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All Journal Jurnal Riset Kesehatan THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Meditory : The Journal of Medical Laboratory Jurnal Kesehatan Prima Jurnal Mandala Pharmacon Indonesia Jurnal Analis Medika Biosains (JAMBS) Jurnal Pengabdian Masyarakat Sasambo Quality : Jurnal Kesehatan Jurnal Kefarmasian Indonesia Journal of Indonesia Laboratory Students (JILTS) Jurnal Indonesia Mengabdi Galen: Jurnal Ilmu Farmasi dan Kesehatan
Dewi, Lale Budi Kusuma
POLTEKKES KEMENKES MATARAM
Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Effect of Instant Coffee Consumption Duration on Low Density Lipoprotein (LDL) and Triglyceride Levels in the Community in Tanjung District, North Lombok Regency Suaryana, I Made Chandra; Wiadnya, Ida Bagus Rai; Dewi, Lale Budi Kusuma; Rohmi, Rohmi
Jurnal Analis Medika Biosains (JAMBS) Vol 12, No 2 (2025): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v12i2.475

Abstract

Long-term coffee consumption is thought to affect health, on blood fat levels such as Low Density Lipoprotein (LDL) cholesterol and Triglycerides. Knowing the effect of length of instant coffee consumption on Low Density Lipoprotein (LDL) and Triglyceride levels in the community in Tanjung District, North Lombok Regency. Analytic observation with a cross-sectional approach. Non-random sampling technique with a sample size of 30 respondents. Data analysis of one way anova test. Average Low Density Lipoprotein (LDL) levels in instant coffee consumers 1 year 175.5 mg/dl, 2 years 227.9 mg/dl, 3 years 296.2 and triglycerides 1 year 107.5 mg/dl, 2 years 165.8 mg/dl, 3 years 159.1 mg/dl. The results of the one-way anova test obtained a sig value of 0.006 ≤ 0.05 and triglycerides 0.007 ≤ 0.05.there is a significant effect of length of instant coffee consumption (1 year, 2 years, and 3 years) on Low Density Lipoprotein (LDL) and Triglyceride levels in the community in Tanjung District, North Lombok Regency. Where the longer the consumption of instant coffee, the higher the levels of Low Density Lipoprotein (LDL) and Triglycerides increased in the first year of instant coffee consumption, but decreased in the third year. This change may be influenced by body adaptation and other factors such as diet, physical activity, and health conditions.
Pengaruh Konsumsi Timun dan Bawang Merah terhadap Penurunan Kadar Kolesterol Pasien di Wilayah Kerja Puskesmas Babakan Nandini, Ni Kadek; Zaetun, Siti; Inayati, Nurul; Lale Budi Kusuma Dewi
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 1 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v3i1.44

Abstract

Hypercholesterolemia is caused by the liver not being able to control LDL in the blood vessels, this condition will cause atherosclerosis and cardiovascular disease. Sterols and flavonoids are content that found in cucumbers which can lower cholesterol by replacing sterols with LDL which will be absorbed in the digestive system. The LDL will be excreted in the form of feces with the help of flavonoids And quercetin is a content found in red onions that can reduce cholesterol levels in the blood by inhibiting the HMG Co-A reductase enzyme. Yankestrad is a program at the Babakan Public Health Center include the use of medicinal plants (TOGA) such as cucumbers and red onions. The purpose of this study is to know the effect of cucumber and red onions consumption on reducing cholesterol levels in patients in the Babakan Health Center work area through the Yankestrad program. Research methods are analytical observational with case control research design and purposive sampling methods. The results of this there is an effect of consuming cucumber and red onions on reducing cholesterol levels.
Uji Sensitivitas dan Spesitifitas Immuno Chromatography Test -Tuberculosis (ICT - TB) pada Penderita Tuberkulosis Paru di Kabupaten Bima-NTB Fitri; Rohmi; Ariami, Pancawati; Kusuma Dewi, Lale Budi
Journal of Indonesia Laboratory Students (JILTS) Vol. 4 No. 1 (2025): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v4i1.213

Abstract

Background: The problem of Tuberculosis (TB) is a healt problem thathas long been faced by various countries in the world, includingIndonesia. Tuberculosis is an infectious disease caused by infectionwith the germ Mycobacterium tuberculosis. Tuberculosis disease mostlyaffects the lung parenchyma (pulmonary TB). ICT-TB is a serologicaltest that is fast, simple and easy bto operate. The limited of number ofGenexpert MTB in Bima regency is an obstacle in establishing an earlytuberculosis. Objective: To determinan the sensitivity and specificity of the immunochromatography test-tuberculosis (ICT-TB) method in TB patients. Method: This study is an analytical abservational study, with apurposive sampling approach, namely research samples taken fromserum specimens for the ICT-TB method and sputum for GenexpertMTB as standart. The sensitivity and specificity for ICT-TB werecalculated manually using the Mc nemar formula in the 2 x 2 diagnostictest table. Results: The ICT- TB result showed 4 positive IgG respondents and 41negative respondents, while the Genexpert MTB result showed 6 MTBDetected and 39 MTB Not Detected. The ICT-TB sensitivity test resultfor TCM were 50% and specificity 97,44%. Conclusion: ICT-TB method has excellent specificity value. However ,the ICT-TB method examination still has shortcomings that are notfound in the Genexpert MTB method.Recommendation: Further research needs to be carried out usingsamples of tuberculosis positive patients who have not receivedtreatment.
PENGGUNAAN SONGGAK SUKU SASAK UNTUK MENURUNKAN KADAR GULA DARAH PENDERITA DIABETES MELLITUS DI KELURAHAN DASAN CERMEN, KOTA MATARAM Kusuma Dewi, Lale Budi; Khusuma, Ari; Agrijanti, Agrijanti; Wulandari, Ayu Nurislami
Jurnal Pengabdian Masyarakat Sasambo Vol. 5 No. 2 (2024): Mei
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jpms.v5i2.1502

Abstract

Data dari profil Puskesmas Babakan, tingkat obesitas penduduk, dari 3.824 yang diperiksa, ditemukan 1.053 orang (27%) diantaranya dinyatakan obesitas. Sebanyak 90-95% kasus diabetes adalah DM tipe 2, yang sebagian besar dapat dicegah karena disebabkan oleh gaya hidup yang tidak sehat.  Tujuan pengabdian ini sebagai upaya membantu mengendalikan kadar gula darah penderita hiperglikemia dengan ramuan tradisional suku sasak, Songgak. Sebanyak 45 masyarakat yang hadir dalam kegiatan sosialisasi diperiksa kadar gukosa darahnya, sebanyak 14 orang memiliki kadar gula darah sewaktu ≥200mg/dl. Songgak disosialisasikan dan disampaikan hasil penelitian tentang manfaat songgak untuk menurunkan kadar glukosa darah. Setelah konsumsi songgak selama dua  minggu, terjadi penurunan kadar glukosa darah sewaktu pada 21 peserta. Masyarakat paham pentingnya menjaga pola hidup dan pentingnya pemeriksaan glukosa darah secara berkala bagi penderita DM. Data profile of the Babakan Health Center, the obesity level of the population, of the 3,824 examined, 1,053 people (27%) were found to be obese. As many as 90-95% of diabetes cases are type 2 DM, most of which can be prevented because they are caused by an unhealthy lifestyle. The purpose of this service is as an effort to help control blood sugar levels of hyperglycemia sufferers with the traditional ingredients of the Sasak tribe, Songgak. As many as 45 people who attended the socialization activity had their blood glucose levels checked, as many as 14 people had blood sugar levels when ≥200mg/dl. Songgak was socialized and presented the results of research on the benefits of Songgak for lowering blood glucose levels. After consuming Songgak for two weeks, there was a temporary decrease in blood glucose levels in 21 participants. The community understands the importance of maintaining a lifestyle and the importance of regular blood glucose checks for people with DM.
The Effect of Roasting Methods of Ingredients The Songgak Tribe Sasak Herbal on Active Compounds Using Gas Chromatography Mas Spectroscopy (Gc-Ms) Analysis) Agrijanti, Agrijanti; Kusuma Dewi, Lale Budi; Khusuma, Ari; Wardoyo, Eustachius Hagni
Jurnal Kesehatan Prima Vol. 18 No. 2 (2024): AUGUST
Publisher : poltekkes kemenkes mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jkp.v18i2.1540

Abstract

Songgak is a concoction of the Sasak tribe of Lombok in West Nusa Tenggara. It consists of coffee mixed with groundwood, cloves, black pepper, coriander, and nutmeg. The original recipe involves roasting the spices before mixing them with coffee, namely using a frying pan over a stove. The roasting process is carried out without controlling the temperature and roasting time, so the roasted ingredients need to be standardized(Dewi et  al., 2021). GCMS is a tool used to analyze compounds in samples using chemical separation methods, mainly chromatography. The compounds in the mixture are separated in a chromatographic column. The separation mechanism between several compounds occurs due to differences in the solubility values of each in the moving solvent and differences in the absorption of each of the competing compounds into the stationary phase (Gross, 2017). In this research, variations will be carried out on spices, namely T1 original treatment of roasting spices over fire for 8 minutes, T2 drying spices in sunlight, T3 oven for 5 minutes, T5 oven for 5 minutes, T4 oven for 15 minutes and T5 oven for 15 minutes. In the T4 treatment, namely oven for 10 minutes, the results of the analysis of the substance content with the most types, namely 20 types, were obtained. The active anti-microbial compound found in all treatments was Hexadecanoic acid, 2-hydroxy-1-(h)(C19 H38 O4) BM:330, which helps inhibit the growth of cancer cells. (National Library Medicine, n.d.). Octadecanoic acid (CAS) Stear (C18 H34 O2) BM:282 Anti-inflammatory, Antiandrogenic Cancer prevention, Hypocholesterolemia Dermatigenic, 5-Alpha reductase inhibitor, Anemiagenic, Insecticide (Natarajan et al., 2019) and Tetradecanoic acid (CAS) Myris (C14 H28 O2) BM:228 as anti-inflammatory and anti-nociceptive. 
Pengaruh Jumlah Mengonsumsi Kopi Pada Pasien Osteoporosis Terhadap Kadar Kalsium Urin Khairal Yasmin; Lale Budi Kusuma Dewi; Ida Bagus Rai Wiadnya; I Wayan Getas
Journal of Indonesia Laboratory Students (JILTS) Vol. 5 No. 1 (2026): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v5i1.406

Abstract

Latar belakang: Osteoporosis ditandai dengan penurunan massa tulang dan peningkatan risiko patahtulang. Konsumsi kopi dapat meningkatkan ekskresi kalsium urin sehingga berpotensi memperburukkondisi osteoporosis. Penelitian ini bertujuan menganalisis pengaruh jumlah konsumsi kopi terhadap kadar kalsium urin pada pasien osteoporosis. Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh jumlah mengonsumsi kopi pada pasienosteoporosis terhadap kadar kalsium urin. Metode Penelitian: Penelitian ini dilaksanakan di RSI Siti Hajar Mataram dan Laboratorium Kimia TLMPoltekkes Kemenkes Mataram pada Juli–September 2025. Desain penelitian adalah observasional analitik dengan pendekatan cross-sectional menggunakan sampel jenuh pada seluruh pasien osteoporosis peminum kopi. Variabel bebas adalah jumlah konsumsi kopi, sedangkan variabel terikat adalah kadar kalsium urin yang diperiksa dengan metode titrasi kompleksometri. Data dianalisis menggunakan uji ANOVA atau Kruskal-Wallis sesuai distribusi data. Hasil Penelitian: Rerata kadar kalsium urin pasien yang mengonsumsi 1 gelas per hari berada pada kisaran 212.5 mg/24 jam, kelompok 2 gelas per hari 322 mg/24 jam, dan kelompok 3 gelas per hari 444.8 mg/24 jam. Berdasarkan hasil analisis menggunakan uji One-Way ANOVA, ditemukan bahwa terdapat perbedaan yang signifikan pada kadar kalsium urin antara kelompok yang mengonsumsi 1, 2, dan 3 gelas kopi per hari. Kesimpulan: Penelitian ini menunjukkan bahwa semakin tinggi jumlah konsumsi kopi, kadar kalsium urin pada penderita osteoporosis cenderung meningkat. Hal ini menegaskan bahwa konsumsi kopi berpengaruh terhadap ekskresi kalsium, sehingga perlu diperhatikan dalam upaya pencegahan dan penatalaksanaan osteoporosis.
Odds Ratio of Increase in Hemoglobin Level Associated with Consumption of Songgak Coffee in Patients with Pulmonary TB Lale Budi Kusuma Dewi; Sri Hartuti; I Wayan Getas; Agrijanti Agrijanti; Erlin Yustin Tatontos; Ida Bagus Rai Wiadnya; Siti Zaetun; Ari Khusuma
Jurnal Kefarmasian Indonesia VOLUME 15, NUMBER 1, FEBRUARY 2025
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pulmonary TB cases in Indonesia are the second highest in the world. The incidence of Anemia in pulmonary TB patients can be as high as 90%. Anemia can lead to poor outcomes in the recovery of pulmonary TB. Songgak coffee is a coffee with a mixture of spices that is commonly consumed by the people of Central Lombok to make the body healthy and increase vitality, including pulmonary TB patients. Songgak coffee is made from 7 types of spices mixed with coffee. The results of previous research show that Songgak coffee has quite good antioxidant content and is an immunostimulant. Antioxidants may increase Hemoglobin levels. This was a case-control study. A total of 26 new pulmonary TB patients were divided into 2 groups. Group A received songgak coffee as an additional anti-TB drug, while group B received anti-TB drug therapy alone. Hemoglobin levels in groups A and B were measured before drug administration and 14 days after treatment. The data collected were nominal data, reported as increasing and non-increasing. A total of 12 out of 13 patients in group A had an increase in Hemoglobin, while only 1 person in group B had an increase in Hemoglobin. The odds ratio value for increasing Hemoglobin levels in pulmonary TB patients who consume songgak is 12. The odds ratio value for increasing Hemoglobin in pulmonary TB patients taking songgak is 12. The odds ratio value for increasing Hemoglobin levels in pulmonary TB patients who take Songgak is 12 times higher than in pulmonary TB patients who do not take Songgak.
THE EFFECT OF CHEMOTHERAPY ON BLOOD CELL COUNTS IN POST-MASTECTOMY BREAST CANCER PATIENTS Muhammad Haerunnizam; Pancawati Ariami; Thomas Tandi Manu; Lale Budi Kusuma Dewi
Meditory : The Journal of Medical Laboratory Vol. 13 No. 2 (2025): Meditory, Volume 13 No. 2 Tahun 2025
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/meditory.v13i2.4096

Abstract

Background: Post-mastectomy chemotherapy often causes myelosuppression, as do the numbers of erythrocytes, leukocytes, and platelets.Objective: To determine the effect of chemotherapy on the number of blood cells in post-mastectomy breast cancer patients.Methods: This study was a retrospective observational study. The population in the study was breast cancer patients who underwent chemotherapy  0 (Pre-chemotherapy) to 4 times after mastectomy at the NTB Provincial Hospital from January to December 2024. Sampling was done using non-probability sampling with a purposive sampling method, resulting in 68 samples.Results: In the study, the average number of erythrocytes from session 0 (Pre-chemotherapy) to session 4 was 4,23; 3,80; 3,67; 3,59, and 3,6 million cells/µL. Then, the average number of leukocytes from session 0 (Pre-chemotherapy) to session 4 was 7,208; 5,024; 4,739; 3,690, and 3,281 thousand cells/µL. Meanwhile, the average number of platelets from session 0 (Pre-chemotherapy) to session 4 was 386,251; 302,792; 275,760; 228,014, and 206,035 thousand cells/µL. Based on the Friedman test data analysis, the results showed a significance value of 0.001 < 0.05.Conclusions: There is an effect of chemotherapy on the number of blood cells in post-mastectomy breast cancer patients.
Co-Authors Agrijanti, Agrijanti Aqila Fadia Ari Khusuma Awan Dramawan Baiq Linda Rolian ocatari Erlin Yustin Tatontos Eustachius Hagni Wardoyo Fadhilah Rizkiyah Fakhmi, Shausan Nabila Fihiruddin, Fihiruddin Fitri Gunarti Gunarti I Gusti Ayu Ratih Yuliartini Ayu I Made Suardika I Wayan Getas I Wayan Getas I Wayan Getas I Wayan Getas Intan Suryawatie Yomo, Meidiana Iswari Pauzi Iswari Pauzi Khairal Yasmin Lalu Sri Gede Lalu Srigede Lalu Srigede Lalu Srigede Lalu Srigede, Lalu Lidia Febrianisa Maruni Wiwin Diarti Maruni Wiwin Diarti Meidiana Intan Suryawatie Yomo Muhammad Haerunnizam Muhammad Luthfi Nandini, Ni Kadek Ni Kadek Defyantari Ni Luh P. Sri Ayu Sutami D Ni Luh Putu Pebrita Nurul Inayati Nurul Inayati Nurul Inayati Nurul Inayati Pancawati Ariami Pancawati Ariami Permatasari, Lina Pramoswari, Dining RAI WIADNYA, IDA BAGUS Rohmi Rohmi, Rohmi Safitri, Wiwin Safitri, Wiwin Siti Karyani Siti Zaetun Siti Zaetun Siti zaetun Siti Zaetun Siti Zaetun Siti Zaetun, Siti Sri Hartuti Suaryana, I Made Chandra Thomas Tandi Manu Thomas Tandi Manu Vani Nurcahyanti Viefa Avrilian Alifah Wadnya, Ida Bagus Rai Wayan Getas Wiwin Safitri Wulandari, Ayu Nurislami Yudha Anggit Jiwantoro Yunan Jiwintarum Zaenal Fikri Ziana Dia Ningsih