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All Journal Jurnal Vokasi Indonesia Darmabakti Cendekia: Journal of Community Service and Engagements Jurnal Layanan Masyarakat (Journal of Public Service) Journal of Parasite Science Ovozoa: Journal of Animal Reproduction Journal of Applied Veterinary Science and Technology IGKOJEI: Jurnal Pengabdian Masyarakat Jurnal ABM Mengabdi journal of Basic Medical Veterinary Journal of Multidisciplinary Applied Natural Science AGRIEKSTENSIA Jurnal Vokasi Indonesia
Gandul Atik Yuliani
Universitas Airlangga
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Veterinary Other

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The Potential of Moringa Leaf Nanoparticles (Moringa oleifera) on the Expression of TNFα, IL10, and HSP 27 in Oral Cavity Cancer Theresia Indah Budhy; Deddy Adam; Zulikran Moh Rizki Azis; Vania Syahputri; M Gandul Atik Yuliani; Muhammad Febriano Sugiarso Suwarto; Fery Setiawan
Journal of Multidisciplinary Applied Natural Science Vol. 4 No. 1 (2024): Journal of Multidisciplinary Applied Natural Science
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.198

Abstract

Oral cancer is currently the sixth leading malignancy in the world, with over 330,000 cases resulting in death. Several cytokines and proteins protect the survival of cancer cells, such as TNF-α, HSP27, and IL-10. Moringa oleifera is an herbal medicine with anti-cancer properties. Nanoparticles of M. oleifera have the property to be easily absorbed by water-soluble cells, so only small doses are needed to be used as anti-cancer ingredients. This research aims to prove the ability of M. oleifera nanoparticle extract against oral cancer through the expression of tumour necrosis factor α (TNF-α), heat shock protein (HSP27), and interleukin 10 (IL-10). Rat as non-human experimental subjects were divided into four groups: control group (K), treatment group 1 (P1), treatment group 2 (P2), and treatment group 3 (P3). Cancer induction was carried out by injecting with benzo[a]pyrene, and then M. oleifera nanoparticle extract was administered in three forms of treatment doses of 125 μg/mL (P1), 250 μg/mL (P2), and 500 μg/mL (P3). Immunohistochemical examination was analysed through TNF-α, HSP27, and IL-10’s expression. The expression of TNF-α and HSP27 between control and treatment groups was significantly different. P2 had the lowest expression of TNF-α and HSP27. The expression of IL-10 between control and treatment groups was also significantly different. P1 had the lowest expression of IL-10. M. oleifera nanoparticle extract can reduce oral cancer progression by decreasing the expression of TNF-α, HSP27, and IL-10.
EMPOWERMENT OF DAIRY CATTLE FARMERS IN THE AREAS SELINGKAR WILIS THROUGH COMMUNITY SERVICE’S POSTGRADUATE SCHOOL: PEMBERDAYAAN PETERNAK SAPI PERAH DI SELINGKAR WILIS, PENGABDIAN KEPADA MASYARAKAT SEKOLAH PASCASARJANA Yuliani, M. Gandul Atik; Madyawati, Sri Pantja; Hariyono, Hariyono
Darmabakti Cendekia: Journal of Community Service and Engagements Vol. 7 No. 1 (2025): JUNE 2025
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/dc.V7.I1.2025.105-110

Abstract

Background: The Postgraduate School strives to establish itself as a world-class institution with a significant global impact. To achieve this vision, it has forged partnerships with regional leaders, emphasizing community service. Our latest initiative, "Community Empowerment of Dairy Cattle Breeders in Selingkar Wilis, Trenggalek Regency," aligns with the Sustainable Development Goals (SDGs). Objective: This initiative aims to empower the community in the Wilis region by providing training in dairy cattle reproduction and production. Method: The program is implemented in two key stages: (1) Offering guidance and training to dairy farmers, and (2) Monitoring and evaluating the outcomes. We measure knowledge gains through assessments conducted before and after the training sessions. Results: Evaluations indicated a significant improvement in dairy farmers' understanding of reproductive health management and the control of Foot and Mouth Disease in their cattle. Conclusion: This initiative has successfully enhanced the skills of breeders in the Wilis area, equipping them to address reproductive issues and manage Foot and Mouth Disease, thereby supporting the agricultural community in Trenggalek Regency.
Factors associated with repeat breeding in Holstein Friesian cows at the Tani Wilis Village Cooperative Unit, Sendang District, Tulungagung Regency, Indonesia Dimas Kunto Satrio; M’ Izi Kumala Lazuardi Sultoni; Tasya Apritalia Putri; Soeharsono Soeharsono; Dadik Rahardjo; Djoko Legowo; Gandul Atik Yuliani; Iwan Sahrial Hamid; Mohammad Anam Al-Arif; Sunaryo Hadi Warsito; Pudji Srianto; Sri Pantja Madyawati; Tita Damayanti Lestari; Wurlina Wurlina
Ovozoa: Journal of Animal Reproduction Vol. 14 No. 2 (2025): Ovozoa: Journal of Animal Reproduction
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ovz.v14i2.2025.67-75

Abstract

This study aimed to evaluate the association of factors such as nutrition, thermal humidity index (THI), age, and lactation period with the occurrence of repeat breeding of dairy cows. The sample consisted of Holstein Friesian cows aged 1-11 years, with lactation periods ranging from 1 to 7 months, currently in lactation, and experiencing repeat breeding (inseminated three or more times without conception, despite exhibiting normal estrous cycles and intervals). The results showed that feeding practices by farmers did not significantly differ (p >0.05) in relation to the incidence of repeat breeding. THI values recorded in several barns also showed no significant differences (p >0.05), with the cows experiencing light to moderate heat stress. Similarly, the frequency of artificial insemination and the estrous cycle intervals remained within the normal range. The highest incidence of repeat breeding was observed in cows aged 2.5 to 5.5 years, accounting for 78.13%, and during lactation periods of 1-3 months, accounting for 81.26%. It can be concluded that there were no significant differences in the provision of forage and leguminous feed between normal cows and those with repeat breeding, and the crude protein content of forage did not influence its occurrence. Additionally, there was no indirect relationship between THI and repeat breeding. However, the incidence of repeat breeding tended to increase in cows aged 3-4 years, and during the second and third lactation periods.
Program penggemukan ternak sapi potong dan pembentukan kelompok ternak armadadi Kawasan Ekonomi Khusus Mandalika Kabupaten Lombok Tengah Nusa Tenggara Barat: Beef Cattle Fattening Program and Establishment of Fleet Cattle Groups in Mandalika Special Economic Zone, Lombok Tengah Regency Nusa Tenggara Barat Yuliani, M. Gandul Atik; Ma'ruf, Anwar; Yuliawan, Rahmat; Rochmi, Siti Eliana
IGKOJEI: Jurnal Pengabdian Masyarakat Vol. 5 No. 3 (2024): IGKOJEI: Jurnal Pengabdian Masyarakat
Publisher : Fakultas Peternakan Universitas Papua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46549/igkojei.v5i3.438

Abstract

ABSTRACT  The Mandalika Special Economic Zone, located in Central Lombok district, West Nusa Tenggara province, is expected to accelerate the tourism sector on the island of Lombok. The Mandalika KEK has potential and advantages that can be developed into an environmentally friendly tourism area. Tourist objects and tourist attractions are expected to always be oriented towards preserving environmental values ​​and quality in society. This increase in the tourism sector will be followed by an increase in the food sector and beef cattle farming is one of them. This Community Service Activity was carried out on Sunday 13 August 2023 at the Reading Corner room managed by Karang Taruna, Pujut District, Central Lombok Regency, West Nusa Tenggara Regency. Approximately 50 breeders around the location attended. This meeting also formed a Breeders Community called "ARMADA" which is an abbreviation of Airlangga-Mandalika, through this community the Community Service team will also provide sustainable guidance to beef cattle breeders. This technology transfer is also realized by the application of giving Dodol Temulawak which is able to increase the level of productivity of beef cattle because it has several benefits, apart from being able to eradicate worms, it can also increase the immune system of beef cattle. Based on the results of the implementation and the enthusiasm of the target community, it can be concluded that the implementation of the activity was able to increase the knowledge and skills of breeders in terms of handling disease cases and the use of Dodol Temulawak in the Mandalika Special Economic Zone area.  Keywords: Beef cattle; Curcuma; Mandalika; Youth organization   ABSTRAK Kawasan Ekonomi Khusus Mandalika terletak di kabupaten Lombok Tengah propinsi Nusa Tenggara Barat diharapkan dapat mengakselerasi sector Pariwisata di pulau Lombok. KEK Mandalika mempunyai potensi dan keunggulan yang bias dikembangkan menjadi daerah pariwisata yang berwawasan lingkungan. Obyek-obyek wisata dan daya tarik wisata diharapkan selalu berorientasi pada kelestarian nilai dan kualitas lingkungan hidup yang ada di masyarakat. Peningkatan sektor pariwisata ini akan diikuti dengan peningkatan sector pangan dan Peternakan sapi potong adalah salah satunya.  Kegiatan Pengabdian Kepada Masyarakat ini telaah dilaksanakan pada hari Minggu tanggal 13 Agustus 2023 bertempat di ruang Pojok Baca yang dikelola Karang Taruna Kecamatan Pujut Kabupaten Lombok Tengah Kabupaten Nusa Tenggara Barat. Dihadiri kurang lebih 50 peternak disekitar lokasi. Pertemuan ini juga membentuk suatu Komunitas Peternak yang dinamakan “ARMADA” yang merupakan singkatan dari Airlangga-Mandalika, melalui komunitas ini tim Pengabdian Kepada Masyarakat juga akan melakukan pembinaan kepada para peternak sapi potong secara sustainable. Alih teknologi ini, juga diwujudkan dengan aplikasi pemberian Dodol Temulawak yang mampu  memacu tingkat produktivitas  sapi potong karena mempunyai beberapa khasiat selain mampu memberantas cacing juga bisa untuk meningkatkan kekebalan tubuh sapi potong. Berdasarkan hasil pelaksanaan dan antusiasme masyarakat sasaran dapat disimpulkan Pelaksanaan Kegiatan  mampu meningkatkan pengetahuan dan ketrampilan peternak dalam hal penanganan kasus-kasus penyakit dan pemanfaatkan dodol Temulawak di wilayah Kawasan Ekonomi Khusus Mandalika. Kata kunci: Karang taruna; Mandalika; Sapi potong; Temulawak
Total protein, albumin, and globulin levels of blood serum in repeat breeder Holstein Friesian cows Asrar, Siti Iqmallisa Nurrill; Rimayanti Rimayanti; Ismudiono Ismudiono; Maslichah Mafruchati; Gandul Atik Yuliani; Ginta Riady
Ovozoa: Journal of Animal Reproduction Vol. 12 No. 2 (2023): Ovozoa: Journal of Animal Reproduction
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ovz.v12i2.2023.90-98

Abstract

This study aimed to determine the relationship between total protein, albumin, and globulin in the blood with the incidence of repeat breeders in dairy cows. Ten normal cyclic cows and ten repeat breeders cows were taken randomly based on the reproductive records of the Tani Wilis Village Cooperative, Sendang District, Tulungagung Regency. Questionnaire data in the form of farmers' knowledge about dairy cows' reproductive systems and feed treatment is displayed descriptively.  Dairy cows blood samples were taken from the jugular vein 6 mL to measure total protein, albumin, and globulin levels. Data analyzed using the Statistical Product and Service Solution software at a significance level of 5%. The results showed that the total protein, albumin, and globulin levels in normal dairy cows and dairy cows with repeat breeders were not significantly different (p>0.05). However, in normal cyclic cows, most of the total protein, albumin, and globulin levels (80-100% of normal cyclic cows samples) are within the normal range. Meanwhile, the majority of repeat breeder cows (60-70% of the repeat breeder cows) had total protein, albumin, and globulin levels lower than the normal range (p<0.05). It could be concluded that there was a relationship between the incidence of repeat breeder and total protein, albumin, and globulin levels in the blood serum of dairy cows with repeat breeder. Therefore, it is suggested to raise awareness of smallholder farmers about proper feeding and feeding management to reduce repeat breeder cases.
Deteksi Aeromonas hydrophila pada Ginjal Mencit Mus musculus dengan Teknik Imunohistokimia Intan Galuh Bintari; M Gandul Atik Yuliani
Agriekstensia : Jurnal Penelitian Terapan Bidang Pertanian Vol. 19 No. 2 (2020): AGRIEKSTENSIA: Jurnal Penelitian Terapan Bidang Pertanian
Publisher : Politeknik Pembangunan Pertanian Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (401.719 KB) | DOI: 10.34145/agriekstensia.v19i2.935

Abstract

ABSTRAK Penelitian ini bertujuan untuk mengetahui apakah Aeromonas hydrophila dapat dideteksi dengan menggunakan teknik imunohistokimia. Imunohistokimia adalah suatu proses untuk mendeteksi antigen (protein, karbohidrat, dll.) Terhadap sel jaringan dengan prinsip reaksi antibodi yang berikatan dengan antigen di dalam jaringan. Parameter penelitian ini adalah interaksi antigen dan antibodi yang divisualisasikan dengan munculnya warna coklat pada ginjal yang diinfeksi Aeromonas hydrophila. Mencit (Mus musculus) umur tiga bulan seberat 30 gram diinfeksi Aeromonas hydrophila dengan dosis 106 CFU / ml. Setelah seminggu, ginjal disiapkan untuk preparat histopatologi dengan pewarnaan imunohistokimia. Antibodi primer yang digunakan adalah antibodi kelinci (New zealand white) dengan dua perlakuan (P1 dan P2). P1 diinfeksi dengan menggunakan protein spesifik Aeromonas hydrophila 30 kDa dan P2 diinfeksi dengan menggunakan protein utuh Aeromonas hydrophila. Hasilnya ditunjukkan dengan membandingkan P1 dan P2. Hasil penelitian menunjukkan bahwa terdapat perbedaan warna coklat yang lebih banyak melalui P2 dibandingkan dengan P1. Kata kunci—Aeromonas hydrophila, Mencit (Mus musculus), Antigen, Teknik Imunohistokimia. ABSTRACT This research was aimed to determine whether the Aeromonas hydrophila can be detected by using immunohistochemistry technique. Immunohistochemistry was a process to detect antigens (proteins, carbohydrates, etc.) towards the cells of the tissues with antibodies reaction principle that binded to antigen in the tissues. The parameter of this research was an interaction between antigens and antibodies which were visualized by the appearance of brown color in the kidneys which were infected by Aeromonas hydrophila. The three-month old mice (Mus musculus) with 30 grams of weight were infected by Aeromonas hydrophila with 106 CFU/ml of doses. After a week, the kidneys were prepared for histopathology preparation by using immunohistochemistry staining. The primary antibodies used were rabbits’ antibodies (New zealand white) with two treatments (P1 and P2). P1 was infected by using spesific proteins of Aeromonas hydrophila 30 kDa and P2 was infected by using the whole proteins of Aeromonas hydrophila. The results were showed by comparing P1 and P2. The results showed that there was a difference in the brown color which was more through in P2 compared to P1. Keywords—Aeromonas hydrophila, Mice (Mus Musculus), Antigens, Immunohistochemistry Technique.
Co-Authors Agung Budianto Achmad, Agung Budianto Agus Widodo Agus Widodo Ahmad Thoriqul Firdaus Aksono HP., Eduardus Bimo Al arif, Mohammad Anam Almira Aurellia Amalia Ristanti Andini Avita Ayu Anggri Septiana Annise Proboningrat Anwar Ma'ruf Anwar Ma'ruf Asrar, Siti Iqmallisa Nurrill Bambang Sumaryono Bimo Aksono Herupradoto Chrismanto, Dony Chusniati, Sri Dadik Rahardjo Daiva Ilyaning Asrin Dalila Fadhila Hidayat Deddy Adam Devi Listiani Dewi Setiyoningsih Dimas Kunto Satrio Diyantoro Diyantoro, Diyantoro Djoko Legowo Dwi Lestari Ega Putri Novitasari Erina Devi Yuniara Sari Ernawati, Rahaju Fansurina Erdayanti Fery Setiawan Ginta Riady Hariyono Hariyono Hidajati, Nove Hidayatik, Nanik intan galuh bintari Ismudiono Ismudiono Iwan Sahrial Hamid Jasmina Vidi Quamilla Kurnia Nisa Kinasih Laeli Amelia Melani Lia Lusanti Lucia Tri Suwanti, Lucia Tri M. Aji Saputro M. Wildan Sulthon Al Fikri Ma'ruf, Anwar Mafruchati, Maslichah Mochammad Yusuf M. Muhammad Febriano Sugiarso Suwarto Muhammad Sururi M’ Izi Kumala Lazuardi Sultoni NASHIHATUS SHOLIHAH Nidia Syafira Nove Hidajati Nunuk Dyah Retno Lastuti Nur Mariam Kusuma Nurrahmad, Nanda Rino Nusdianto Triakoso Oriza Cahya Rahmadiati Poedji Hastutiek Poetranto, Emmanuel Djoko Pricilia Yuniar Sianggi Pudji Srianto Ratna Ayu Ningrum Ratna Damayanti Retno Sri Wahjuni Rimayanti Rimayanti Roby Atul Nazila Adawiyah Rochmi, Siti Eliana Sherbina Bai Soeharsono Soeharsono Sofyan, Miyayu Soneta Sri Hidanah Sri Pantja Madyawati Sri Pantja Madyawati, Sri Pantja ST. Nabilah Mardhiyah Sunarso, Agus Tasya Apritalia Putri Taufik Tri Laksono Theresia Indah Budhy Tita Damayanti Lestari Tri Wahyu Suprayogi Vania Syahputri Vida Brilian Wahjuni, Retno Sri Wahyu Perdana Wahyuni, Retno Sri Wardhana, Dhandy Koesoemo Warsito, Sunaryo Hadi Widjiati Widjiati, Widjiati Widya Paramita Lokapirnasari Wildan Hakam Maulidy Wiranata, Try Ardhi Wiwin Retnowati Wurlina, W Yuliawan, Rahmat Yusril Nur Mahendra Zulikran Moh Rizki Azis