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All Journal Jurnal Kesehatan Masyarakat Andalas (Andalas Journal of Public Health) Jurnal Kesehatan Andalas Sari Pediatri Paediatrica Indonesiana Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Human Care Journal Contagion: Scientific Periodical Journal of Public Health and Coastal Health Indonesian Journal of Electrical Engineering and Computer Science Science Midwifery Indonesian Journal of Global Health research Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal EduHealth Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Ilmu Kesehatan Masyarakat Indonesian Journal of Advanced Research (IJAR) Proceeding International Health Conference Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal) Frontiers on Healthcare Research
Finny Fitry Yani
Universitas Andalas Padang
Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Journal : Paediatrica Indonesiana

 1 
Procalcitonin for detecting community-acquired bacterial pneumonia Devi Gusmaiyanto; Finny Fitry Yani; Efrida Efrida; Rizanda Machmud
Paediatrica Indonesiana Vol 55 No 2 (2015): March 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.416 KB) | DOI: 10.14238/pi55.2.2015.65-69

Abstract

Background Pneumonia is a major cause of morbidity andmortality in children under five years of age. Pneumonia can be ofbacterial or viral origin. It is difficult to distinguish between thesetwo agents based on clinical manifestations, as well as radiologicaland laboratory examinations. Furthermore, bacterial cultures taketime to incubate and positive results may only be found in 10-30%of bacterial pneumonia cases. Procalcitonin has been used as amarker to distinguish etiologies, as bacterial infections tend toincrease serum procalcitonin levels.Objective To determine the sensitivity, specificity, positivepredictive value and negative predictive value of procalcitoninin community-acquired bacterial pneumonia.Method This cross-sectional study was conducted in thePediatric Health Department of Dr. M. Djamil Hospital, Padang.Subjects were selected by consecutive sampling. Procalcitoninmeasurements and PCR screening were performed on bloodspecimens from 32 pneumonia patients and compared.Results Of the 32 subjects, most were boys (56.25%), under 5years of age (99%), and had poor nutritional status (68.75%).Using a cut-off point of 0.25 ng/mL, procalcitonin level hada sensitivity of 92%, specificity 50%, positive predictive value 88%, and negative predictive value 60% for diagnosing bacterial pneumonia. Using a cut-off point of 0.5 ng/mL, procalcitonin level had a specificity of 46%, specificity 83%, positive predictive value 91%, and negative predictive value 25%.Conclusion A cut-off point of 0.25 ng/mL of procalcitonin level may be more useful to screen for bacterial pneumonia than a cutoff point of 0.5 ng / mL. However, if the 0.25 ng/mL cut-off point is used, careful monitoring will be required for negative results, as up to 40% may actually have bacterial pneumonia. [PaediatrIndones. 2015;55:65-9.].
Bacterial pneumonia score to identify bacterial pneumonia Ied Imilda; Finny Fitry Yani; Didik Hariyanto; Darfioes Basir
Paediatrica Indonesiana Vol 55 No 2 (2015): March 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (98.784 KB) | DOI: 10.14238/pi55.2.2015.79-82

Abstract

Background Pneumonia is caused by either bacterial or viraletiologies, with similar symptoms in children. The bacterialpneumonia score (BPS) is a clinical assessment comprised ofseveral investigations: age, assessment of axillary temperature,absolute neutrophil count, band neutrophil percentage, andinterpretation of radiological examination. The score will use todifferentiate the etiology of pneumonia.Objective To determine the sensitivity, specificity, positivepredictive value, and negative predictive value of BPS inidentifying bacterial pneumonia in children.Methods This diagnostic study was performed at Dr. M. DjamilHospital, Padang, West Sumatera where subjects were selected byconsecutive sampling. Fifty-seven patients were diagnosed withpneumonia. Three patients suffered from ventricular septal defects,8 patients refused to provide blood specimens and 3 patients’chest X-rays could not be interpreted, hence, 43 subjects wereincluded in the study. Chest X-rays were interpreted by a pediatricpulmonology consultant. Leukocyte and differential counts wereperformed by a clinical pathology consultant. Subjects’ BPS scoreswere compared to multiplex PCR examinations of blood specimens,as the gold standard.Result Of 43 subjects, 27 (62.79%) were male. Subjects’ mean age was 29.3 (SD 21.5) months. Twenty (46.51%) subjects had good nutritional status, 4 (9.31%) subjects had axillary temperature ≥39°C, and 22 (51.16%) subjects had absolute neutrophil counts ≥8.000/mm3. Bacterial pneumonia score (BPS) had 69% sensitivity, 60% specificity, 42% positive predictive value, and 81% negative predictive value.Conclusion In this study, BPS has low sensitivity and specificityfor identifying bacterial pneumonia.
Tuberculosis score chart signs and symptoms in children with positive tuberculin skin tests Finny Fitry Yani; Rizanda Machmoed; Marhefdison Marhefdison; Darfioes Basir
Paediatrica Indonesiana Vol 52 No 2 (2012): March 2012
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (120.271 KB) | DOI: 10.14238/pi52.2.2012.78-85

Abstract

Background The Indonesian Pediatrics Respirology WorkingGroup (IPRWG) developed the tuberculosis (TB) scorechart to assist in diagnosing TB in community health centers(Puskesmas).Objectives To document signs and symptoms of the IPRWG TBscore chart, to analyze various combinations of these signs andsymptoms, and to compare these combinations in children withTB to those without TB, based on a TB score chart.Methods We performed a cross-sectional study from July toOctober 2008, in Padang, Bukittinggi and Pasaman. We recruitedchildren with known positive tuberculin skin tests (TST) from a2006 tuberculin survey. Questionnaires on signs and symptoms(IPRWG TB score chart) were completed and chest radiographswere obtained for all children. Subjects fulfilling a total score ofsix or more were considered to have a diagnosis of TB.Results We diagnosed TB in 78/285 (27.3%) subjects. A scorevalue of3 for the category of household contact (HHC) positivesmears was added in 21/78 subjects. However, the highest risk forTB disease was found in those diagnosed with no clear history ofHHC (58.9%; OR 192, 95% CI 22 to 1679). The highest riskfactors for TB were suggestive chest X-ray (34.6%; OR 9.2, 95%CI 3.6 to 23 .4) and fever lasting > 2 weeks (17.9%; OR 8, 95%CI 2.2 to 29.1), respectively. Of 46 children with TB diagnosisbut without HHC, the combination of undernourishment, lymphnode enlargement and suggestive chest X-ray was highest (28.2%).Individual or dual combination signs and symptoms were alsofound in children without TB diagnosis.Conclusion Various combinations of signs and symptoms couldlead to fulfillment of scoring for TB diagnosis. [Paediatr lndones.2012;5 2: 78-85].
Relationship between serum ferritin and zinc levels in patients with major thalassemia Hervita Yeni; Finny Fitry Yani; Amirah Zatil Izzah; Gustina Lubis
Paediatrica Indonesiana Vol 59 No 3 (2019): May 2019
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (244.731 KB) | DOI: 10.14238/pi59.3.2019.144-9

Abstract

Background In thalassemia patients, reduced zinc absorption results from increased serum iron due to repeated blood transfusions, increased iron absorption due to ineffective erythropoiesis, and competitive inhibition between iron and zinc in binding to transferrin, a means of transporting both types of minerals in the blood. Few studies have been done to examine zinc levels in thalassemia patients and its relationship with ferritin. Objective To compare serum zinc in thalassemia patients and healthy controls and to assess for a possible correlation between serum ferritin and zinc in thalassemia patients. Methods This cross-sectional study in 68 subjects was done from October 2016 to August 2017. Serum ferritin measured by chemiluminescence immunoassay and serum zinc by inductively coupled plasma mass spectrometry (ICP-MS). Wilcoxon test was used to analyze for differences between serum zinc in thalassemia patients and controls. Spearman’s correlation test was used to analyze for a possible correlation between ferritin and serum zinc in thalassemia patients. Results There were 34 patients with thalassemia and 34 healthy control subjects. The median serum zinc was 119.34 µg/dL (IQR=71.27) in the thalassemia group and 120.08 µg/dL (IQR=26.28) in the control group (P=0.36). There was no significant correlation between serum ferritin and zinc in thalassemic children (r=-0.023; P=0.895). Conclusion There is no significant difference in serum zinc levels between thalassemic children and healthy controls. There is no significant correlation between serum ferritin and zinc in thalassemic children.
Calcitriol levels and the stage of chronic kidney disease in children Diska Yulia Trisiana; Finny Fitry Yani; Fitrisia Amelin; Aumas Pabuti
Paediatrica Indonesiana Vol 62 No 5 (2022): September 2022
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi62.5.2022.318-23

Abstract

Background Kidney damage in chronic kidney disease (CKD) disrupts the 1?-hydroxylase enzyme, preventing the conversion of vitamin D into the active form of calcitriol. To our knowledge, no previous studies have assessed calcitriol levels in children with CKD. Decreased vitamin D levels may occur at an early stage of the disease, so it is important to evaluate calcitriol levels in children with early stage CKD. Objective To assess calcitriol levels in children with CKD according to disease stage and other characteristics. Methods This cross-sectional study was conducted on 43 pediatric CKD patients at Dr. M Djamil Hospital, Padang, Indonesia. We recorded patient characteristics and performed laboratory tests, including routine hematology, blood urea nitrogen (BUN), creatinine, uric acid, electrolytes, calcium, and calcitriol levels. Based on estimated glomerular filtration rate (GFR), patients were grouped into either early-stage (stages I and II), or advanced-stage (stages III to V) CKD. Univariate and multivariate analyses were conducted to determine the association between calcitriol levels with disease stage and other characteristics. Results The overall mean calcitriol level of our subjects was 108.77 (SD 10.79) pmol/L. Mean levels at each CKD stage from I to V were 164.28 (SD 160.90), 94.14 (SD 50.63), 72.16 (SD 13.18), 62.92 (SD 4.87), and 67.51 (SD 4.87) pmol/L, respectively. Calcitriol levels did not differ significantly by CKD stage (P=0.114) when each stage from I to V was considered separately. There was no significant difference in calcitriol levels by growth characteristics (P=0.944), etiology (P=0.311), or anemic status (P=0.104). However, low calcitriol levels were found in all subjects with advanced stage CKD, compared to 63.6% subjects with early stage CKD (P=0.004). Mean calcitriol levels were significantly lower in CKD stage IV (P=0.049) and stage V (P=0.027) compared to stage I. Conclusions The decrease in calcitriol level occurs at an early stage in CKD. Calcitriol levels are significantly lower in advanced stage than in early stage CKD.
Challenges and opportunities to improve tuberculosis care for Indonesian children Graham, Stephen M.; Dwihardiani, Bintari; Felisia, Felisia; Koesoemadinata, Raspati Cundarani; Putri, Nina Dwi; Alisjahbana, Bachti; Lestari, Trisasi; Yani, Finny Fitry; Triasih, Rina
Paediatrica Indonesiana Vol. 65 No. 1 (2025): January 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.1.2025.1-9

Abstract

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Co-Authors Abi Andayu Adang Bachtiar Adefri Wahyudi Afdal Afdal Afdal Ahmad Junaidi Ahmad Kurniawan Akbar Aidil Rahman Novesar Alfi Maido Alius Alkamdani, Riki Amelin, Fitrisia Amirah Zatil Izzah Andani Eka Putra Ariescha, Putri Ayu Yessy Arni Amir Arwin AP Akib Asrawati Asrawati Aumas Pabuti Aumas Pabuti Bachti Alisjahbana Bambang Supriyatno Beni Indra, Beni Br Ginting Munthe, Novita Chicy WIdya Morfi Chika Aulia Husna Darfioes Basir Darfioes Basir Darfioes Basir Darfioes Basir Darfioes Basir Darfious Basir Darmawan B. Setyanto Dasman, Hardisman Denas Symond Desmawati Destri Linjani Devi Gusmaiyanto Devita, Retno Dhyna Lidya Lestari Diana Nur Asrini Didik Hariyanto Didik Hariyanto Didik Hariyanto Dini Anggini Diska Yulia Trisiana Diska Yulia Trisiana Dita Maharani Dwiana Ocviyanti Dwihardiani, Bintari Dya Mulya Lestari Edison Edison Efrida Efrida Efrida Eka Agustia Rini Elsesmita Elsesmita Emeraldy Chatra Erkadius Erkadius Erli Meichory Viorika Eryati Darwin Fauzar Fauzar Felisia . Firman Arbi Gustina Lubis Gustina Lubis Hafifatul A Rahmy Hafni Bachtiar Hanifa Hanif Hardisman Dasman Harun Harnavi Helmizar Hervita Yeni Hirowati Ali, Hirowati Humaira, Hamdini Husna Yetti Husna Yetti Ied Imilda Ihsan, Indra Ikhsan Marzony Ilmiawati Ilmiawati, Ilmiawati Imil Irsal Imran Indra Ihsan Indrapriyatna, Ahmad Syafruddin Indri Permata Rani Irhamna Yusra Irvan Medison Irvan Medison Irvan Medison Iskandar Fitri, Iskandar Koesoemadinata, Raspati Cundarani Lita Farlina Liza Fitria Liza Fitria, Liza Lydia Aswati, Lydia Machdawaty Masri Masri Marhefdison Marhefdison Muhammad Hendri Munthe, Novita Br Ginting Nastiti Kaswandani Nelwati, Nelwati Nia Kurniati Nice Rachmawati Nina Dwi Putri Nisa Haska Maulina Novi Violona Edwar Nur Afrainin Syah Nur Indrawaty Lipoeto Nurul Noviarisa Osharinanda Monita Rahmi Lestari Rahmi, Yannisa Mutiara Rapida Saragih Ratno Widoyo, Ratno Revi Riliani Ricco Azali Riki Alkamdani Rima Semiarty Rina Triasih Rinang Mariko Rizanda Machmoed Rizanda Machmoed Rizanda Machmud Rizanda Machmud Rizki Meizikri Roni Eka Sahputra Roza Erisma Roza Kurniati Russilawati, Russilawati Sahputra, Roni Eka Sari, Maharani Permata Shinta Ayudhia Stephen M. Graham, Stephen M. Susmiati Susmiati Syahredi SA Trisasi Lestari, Trisasi Triyanto Triyanto Utari Gustiany G Viorika, Erli Meichory Youri, Riana Yuhandri Yuhandri, Yuhandri Yuniar Lestari Yuniar Lestari Yusrawati Yusrawati Yusri Dianne Jurnalis Yusri Dianne Jurnalis Zeffira, Laura Zelly Dia Rofinda