknik purposive sampling sehingga didapati sampel sebanyak 24 responden. Hasil penelitian menunjukkan rata-rata kadar Hb sesudah diberikan jus buah bit, lemon dan madu pada kelompok intervensi adalah 11,24 g/dL, sedangkan rata-rata kadar Hb pada kelompok kontrol adalah 10,34. Hasil uji statistik menggunakan uji independent sample t test didapatkan p value = 0,000 < α 0,05, dapat disimpulkan bahwa ada perbedaan efektivitas antara kelompok intervensi dengan kelompok kontrol dalam meningkatkan kadar hemoglobin pada ibu hamil dengan anemia di Wilayah Kerja Puskesmas Rawat Jalan Way Halim Bandar Lampung Tahun 2023. Saran diharapkan kepada petugas kesehatan agar dapat mengoptimalkan penyuluhan bahwa konsumsi jus buah bit, lemon dan madu dapat menjadi pilihan lain dalam meningkatan kadar hemoglobin pada ibu hamil dengan anemia.
Sosialisasi Pengolahan Tepung Porang Menjadi Kue Kering pada Kelompok Ibu-Ibu PKK Desa Paddingin Kecamatan Sanrobone Kabupaten Takalar Yuliana, Dewi; Suhaenah, Asriani; Aminah, Aminah; Effendi, Nurmaya; Sandyna, Muhammad Ivan; Mujtahid, Izzatul Fikri
Abdimas Galuh Vol 6, No 1 (2024): Maret 2024
Publisher : Universitas Galuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25157/ag.v6i1.13273

Abstract

Tujuan kegiatan pengabdian kepada masyarakat ini adalah memberikan edukasi dan pelatihan kepada ibu PKK Desa Paddingin Kecamatan Sanrobone Kabupaten Takalar, Propinsi Sulawesi Selatan mengenai pengolahan tepung Porang menjadi produk kue kering yang baik untuk pencegahan anemia dan bernilai ekonomi, sehingga mampu menjadi salah satu solusi yang tepat dalam peningkatan taraf hidup Masyarakat mitra. Manifestasi kegiatan ini sebagai upaya melakukan transfer ilmu pengetahuan dan teknologi, maupun keterampilan dari kami pihak dunia akademis kepada mitra. Masyarakat mitra diberikan penyuluhan tentang manfaat tepung porang di bidang dan pelatihan teknik membuat kue kering “chocochip” dari tepung porang.  Berdasarkan hasil evaluasi dari 10 anggota mitra yang mengikuti kegiatan tersebut terlihat adanya peningkatan pengetahuan dan wawasan masyarakat tentang potensi tepung porang dan pengolahannya.
Comparative Antioxidant Capacity of Seed and Fruit Ethanol Extracts of Bitter Melon (Momordica charantia L.) Using FRAP Assay Ariani, Luysi; Rasyid, Faradiba Abdul; Yuliana, Dewi; Rahmawati, Rahmawati; Muflihunna, Andi; Amin, Asni; Syarif, Rezki Amriati
Journal of Experimental and Clinical Pharmacy (JECP) Vol 6, No 1 (2026): February 2026
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v6i1.1628

Abstract

Momordica charantia L. (bitter melon) is traditionally consumed as both food and medicine in Indonesia. Its fruit and seeds contain bioactive compounds such as saponins, flavonoids, polyphenols, and unsaturated fatty acids with recognized antioxidant potential. This study compared the antioxidant activity of ethanol extracts from bitter melon seeds and fruit using the Ferric Reducing Antioxidant Power (FRAP) assay. Extraction was conducted by ultrasound-assisted extraction (UAE) with ethanol as solvent, and antioxidant activity was expressed as quercetin equivalents (mg QE/g extract). The seed extract showed an antioxidant value of 8.680 mg QE/g, while the fruit extract exhibited 8.626 mg QE/g. The statistical analysis showed that the p-value was greater than 0.05, indicating no significant difference between the two extracts. This suggests that both extracts exhibit comparable antioxidant activity. These results highlight that both seeds and fruit of M. charantia may serve as promising natural antioxidant sources for functional food and pharmaceutical applications.
Effect of Crushed Binahong (Anredera cordifolia) Leaves on Oral Health Among Pregnant Women Pratama, Adetia; Yuliana, Dewi; Oktavia, Santi
Genius Journal Vol. 7 No. 2 (2026): GENIUS JOURNAL
Publisher : Inspirasi Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/gj.v7i2.1070

Abstract

Introduction: Pregnancy is a common event in a woman's life. It is a physiological state accompanied by hormonal changes, which affect not only general health but also dental and oral health. A pre-survey conducted by researchers on October 14, 2025, of five pregnant women revealed that two reported using binahong leaves as a mouthwash in addition to using toothpaste to brush their teeth. Three had never used binahong as a mouthwash. Objective: The purpose of this study is the effect of boiled binahong leaves (Anredera cardifolia) on maintaining oral health in pregnant women at the Usmalanah Saddam Tanjung Senang Health Center in Bandar Lampung in 2025. Method: This research was conducted from December 18-24, 2025, at the Usmalanah Saddam Tanjung Senang Health Center in Bandar Lampung. The population consisted of 30 pregnant women. The total sampling method was used, resulting in a total sample of 30 respondents. Data collection used a salivary pH observation sheet. The statistical test used was the dependent t-test. Result Based on the data analysis, the α value was 0.000. α value <0.05. This means that boiled binahong leaves (Anredera cardifolia) have an effect on maintaining oral health in pregnant women at the Usmalanah Saddam Tanjung Senang Health Center in Bandar Lampung in 2025. Conclusion: Therefore, planting binahong leaves at home is recommended, as they are very beneficial for health, especially in maintaining personal hygiene.
Effectiveness of the SIGER-U Pocket Book (Seru Toothbrush) in Improving Toothbrushing Skills Among Kindergarten Children Tarina, Tarina; Oktavia, Santi; Yuliana, Dewi
Genius Journal Vol. 7 No. 2 (2026): GENIUS JOURNAL
Publisher : Inspirasi Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Objective: Dental and oral health problems in preschool-aged children still occur frequently, one of which is caused by poor teeth brushing skills. Preschool-aged children are not yet able to maintain oral hygiene independently, so they are at risk of experiencing dental caries. Promotive and preventive efforts are needed through health education using media that suits the characteristics of children. The Siger-U Pocket Book (Fun Toothbrush) is a dental health education medium that is prepared in a simple, visual and interesting way to help children understand and practice the correct way to brush their teeth. This study aims to determine the effect of using the Siger-U Pocket Book (Fun Toothbrush) on improving toothbrushing skills in Citra Melati Kedaton Kindergarten children in Bandar Lampung. Method: This research uses quantitative methods with a pre-experimental design using a one group pretest–posttest design. The research was carried out from 13 December 2025 to 05 January 2026 at Citra Melati Kindergarten in Bandar Lampung. The research population was all 38 Citra Melati Kindergarten children, with a sample of 38 children using a total sampling technique. The research instrument is a toothbrushing skill observation sheet with eight assessment steps. Data analysis was carried out using the Wilcoxon Signed Rank Test after carrying out the Shapiro–Wilk normality test with a significance level of 5%. Result The results of the study showed that there was an increase in children's tooth brushing skills after being given the Siger-U Pocket Book intervention. The Wilcoxon test results show a p-value of 0.000 (p ≤ 0.05), which means that there is a significant effect of using the Siger-U Pocket Book on improving teeth brushing skills. Conclusion: The conclusion of this research is that the Siger-U Pocket Book has a significant effect on improving the toothbrushing skills of preschool children. It is recommended that the Siger-U Pocket Book be used as a medium for dental health education in kindergartens and in dental and oral health promotion activities.
Co-Authors A, Miftahul Janna Abdul Rasyid, Faradiba afrianti, novi AGUS WIDODO Agus, Asfira Alfirah Angraeni Amalia Amalia Aminah Aminah Ana, Ria Fajrin Rizqi Andi Emelda Andi Maghfirah Nurul Fitri Andi Maulana Kamri Andi Miftahul Jannah Andi Muflihunna Andi Nurul Zakyah .P Ang, Dynasti Kelani ANGIN, MARTIANUS PERANGIN Angriani, Yuni Ariani, Luysi Arifin, Sukmawati Asni Amin Asri, Fitriani Asriani Suhaenah Asrvio Asrvio Aswar, Jumalia Athifah Athifah, Athifah Aulia Fikriyani Hamka Aulia Wati Azizah, Rizqi Azka, Vaza Deefath Az Bayu Putra, Bayu Besse Yulismayanti Damayanti, Alfina Dema Yulianto Dian Anugrah Hasbullah Dzakiyah, Ainun Erfiani, Mia Erwin Putera Permana Eveline Alfara Felia Fairuz Dyah Widowati Faradiba Faradiba Fhara Dilla, Arie Firzan Nainu Fitri Anita, Fitri Fitri, Nurul Gina Feby Syalvi Gulo, Rezeki Putra Haisy, Meilika Handayani, Dian Pratiwi Hasmi, Nur Hasnaeni Hasnaeni Idawati Idawati, Ira Asmaliani Irwan, Andi Annisa Anastasya Ishak, Andi Khuswatun Khazanah Khalid, Davi Rahmat Kholis, Moh. Nur Kholis, Mohammad Nur Lestari Novianti Lia Herliana Lisa Fitriani Listyo Yuwanto Manurung, Maya Mariani, Dini Marwah Marwah Meher, Cashtri Muammar Fawwaz Muhammad Asri Mujtahid, Izzatul Fikri Muliyah, Evi Musdalifah Musdalifah Muslim, Bagus Naniek Widyaningrum Nela, Ari Sukma Nilamsari, Putri Nofita, Nofita Nora Yuniar Setyaputri Novian, Andreas Andri Nur Aisyah Nur Azizah, Rizqi Nur Qadria Nurmaya Effendi Nurmiati Gusfiana Nyoman, Ni Nyoman Sukmawati Oktasari, Masita Oktavia, Santi Paduai, Muh. Harry Bagas Setiawan R. Pamungkas, Bima Kukuh Dwi Poyizar, Poyizar Pratama, Adetia Prayoga, Dwi Fany Priyanti, Iqma Purnamasari, Vina Puspita H, Richta Puspita, Richta Puspitasari, Vimala Putri Veliya Utami Putri, Nurlaila Rachmat Kosman Rahmawati, Rahmawati Ramadhan, Aditya Sukma Ramadhan, Muhammad Fikry ramadhani, novita annur Rezki Amriati Syarif, Rezki Amriati Risda Waris, Risda Rosuliana, Novi Enis Rumintjap, Friedrich M Rusminarni, Siti Saidah, Nida Haura Salam, Rika Amalia Sandyna, Muhammad Ivan Sanusih, Dhea Khoiriyah Sari, Nur Atika Selviyani, Selviyani Siti Nurjanah Subiyantoro, Hari Suhesti, Cila sulastri, diah Sulfiani Sulfiani Syahrul, Andi Ahmad Syam, Andi Suci Alfira Syuhada, Anugerah Putri Tadjuddin Naid Tarina, Tarina Tri Kurniawati Ummum, Andi Unus, Riyan Asrul Usmar Usmar Veronica, Veny Vivi Aulia Wahyudi, Ahyar Wandini, Chindy Waode Yumnal Utamil Wulan, Wulan Yuli Lestari Yuliyanti, Gede Zahra, Siti Fatimah Zari, Fidya Nata Zulfiani Zulfiani