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All Journal VALENSI Jurnal Farmasi Udayana PHARMACON Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Klinik Indonesia JURNAL ILMIAH PERSPEKTIF Majalah Obat Tradisional KOVALEN: Jurnal Riset Kimia Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Biologi Tropis Jurnal Ilmiah Manuntung Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ CARADDE: Jurnal Pengabdian Kepada Masyarakat JPSCR : Journal of Pharmaceutical Science and Clinical Research JIMR - Journal of Islamic Medicine Research PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Jamu Indonesia Jurnal Mandala Pharmacon Indonesia Lentera Acitya Journal Of Health Majalah Farmasetika Indian Journal of Forensic Medicine & Toxicology Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat Proceeding of Mulawarman Pharmaceuticals Conferences Jurnal Farmasi Sains dan Praktis Jurnal Sains dan Teknologi Farmasi Indonesia Jurnal Kesehatan Lentera Acitya Jurnal Pengabdian Farmasi dan Sains Journal of Tropical Pharmacy and Chemistry Jurnal Sains dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Indonesian Journal of Jamu Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran
Joni Tandi, Joni
Program Studi S1 Farmasi, Sekolah Tinggi Ilmu Farmasi Pelita Mas Palu
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Kajian Pengobatan Asma Bronkial pada Pasien Dewasa di Instalasi Rawat Inap RSU Anutapura Palu Joni Tandi
Jurnal Kesehatan Lentera Acitya Vol 4, No 4 (2017): Jurnal Kesehatan Lentera Acitya
Publisher : Nursing Faculty of Fatima Nursing Academy of Parepare

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Telah dilakukan penelitian tentang Kajian Asma Bronkial Pada Pasien Dewasa Di Instalasi Rawat Inap Rumah Sakit Umum Anutapura Palu dengan tujuan untuk mengetahui pengobatan asma bronkial pada pasien dewasa di RSU Anutapura Palu berdasarkan interaksi obat, kontraindikasi dan efek samping. Populasi penelitian adalah semua pasien yang menderita asma bronkial yang menjalani rawat inap di RSU Anutapura Palu, sedangkan sampel penelitian adalah pasien asma bronkial yang dirawat inap di RSU Anutapura Palu selama penelitian dilakukan menggunakan rancangan participant observation dengan pndekatan cross sectional menggunakan teknik accidental sampling. Parameter yang digunakan adalah persentase kesesuaian obat berdasarkan dosis, indikasi, interaksi obat, kontraindikasi dan efek samping obat. Hasil penelitian menunjukkan bahwa persentase penggunaan obat berdasarkan tepat indikasi yang sesuai adalah 100%, persentase interaksi obat 100% tidak terjadi interaksi obat dan persentase penggunaan obat berdasarkan efek samping obat yang sesuai adalah 100%.
Enzymatic virgin coconut oil effect on urea and creatinine levels of hypercholesterolemia-diabetics induced Wistar male rats Niluh Puspita Dewi; Syafika Alaydrus; Nadila Nadila; Magfirah Magfirah; Joni Tandi; Viani Anggi; Nani Astria
Pharmaciana Vol 14, No 1 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i1.27489

Abstract

Coconut (Cocos nucifera) is an Indonesian commodity that has high economic value tall. Virgin Coconut Oil (VCO) is one of the processed coconut products whose selling value is very high, because The composition of VCO consists of medium-chain fatty acids that can maintain a healthy body and prevent various diseases. The process of making VCO used in This research is an enzymatic method using pineapple weevil as a bromelain enzyme. This study aims to determine the effect of enzymatic administration of VCO and an enzymatic dose of VCO which is effective in reducing urea and creatinine levels in hypercholesterolemic-diabetic male white rats (Rattus norvegicus). This study was an experimental laboratory with a modified pretest and posttest randomized controlled group design using 30 test animals which were divided into 6 treatment groups. Each group consisted of 5 test animals, namely normal control, negative control, and positive control, with doses of 0.2, 0.4, and 0.8 mL/kg BW. The data obtained were analyzed using a One Way Anova and non- parametric statistical test by Kruskal Wallis. test and followed by a further Mann Whitney test to determine differences between treatments. The results showed that enzymatic VCO at a dose of 0.8 mL/kg BW was an effective dose in reducing urea and creatinine levels with an average decrease of 17.40 mg/dL and 0.36 mg/dL. The novelty in this study showed that the enzymatic VCO had an effect on reducing urea and creatinine levels in diabetic hypercholesterolemic male white rats.
PEMANFAATAN TUMBUHAN SEBAGAI OBAT DIABETES MELLITUS DI DESA LAMPO, KEC. BANAWA, KAB. DONGGALA Joni Tandi; Ficanata Adhiguna Toding; Ni Putu Intan Riani; Alfia Dewi
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 2 No. 1 (2023): Oktober 2023
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2023.v2.i1.16421

Abstract

Obat tradisional adalah bahan atau ramuan berbahan tumbuhan, hewan, mineral, sediaan sarian (galenik), atau campuran dari bahan tersebut yang secara turun temurun telah digunakan untuk pengobatan. Penggunaan obat tradisional ini di era moderinisasi ini diperkuat oleh riset-riset yang ada dengan data yang kompelementer membuat masyarakat lebih memilih pengobatan dengan menggunakan bahan-bahan alami. Diabetes merupakan penyakit yang tidak asing dalam kehidupan kita sehari-hari yang dapat diobati menggunakan obat-obatan dari tumbuhan. Diabetes merupakan masalah kesehatan yang banyak menarik perhatian karena angka prevalensi yang bertambah setiap tahunnya, terutama di negara berkembang seperti di Indonesia. , sehingga perlu adanya edukasi pemanfaatan tumbuhan obat diabetes mellitus di masyarakat desa Lampo. Edukasi melalui penyuluhan dengan metode ceramah interaktif. Efektivitas penyuluhan ini dapat diuji dengan pemberian kuisiner kepuasan mitra terhadap kegiatan yang dilaksanakan. Hasil pengamatan kegiatan menunjukkan 95% mitra merasa puas dengan edukasi tersebut.
Subchronic Toxicity Test of Purple Leaves Ethanol Extract (PLEE) on the Histopathological Picture of the Lymph of Wistar Rats and Antioxidant Activity Darmayanti; Niluh Puspita Dewi; Mariyani; Joni Tandi; Meike Rachmawati; Yuliet Susanto
Jurnal Penelitian Pendidikan IPA Vol 10 No 7 (2024): July
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i7.8070

Abstract

This study aims to determine the toxic effects of purple leaf ethanol extract on lymph organs at doses of 500; 2.000; and 5.000 mg/kgBB administered for 28 days and and to determine the antioxidant activity of purple leaf Graptophyllum pictum (L.) This study is an experimental study with a random group design, using 20 test animals divided into 4 groups consisting of two treatment groups, namely in the normal control group given Na-CMC 0.5% and the experimental group given PLEE (k1: dose 500 mg/kgBB, k2: dose 2.000 mg/kgBB and k3: dose 5.000 mg/kgBB hematoxylin-eosin staining (HE) using a computer-connected Motic BA210 microscope with 40X magnification in 5 fields of view and antioxidant test using DPPH method with UV-Vis Spectrophotometer at 516 nm wavelength with concentration 20, 40, 60, 80, and 100 ppm. The results showed that leaf ethanol extract was toxic at a dose of 2.000 mg/kgBB – 5.000 mg/kgBB against the diameter of lymphatic organ pulp, organ index and organ weight, there were symptoms of toxicity and purple leaf ethanol extract had strong antioxidant activity with 66.26 μg/mL.
UJI TOKSISITAS SUB KRONIS EKSTRAK DAUN UNGU TERHADAP GAMBARAN HISTOPATOLOGI GINJAL TIKUS PUTIH JANTAN I Made Dipayana; Niluh Puspita Dewi; Magfira; Joni Tandi; Wayan Wirawan; Meike Rachmawati; Nur Azizah
Jurnal Penelitian Pendidikan IPA Vol 10 No 8 (2024): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i8.8312

Abstract

Traditional herbal medicine has become increasingly popular as an alternative to conventional medical treatments. Although the plant offers numerous health benefits, caution should be exercised regarding its long-term use. Long-term use of traditional herbal remedies can have detrimental effects on the kidneys. This study was designed to assess the histological changes in the kidneys of male rats following 28 days of purple sage leaf extract administration and to identify potential harmful effects. The study utilized 20 male Wistar rats and utilized a randomized group design for the experimental methodology. Rats were categorized into four distinct groups, consisting of one control group and three treatment groups. The control group received solely sodium chloride, whereas the treatment group 1 (P1) received 500 mg/kg BB of purple sage ethanol extract. Treatment group 2 received up to 2000 mg/kg BB of purple sage ethanol extract, while treatment group 3 received up to 5000 mg/kg BB. The oral examination was conducted for a duration of 28 days. The treatment groups showed an increase in weight and organ index of the right kidney. The findings suggest a potential for toxicity resulting from the administration of purple sage leaf extract over a duration of 28 days.
The Effect of Binahong Leaves (Anredera cordifolia Steenis) Extract on Blood Urea Nitrogen (BUN) Creatinine Serum and Renal Histopathology of Male White Rats (Rattus norvegicus) with Diabetes Mellitus Tandi, Joni; Patala, Recky; Towulu, Dessy Gracelia; Lidongi, Putri Marcelita; Handayani, Tien Wahyu; Kanan, Maria
Majalah Obat Tradisional Vol 28, No 3 (2023)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.85034

Abstract

Diabetic nephropathy is one of the complications of diabetes mellitus on the pancreas that can end up in chronic pancreas failure. Various treatment options to repair pancreas damage due to diabetic nephropathy, one of which is by using Anredera cordifolia leaves. This study aims to determine the content of secondary metabolites in Anredera cordifolia leaves ethanol extract, and to determine the effective dose of Anredera cordifolia leaves ethanol extract in regenerating male white rat kidney cells. This study uses a laboratory experimental method. This study used 30 rats divided into 6 treatment groups, each group consisting of 5 test animals, namely normal group, negative control, positive control, dose of 25 mg/kg BW, dose 50 mg/kg BW, and dose 100 mg/kg bw. The level of histological damage to the renal tubules was observed with HE staining using an Olympus CX23 microscope. The data from the scoring of the level of renal tubular damage were analyzed using the Kruskal-Wallis test followed by the Mann-Whitney test to see the differences between treatments. The results showed that the Anredera cordifolia leaves ethanol extract contained secondary metabolites of alkaloids, flavonoids, saponins, and tannins; Anredera cordifolia leaves ethanol extract has an effect on kidney cell repair; Anredera cordifolia leaves ethanol extract at a dose of 100 mg/kg bw is effective reducing urea and creatinine; with an average decrease of 17.0 and 0.71 mg/dL in repairing kidney cells with an average damage value of 1.
Pembuatan Minyak Gosok Herbal Di Desa Sopu Kecamatan Nokilalaki Kabupaten Sigi Tandi, Joni; Astuti, Dewi Qurrotul; Pasang, Sisilia Baan
Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat Vol. 3 No. 5 (2023): September 2023 - Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat
Publisher : Indonesian Scientific Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59395/altifani.v3i5.466

Abstract

Penggunaan bahan alami yang murni oleh masyarakat dan digunakan secara turun temurun berdasarkan kepercayaan dan keyakinan masyarakat setempat yang merupakan warisan leluhur dinamakan Obat tradisional. Penggunaan bahan alami ini diyakini tidak memberikan efek samping dan aman digunakan hingga sampai saat ini salah satu sediaan bahan alami ini yang merupakan racikan masyarakat yang pada umumnya dilakukan di Sulawesi Tengah adalah minyak gosok. Minyak gosok adalah minyak herbal yang dapat digunakan untuk mengobati gatal, pegal-pegal sampai rematik yang dapat memberikan rasa hangat, sehingga dapat memberikan rasa yang nyaman dan segar. Dalam kegiatan pengabdian masyarakat ini dilakukan demostrasi pembuatan minyak gosok secara langsung dengan harapan masyarakat dapat menambah pengetahuan tentang cara pembuatan minyak gosok dari bahan-bahan alami dan dapat dijadikan usaha mandiri oleh masyarakat Desa Sopu.
TESTING THE EFFECTS OF PAPAYA LEAF EXTRACT ON THE HISTOPATHOLOGICAL FEATURES OF THE STREPTOZOTOCIN-INDUCED PANCREATIC OF MALE WHITE RATS tandi, joni
Indonesian Journal of Pharmaceutical Science and Technology 2024: Suppl. 6, No. 1 (Special Issue for Mulawarman Pharmaceutical Conference)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v6i1.53705

Abstract

Sasar penelitian ini ialah untuk mengetahui dosis terbaik untuk histologi pankreas dan metabolits sekunders pada konsentrat etanolik daun pepaya (Carica papaya L). Penelitian ini merupakan percobaan laboratorium dengan 30 ekor tikus sebagai hewan uji. Hewan uji di bagi menjadi enam kelompok perlakuan masing-masing lima ekor tikus. Suspensi Na-CMC diberikan pada kelompok 2 (control negatif), glibenklamid diberikan pada kelompok 3 (control positif), dan 100, 200, dan 300mg/kgBB konsentrat etanol daun pepaya (Carica papaya L) diberikan pada kelompok 4, 5, dan 6. Konsentrat etanol daun pepaya mengandung senyawa metabolits sekunders antara lain alkaloids, flavonoids, saponins, dan tanins, sesuai temuan. Pepaya Etanol daun pepaya secara bermakna mempengaruhi gambaran histopatologi pankreas, Etanol daun pepaya terpisah pada porsi 300mg/kgBB merupakan bagian yang mempengaruhi gambaran histopatologi pankreas dengan skor tipikal 1,2.
Aktivitas Hepatoprotektif Ekstrak Daun Binahong (Anredera cordifolia (Ten.) Steenis) pada Tikus Diabetes Melitus Tandi, Joni
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 5, No. 2 (2023) Special Issue for The 3rd Bandung International Teleconference on Pharmacy (B
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v0i0.50555

Abstract

Tanaman binahong (Anredera cordifolia (Ten.) Steenis) merupakan salah satu tumbuhan herbal yang memiliki khasiat sebagai tanaman bahan obat yang digunakan untuk berbagai penyakit sepeti kerusakan hati, diabetes, jantung, tekanan darah tinggi, muntah darah. Tujuan dari penelitian ini adalah mengetahui kadar metabolit sekunder dengan spektrofotometri UV-Vis dan uji antioksidan  serta aktivitas hepatoprotektif daun binahong. Metode yang digunakan dalam penelitian ini adalah spektrofotometri UV-Vis dan DPPH serta uji lanjut Kruskal-Wallis dan uji ManWhitney terhadap hepar tikus diabetes melitus. Hasil analisis kualitatif Ekstrak Daun binahong mengandung senyawa metabolit sekunder seperti Alkaloid, Flavonoid, Saponin dan Tanin. Pada Uji kuantitatif diperoleh kadar total untuk flavonoid adalah 0,2433% b/b, saponin 0,1631% b/b, tanin 0,2512% b/b dan alkaloid 0,0350% b/b dan aktivitas antioksidan ekstrak etanol daun binahong diperoleh hasil berdasarkan nilai IC50 sebesar 61,9 ppm termasuk dalam kategori antioksidan kuat. Pada histopatologi hewan uji diinduksi dengan streptozotocin dan diberikan perlakuan masing-masing kelompok kontrol normal yang tidak diinduksi, kontrol negatif Na CMC 0,5%, kontrol positif  Metformin, kelompok uji yang diberikan ekstrak masing-masing dengan dosis 25, 50 dan 100 mg/kg BB. Pada penelitian ini ekstrak daun binahong  memiliki aktivitas sebagai hepatoprotektor pada dosis 100 mg/BB tikus diabetes melitus.
The Effectiveness of Ethanol Extract of Robusta Coffee Seeds on Blood Glucose, Urea, and Creatinine Levels of Male White Rats Induced by Streptozotocin: Efektivitas Ekstrak Etanol Biji Kopi Robusta terhadap Kadar Glukosa Darah, Urea, dan Kreatinin Tikus Putih Jantan yang Diinduksi Streptozotocin Tandi, Joni; Marsella, Mimi; Suarsana, I Made Agus; Dewi, Niluh Puspita; Magfirah, Magfirah; Handayani, Tien Wahyu; Kanan, Maria
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 9 No. 2 (2023): (October 2023)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2023.v9.i2.16352

Abstract

Background: Traditional medicine plays a role in alternative treatment systems for diabetes mellitus. Objectives: This study aimed to screen the secondary metabolite of the ethanol extract from robusta coffee (Coffea canephora Pierre) seeds. We aimed to clarify the effects of these extracts on blood glucose, urea, and creatinine levels in Streptozotocin-Induced Diabetic Rats. Material and Methods: Phytochemical screening of extracts was carried out qualitatively according to standard methods. The rats were administered ethanol extracts of C. canephora Pierre seeds at doses of 100, 200, and 300 mg/kg body weight for 28 days. Blood glucose, urea, and creatinine levels were then compared between the control and diabetes groups. Results: The ethanol extract of C. canephora Pierre seeds contains alkaloids, flavonoids, saponins, and tannins. Group doses of 100-300 mg/kg body weight can significantly reduce blood glucose, urea, and creatinine levels. It can be concluded that the ethanol extract C. canephora Pierre seeds is a potential source of antidiabetic. Conclusions: The ethanol extract of C. canephora Pierre seeds shows potential as an antidiabetic agent.
Co-Authors Afriani S Afrizal Agustinus Widodo Alaydrus, Syafika Alfia Dewi Anita Purwantari Asrifa Asrifa Astuti, Dewi Qurrotul Ayu Martina Ayu Wulandari AYU WULANDARI Ayu Wulandari Azwaajum Mutahharah Basilingan, Aprince Bella Melinda Cinda Pradita Sudar Claresta, Jong A. Darmayanti David Pakaya David Pakaya Debora Rislianti Lakiu Dewi Astuti Dhitania Ivana Harliwong Dian S. Waruwu Diana Pratiwi, Franciska Erdy Prasetyo Fahruddin Fahruddin Faisal Rahmat Nugraha Fajar Alan Feiverin Tibe Ficanata Adhiguna Toding Gabriella Bamba Ratih Lintin Gusti Ayu Gusti Ayu, Gusti Handayani KR Handayani, Tien Wahyu Handayani, Tien Wahyuni Hastuti L I Made Dipayana Ida Yanti Palinggi Irwan Irwan Islamiati, Utami Jong A. Claresta Kiki Rizki Handayani Kurnia Gatot Novrianto L, Wahyudin H Lakiu, Debora Rislianti Lexy Kareba Lidongi, Putri Marcelita Lina Hardianti Rukmana M, Yulan Magfira Magfira Magfirah Magfirah, Magfirah Magfiroh Magfiroh Maria Kanan Mariyani Marsella, Mimi Marzela Dewi Meike Rachmawati Moh Rizky Moh. Roem Muhammad Agus Muljanto Muthi’ah H Z Na'i, Alpina Nadila Nadila Nadira Nani Astria Ni Made Irma Mariani Ni Putu Intan Riani Ni Putu Setiawati Ni Wayan Ika Purwasih Niluh Puspita Dewi Niluh Puspita Dewi Niluh Puspita Dewi Niluh Puspita Dewi, Niluh Puspita Niswatulfahriyati Niswatulfahriyati Novalia Merue Nur Azizah Nur Ikhwan Nurhikmah Nurhikmah Nurmadinah Nurmadinah Nurul Ulzmi Ovan Nugroho Pegia Parobe, Alda Iglesias Pasang, Sisilia Baan Puspita Dewi, Niluh Putu Intan R, Yana Novika Rahmawati D Rasmiyanti, Ni Kadek Evy Recky Patala Rezky Yanuarty Rio Mariani Risna Yanti Rivani Tampang Rizaldy Lalu Ronaldy Nobertson Ruterlin, Valen Salsabila, Unik Hanifah Sasdila, Sasdila Seblin Tonapa Rammang Solehah, Puput Octaviani Sri Mulyani Sri Mulyani Sri Mulyani Sri Mulyani Sabang Sririzqi Muthmainnah Stely Gracia Bengkati Suarsana, I Made Agus Surat, Megawati R. surisna, surisna Syafika Alaydrus Tamunu, Jeine Sweet Natasya Tarusu, Fikhta Agnesya Tiara Anastasya Tien Wahyu Handayani Tien Wahyu Handayani Tien Wahyu Handayani Tien Wahyu Handayani Tien Wahyu Handayani Tien Wahyu Handayani Tien, Tien Wahyu Handayani Tonapa Rammang, Seblin Towulu, Dessy Gracelia Tuldjanah, Muthmainah Utami Islamiati Utami, Indah Kurnia Valen Ruterlin Veronika Veronika Viani Anggi Vidya Christin Wahyu Handayani, Tien Wahyu Nur Afandi WAYAN WAYAN Wayan Wirawan Wirawan W Wirawan, Resky Chandra Yana Novika R Yanti Palinggi, Ida Yanuarty, Rezky Yasinta Rakanita Yuli Fitriana Yuliet Yuliet Yulistien Yusuf Yunlis Silintowe Kenta Yusriadi Yusriadi Yustin Yustin Zulfaidah