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All Journal Indonesian Journal of Pharmaceutical Science and Technology Jurnal Ilmu Kefarmasian Indonesia Pharmacoscript Science Midwifery Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Jurnal Abdimas Kartika Wijayakusuma Medical Sains : Jurnal Ilmiah Kefarmasian Public Health and Safety International Journal (PHASIJ) Sciences of Pharmacy Jurnal Farmasi Indonesia Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Ardhi: Jurnal Pengabdian dalam Negri Jurnal Kesehatan Bakti Tunas Husada Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Ekspresi: Publikasi Kegiatan Pengabdian Indonesia International Journal of Health and Medicine Jurnal Farmasi Galenika Sasambo: Jurnal Abdimas (Journal of Community Service)
Jajang Japar Sodik
Faculty Of Pharmacy, Universitas Bhakti Kencana
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Engineering Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Science Midwifery

 1 
Evaluation of antihypertensive drug use in preeclampsia and eclampsia patients in the inpatient room of Bandung Regency Hospital Sutrisno, Entris; Selifiana , Nita; Sodik , Jajang Japar; Agustin, Ia Nurfauziah
Science Midwifery Vol 12 No 4 (2024): October: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v12i4.1703

Abstract

Indonesia is one of the third highest developing countries in ASEAN with maternal mortality rate (MMR) and infant mortality rate (IMR). One of the three main causes of pregnancy-related maternal deaths is hypertension during pregnancy. It is very important to get rational antihypertensive therapy immediately in order to maintain normal blood pressure. This study aims to determine the profile of the use and rational use of antihypertensive drugs in preeclampsia and eclampsia patients in the Inpatient Room of Bandung Regency Hospital. The study was conducted observational with retrospective data collection. Samples were taken by random sampling which met the inclusion criteria for the period January-December 2021. The rationality of antihypertensive drug use is based on the 2019 American College of Obstetrics and Gynecologists and PIONAS guidelines. There were 78 medical records that met the criteria. The characteristics of the majority of patients aged 21-35 years (64%) with a gestational age of 28-40 weeks (97%) and the antihypertensive drug therapy that was widely used was nifedipine (56%). The percentage of rational use of antihypertensive drugs showed the right indication (100%), the right drug (95%), the right dose (100%), and the right frequency (100%).
The role of honey, curcuma, and black cumin supplements in overcoming stunting on the adaptive immune system Sabarudin, Cecep; Hasimun, Patonah; Kusriani, Herni; Zuniarto, Ahmad Azrul; Pandanwangi, Siti; Fatmawati, Eva; Afief, Arief R.; Sodik, Jajang Japar
Science Midwifery Vol 13 No 5 (2025): Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2185

Abstract

Stunting is strongly associated with impaired immune function, as chronically malnourished children tend to have weaker immunity and are more vulnerable to infection. This study aimed to examine the effect of temulawak–black cumin herbal honey on the adaptive immune system in stunted children. A quasi-experimental one-group pre-test and post-test design was used. The findings showed that the intervention significantly increased height-for-age (TB/U) in the treatment group compared to the control group (p = 0.014). Weight-for-age (BB/U) also rose significantly within the treatment group (p = 0.013), but no significant difference was found relative to the control group (p = 0.192). The supplement significantly elevated IgM levels in the treatment group (p = 0.001), though again without a significant difference from the control (p = 0.546). CD4 concentration decreased in the treatment group (p = 0.003), but the change was not significantly different from the control (p = 0.682). In conclusion, temulawak–black cumin herbal honey can improve nutritional status and enhance adaptive immunity by increasing IgM levels, although it does not raise CD4 levels and instead slows CD4 decline. However, its effectiveness in increasing IgM and CD4 concentrations compared to controls is not significant.
The role of honey, curcuma, and black cumin supplements in overcoming stunting on the adaptive immune system Sabarudin, Cecep; Hasimun, Patonah; Kusriani, Herni; Zuniarto, Ahmad Azrul; Pandanwangi, Siti; Fatmawati, Eva; Afief, Arief R.; Sodik, Jajang Japar
Science Midwifery Vol 13 No 5 (2025): December: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i5.2185

Abstract

Stunting is strongly associated with impaired immune function, as chronically malnourished children tend to have weaker immunity and are more vulnerable to infection. This study aimed to examine the effect of temulawak–black cumin herbal honey on the adaptive immune system in stunted children. A quasi-experimental one-group pre-test and post-test design was used. The findings showed that the intervention significantly increased height-for-age (TB/U) in the treatment group compared to the control group (p = 0.014). Weight-for-age (BB/U) also rose significantly within the treatment group (p = 0.013), but no significant difference was found relative to the control group (p = 0.192). The supplement significantly elevated IgM levels in the treatment group (p = 0.001), though again without a significant difference from the control (p = 0.546). CD4 concentration decreased in the treatment group (p = 0.003), but the change was not significantly different from the control (p = 0.682). In conclusion, temulawak–black cumin herbal honey can improve nutritional status and enhance adaptive immunity by increasing IgM levels, although it does not raise CD4 levels and instead slows CD4 decline. However, its effectiveness in increasing IgM and CD4 concentrations compared to controls is not significant.
Co-Authors Adinda, Deistha Afief, Arief R. Afria Hilda Restu Agustin, Ia Nurfauziah Ajeng Pramesti Akhamad Priyadi Anbar Fatin, Mia Nisrina Ani Anggriani, Ani Aqila Fadia, Andira Arif Rubianto Aris Suhardiman Asep Kamal Sahroni Astira Kosmawati Budiana, Wempi Dadang Juanda Deden Indra Dinata Deni Iskandar Destia Tresna Prima Elvira Najwa Zain Nabawi Fajarrini, Uvika Nurul Fatmawati, Eva Fatmawati, Fenti Fenti Fatmawati Fenti Fatmawati Garnadi Jafar, Garnadi Hasimun, Patonah Helen Fitri Novianti Hilda Restu, Afria Hilman Mulyana, Hilman Ida Lisni Ika Kurnia Sukmawati Ilham Bintang, Muhamad Irfani, Abdul Mulki Isviyanti Isviyanti Lia Marliani M. Ramadhan, Saputro Maharani, Ilmi Intan Mamay M Sobandi Mamay Maulana Sobandi Marita Kaniawati Maulana Sobandi, Mamay Mia Nisrina A Mia Nisrina Anbar Fatin Muhamad Reza Pahlevi Muhamad Reza, Pahlevi Mulki Irpani, Abdul Muzaki, Yoga Adi Restu Nita Selifiana Patonah, Patonah Pratama, Reza Priyadi, Akhmad Purwaniati, Purwaniati Putriyanti, Al-fira Ratu Fania Aprilyanti Reza Pratama Reza, Pratama Riyadi, Imam Roganda Situmorang Roni, Asep Rusi Rismawanti Ruswanti, Seffi Sabarudin, Cecep Saidah Mutmainah, Siti Selifiana , Nita Selifiana, Nita Siti Nurfitria, Rizki Siti Pandanwangi TW Sukmawati, ika kurnia Sumbara Sumbara Sutrisno, Entris Wahyudi, Fikri Mourly Wahyudin Wempi Budiana Wempi Budiana Widhya Aligita Yakobus Lau De Yung Sinaga Yani Mulyani Yuli Astuti Zaelani, Diki Zaelani, Diki Ziska, Rahma Zuniarto, Ahmad Azrul