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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. E-Jurnal Medika Udayana Jurnal Kedokteran Brawijaya Jurnal Kesehatan Masyarakat Damianus Journal of Medicine Nusantara Medical Science Journal Jurnal Kesehatan Manarang Majalah Kesehatan Pharmamedika Jurnal Ilmiah Kesehatan (JIKA) Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Molucca Medica Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Physical Therapy Journal of Indonesia Neurona Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Andi Alfian Zainuddin
Bagian Ilmu Kesehatan Masyarakat/Ilmu Kedokteran Komunitas Fakultas Kedokteran Universitas Hasanuddin
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Nusantara Medical Science Journal

 1 
Right Ventricle Free Wall Longitudinal Strain in Cancer Patients Following Chemotherapy Ghaznawie, Aussie Fitriani; Muzakkir, Akhtar Fajar; Fathlina, F.; Mappahya, Ali Aspar; Alkatiri, Abdul Hakim; Zainuddin, Andi Alfian; Prihantono, Prihantono
Nusantara Medical Science Journal Volume 8 Issue 1, January - June 2023
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v8i1.26648

Abstract

Introduction: The survival rate of cancer patients was high due to chemotherapy, but it can cause cardiotoxicity and increase morbidity and mortality. Most studies on cancer therapy-related cardiac dysfunction (CTRCD) focus more on the left ventricle. This study assesses chemotherapy's effect on the right ventricle, namely the right ventricle free wall longitudinal strain (RVFWLS). Methods: This study is a prospective cohort conducted from January to December 2022 on thirty-four cancer patients undergoing chemotherapy at Dr Wahidin Sudirohusodo Hospital Makassar. The RVFWLS was assessed before and after chemotherapy using echocardiographic. Result: The RVFWLS value after one cycle chemotherapy decreased compared pre-chemotherapy (4.40±4.84; p=0.001). Conclusion: The effect of chemotherapy is a decrease the RVFWLS value after the first cycle of chemotherapy. It should be considered for echocardiographic evaluation, especially the RVFWLS value every cycle of chemotherapy.
Immunohistochemical Diagnostic value of Calretinin in Hirschprung Disease Azis, Zainab; Cangara, M. Husni; Zainuddin, Andi Alfian; Wahid, Syarifuddin; Mariana, Nita; Miskad, Upik A.
Nusantara Medical Science Journal Volume 8 Issue 2, July - December 2023
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.vi.20000

Abstract

Introduction: Hirschsprung's disease (HD) is characterized by the absence of ganglion cells in Meissner's plexus and Auerbach's plexus which used to be assessed by histopathological examination using Hematoxylin and Eosin (H&E).  In some cases is difficult to assess ganglion cells, thus requiring additional examination in the form of calretinin immunohistochemistry to detect the presence of ganglion. Methods: The 59 samples of suspected HD  were analyzed by H&E staining followed by calretinin immunohistochemical staining. This study aimed to assess the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of calretinin in HD diagnostics. Results:  The immunohistochemistry of calretinin showed a good diagnostic value in detecting aganglionosis in patients with suspected HD with a sensitivity value = 97.7%; Specificity = 100%; Positive Presumptive Value (PPV) = 100%; Negative Presumptive Value (NPV) = 93.7%; Accuracy= 98.3%. Thus, calretinin immunohistochemistry can be relied upon as an additional method in the diagnosis of HD
Significance of HBsAg Expression in Placental Tissue with Serum Positivity in Hepatitis B Virus-infected Mother Kalatiku, Jane Magdalena; J Nelwan, Berti; Zainuddin, Andi Alfian; Kaelan, Cahyono; Achmad, Djumadi; Masadah, Rina
Nusantara Medical Science Journal Volume 8 Issue 2, July - December 2023
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.vi.20242

Abstract

Introduction:  Hepatitis B virus infection in fetal and newborn may result from the intrauterine vertical transmission. The purpose of our study is to determine the association between HBsAg expression in the placental and HBsAg serum in pregnant women. Methods: Total 67 placental tissues and serum were obtained from HBV-infected mothers. This study was conducted in various hospitals in Makassar, Indonesia from December 2017 until August 2018. Maternal serum and placental tissues were tested by ELISA and Immunohistochemistry staining. Results: 67 samples from placental tissues and serum were categorized into two different levels of serum titer and staining positivity. Twenty nine samples (43.3%) were categorized in low titer of HBsAg positive serum and 38 samples (56.7%) in high titer of  HBsAg positive serum. From the total of 67 placental samples, 43 (64.2%) samples had positive expression of HBsAg immunohistochemistry staining and 24 (34.8%) samples had negative expressions. Conclusions: There was a significant correlation between the expressions of HBsAg in the placental tissues and serum titers of HBV-infected mothers that is important in predicting the risk of transplacental transmission. The results of this study can be used as guidelines for the prevention and therapeutic approach of mother-to-child HBV infection.
Co-Authors A.A. Ketut Agung Cahyawan W Abdul Hakim Alkatiri Achmad, Djumadi AL, Suardi Ali Aspar Mappahya Amalia Amalia Amin, Muzakkir AMIN, ROSMINI Amran, Muhammad Yunus Anaam, Andi Khairul Andi Kurnia Bintang, Andi Kurnia Arif, Asnita Aritonang, Sylvia Evelyn Asriyani, Sri Asriyani, Sri Asriyanti, Sri Assegaf, S. Zulfikar. G. Azis, Zainab Baan, Junus Bachtiar Murtala Bachtiar, Nur Amelia Bahar, Ashari Bakri, Dina Fatiyah Basri, Muhammad Iqbal Blow, David Burhanudin, Danang P Cahyono Kaelan, Cahyono Cangara, Husni Cangara, M. Husni Darmawan, Andi Miftah Khaerati Dase, Jerny David Gunawan Umbas Djaharuddin, Irawati Djaharuddin, Irawaty Fadjar Perkasa, Muhammad Fathlina, F. Ghaznawie, Aussie Fitriani Goysal, Yudy Halim, Wijoyo Harun Muchsin, Achmad Hasan, Rumaisah Herman, Teddy Marzuki Herpan Syafii Harahap HP, Faridin Husnah, Kurniawati Idham Jaya Ganda, Idham Jaya Idris, Nurlaily Irsyadat, Andi Muhammad J Nelwan, Berti Johan, Muhammad Phetrus Juniarsih, Juniarsih Kai, Rosita Kalatiku, Jane Magdalena Kasim, Hasyim Kasim, Muhammad Firdaus Latief, Nikmatia Latief, Nikmatia Lawrence, Gatot. S. Liong Boy Kurniawan, Liong Boy Lotisna, Mimi Madeng, A. Arsidin Mappa Mayasari, Nilla Melda Warliani Meryana*, A. Kurnia Bintang**, Muh. Akbar**, Susi Aulina**, Yudy Goysal**, Arifin Limoa*** Miskad, Upik Mubarak, Husnul Muhammad Akbar Muhammad Fadhil Muhammad Fadjar Perkasa, Muhammad Fadjar Muhammad Ilyas Muis, Mirna Mustamir, Nasrullah Mutaher, Annisa Anwar Muzakkir, Akhtar Fajar Nelwan, Berty. J Nikmatiyah, Wa Ode Sri Nita Mariana Nurdin, Nurhaya Ogirahma Prihantono, Prihantono Rafiah, Sitti Rauf, Rafikah Rina Masadah Sahlan, Anshory Said, Suryani Sam, Nuralam Samban, Ida Shanti Riskiyani Shinta, Pricilla Solly Aryza Soma, Andang Suryana Sri Ramadany, Sri Syarifuddin Wahid talawo, Vivi Yuniarti Tammasse, Jumraini Tanady, Kevin Julius Tarigan, Ngalasantaru Janstar Tiorisman, Nola Uleng Bahrun, Uleng Upik A. Miskad, Upik A. Walenna, Nirwana Fitriani Waluyo, Yose Wangsa, Jeanie Dewi Wuysang, Audry Devisanty Yundari, Yundari