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Pregnancy confirmed COVID-19 in hospital Dr. M. Djamil Padang periode 2020-2021 Aladin Aladin; Linosefa Linosefa; Muhammad Rafky Alfi Putra
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 2 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.2.152-158.2022

Abstract

Introduction: Coronavirus disease 2019 (COVID-19) caused a highly acute respiratory infection and high mortality. Symptoms of COVID-19 would be more severe if it affects people at high risk, one of which is pregnant women. This study aims to determine the characteristics of pregnant women with confirmed COVID-19 at RUSP Dr. M. Djamil Padang Objective: to find out the profile of the maternal charactheristic confirmed COVID-19 in hospital Dr. M. Djamil Padang Periode 2020-2021. Methods: This type of research is descriptive with a total sampling technique using secondary data, namely patient medical records. The sample of this study were all pregnant women who were confirmed to have COVID-19 at RSUP Dr. M. Djamil Padang for the 2020-2021 period with a total sample of 186 patient medical records. Univariate data analysis is presented in the form of frequency distribution and data processing using the Computerized SPSS version of the IBM version 26.0. Results: The highest age group was 20-35 years old (78%), the most addresses were Padang City (43,5). %), the most gravida status was multigravida (71,5%), the most parity status was multipara (38,2%), the most gestational age was third trimester (81,7%), the most clinical symptoms are asymptomatic (44,1 %), and the most comorbid status was without comorbid (82,3%). Conclusion: The most pregnant women have confirmed COVID-19 at RSUP Dr. M. Djamil Padang in 2020-2021 with characteristics of age 20-35 years, address in Padang City, status of multigravida and multiparous pregnancy, third trimester gestational age, asymptomatic and no comorbidities.
Identifikasi Soil Transmitted Helminths (STH) pada Sayur Kubis (Brassica Olerace) yang Dijual Pedagang Makanan di Jalan Adinegoro – Prof. Dr. Hamka, Kota Padang Fathoni Akbar; Selfi Renita Rusjdi; Linosefa Linosefa
ANATOMICA MEDICAL JOURNAL | AMJ Vol 5, No 2 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/amj.v5i2.9315

Abstract

Soil Transmitted Helminths (STH) adalah istilah yang merujuk kepada parasit cacing nematoda usus yang memerlukan tanah untuk menjadi bentuk infektif. Salah satu cara masuk telur ataupun bentuk infektif dari STH kedalam tubuh manusia melalui sayuran mentah yang dikonsumsi secara langsung. Tujuan dari penelitian ini adalah untuk mengetahui kontaminasi telur STH pada sayur kubis (Brassica oleracea) yang dijual oleh pedagang makanan di sepanjang Jalan Adinegoro – Prof. Dr. Hamka Kota Padang. Penelitian ini merupakan penelitian deskripsi observasional dan sampel yang dipilih adalah total sampling disepanjang lokasi penelitian, dan didapatkan sampel sebanyak 30 buah kubis. Pada sampel dilakukan pemeriksaan dengan metode sedimentasi. Hasil pemeriksaan dilihat dengan menggunakan mikroskop. Analisa data menggunakan tabel distribusi frekuensi. Hasil penelitian ini ditemukan satu sampel terkonfirmasi positif oleh cacing tambang pada stadium larva filarifom.Kata Kunci: Soil Transmitted Helminths, kubis, kontaminasi
Perbandingan Pola Kepekaan Antibiotik Bakteri Penghasil Extended Spectrum Beta-Lactamase Penyebab Infeksi Saluran Kemih di Rumah Sakit Umum Pusat Dr. M. Djamil Padang Evita Pratiwi; Linosefa Linosefa; Fitrisia Amelin
Sari Pediatri Vol 25, No 3 (2023)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp25.3.2023.163-9

Abstract

Latar belakang. Infeksi saluran kemih merupakan salah satu penyakit infeksi bakteri yang umum terjadi pada anak. Kultur urin dan uji sensitivitas antibiotik diperlukan sebelum menegakan diagnosis dan terapi.Tujuan. Penelitian ini bertujuan untuk mengetahui perbandingan pola kepekaan antibiotik bakteri penghasil Extended Spectrum Beta-Lactamase dan Non-Extended Spectrum Beta-Lactamase penyebab Infeksi Saluran Kemih pada anak di Rumah Sakit Umum Pusat Dr. M. Djamil Padang tahun 2018 – 2020.Metode. Jenis penelitian yang digunakan adalah analitik observasional dengan desain potong lintang pada uji sensitivitas bakteri penyebab infeksi saluran kemih pada anak menggunakan VITEK®2. Usia, jenis kelamin, penyakit dasar, bakteri, ESBL, dan pola kepekaan telah diteliti. Teknik pengambilan sampel menggunakan teknik simple random sampling dengan jumlah sampel 98 orang.Hasil. Hasil penelitian menemukan kasus ISK anak paling banyak pada anak perempuan. Kelompok usia terbanyak adalah 0 – 1 tahun dengan usia rerata 4,5 tahun (standar deviasi, SD ± 5,8 tahun). Tipe infeksi yang banyak ditemukan adalah infeksi saluran kemih simpleks. Selain itu, juga ditemukan kasus kompleks dengan penyakit terbanyak yang mendasari adalah hidronefrosis. Bakteri yang umum menjadi penyebab adalah Escherichia coli (40,3%) dan Klebsiella pneumoniae (26,88%), dengan prevalensi bakteri penghasil enzim extended spectrum beta-lactamase masing-masing 72,7% dan 67,4%. Terdapat perbedaan yang signifikan antara pola kepekaan bakteri Escherichia coli pada antibiotik ampisilin, aztreonam, seftazidim, siprofloksasin, seftriakson, seftazidim, sefepim, nitrofurantoin, gentamisin, dan trimetoprim/sulfametoksazol. Terdapat perbedaan yang signifikan antara pola kepekaan bakteri Klebsiella pneumonia pada antibiotik aztreonam, siprofloksasin, seftriakson, ertapenem, dan meropenem.Kesimpulan. Penyebab paling umum infeksi saluran kemih pada anak adalah bakteri enterik Gram-negatif dan terdapat penurunan sensitivitas antibiotik pada bakteri penghasil ESBL. 
Hubungan Merokok dan Aktivitas Fisik dengan Kejadian Akne Vulgaris Siti Rahmawati; Satya Wydya Yenny; Linosefa Linosefa
VitaMedica : Jurnal Rumpun Kesehatan Umum Vol. 2 No. 3 (2024): Juli : VitaMedica : Jurnal Rumpun Kesehatan Umum
Publisher : STIKES Columbia Asia Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62027/vitamedica.v2i3.108

Abstract

Background: Acne vulgaris is a chronic inflammation of the pilosebaceous follicle and its causes are multifactorial. Smoking causes changes in skin microcirculation, keratinocytes, fibroblasts and blood vessels. Physical activity can cause acne vulgaris because there is an increase in sweat secretion followed by sebum hypersecretion. Objective: This study aims to determine the relationship between smoking and physical activity with the incidence of acne vulgaris. Methods: This study used a cross-sectional design conducted in December 2021 at the Faculty of Medicine, Unand and the Griya Satya Clinic. The research population was male students of the Faculty of Medicine, Unand batch 2018. The method used total sampling method, there were 61 respondents in the age range of 19-22 years. The data obtained were primary data from a questionnaire and the diagnosis was confirmed by extraction of comedones. The analysis uses the chi-square test to determine the relationship between variables.Results: The results of statistical test using thetest chi-square showed that, there is no significant relationship between smoking habits and the incidence of acne vulgaris (p = 0.335), there is no significant relationship between physical activity habits and the incidence of acne vulgaris (p value = 0.851), there is no relationship significant relationship between smoking habits and physical activity with the incidence of acne (p value = 0.335). Conclusion: Medical students at the Faculty of Medicine, Andalas University, most of them had light smoking habit and most of them had moderate-to-heavy physical activity. And there is no relationship between smoking and physical activity toward the incidence of acne vulgaris.
Antibacterial Activity of Endophytic Bacterial Isolates from Kaempferia galanga Leaves Rafifa Ridha; Dira Hefni; Zetryana Puteri Tachrim; Gian Primahana; Jepri Agung Priyanto; Linosefa Linosefa; Adrial Adrial; Endrinaldi Endrinaldi; Muhammad Eka Prastya
Jurnal Kimia Sains dan Aplikasi Vol 27, No 11 (2024): Volume 27 Issue 11 Year 2024
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.27.11.538-548

Abstract

Indonesia has a high biodiversity, which can be relied upon as a potential source of medicinal materials. One of the medicinal plants in Indonesia is Kaempferia galanga, which demonstrates various pharmacological properties, including antibacterial, anti-inflammatory, antioxidant, anticancer, and antiangiogenic effects. However, directly extracting active compounds from plants requires a considerable amount of biomass. To address this challenge, utilizing endophytic bacteria associated with these plants presents a promising alternative. Consequently, the antibacterial activity of endophytic bacterial isolates from K. galanga leaves needs to be investigated. This study is an experimental laboratory investigation conducted in vitro. Two isolates demonstrated antibacterial activity: isolate code DR4 inhibited the growth of Escherichia coli (3 ± 0.5 mm), while isolate DR10 inhibited the growth of four bacteria: Bacillus subtilis (5 ± 0 mm), Staphylococcus aureus (1.5 ± 0.5 mm), Escherichia coli (1 ± 0 mm), and Pseudomonas aeruginosa (1 ± 0 mm). Disc diffusion tests using ethyl acetate extracts of isolate DR10 showed the highest antibacterial activity at a concentration of 10,000 ppm. The Minimum Inhibitory Concentration (MIC) was determined to be 156.2 ppm against B. subtilis, while the Minimum Bactericidal Concentration (MBC) was >625 ppm. Molecular identification showed that isolate DR 10 had 100% similarity to Bacillus sp. TS8. The active compound suspected to have antibacterial properties is pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl)-, with the highest abundance.
Perbandingan Lama Rawatan Pasien Sectio Caesarea Metode ERACS dengan Metode Konvensional di RSIA Restu Ibu Padang Harbaindo, Shavira Quincy; Effendi, Rinal; Linosefa, Linosefa; Suharti, Netti; Rustini, Rini; Antonius, Puja Agung
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 4 (2024): Desember 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i4.989

Abstract

Latar Belakang. Angka sectio caesarea yang mengalami peningkatan dari tahun ke tahun mendorong banyaknya potensi yang timbul untuk mengembangkan pelayanan, salah satunya dari aspek kecepatan pemulihan yang ditawarkan metode ERACS (Enhanced Recovery After Caesarean Surgery). Metode ERACS memiliki beberapa perbedaan dari metode konvensional, dan menurut penelitian terdahulu, metode ERACS menunjukan lebih banyak keunggulan yang dapat menguntungkan pasien, salah satunya dari segi lama rawatan. Objektif. Mengetahui perbandingan lama rawatan pasien sectio caesarea metode ERACS dengan metode konvensional di RSIA Restu Ibu Padang. Metode. Jenis penelitian ini adalah analitik observasional dengan desain kohort. Data diambil secara retrospektif dari rekam medik pasien sectio caesarea di RSIA Restu Ibu periode November-Desember 2021. Sampel berjumlah 67 pasien yang dipilih menggunakan total samplingberdasarkan kriteria inklusi dan eksklusi. Hasil. Frekuensi lama rawatan paling tinggi pada pasien sectio caesarea dengan metode konvensional adalah lebih dari atau sama dengan 3 hari, sedangkan lama rawatan pada metode ERACS menunjukan paling banyak pasien dirawat selama 2 hari. Hasil analisis dengan uji Chi-square pada perbandingan lama rawatan antara metode ERACS dengan metode konvensional di rumah sakit tempat penelitian menunjukan nilai p=0,002. Kesimpulan. Kesimpulan dari penelitian ini adalah terdapat hubungan yang signifikan (p<0,05) dari perbandingan lama rawatan antara metode ERACS dengan metode konvensional di RSIA Restu Ibu Padang.
Profil Pasien Diabetes Melitus Tipe 2 dengan Ulkus Kaki Diabetik di RSUP Dr. M. Djamil Padang Tahun 2020-2021 Jannah, Lidya Raudhatul; Elvira, Dwitya; Noer, Mustafa; Decroli, Eva; Saputra, Deddy; Linosefa, Linosefa
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 2 (2024): Juni 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i2.1114

Abstract

Abstrak Latar Belakang: Ulkus kaki diabetik menjadi permasalahan di Indonesia karena sedikitnya tenaga kesehatan yang menggeluti ulkus kaki diabetik, sedikit pengetahuan masyarakat mengenai ulkus kaki diabetik, dan biaya penatalaksanaan yang besar. Objektif: Tujuan penelitian ini adalah untuk mengetahui profil pasien diabetes melitus tipe 2 dengan ulkus kaki diabetik di RSUP Dr.M. Djamil Padang. Metode: Penelitian ini merupakan penelitian deskriptif observatif dengan desain cross-sectional. Sampel penelitian adalah pasien dengan diagnosis ulkus kaki diabetik yang berobat di RSUP Dr.M. Djamil Padang periode 2020-2021. Pengambilan sampel menggunakan teknik total sampling dengan jumlah sebanyak 93 sampel. Data menggunakan jenis univariat dan penyajian data dalam bentuk tabel distribusi frekuensi. Hasil: Hasil penelitian menunjukkan pasien ulkus kaki diabetik paling banyak berada pada usia >55-65 tahun (41,9%), jenis kelamin perempuan (52,7%), tidak bekerja/ IRT (44,1%), tingkat pendidikan terakhir SLTA (55,9%). Derajat ulkus 5 (37,6%), lama rawatan 6-10 hari (40,9%), tekanan darah normal (43,1%). Hasil laboratorium menunjukkan keadaan anemia sedang (47,3%), hipoalbuminemia (96,8%), hiperglikemia (54,8%). Tatalaksana dengan pemberian kombinasi dua antibiotik (59,1%), terapi bedah debridemen (30,2%), kondisi pasien membaik saat dipulangkan (63,4%). Kesimpulan: Kesimpulan penelitian yaitu sebagian besar pasien ulkus kaki diabetik adalah perempuan lansia akhir dengan kondisi anemia, hipoalbuminemia, hiperglikemia. Tatalaksana yang umum diberikan adalah pemberian kombinasi dua antibiotik dan debridemen dengan luaran pasien membaik. Kata kunci: Diabetes melitus tipe 2, pasien ulkus kaki diabetik, profil Abstract Background: Diabetic foot ulcers are a problem in Indonesia because of the lack healthcare professional on diabetic foot ulcers, little public knowledge about diabetic foot ulcers, and high management costs. Objective: The purpose of this study was to determine the profile of type 2 DM patients with diabetic foot ulcers at RSUP Dr.M. Djamil Padang. Methods: This study was an observational descriptive with a cross-sectional design. The research sample was patients diagnosed with diabetic foot ulcers at RSUP Dr.M. Djamil Padang for the 2020-2021 period. The total sampling technique was used to collect a total of 93 samples. The collecting data was analyze by univariat and presented with frequency distribution tables. Results: The results of this study were the most diabetic foot ulcer patients were in the age group >55-65 years (41.9%), female (52.7%), unemployed/housewife (44.1%), and high school education (55.9%). The most ulcer grade 5 (37.6%), treatment duration was 6-10 days (40.9%) and normal blood pressure (43.1%). Laboratory results showed the conditions of moderate anemia (47.3%), hypoalbuminemia (96.8%), and hyperglycemia (54.8%). Management given was a two combination of antibiotics (59.1%), debridementt therapy (30.2%), the patient's condition improved when being discharged (63.4%). Conclusion: This study concluded that the majority of patients with diabetic foot ulcers were elderly women with anemia, hypoalbuminemia, and hyperglycemia. The most common management given was a combination of two antibiotics and debridementt, which resulted in improved patient outcomes. Patients who are at high risk are expected to be more aware of the appearance of symptoms and clinicians are expected to be able to manage patients comprehensively. Keyword : Diabetic foot ulcer patient, profile, type 2 diabetes mellitus
Bacterial Patterns and Sensitivity to Antibiotics in Neonatorum Sepsis Patients at Dr. M. Djamil Padang General Hospital in the Period 2018–2021 Fenty Primadhani; Linosefa, Linosefa; Fitrisia Amelin; Almurdi, Almurdi; Elly Usman; Rahmi Lestari
Jurnal EduHealth Vol. 16 No. 02 (2025): Jurnal EduHealt, Edition April - June , 2025
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Neonatal sepsis is one of the leading causes of morbidity and mortality in neonates. Bacteria are the most common cause of neonatal sepsis. The appropriate empirical therapy is given based on the bacterial pattern and sensitivity at the site. The appropriate use of empirical antibiotics can help reduce the neonatal mortality rate. This study aimed to evaluate bacterial patterns and antibiotic sensitivity in neonatal sepsis patients at RSUP Dr. M. Djamil Padang period 2018-2021. This study is a descriptive study that used a total sampling method with 63 samples that met the inclusion criteria. The results showed that neonatal sepsis was most commonly found in neonates aged 4-28 days, which were mostly male, had a birth weight < 2500 grams, had a mortality rate of 25.4%, and neonatal pneumonia was the most comorbid disease. The most common causative bacteria were Klebsiella pneumoniae and Staphylococcus haemolyticus. Klebsiella pneumoniae is sensitive to amikacin, tigecycline, meropenem, and ertapenem. Staphylococcus haemolyticus was sensitive to tigecycline, nitrofurantoin, vancomycin, linezolid, and quinupristin / dalfopristin. This study concluded that the most common bacteria causing neonatal sepsis were Klebsiella pneumoniae and Staphylococcus haemolyticus. Klebsiella pneumoniae was sensitive to amikacin, tigecycline, meropenem, and ertapenem. Staphylococcus haemolyticus was sensitive to tigecycline, nitrofurantoin, vancomycin, linezolid, and quinupristin / dalfopristin. Clinicians are expected to review the clinical practice guidelines for neonatal sepsis to suit bacterial patterns and their sensitivity to antibiotics.
Perbandingan Nilai Diagnostik Menggunakan Real Time Polymerase Chain Reaction dan Kultur Sebagai Baku Emas dalam Mendeteksi Mycobacterium tuberculosis Tyas, Syanindhita Wikanthining; Linosefa, Linosefa; Tri Anggraini, Fika; Eka Putra , Andani; Bahar, Elizabeth; Arisanty, Dessy; Meinapuri, Malinda
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 2 (2025): Juni 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i2.1400

Abstract

Latar Belakang: Tuberkulosis merupakan penyakit menular yang disebabkan oleh Mycobacterium tuberculosis yang menduduki peringkat kedua penyebab kematian terbanyak. Faktor yang menyebabkan tingginya angka kejadian adalah keterlambatan dalam penegakan diagnosis. Pemeriksaan baku emas untuk tuberkulosis adalah kultur Lowenstein-Jensen yang membutuhkan waktu cukup lama untuk pertumbuhan koloni bakteri. Objektif: Penelitian ini bertujuan untuk mengetahui sensitivitas dan spesifisitas dari RT PCR menggunakan kit RT PCR yang bermerk Kit Crown Lab TB Dx dibandingkan dengan Kultur Lowenstein-Jensen. Metode: Penelitian ini menggunakan metode pendekatan cross-sectional dengan teknik purposive sampling sebanyak 87 sampel dari data sekunder yang diolah dan dianalisis dengan rumus uji diagnostik. Hasil: Hasil RT PCR didapatkan nilai positif 44 orang (50,6%) dan nilai negatif 43 orang (49,4%). Kultur Lowenstein- Jensen didapatkan nilai positif 43 orang (49,4%) dan nilai negatif 44 orang (50,6%). Hasil perbandingan kedua metode didapatkan nilai sensitivitas sebesar 97%, spesifisitas 95%, nilai duga positif 95%, dan nilai duga negatif 97% Kesimpulan: Kesimpulan dari penelitian ini Real Time PCR memiliki sensitivitas, spesifisitas, dan nilai duga positif dan negatif yang tinggi dan memiliki kelebihan waktu pemeriksaan yang lebih cepat dibandingkan pemeriksaan dengan Kultur Lowenstein-Jensen.  
Cycle Threshold Value and Absolute Lymphocyte Count Relationship with Severity of COVID-19 M. Alfian Agustian; Andani Eka Putra; Cimi Ilmiawati; Novita Ariani; Linosefa Linosefa
Vitalitas Medis : Jurnal Kesehatan dan Kedokteran Vol. 2 No. 3 (2025): Juli: Vitalitas Medis : Jurnal Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/vimed.v2i3.1964

Abstract

Coronavirus Disease 2019 (COVID-19) is a case that spread to many countries, including Indonesia, due to of SARS-CoV-2 transmission. West Sumatra, especially Padang city, is one of the highest spread of COVID-19 cases in Indonesia. This study aimed to examine the relation between Ct value and absolute lymphocyte count with the severity of COVID-19. The type of this research was analytic observational with the cross sectional study. We collected 106 patients data in Dr. M. Djamil Padang hospital from moderate to critical severity from June-August 2021. The data were collected and processed using convenient sampling which was then tested using Spearman correlation, One Way ANOVA, and Kruskal-Wallis tests. The results showed that most patients with confirmed COVID-19 were at the age of 56 to 65 years (30.2%), were women (51.9%), and had hypertension comorbidity (27.6%). We found that the median (IQR) of the Ct value is 23.5(10) and the mean ± SD of absolute lymphocyte count is 1213±56. There was a relation between Ct value and severity of COVID-19 (p=0.019), absolute lymphocyte count and severity of COVID-19 (p<0.01), and weak negative correlation of Ct value and absolute lymphocyte count (p=0.040, r=-0.200). Increasing viral load may elicit higher immune response clinically in moderate to critical COVID-19 patients.