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All Journal Jurnal Riset Kesehatan THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Meditory : The Journal of Medical Laboratory Jurnal Kesehatan Prima Jurnal Mandala Pharmacon Indonesia Jurnal Analis Medika Biosains (JAMBS) Jurnal Pengabdian Masyarakat Multidisiplin Jurnal Pengabdian Masyarakat Sasambo Quality : Jurnal Kesehatan Jurnal Kefarmasian Indonesia Journal of Indonesia Laboratory Students (JILTS) Jurnal Indonesia Mengabdi Galen: Jurnal Ilmu Farmasi dan Kesehatan
Dewi, Lale Budi Kusuma
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Pengaruh Lama Diet Intermittent Fasting terhadap Kadar Glukosa Darah Puasa Aqila Fadia; Lale Budi Kusuma Dewi; I Wayan Getas; Nurul Inayati
Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 2 (2025): Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : PT Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71417/galen.v1i2.62

Abstract

Intermittent fasting (IF) merupakan metode diet dengan pembatasan waktu makan, salah satunya adalah metode 16:8. Diet ini diduga berpotensi mengurangi kadar glukosa darah berkat peningkatan aktivitas insulin dan perubahan metabolisme energi. Durasi pelaksanaan diet menjadi faktor penting dalam pencapaian hasil metabolik yang optimal. Tujuannya untuk mengetahui pengaruh lama diet intermittent fasting terhadap kadar glukosa darah puasa. Penelitian ini menggunakan desain observasional analitik dengan pendekatan prospektif. Sebanyak 30 responden yang menjalani diet IF metode 16:8 diperiksa kadar glukosa darah puasanya sebelum diet, setelah 2 minggu, dan setelah 4 minggu menggunakan metode enzimatik GOD-PAP. Data dianalisis menggunakan uji Shapiro-Wilk untuk normalitas dan uji ANOVA untuk mengetahui signifikansi perbedaan. Terdapat penurunan rerata kadar glukosa darah puasa dari 119,1 mg/dl (sebelum diet) menjadi 108,63 mg/dl (setelah 2 minggu), dan 98,37 mg/dl (setelah 4 minggu). Uji ANOVA menunjukkan perbedaan yang signifikan antar ketiga waktu pengukuran (p < 0,001). Lama pelaksanaan diet intermittent fasting berpengaruh signifikan terhadap penurunan kadar glukosa darah puasa. Diet IF metode 16:8 selama 4 minggu terbukti bisa menurunkan kadar glukosa darah puasa secara bermakna dan dapat dijadikan alternatif non-farmakologis dalam pengelolaan glukosa darah.
Effect of Instant Coffee Consumption Duration on Low Density Lipoprotein (LDL) and Triglyceride Levels in the Community in Tanjung District, North Lombok Regency Suaryana, I Made Chandra; Wiadnya, Ida Bagus Rai; Dewi, Lale Budi Kusuma; Rohmi, Rohmi
Jurnal Analis Medika Biosains (JAMBS) Vol 12, No 2 (2025): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v12i2.475

Abstract

Long-term coffee consumption is thought to affect health, on blood fat levels such as Low Density Lipoprotein (LDL) cholesterol and Triglycerides. Knowing the effect of length of instant coffee consumption on Low Density Lipoprotein (LDL) and Triglyceride levels in the community in Tanjung District, North Lombok Regency. Analytic observation with a cross-sectional approach. Non-random sampling technique with a sample size of 30 respondents. Data analysis of one way anova test. Average Low Density Lipoprotein (LDL) levels in instant coffee consumers 1 year 175.5 mg/dl, 2 years 227.9 mg/dl, 3 years 296.2 and triglycerides 1 year 107.5 mg/dl, 2 years 165.8 mg/dl, 3 years 159.1 mg/dl. The results of the one-way anova test obtained a sig value of 0.006 ≤ 0.05 and triglycerides 0.007 ≤ 0.05.there is a significant effect of length of instant coffee consumption (1 year, 2 years, and 3 years) on Low Density Lipoprotein (LDL) and Triglyceride levels in the community in Tanjung District, North Lombok Regency. Where the longer the consumption of instant coffee, the higher the levels of Low Density Lipoprotein (LDL) and Triglycerides increased in the first year of instant coffee consumption, but decreased in the third year. This change may be influenced by body adaptation and other factors such as diet, physical activity, and health conditions.
Pengaruh Konsumsi Timun dan Bawang Merah terhadap Penurunan Kadar Kolesterol Pasien di Wilayah Kerja Puskesmas Babakan Nandini, Ni Kadek; Zaetun, Siti; Inayati, Nurul; Lale Budi Kusuma Dewi
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 1 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v3i1.44

Abstract

Hypercholesterolemia is caused by the liver not being able to control LDL in the blood vessels, this condition will cause atherosclerosis and cardiovascular disease. Sterols and flavonoids are content that found in cucumbers which can lower cholesterol by replacing sterols with LDL which will be absorbed in the digestive system. The LDL will be excreted in the form of feces with the help of flavonoids And quercetin is a content found in red onions that can reduce cholesterol levels in the blood by inhibiting the HMG Co-A reductase enzyme. Yankestrad is a program at the Babakan Public Health Center include the use of medicinal plants (TOGA) such as cucumbers and red onions. The purpose of this study is to know the effect of cucumber and red onions consumption on reducing cholesterol levels in patients in the Babakan Health Center work area through the Yankestrad program. Research methods are analytical observational with case control research design and purposive sampling methods. The results of this there is an effect of consuming cucumber and red onions on reducing cholesterol levels.
Uji Sensitivitas dan Spesitifitas Immuno Chromatography Test -Tuberculosis (ICT - TB) pada Penderita Tuberkulosis Paru di Kabupaten Bima-NTB Fitri; Rohmi; Ariami, Pancawati; Kusuma Dewi, Lale Budi
Journal of Indonesia Laboratory Students (JILTS) Vol. 4 No. 1 (2025): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v4i1.213

Abstract

Background: The problem of Tuberculosis (TB) is a healt problem thathas long been faced by various countries in the world, includingIndonesia. Tuberculosis is an infectious disease caused by infectionwith the germ Mycobacterium tuberculosis. Tuberculosis disease mostlyaffects the lung parenchyma (pulmonary TB). ICT-TB is a serologicaltest that is fast, simple and easy bto operate. The limited of number ofGenexpert MTB in Bima regency is an obstacle in establishing an earlytuberculosis. Objective: To determinan the sensitivity and specificity of the immunochromatography test-tuberculosis (ICT-TB) method in TB patients. Method: This study is an analytical abservational study, with apurposive sampling approach, namely research samples taken fromserum specimens for the ICT-TB method and sputum for GenexpertMTB as standart. The sensitivity and specificity for ICT-TB werecalculated manually using the Mc nemar formula in the 2 x 2 diagnostictest table. Results: The ICT- TB result showed 4 positive IgG respondents and 41negative respondents, while the Genexpert MTB result showed 6 MTBDetected and 39 MTB Not Detected. The ICT-TB sensitivity test resultfor TCM were 50% and specificity 97,44%. Conclusion: ICT-TB method has excellent specificity value. However ,the ICT-TB method examination still has shortcomings that are notfound in the Genexpert MTB method.Recommendation: Further research needs to be carried out usingsamples of tuberculosis positive patients who have not receivedtreatment.
PENGGUNAAN SONGGAK SUKU SASAK UNTUK MENURUNKAN KADAR GULA DARAH PENDERITA DIABETES MELLITUS DI KELURAHAN DASAN CERMEN, KOTA MATARAM Kusuma Dewi, Lale Budi; Khusuma, Ari; Agrijanti, Agrijanti; Wulandari, Ayu Nurislami
Jurnal Pengabdian Masyarakat Sasambo Vol. 5 No. 2 (2024): Mei
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jpms.v5i2.1502

Abstract

Data dari profil Puskesmas Babakan, tingkat obesitas penduduk, dari 3.824 yang diperiksa, ditemukan 1.053 orang (27%) diantaranya dinyatakan obesitas. Sebanyak 90-95% kasus diabetes adalah DM tipe 2, yang sebagian besar dapat dicegah karena disebabkan oleh gaya hidup yang tidak sehat.  Tujuan pengabdian ini sebagai upaya membantu mengendalikan kadar gula darah penderita hiperglikemia dengan ramuan tradisional suku sasak, Songgak. Sebanyak 45 masyarakat yang hadir dalam kegiatan sosialisasi diperiksa kadar gukosa darahnya, sebanyak 14 orang memiliki kadar gula darah sewaktu ≥200mg/dl. Songgak disosialisasikan dan disampaikan hasil penelitian tentang manfaat songgak untuk menurunkan kadar glukosa darah. Setelah konsumsi songgak selama dua  minggu, terjadi penurunan kadar glukosa darah sewaktu pada 21 peserta. Masyarakat paham pentingnya menjaga pola hidup dan pentingnya pemeriksaan glukosa darah secara berkala bagi penderita DM. Data profile of the Babakan Health Center, the obesity level of the population, of the 3,824 examined, 1,053 people (27%) were found to be obese. As many as 90-95% of diabetes cases are type 2 DM, most of which can be prevented because they are caused by an unhealthy lifestyle. The purpose of this service is as an effort to help control blood sugar levels of hyperglycemia sufferers with the traditional ingredients of the Sasak tribe, Songgak. As many as 45 people who attended the socialization activity had their blood glucose levels checked, as many as 14 people had blood sugar levels when ≥200mg/dl. Songgak was socialized and presented the results of research on the benefits of Songgak for lowering blood glucose levels. After consuming Songgak for two weeks, there was a temporary decrease in blood glucose levels in 21 participants. The community understands the importance of maintaining a lifestyle and the importance of regular blood glucose checks for people with DM.
The Effect of Roasting Methods of Ingredients The Songgak Tribe Sasak Herbal on Active Compounds Using Gas Chromatography Mas Spectroscopy (Gc-Ms) Analysis) Agrijanti, Agrijanti; Kusuma Dewi, Lale Budi; Khusuma, Ari; Wardoyo, Eustachius Hagni
Jurnal Kesehatan Prima Vol. 18 No. 2 (2024): AUGUST
Publisher : poltekkes kemenkes mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jkp.v18i2.1540

Abstract

Songgak is a concoction of the Sasak tribe of Lombok in West Nusa Tenggara. It consists of coffee mixed with groundwood, cloves, black pepper, coriander, and nutmeg. The original recipe involves roasting the spices before mixing them with coffee, namely using a frying pan over a stove. The roasting process is carried out without controlling the temperature and roasting time, so the roasted ingredients need to be standardized(Dewi et  al., 2021). GCMS is a tool used to analyze compounds in samples using chemical separation methods, mainly chromatography. The compounds in the mixture are separated in a chromatographic column. The separation mechanism between several compounds occurs due to differences in the solubility values of each in the moving solvent and differences in the absorption of each of the competing compounds into the stationary phase (Gross, 2017). In this research, variations will be carried out on spices, namely T1 original treatment of roasting spices over fire for 8 minutes, T2 drying spices in sunlight, T3 oven for 5 minutes, T5 oven for 5 minutes, T4 oven for 15 minutes and T5 oven for 15 minutes. In the T4 treatment, namely oven for 10 minutes, the results of the analysis of the substance content with the most types, namely 20 types, were obtained. The active anti-microbial compound found in all treatments was Hexadecanoic acid, 2-hydroxy-1-(h)(C19 H38 O4) BM:330, which helps inhibit the growth of cancer cells. (National Library Medicine, n.d.). Octadecanoic acid (CAS) Stear (C18 H34 O2) BM:282 Anti-inflammatory, Antiandrogenic Cancer prevention, Hypocholesterolemia Dermatigenic, 5-Alpha reductase inhibitor, Anemiagenic, Insecticide (Natarajan et al., 2019) and Tetradecanoic acid (CAS) Myris (C14 H28 O2) BM:228 as anti-inflammatory and anti-nociceptive. 
Odds Ratio of Increase in Hemoglobin Level Associated with Consumption of Songgak Coffee in Patients with Pulmonary TB Dewi, Lale Budi Kusuma; Hartuti, Sri; Getas, I Wayan; Agrijanti, Agrijanti; Tatontos, Erlin Yustin; Wiadnya, Ida Bagus Rai; Zaetun, Siti; Khusuma, Ari
Jurnal Kefarmasian Indonesia VOLUME 15, NUMBER 1, FEBRUARY 2025
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pulmonary TB cases in Indonesia are the second highest in the world. The incidence of Anemia in pulmonary TB patients can be as high as 90%. Anemia can lead to poor outcomes in the recovery of pulmonary TB. Songgak coffee is a coffee with a mixture of spices that is commonly consumed by the people of Central Lombok to make the body healthy and increase vitality, including pulmonary TB patients. Songgak coffee is made from 7 types of spices mixed with coffee. The results of previous research show that Songgak coffee has quite good antioxidant content and is an immunostimulant. Antioxidants may increase Hemoglobin levels. This was a case-control study. A total of 26 new pulmonary TB patients were divided into 2 groups. Group A received songgak coffee as an additional anti-TB drug, while group B received anti-TB drug therapy alone. Hemoglobin levels in groups A and B were measured before drug administration and 14 days after treatment. The data collected were nominal data, reported as increasing and non-increasing. A total of 12 out of 13 patients in group A had an increase in Hemoglobin, while only 1 person in group B had an increase in Hemoglobin. The odds ratio value for increasing Hemoglobin levels in pulmonary TB patients who consume songgak is 12. The odds ratio value for increasing Hemoglobin in pulmonary TB patients taking songgak is 12. The odds ratio value for increasing Hemoglobin levels in pulmonary TB patients who take Songgak is 12 times higher than in pulmonary TB patients who do not take Songgak.
Co-Authors Agrijanti, Agrijanti Aqila Fadia Ari Khusuma Awan Dramawan Baiq Linda Rolian ocatari Erlin Yustin Tatontos Eustachius Hagni Wardoyo Fadhilah Rizkiyah Fakhmi, Shausan Nabila Fihiruddin, Fihiruddin Fitri Getas, I Wayan Gunarti Gunarti I Gusti Ayu Ratih Yuliartini Ayu I Made Suardika I Wayan Getas I Wayan Getas Intan Suryawatie Yomo, Meidiana Iswari Pauzi Iswari Pauzi Lalu Sri Gede Lalu Srigede Lalu Srigede Lalu Srigede Lalu Srigede, Lalu Lidia Febrianisa Maruni Wiwin Diarti Maruni Wiwin Diarti Meidiana Intan Suryawatie Yomo Muhammad Luthfi Nandini, Ni Kadek Ni Kadek Defyantari Ni Luh P. Sri Ayu Sutami D Ni Luh Putu Pebrita Nurul Inayati Nurul Inayati Nurul Inayati Nurul Inayati Pancawati Ariami Pancawati Ariami Permatasari, Lina Pramoswari, Dining RAI WIADNYA, IDA BAGUS Rohmi Rohmi, Rohmi Safitri, Wiwin Safitri, Wiwin Siti Karyani Siti Zaetun Siti Zaetun Siti zaetun Siti Zaetun Siti Zaetun, Siti Sri Hartuti Suaryana, I Made Chandra Thomas Tandi Manu Vani Nurcahyanti Viefa Avrilian Alifah Wadnya, Ida Bagus Rai Wayan Getas Wiwin Safitri Wulandari, Ayu Nurislami Yudha Anggit Jiwantoro Yunan Jiwintarum Zaenal Fikri Ziana Dia Ningsih