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Rina Wijayanti
Universitas Islam Sultan Agung
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Sciences of Pharmacy

 1 
Antibacterial and Antifungal Activities of Pandanus amaryllifolius Leaf Extract, Fractions, and Isolate and Their Role in Anti-Dandruff Shampoo Optimization Wijayanti, Rina; Susmayanti, Windi; Meliana, Dias Feni; Fauziyah, Afifah Husnun; Anjeline, Aprilia Mega; Putri, Devyra Yunika Mutiara Sari Suwarto; Ulya, Fadhia Tafrichatul
Sciences of Pharmacy Volume 4 Issue 2
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0402299

Abstract

Pandan leaves (Pandanus amaryllifolius Roxb.) possess various biological activities due to their secondary metabolites, including flavonoids, alkaloids, phenolics, saponins, and triterpenoids/steroids. This study aimed to evaluate the antibacterial and antifungal activities of pandan leaf extracts, fractions, and isolates against Staphylococcus aureus, Escherichia coli, and Pityrosporum ovale, as well as to optimize surfactants in shampoo formulations. The experimental design used a post-test-only control group. Samples were processed through maceration, followed by fractionation and isolation using the KLT-P method. Antibacterial and antifungal activities were assessed using the agar well diffusion method. The most effective antibacterial activity against E. coli was observed in the n-hexane isolate at 700 ppm, with an inhibition zone of 19.6 mm, classified as strong. For S. aureus, the 100% water fraction produced an inhibition zone of 9.96 mm, classified as weak. The ethanol extract showed antifungal activity against P. ovale with an inhibition zone of 6.29 mm, categorized as moderate. Shampoo formulation optimization using sodium lauryl sulfate and cocamide DEA resulted in an ideal ratio of 0.235 to 0.764. This combination produced a shampoo with acceptable physical characteristics, including a pH of 5.71, foam height of 2.56 cm, and viscosity of 899.9 cps, all of which met the standard requirements.
Co-Authors Abdur Rosyid Abdur Rosyid Aeni, Saniatul akbar, mochammad ramli Akbar, Mochammad Ramly Akbar, Muchammad Ramli Alina, Rusda Anggun Dwi V Angrraeni, Yunita Dwi Anjeline, Aprilia Mega Antares, Dendy Andrea Antika, Erma Beti Trindi Anugraini, Asri Putri Apriadi, Awal Asih Puji Lestari asmah, ayu Budiastiyani, Riri Hartati Chilmia Nurul Fatiha Cipta, Dyah Ayu Sulistyaning Dedi Rusdi Desi Nurferawati Dheanggara Resty Dina Raidanti Edijanti Goenarwo Eko Harianto, Eko Fauziyah, Afifah Husnun Febrinasari, Angelica Merry Febrinasari, Nisa Fuadah, Farikha Sitra haryono, sarah emmanuel Henni Anggraini, Henni Hesti Ratnasari, Hesti Hidayati, Selvi Nuri Ida Royani Iffa Kholishotul Izza Irawan, Amindra Izza, Iffa Kholishotul Jayanti, Christin Kartika, Era Dewi Khusniyah, Mufidatul Lada, Maria Sabarina Rato Lailia, Nihayatul Lasiana, Dian Ning Legowo, M. E. Putri Ayu Lestari Maran, Meliana Hadung Maynia Susanti Meliana, Dias Feni Mika Ambarawati, Mika Muhana Gipayana, Muhana Muhardjito Muhardjito Mulya Prayoga, Deden Mumpuni, Wanda Danis Musyarrafah, Musyarrafah Nikmah, Ilya Syafa?atun Nikmah, Ilya Syafa’atun Ningrum, Ika Lestari Ningtyas, Ery Ardiyanti Nurferawati, Desi Nuzlil Laily Nur Azizah, Nuzlil Laily Nur P, Nabilla Andasari Palui, Yustina Kartini Pebrianti, Chindi Pertiwi, Dita Yati Pratiwi, Sela Firnanda Prayoga, Deden Mulya Priyatno, Sugeng Putri Anugraini, Asri Putri, Devyra Yunika Mutiara Sari Suwarto Rachmawati Rachmawati Rahayunita, Cicilia Ika Rahman, Fariya Azzuri Ramadhaniati, Dian Pratiwi Res, Viktoria Resty, Dheanggara Ridwan, Sucilawaty Rochsun, Rochsun Rokhmawati, Yudies Rosa, Selvi Alkailia Rosyid, Abdur Safwan Safwan, Safwan Salim, Muhamad Samsul Nur Saniatul Aeni Saputri, Seftiyaningsih Duwi Saraswati, Herluin Nadia Septiana, Yunia Shihab, Aura Najwa Siti Kurniasih SITI MUNTOMIMAH, SITI Slamet Santosa Sri Widoretno Suparti, S Susanti, Maynia Susmayanti, Windi Sutanto, Gusnul Syarifah, Muslihatus Ulya, Fadhia Tafrichatul Ulyana, Dewi Umari, Intan V, Anggun Dwi Wahidin, Wahidin Wardani, Novia Kusuma Widyaning Hapsari, Widyaning Widyaningrum, Kinar Santi Wuryani, Tri Yulianti, Beti Zahrotul Mufidah