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All Journal VALENSI PHARMACON Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Klinik Indonesia JURNAL ILMIAH PERSPEKTIF Majalah Obat Tradisional KOVALEN: Jurnal Riset Kimia Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Biologi Tropis Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ CARADDE: Jurnal Pengabdian Kepada Masyarakat JIMR - Journal of Islamic Medicine Research PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Jamu Indonesia Jurnal Mandala Pharmacon Indonesia Lentera Acitya Journal Of Health Majalah Farmasetika Indian Journal of Forensic Medicine & Toxicology Yumary: Jurnal Pengabdian kepada Masyarakat Prima Abdika: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Kepada Masyarakat Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat Proceeding of Mulawarman Pharmaceuticals Conferences Jurnal Farmasi Sains dan Praktis Jurnal Sains dan Teknologi Farmasi Indonesia Jurnal Kesehatan Lentera Acitya Journal of Public Health and Pharmacy Jurnal Pengabdian Farmasi dan Sains Jurnal Akademika Kimia Journal of Tropical Pharmacy and Chemistry Jurnal Sains dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Indonesian Journal of Jamu Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran
Joni Tandi, Joni
Program Studi S1 Farmasi, Sekolah Tinggi Ilmu Farmasi Pelita Mas Palu
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Enzymatic virgin coconut oil effect on urea and creatinine levels of hypercholesterolemia-diabetics induced Wistar male rats Dewi, Niluh Puspita; Alaydrus, Syafika; Nadila, Nadila; Magfirah, Magfirah; Tandi, Joni; Anggi, Viani; Astria, Nani
Pharmaciana Vol. 14 No. 1 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i1.27489

Abstract

Coconut (Cocos nucifera) is an Indonesian commodity that has high economic value tall. Virgin Coconut Oil (VCO) is one of the processed coconut products whose selling value is very high, because The composition of VCO consists of medium-chain fatty acids that can maintain a healthy body and prevent various diseases. The process of making VCO used in This research is an enzymatic method using pineapple weevil as a bromelain enzyme. This study aims to determine the effect of enzymatic administration of VCO and an enzymatic dose of VCO which is effective in reducing urea and creatinine levels in hypercholesterolemic-diabetic male white rats (Rattus norvegicus). This study was an experimental laboratory with a modified pretest and posttest randomized controlled group design using 30 test animals which were divided into 6 treatment groups. Each group consisted of 5 test animals, namely normal control, negative control, and positive control, with doses of 0.2, 0.4, and 0.8 mL/kg BW. The data obtained were analyzed using a One Way Anova and non- parametric statistical test by Kruskal Wallis. test and followed by a further Mann Whitney test to determine differences between treatments. The results showed that enzymatic VCO at a dose of 0.8 mL/kg BW was an effective dose in reducing urea and creatinine levels with an average decrease of 17.40 mg/dL and 0.36 mg/dL. The novelty in this study showed that the enzymatic VCO had an effect on reducing urea and creatinine levels in diabetic hypercholesterolemic male white rats.
Edukasi Pemanfaatan Gedi Merah Sebagai Obat Dislipidemia Handayani, Tien Wahyu; Tandi, Joni; Alaydus, Syafika; Rajadenda, Afwa Al; Sujati, Ni Wayan
Prima Abdika: Jurnal Pengabdian Masyarakat Vol. 4 No. 2 (2024): Volume 4 Nomor 2 Tahun 2024
Publisher : Program Studi Pendidikan Guru Sekolah Dasar Universitas Flores Ende

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37478/abdika.v4i2.3702

Abstract

Indonesia has 143 million hectares of tropical forest which grows 80% of the world's medicinal plants. It is estimated that 25 thousand to 30 thousand plants can be used as medicine. One of these plants is red gedi or Abelmoschus manihot. Apart from having a delicious taste, red gedi leaves also contain many polyphenols, flavonoids, tannins, vitamin A, iron, fiber, folic acid, petroleum, methanol, collagen, vitamin C and several other nutrients which can be useful as a medicine for dyslipedemia. This activity aims to educate the community in Sejahtera Village, Palolo District, Sigi Regency about the use of red gedi as a medicine for dyslipidemia. This service uses lecture methods and distributing brochures. Presentation of the level of public understanding of the benefits of red gedi is 96%, public understanding of dyslipidemia is 95%, and people's skills in processing red gedi into food and drinks that are good for health are 100%.
Edukasi Pemanfaatan Gedi Merah untuk Mengatasi Komplikasi Diabetes Tandi, Joni; Handayani, Tien Wahyu; Aril, Moh; Polakitan, Grace Lovita
Prima Abdika: Jurnal Pengabdian Masyarakat Vol. 5 No. 1 (2025): Volume 5 Nomor 1 Tahun 2025 (Maret)
Publisher : Program Studi Pendidikan Guru Sekolah Dasar Universitas Flores Ende

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37478/abdika.v5i1.5002

Abstract

Diabetes mellitus has become a serious health problem in Powelua Village with a prevalence of more than 15% of the adult population, accompanied by complications in vital organs and a high economic burden because the cost of treatment reaches IDR 1.5 million per month per patient. The community service program was implemented through comprehensive education on the use of red gedi to overcome diabetes complications, using lecture methods, interactive discussions, and practical demonstrations. Program evaluation was conducted through questionnaires distributed to 61 participants to measure the level of satisfaction and understanding. The evaluation results showed that the level of participant satisfaction reached an average of 84% (very good category), with three indicators reaching the very good category (80-100%) including the method of delivering material (100%), ease of understanding the material (100%), and the ability of the presenter to answer questions (80%). This program has succeeded in increasing community understanding of the use of red gedi as a safe and affordable alternative treatment for diabetes, although program adjustments are still needed to meet community expectations in future activities.
Edukasi Mengenai Pencegahan dan Pengobatan Schistosomiasis di Desa Dodolo Lore Utara Handayani, Tien Wahyu; Tandi, Joni; Putri, Debby Aulia; Ticoh, Febriyani; Rusdi, Grasela; Uigianto, Imelda; Ahmad, Mirnawati; Safitri, Nabila Umi
Prima Abdika: Jurnal Pengabdian Masyarakat Vol. 5 No. 3 (2025): Volume 5 Nomor 3 Tahun 2025
Publisher : Program Studi Pendidikan Guru Sekolah Dasar Universitas Flores Ende

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37478/abdika.v5i3.5942

Abstract

Schistosomiasis is an infectious parasitic disease caused by the Schistosoma worm, transmitted by the snail Oncomelania hupensis lindoensis in endemic areas such as Dodolo Village, Poso Regency, Central Sulawesi. This village has the highest number of intermediate snail foci in the Napu highlands, making it a strategic location for educational interventions. This community service activity aims to improve community knowledge, attitudes, and behavior related to the prevention and treatment of schistosomiasis. Education was carried out using interactive lecture methods, discussions, and pre-test and post-test evaluations of 34 participants from various levels of society. The results showed an increase in the average knowledge score from 3.76 (37.6%) in the pre-test to 8.00 (80.0%) in the post-test, with increased participation and overall understanding. This activity succeeded in building collective awareness and understanding that was evenly distributed throughout the community, and was responded to with a high level of satisfaction (92%). It can be concluded that the participatory education approach is effective in increasing the capacity of the Dodolo Village community in controlling schistosomiasis and can be replicated in other endemic areas as part of a national elimination strategy.
PEMANFAATAN TUMBUHAN SEBAGAI OBAT DIABETES MELLITUS DI DESA LAMPO, KEC. BANAWA, KAB. DONGGALA Tandi, Joni; Toding, Ficanata Adhiguna; Riani, Ni Putu Intan; Dewi, Alfia
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 2 No. 1 (2023): Oktober 2023
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2023.v2.i1.16421

Abstract

Obat tradisional adalah bahan atau ramuan berbahan tumbuhan, hewan, mineral, sediaan sarian (galenik), atau campuran dari bahan tersebut yang secara turun temurun telah digunakan untuk pengobatan. Penggunaan obat tradisional ini di era moderinisasi ini diperkuat oleh riset-riset yang ada dengan data yang kompelementer membuat masyarakat lebih memilih pengobatan dengan menggunakan bahan-bahan alami. Diabetes merupakan penyakit yang tidak asing dalam kehidupan kita sehari-hari yang dapat diobati menggunakan obat-obatan dari tumbuhan. Diabetes merupakan masalah kesehatan yang banyak menarik perhatian karena angka prevalensi yang bertambah setiap tahunnya, terutama di negara berkembang seperti di Indonesia. , sehingga perlu adanya edukasi pemanfaatan tumbuhan obat diabetes mellitus di masyarakat desa Lampo. Edukasi melalui penyuluhan dengan metode ceramah interaktif. Efektivitas penyuluhan ini dapat diuji dengan pemberian kuisiner kepuasan mitra terhadap kegiatan yang dilaksanakan. Hasil pengamatan kegiatan menunjukkan 95% mitra merasa puas dengan edukasi tersebut.
Determination of Secondary Metabolites and Antioxidant Activity of Robusta Coffee Bean Ethanol Extract by UV-Vis Spectrophotometry Tandi, Joni; Riani, Ni P. I.; Handayani, Tien W.; Kanan, Maria
Jurnal Akademika Kimia Vol. 12 No. 1 (2023)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24775185.2023.v12.i1.pp58-64

Abstract

Robusta coffee beans (Coffea canephora Pierre ex.A.Froehner) have antioxidant, antidiabetic, and antihypertensive effects and can prevent coronary heart disease. This study aims to determine the compound content and total levels of secondary metabolites and to determine the antioxidant activity of robusta coffee bean extract. UV-Vis spectrophotometer was used to determine the total levels of secondary metabolites and antioxidant assay using DPPH reagent. The results obtained for the positive qualitative test contain secondary metabolites of alkaloids, flavonoids, saponins, and tannins and do not contain steroid compounds while for the quantitative test, the total alkaloid content is 0.1973% w/w (caffeine equivalent), flavonoids are 1.2106% w/w (equivalent to quercetin), saponins 0.536% w/w (equivalent to sapogenins), tannins at 9.7103% w/w (equivalent to tannic acid). The IC50 result for the antioxidant activity of the ethanolic extract of robusta coffee beans is 55.16 µg/mL which is included in the category of strong antioxidants.
Optimalisasi Potensi Tanaman Herbal Lokal Melalui Pelatihan Pembuatan Minyak Gosok di Desa Petiro, Kabupaten Poso Joni Tandi; Tien Wahyu Handayani; Vivi Gretia Triposa
PaKMas: Jurnal Pengabdian Kepada Masyarakat Vol 5 No 2 (2025): November 2025
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/pakmas.v5i2.4075

Abstract

The use of herbal plants in modern medicine is increasing, notably for their antioxidant properties that effectively reduce free radicals. The growing "back to nature" trend, coupled with the high cost of modern pharmaceuticals, has encouraged communities to seek safer alternative treatments. This community service program was designed to enhance the capabilities of residents in Petiro Village, East Pamona District, Poso Regency to independently produce herbal massage oil as a sustainable health solution. Methodologically, the program employed a combination of lectures, practical demonstrations, and interactive discussions. Evaluation was conducted through pre-tests and post-tests administered to 22 participants to measure knowledge acquisition. The implementation process followed a systematic approach: preparation of raw materials, processing them into dry simplicia, and formulating massage oil using essential oils combined with natural herbs including ginger, turmeric, red betel leaf, garlic, and onion. Results demonstrated a remarkable improvement in community understanding, rising from 25% to 100% following the training intervention. This improvement encompassed comprehensive knowledge of the benefits, production techniques, and understanding of herbal massage oil ingredients. The training successfully fostered practical skills that participants could immediately apply. The significant knowledge transfer achieved has important implications for developing local herbal massage oil production as a sustainable enterprise, potentially improving both community health outcomes and economic prosperity in rural communities. Additionally, this initiative contributes to preserving traditional herbal knowledge while adapting it to contemporary health needs, creating a viable model for other rural communities seeking health self-sufficiency.
Innovative Oil from STIFA Pelita Mas for Glycemic Control and Tissue Regeneration in Diabetic Rats Joni Tandi; Muthmainah Tuldjanah; Tien Wahyu Handayani
Journal of Public Health and Pharmacy Vol. 6 No. 1 (2026): March 2026
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v6i1.7192

Abstract

Introduction: Diabetes mellitus is a significant global health problem with increasing prevalence in Indonesia. Conventional management of diabetes mellitus is often accompanied by side effects and high costs, prompting the search for alternatives based on natural ingredients. STIFA Pelita Mas Herbal Oil is an innovative formulation that combines various efficacious natural ingredients, but its effectiveness on histopathological changes in pancreatic and kidney tissues due to diabetes has not been comprehensively explored. This study aims to evaluate the effectiveness and mechanism of action of STIFA Pelita Mas Herbal Oil on reducing blood glucose levels, repairing pancreatic tissue damage, and kidneys in a streptozotocin-induced rat model. Methods: This study used a quantitative approach with an experimental design on 30 male white rats (Rattus norvegicus) divided into 6 treatment groups. STIFA Pelita Mas Herbal Oil is made by combining simplicia (Shallots, Garlic, Ginger, Curcuma zanthorrhiza, Lemongrass red, and Piper ornatum leaves) with various oils (VCO, eucalyptus oil, citronella oil, olive oil, and cinnamomum cullilawan). Diabetes was induced using streptozotocin (40 mg/kg BW) intraperitoneally. The parameters measured included blood glucose levels and histopathological changes in the kidneys and pancreas with Hematoxylin-Eosin staining. Data were analyzed using One Way ANOVA followed by the LSD or Kruskal-Wallis test. Result: The results showed that all three herbal oil formulas were able to lower blood glucose levels, with formula 1 and formula 3 showing comparable effectiveness to glibenclamide on day 28. In histopathological observations of the kidneys, formula 3 showed the best effectiveness in repairing damage to renal tubule and glomerular cells with a damage score of 0, equivalent to normal controls. Similarly, in histopathological observations of the pancreas, formula 3 showed the highest effectiveness in repairing damage to pancreatic beta cells with a damage score of 0.2, not significantly different from normal and positive controls. Conclusion: Stifa Pelita Mas herbal oil, especially formula 3, has the potential as an effective antidiabetic agent in lowering blood glucose levels and repairing tissue damage in the kidneys and pancreas due to diabetes. Future research should focus on dose variations to see at what dose this oil is effective.
Edukasi Pengobatan Tradisional Dan Modern Schistosomiasis Di Desa Langko, Kecamatan Lindu Tandi, Joni; Handayani, Tien Wahyu; Arynesta, Teddy; Andini, Tuti Allawiah; Insani, Nabila Nurul; Gintu, Tri Juniver
Yumary: Jurnal Pengabdian kepada Masyarakat Vol. 6 No. 2 (2025): Desember
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/yumary.v6i2.3339

Abstract

Purpose: To provide new knowledge to the Langko Village community about schistosomiasis, which can be treated with synthetic drugs such as praziquantel and anthelmintics, and traditional medicine using betel nuts. Methodology/approach: The PKM activity in Langko Village was carried out in three stages, namely preparation including a location survey to obtain permission from local government officials and prepare the necessary facilities and infrastructure needed during the activity, the second stage is providing education through lectures and material brochures, discussions, and measuring the level of community satisfaction with the activities carried out through activity evaluation by distributing questionnaires, and the third stage is distributing assistance to the community present in the form of basic necessities. Results: The community was very satisfied with this educational activity, with an average satisfaction value of 98% from six satisfaction assessment indicators. Conclusions: The community health education program successfully enhanced local knowledge of schistosomiasis treatment options, demonstrating high community acceptance of both conventional pharmaceutical interventions and traditional betel nut therapy. Limitations: The limitations of this PKM activity have not been able to reach all the snail focus areas because road access is still damaged. Contribution: This PKM has significant implications for public health in Langko Village, where partners feel helped by the new knowledge, namely, betel nut as a medicine for schistosomiasis, which is far from side effects compared to chemical drugs.
POTENSI ANTIDIABETIK EKSTRAK ETANOL DAUN MATOA(Pometia pinnata) PADA TIKUS PUTIH JANTAN Joni Tandi; Afriani S; Nadira; Handayani KR; Wirawan W; Afrizal; Tien Wahyu Handayani
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 1 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i1.521

Abstract

Diabetes Mellitus is a metabolic disease characterized by high blood glucose levels which is commonly called hyperglycemia due to lack of insulin secretion. One of the matoa plants (Pometia pinnata) that has been used as a traditional medicine is matoa leaves which are efficacious as diabetes mellitus. The purpose of this study was to determine the secondary metabolite compounds in the ethanol extract of matoa leaves, as well as to determine the potential dose of ethanolic extract of matoa leaves which was effective in reducing blood glucose levels and on the histopathological description of the pancreas of male white rats induced by Streptozotocin. This study used a laboratory experimental method, divided into 6 treatment groups, each group consisting of 5 rats, namely normal control, negative control, positive control, treatment groups with doses of 100, 200, and 300 mg/kg body weight. Data were analyzed using One Way ANOVA statistical test at 95% confidence level followed by LSD test to see differences between treatments. The results showed that the ethanolic extract of matoa leaves contained secondary metabolites of alkaloids, flavonoids, saponins, tannins, and steroids. at a dose of 300 mg/kg BW showed effective results in reducing blood glucose levels with an average decrease of 99.6 mg/dL and the ethanol extract of matoa leaves had the potential to regenerate pancreatic cells in streptozotocin-induced male white rats of 0. 6±0.54
Co-Authors Afriani S Afrizal Agustinus Widodo Ahmad, Mirnawati Alaydrus, Syafika Alaydus, Syafika Andini, Tuti Allawiah Anita Purwantari Aril, Moh Arynesta, Teddy Asrifa Asrifa Astria, Nani Astuti, Dewi Qurrotul Ayu Martina Ayu Wuladari Ayu Wulandari Ayu Wulandari AYU WULANDARI Azwaajum Mutahharah Basilingan, Aprince Bella Melinda Cinda Pradita Sudar Claresta, Jong A. Darmayanti David Pakaya David Pakaya Debora Rislianti Lakiu Dewi Astuti Dewi, Alfia Dhitania Ivana Harliwong Dian S. Waruwu Diana Pratiwi, Franciska Erdy Prasetyo Fahruddin Fahruddin Faisal Rahmat Nugraha Fajar Alan Feiverin Tibe Gabriella Bamba Ratih Lintin Gintu, Tri Juniver Gusti Ayu Gusti Ayu, Gusti Handayani KR Handayani, Kiki Rizki Handayani, Tien W. Handayani, Tien Wahyu Handayani, Tien Wahyuni Hastuti L I Made Dipayana Ida Yanti Palinggi Insani, Nabila Nurul Irwan Irwan Islamiati, Utami Jong A. Claresta Kurnia Gatot Novrianto L, Wahyudin H Lakiu, Debora Rislianti Lexy Kareba Lidongi, Putri Marcelita Lina Hardianti Rukmana M, Yulan Magfira Magfira Magfirah Magfirah, Magfirah Magfiroh Magfiroh Maria Kanan Mariyani Mariyani, Mariyani Marsella, Mimi Marzela Dewi Meike Rachmawati Moh Rizky Moh. Roem Muaadzatul Izzah Sudarman Muhammad Agus Muljanto Muthi’ah H Z Muthmainah Tuldjanah Muthmainah Tuldjanah Na'i, Alpina Nadila Nadila Nadila, Nadila Nadira Nani Astria Ni Made Irma Mariani Ni Putu Setiawati Ni Wayan Ika Purwasih Niluh Puspita Dewi Niluh Puspita Dewi Niluh Puspita Dewi Niluh Puspita Dewi, Niluh Puspita Niswatulfahriyati Niswatulfahriyati Novalia Merue Nur Azizah Nur Ikhwan Nurhikmah Nurhikmah Nurmadinah Nurmadinah Nurul Ulzmi Ovan Nugroho Pegia Parobe, Alda Iglesias Pasang, Sisilia Baan Polakitan, Grace Lovita Puspita Dewi, Niluh Putri Natalia Laurenza Ladjeba Putri, Debby Aulia Putu Intan R, Yana Novika Rahmawati D Rajadenda, Afwa Al Rasmiyanti, Ni Kadek Evy Recky Patala Rezky Yanuarty Rezky Yanuarty Riani, Ni P. I. Riani, Ni Putu Intan Rio Mariani Risna Yanti Rivani Tampang Rizaldy Lalu Ronaldy Nobertson Rusdi, Grasela Ruterlin, Valen Safitri, Nabila Umi Salsabila, Unik Hanifah Sasdila, Sasdila Seblin Tonapa Rammang Solehah, Puput Octaviani Sri Mulyani Sri Mulyani Sri Mulyani Sri Mulyani Sabang Sririzqi Muthmainnah Stely Gracia Bengkati Suarsana, I Made Agus Sujati, Ni Wayan Surat, Megawati R. surisna, surisna Syafika Alaydrus Syafika Alaydrus Tamunu, Jeine Sweet Natasya Tandy, Putri Adam Tarusu, Fikhta Agnesya Tiara Anastasya Ticoh, Febriyani Tien Wahyu Handayani Tien Wahyu Handayani Tien Wahyu Handayani Tien Wahyu Handayani Tien Wahyu Handayani Tien Wahyu Handayani Tien, Tien Wahyu Handayani Toding, Ficanata Adhiguna Tonapa Rammang, Seblin Towulu, Dessy Gracelia Tuldjanah, Muthmainah Uigianto, Imelda Utami Islamiati Utami, Indah Kurnia Valen Ruterlin Veronika Veronika Viani Anggi Vidya Christin Vivi Gretia Triposa Wahyu Handayani, Tien Wahyu Nur Afandi WAYAN WAYAN Wayan Wirawan Wirawan W Wirawan, Resky Chandra Yana Novika R Yanti Palinggi, Ida Yanuarty, Rezky Yasinta Rakanita Yuli Fitriana Yuliet Yuliet Yulistien Yusuf Yunlis Silintowe Kenta Yusriadi Yusriadi Yustin Yustin Zulfaidah