Claim Missing Document
Check
Articles

Edukasi Mengenai Pencegahan dan Pengobatan Schistosomiasis di Desa Dodolo Lore Utara Handayani, Tien Wahyu; Tandi, Joni; Putri, Debby Aulia; Ticoh, Febriyani; Rusdi, Grasela; Uigianto, Imelda; Ahmad, Mirnawati; Safitri, Nabila Umi
Prima Abdika: Jurnal Pengabdian Masyarakat Vol. 5 No. 3 (2025): Volume 5 Nomor 3 Tahun 2025
Publisher : Program Studi Pendidikan Guru Sekolah Dasar Universitas Flores Ende

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37478/abdika.v5i3.5942

Abstract

Schistosomiasis is an infectious parasitic disease caused by the Schistosoma worm, transmitted by the snail Oncomelania hupensis lindoensis in endemic areas such as Dodolo Village, Poso Regency, Central Sulawesi. This village has the highest number of intermediate snail foci in the Napu highlands, making it a strategic location for educational interventions. This community service activity aims to improve community knowledge, attitudes, and behavior related to the prevention and treatment of schistosomiasis. Education was carried out using interactive lecture methods, discussions, and pre-test and post-test evaluations of 34 participants from various levels of society. The results showed an increase in the average knowledge score from 3.76 (37.6%) in the pre-test to 8.00 (80.0%) in the post-test, with increased participation and overall understanding. This activity succeeded in building collective awareness and understanding that was evenly distributed throughout the community, and was responded to with a high level of satisfaction (92%). It can be concluded that the participatory education approach is effective in increasing the capacity of the Dodolo Village community in controlling schistosomiasis and can be replicated in other endemic areas as part of a national elimination strategy.
PEMANFAATAN TUMBUHAN SEBAGAI OBAT DIABETES MELLITUS DI DESA LAMPO, KEC. BANAWA, KAB. DONGGALA Tandi, Joni; Toding, Ficanata Adhiguna; Riani, Ni Putu Intan; Dewi, Alfia
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 2 No. 1 (2023): Oktober 2023
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2023.v2.i1.16421

Abstract

Obat tradisional adalah bahan atau ramuan berbahan tumbuhan, hewan, mineral, sediaan sarian (galenik), atau campuran dari bahan tersebut yang secara turun temurun telah digunakan untuk pengobatan. Penggunaan obat tradisional ini di era moderinisasi ini diperkuat oleh riset-riset yang ada dengan data yang kompelementer membuat masyarakat lebih memilih pengobatan dengan menggunakan bahan-bahan alami. Diabetes merupakan penyakit yang tidak asing dalam kehidupan kita sehari-hari yang dapat diobati menggunakan obat-obatan dari tumbuhan. Diabetes merupakan masalah kesehatan yang banyak menarik perhatian karena angka prevalensi yang bertambah setiap tahunnya, terutama di negara berkembang seperti di Indonesia. , sehingga perlu adanya edukasi pemanfaatan tumbuhan obat diabetes mellitus di masyarakat desa Lampo. Edukasi melalui penyuluhan dengan metode ceramah interaktif. Efektivitas penyuluhan ini dapat diuji dengan pemberian kuisiner kepuasan mitra terhadap kegiatan yang dilaksanakan. Hasil pengamatan kegiatan menunjukkan 95% mitra merasa puas dengan edukasi tersebut.
Determination of Secondary Metabolites and Antioxidant Activity of Robusta Coffee Bean Ethanol Extract by UV-Vis Spectrophotometry Tandi, Joni; Riani, Ni P. I.; Handayani, Tien W.; Kanan, Maria
Jurnal Akademika Kimia Vol. 12 No. 1 (2023)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24775185.2023.v12.i1.pp58-64

Abstract

Robusta coffee beans (Coffea canephora Pierre ex.A.Froehner) have antioxidant, antidiabetic, and antihypertensive effects and can prevent coronary heart disease. This study aims to determine the compound content and total levels of secondary metabolites and to determine the antioxidant activity of robusta coffee bean extract. UV-Vis spectrophotometer was used to determine the total levels of secondary metabolites and antioxidant assay using DPPH reagent. The results obtained for the positive qualitative test contain secondary metabolites of alkaloids, flavonoids, saponins, and tannins and do not contain steroid compounds while for the quantitative test, the total alkaloid content is 0.1973% w/w (caffeine equivalent), flavonoids are 1.2106% w/w (equivalent to quercetin), saponins 0.536% w/w (equivalent to sapogenins), tannins at 9.7103% w/w (equivalent to tannic acid). The IC50 result for the antioxidant activity of the ethanolic extract of robusta coffee beans is 55.16 µg/mL which is included in the category of strong antioxidants.
Optimalisasi Potensi Tanaman Herbal Lokal Melalui Pelatihan Pembuatan Minyak Gosok di Desa Petiro, Kabupaten Poso Joni Tandi; Tien Wahyu Handayani; Vivi Gretia Triposa
PaKMas: Jurnal Pengabdian Kepada Masyarakat Vol 5 No 2 (2025): November 2025
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/pakmas.v5i2.4075

Abstract

The use of herbal plants in modern medicine is increasing, notably for their antioxidant properties that effectively reduce free radicals. The growing "back to nature" trend, coupled with the high cost of modern pharmaceuticals, has encouraged communities to seek safer alternative treatments. This community service program was designed to enhance the capabilities of residents in Petiro Village, East Pamona District, Poso Regency to independently produce herbal massage oil as a sustainable health solution. Methodologically, the program employed a combination of lectures, practical demonstrations, and interactive discussions. Evaluation was conducted through pre-tests and post-tests administered to 22 participants to measure knowledge acquisition. The implementation process followed a systematic approach: preparation of raw materials, processing them into dry simplicia, and formulating massage oil using essential oils combined with natural herbs including ginger, turmeric, red betel leaf, garlic, and onion. Results demonstrated a remarkable improvement in community understanding, rising from 25% to 100% following the training intervention. This improvement encompassed comprehensive knowledge of the benefits, production techniques, and understanding of herbal massage oil ingredients. The training successfully fostered practical skills that participants could immediately apply. The significant knowledge transfer achieved has important implications for developing local herbal massage oil production as a sustainable enterprise, potentially improving both community health outcomes and economic prosperity in rural communities. Additionally, this initiative contributes to preserving traditional herbal knowledge while adapting it to contemporary health needs, creating a viable model for other rural communities seeking health self-sufficiency.
Edukasi Pengobatan Tradisional Dan Modern Schistosomiasis Di Desa Langko, Kecamatan Lindu Tandi, Joni; Handayani, Tien Wahyu; Arynesta, Teddy; Andini, Tuti Allawiah; Insani, Nabila Nurul; Gintu, Tri Juniver
Yumary: Jurnal Pengabdian kepada Masyarakat Vol. 6 No. 2 (2025): Desember
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/yumary.v6i2.3339

Abstract

Purpose: To provide new knowledge to the Langko Village community about schistosomiasis, which can be treated with synthetic drugs such as praziquantel and anthelmintics, and traditional medicine using betel nuts. Methodology/approach: The PKM activity in Langko Village was carried out in three stages, namely preparation including a location survey to obtain permission from local government officials and prepare the necessary facilities and infrastructure needed during the activity, the second stage is providing education through lectures and material brochures, discussions, and measuring the level of community satisfaction with the activities carried out through activity evaluation by distributing questionnaires, and the third stage is distributing assistance to the community present in the form of basic necessities. Results: The community was very satisfied with this educational activity, with an average satisfaction value of 98% from six satisfaction assessment indicators. Conclusions: The community health education program successfully enhanced local knowledge of schistosomiasis treatment options, demonstrating high community acceptance of both conventional pharmaceutical interventions and traditional betel nut therapy. Limitations: The limitations of this PKM activity have not been able to reach all the snail focus areas because road access is still damaged. Contribution: This PKM has significant implications for public health in Langko Village, where partners feel helped by the new knowledge, namely, betel nut as a medicine for schistosomiasis, which is far from side effects compared to chemical drugs.
POTENSI ANTIDIABETIK EKSTRAK ETANOL DAUN MATOA(Pometia pinnata) PADA TIKUS PUTIH JANTAN Joni Tandi; Afriani S; Nadira; Handayani KR; Wirawan W; Afrizal; Tien Wahyu Handayani
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 1 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i1.521

Abstract

Diabetes Mellitus is a metabolic disease characterized by high blood glucose levels which is commonly called hyperglycemia due to lack of insulin secretion. One of the matoa plants (Pometia pinnata) that has been used as a traditional medicine is matoa leaves which are efficacious as diabetes mellitus. The purpose of this study was to determine the secondary metabolite compounds in the ethanol extract of matoa leaves, as well as to determine the potential dose of ethanolic extract of matoa leaves which was effective in reducing blood glucose levels and on the histopathological description of the pancreas of male white rats induced by Streptozotocin. This study used a laboratory experimental method, divided into 6 treatment groups, each group consisting of 5 rats, namely normal control, negative control, positive control, treatment groups with doses of 100, 200, and 300 mg/kg body weight. Data were analyzed using One Way ANOVA statistical test at 95% confidence level followed by LSD test to see differences between treatments. The results showed that the ethanolic extract of matoa leaves contained secondary metabolites of alkaloids, flavonoids, saponins, tannins, and steroids. at a dose of 300 mg/kg BW showed effective results in reducing blood glucose levels with an average decrease of 99.6 mg/dL and the ethanol extract of matoa leaves had the potential to regenerate pancreatic cells in streptozotocin-induced male white rats of 0. 6±0.54
Edukasi Pengobatan Tradisional Dan Modern Schistosomiasis Di Desa Langko, Kecamatan Lindu Tandi, Joni; Handayani, Tien Wahyu; Arynesta, Teddy; Andini, Tuti Allawiah; Insani, Nabila Nurul; Gintu, Tri Juniver
Yumary: Jurnal Pengabdian kepada Masyarakat Vol 6 No 2 (2025): Desember
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/yumary.v6i2.3339

Abstract

Purpose: To provide new knowledge to the Langko Village community about schistosomiasis, which can be treated with synthetic drugs such as praziquantel and anthelmintics, and traditional medicine using betel nuts. Methodology/approach: The PKM activity in Langko Village was carried out in three stages, namely preparation including a location survey to obtain permission from local government officials and prepare the necessary facilities and infrastructure needed during the activity, the second stage is providing education through lectures and material brochures, discussions, and measuring the level of community satisfaction with the activities carried out through activity evaluation by distributing questionnaires, and the third stage is distributing assistance to the community present in the form of basic necessities. Results: The community was very satisfied with this educational activity, with an average satisfaction value of 98% from six satisfaction assessment indicators. Conclusions: The community health education program successfully enhanced local knowledge of schistosomiasis treatment options, demonstrating high community acceptance of both conventional pharmaceutical interventions and traditional betel nut therapy. Limitations: The limitations of this PKM activity have not been able to reach all the snail focus areas because road access is still damaged. Contribution: This PKM has significant implications for public health in Langko Village, where partners feel helped by the new knowledge, namely, betel nut as a medicine for schistosomiasis, which is far from side effects compared to chemical drugs.
Acute Toxicity Nanoemultion of Ethanol Extract of Clove Leaves (Syzygium aromaticum L.) Muthmainah Tuldjanah; Putri Natalia Laurenza Ladjeba; Rezky Yanuarty; Ayu Wuladari; Joni Tandi; Muaadzatul Izzah Sudarman
Jurnal Penelitian Pendidikan IPA Vol 12 No 2 (2026)
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i2.12783

Abstract

Clove leaves have been widely used as traditional medicine. Clove leaves are rich in saponins, flavonoids, tannins, sterols, and essential oils. To improve the function of clove leaves, one of them is by reducing the sample size into nanoemulsion form. Nanoemulsions were prepared using the sonication method and exhibited an average droplet size of 13.3 nm. The purpose of this study was to determine the toxic properties, the dose that can cause toxic effects, and the LD50 value of nanoemulsion administration of ethanol extract of clove leaves. This study used 25 male white rats which were divided into five groups, namely a control group (nanoemulsion base) and four treatment groups receiving oral doses of 5, 50, 300, and 2000 mg/kg BW. The LD50 value was calculated using AOT425 StatPgm in accordance with OECD TG 425 (Up and Down Procedure). Mortality summary: control 0/5; 5 mg/kg BW 0/5; 50 mg/kg BW 0/5; 300 mg/kg BW 0/5; 2000 mg/kg BW 5/5. The results showed an LD50 of 798.5 mg/kg BW and, based on the GHS, it falls under Acute Toxicity (Oral) Category 4 (300–2000 mg/kg BW). Clinical signs such as piloerection, grooming, and weakness appeared mainly in the early observation phase (from 30 minutes to 4/8/12 hours) in each dose group and were reversible.
Subchronic Toxicity Test of Purple Leaves Ethanol Extract (PLEE) on the Histopathological Picture of the Lymph of Wistar Rats and Antioxidant Activity Darmayanti; Niluh Puspita Dewi; Mariyani; Joni Tandi; Meike Rachmawati; Yuliet Susanto
Jurnal Penelitian Pendidikan IPA Vol 10 No 7 (2024): July
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i7.8070

Abstract

This study aims to determine the toxic effects of purple leaf ethanol extract on lymph organs at doses of 500; 2.000; and 5.000 mg/kgBB administered for 28 days and and to determine the antioxidant activity of purple leaf Graptophyllum pictum (L.) This study is an experimental study with a random group design, using 20 test animals divided into 4 groups consisting of two treatment groups, namely in the normal control group given Na-CMC 0.5% and the experimental group given PLEE (k1: dose 500 mg/kgBB, k2: dose 2.000 mg/kgBB and k3: dose 5.000 mg/kgBB hematoxylin-eosin staining (HE) using a computer-connected Motic BA210 microscope with 40X magnification in 5 fields of view and antioxidant test using DPPH method with UV-Vis Spectrophotometer at 516 nm wavelength with concentration 20, 40, 60, 80, and 100 ppm. The results showed that leaf ethanol extract was toxic at a dose of 2.000 mg/kgBB – 5.000 mg/kgBB against the diameter of lymphatic organ pulp, organ index and organ weight, there were symptoms of toxicity and purple leaf ethanol extract had strong antioxidant activity with 66.26 μg/mL.
UJI TOKSISITAS SUB KRONIS EKSTRAK DAUN UNGU TERHADAP GAMBARAN HISTOPATOLOGI GINJAL TIKUS PUTIH JANTAN I Made Dipayana; Niluh Puspita Dewi; Magfira; Joni Tandi; Wayan Wirawan; Meike Rachmawati; Nur Azizah
Jurnal Penelitian Pendidikan IPA Vol 10 No 8 (2024): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i8.8312

Abstract

Traditional herbal medicine has become increasingly popular as an alternative to conventional medical treatments. Although the plant offers numerous health benefits, caution should be exercised regarding its long-term use. Long-term use of traditional herbal remedies can have detrimental effects on the kidneys. This study was designed to assess the histological changes in the kidneys of male rats following 28 days of purple sage leaf extract administration and to identify potential harmful effects. The study utilized 20 male Wistar rats and utilized a randomized group design for the experimental methodology. Rats were categorized into four distinct groups, consisting of one control group and three treatment groups. The control group received solely sodium chloride, whereas the treatment group 1 (P1) received 500 mg/kg BB of purple sage ethanol extract. Treatment group 2 received up to 2000 mg/kg BB of purple sage ethanol extract, while treatment group 3 received up to 5000 mg/kg BB. The oral examination was conducted for a duration of 28 days. The treatment groups showed an increase in weight and organ index of the right kidney. The findings suggest a potential for toxicity resulting from the administration of purple sage leaf extract over a duration of 28 days.
Co-Authors Afriani S Afrizal Agustinus Widodo Ahmad, Mirnawati Alaydrus, Syafika Alaydus, Syafika Andini, Tuti Allawiah Anita Purwantari Aril, Moh Arynesta, Teddy Asrifa Asrifa Astuti, Dewi Qurrotul Ayu Martina Ayu Wuladari Ayu Wulandari Ayu Wulandari AYU WULANDARI Azwaajum Mutahharah Basilingan, Aprince Bella Melinda Cinda Pradita Sudar Claresta, Jong A. Darmayanti David Pakaya David Pakaya Debora Rislianti Lakiu Dewi Astuti Dewi, Alfia Dhitania Ivana Harliwong Dian S. Waruwu Diana Pratiwi, Franciska Erdy Prasetyo Fahruddin Fahruddin Faisal Rahmat Nugraha Fajar Alan Feiverin Tibe Ficanata Adhiguna Toding Ficanata Adhiguna Toding Gabriella Bamba Ratih Lintin Gintu, Tri Juniver Gusti Ayu Gusti Ayu, Gusti Handayani KR Handayani, Kiki Rizki Handayani, Tien W. Handayani, Tien Wahyu Handayani, Tien Wahyuni Hastuti L I Made Dipayana Ida Yanti Palinggi Insani, Nabila Nurul Irwan Irwan Islamiati, Utami Jong A. Claresta Kurnia Gatot Novrianto L, Wahyudin H Lexy Kareba Lidongi, Putri Marcelita Lina Hardianti Rukmana M, Yulan Magfira Magfirah Magfirah, Magfirah Magfiroh Magfiroh Maria Kanan Mariyani Marsella, Mimi Marzela Dewi Matra Novalia Palipadang Meike Rachmawati Moh Rizky Moh. Roem Muaadzatul Izzah Sudarman Muhammad Agus Muljanto Muthi’ah H Z Muthmainah Tuldjanah Na'i, Alpina Nadila Nadila Nadila, Nadila Nadira Nani Astria Polontalo Ni Made Irma Mariani Ni Putu Setiawati Ni Wayan Ika Purwasih Niluh Puspita Dewi Niluh Puspita Dewi Niluh Puspita Dewi Niluh Puspita Dewi, Niluh Puspita Niswatulfahriyati Niswatulfahriyati Novalia Merue Nur Azizah Nur Ikhwan Nurhikmah Nurhikmah Nurmadinah Nurmadinah Nurul Ulzmi Ovan Nugroho Pegia Parobe, Alda Iglesias Pasang, Sisilia Baan Polakitan, Grace Lovita Puspita Dewi, Niluh Putri Natalia Laurenza Ladjeba Putri, Debby Aulia Putu Intan Rahmawati D Rajadenda, Afwa Al Rasmiyanti, Ni Kadek Evy Recky Patala Rezky Yanuarty Rezky Yanuarty Riani, Ni P. I. Riani, Ni Putu Intan Rio Mariani Risna Yanti Rivani Tampang Rizaldy Lalu Ronaldy Nobertson Rusdi, Grasela Ruterlin, Valen Safitri, Nabila Umi Salsabila, Unik Hanifah Sasdila, Sasdila Seblin Tonapa Rammang Solehah, Puput Octaviani Sri Mulyani Sri Mulyani Sri Mulyani Sri Mulyani Sabang Sririzqi Muthmainnah Stely Gracia Bengkati Suarsana, I Made Agus Sujati, Ni Wayan Surat, Megawati R. surisna, surisna Syafika Alaydrus Syafika Alaydrus Tamunu, Jeine Sweet Natasya Tarusu, Fikhta Agnesya Tiara Anastasya Ticoh, Febriyani Tien Wahyu Handayani Tien Wahyu Handayani Tien Wahyu Handayani Tien Wahyu Handayani Tien Wahyu Handayani Tien Wahyu Handayani Tien, Tien Wahyu Handayani Tonapa Rammang, Seblin Towulu, Dessy Gracelia Tuldjanah, Muthmainah Uigianto, Imelda Utami Islamiati Utami, Indah Kurnia Valen Ruterlin Veronika Veronika Vianda Managanta Viani Anggi Vidya Christin Vivi Gretia Triposa Wahyu Handayani, Tien Wahyu Nur Afandi WAYAN WAYAN Wayan Wirawan Wirawan W Wirawan, Resky Chandra Yana Novika R Yanti Palinggi, Ida Yanuarty, Rezky Yasinta Rakanita Yuli Fitriana Yuliet Yuliet Yulistien Yusuf Yunlis Silintowe Kenta Yusriadi Yusriadi Yustin Yustin Zulfaidah