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All Journal International Journal of Public Health Science (IJPHS) Promotif: Jurnal Kesehatan Masyarakat Jurnal Kedokteran Anatomica (Anatomica Medical Journal) Majalah Farmaseutik Journal of Epidemiology and Public Health Indonesian Journal of Medicine Journal of Health Promotion and Behavior Oceana Biomedicina Journal INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Global Health research AgriHealth: Journal of Agri-food, Nutrition and Public Health Maternal and Neonatal Health Journal: INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL Jurnal Impresi Indonesia Pediatric Sciences Journal Journal of Current Health Sciences Asian Journal of Health Research CoMPHI Journal : Community Medicine and Public Health of Indonesia Journal Hang Tuah Medical Journal Prominentia Medical Journal Jurnal Adijaya Multidisiplin Journal of Pharmaceutical and Sciences. JPMP Surabaya Biomedical Journal Jurnal Kedokteran Meditek Jurnal Lentera Kesehatan Masyarakat (JLKM) Svāsthya: Trends in General Medicine and Public Health Journal of Medicine and Health Technology Surabaya Biomedical Journal
Ronald Pratama Adiwinoto
Universitas Hang Tuah
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Journal : Svāsthya: Trends in General Medicine and Public Health

 1 
From silos to systems: Reimagining zoonotic neglected tropical disease management through the lens of one health Ronald Pratama Adiwinoto; I Made Dwi Mertha Adnyana; Soedarsono Soedarsono; Tasalina Yohana Parameswari Gustam
Svāsthya: Trends in General Medicine and Public Health Vol. 1 No. 3 (2024): November 2024
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v1i3.61

Abstract

Zoonotic neglected tropical diseases (zNTDs) pose significant global public health challenges, particularly in low-income and middle-income countries. Traditional siloed approaches to zNTD management have proven inadequate for addressing the complex interplay between human, animal, and environmental health factors. This review examined the limitations of fragmented strategies and explored the potential of integrated one-health approaches for more effective zNTD control. This narrative review covered publications from 2000 to 2023, sourced from databases including PubMed and Scopus, emphasizing studies that met inclusion criteria of peer-reviewed research focused on zNTDs through a One Health lens. A comprehensive analysis of the current literature and case studies was conducted to evaluate the multifaceted drivers of zoonotic pathogen spillover, assess the economic and health impacts of zNTDs, and identify successful implementation of the One Health strategy in endemic regions. This review highlights the inadequacies of siloed disease management approaches, which often lead to inefficient resource allocation and missed opportunities for synergistic intervention. Successful case studies have demonstrated the effectiveness of the One Health strategy in improving disease surveillance, enhancing cross-sectoral collaboration, and achieving sustainable health outcomes. The potential of emerging technologies and innovations to support integrated approaches has also been explored. Transitioning from siloed to systemic approaches in zNTD management requires overcoming institutional barriers, fostering cross-sector collaboration, and implementing multitiered frameworks that operate at the local, national, and global levels. Investing in cross-sectoral capacity development and leveraging technological innovations are crucial for building a workforce capable of addressing the complex challenges posed by zNTDs. Adopting the One Health principle offers a promising path toward more comprehensive, efficient, and sustainable strategies for zNTD prevention.
Raising the flag of vigilance on Mpox outbreak in Indonesia: are we prepared? I Made Dwi Mertha Adnyana; Sidik Maulana; Lutfian Lutfian; Ronald Pratama Adiwinoto
Svāsthya: Trends in General Medicine and Public Health Vol. 1 No. 2 (2024): September 2024
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v1i2.63

Abstract

In the wake of the COVID-19 pandemic, the world has become acutely aware of the devastating impact of infectious diseases on public health, economies, and societies. As we gradually recover from the aftermath of COVID-19, another potential threat looms on the horizon, mpox, formerly known as monkeypox. The recent surge in mpox cases worldwide has prompted health authorities to sound an alarm, and Indonesia, as a populous nation with a complex healthcare system, must ask itself: Are we prepared for this emerging challenge?. The question "Are we prepared?" may not have a simple yes or no answer. Instead, it should serve as a reminder of the need for vigilance, adaptation, and continuous improvement in public health systems. As we navigate this new health challenge, the true measure of Indonesia's preparedness is its ability to respond swiftly, effectively, and equitably to protect the health and well-being of all citizens.
Neutrophil–lymphocyte ratio as a predictor of dengue hemorrhagic fever severity in Indonesian pediatric patients: A Single-center retrospective study Dewi, I Gusti Ayu Ajeng Widia Kencana; Adiwinoto, Ronald Pratama; Rokhmadhoni Pikir, Rizqi; Rusli, Christina; Biutifasari, Verna; Diah Utami, Prawesty
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 4 (2025): July 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v2i4.104

Abstract

Dengue hemorrhagic fever (DHF) is a significant health burden in Indonesia, necessitating reliable prognostic markers for early clinical intervention. The neutrophil‒lymphocyte ratio (NLR) has emerged as a potential biomarker for disease severity assessment, although its utility in pediatric populations requires further validation. This study aimed to to determine the relationship between the neutrophil‒lymphocyte ratio and DHF severity grade in pediatric patients and evaluate its potential as a prognostic indicator for clinical decision-making. This retrospective cross-sectional study analyzed 111 pediatric patients aged 5-14 years who were diagnosed with DHF at RSPAL Dr. Ramelan, Surabaya, between January 2022 and December 2024. Patients were classified according to the WHO severity grades (I-IV), with the NLR calculated from complete blood counts obtained during days 3-6 of illness. Statistical analysis with Spearman's rank correlation was used to examine the relationship between the NLR and disease severity. The study population predominantly demonstrated Grade I DHF (56.8%), followed by Grade II DHF (20.7%), Grade III DHF (18.0%), and Grade IV DHF (4.5%). Patients with lower severity grades (I-II) predominantly presented low NLR values (<1) in 46.0% and 47.8% of cases, respectively, whereas those with higher severity grades (III-IV) primarily presented normal NLR values (1-3) in 65.0% and 60.0% of cases, respectively. Spearman's correlation analysis revealed no statistically significant relationship between the NLR and DHF severity (ρ = 0.120, p = 0.208). The neutrophil‒lymphocyte ratio has limited utility as a standalone predictor of DHF severity in pediatric patients. These findings suggest the need for alternative biomarkers or composite indices for accurate prediction of pediatric DHF severity.
Co-Authors Abdul Azis, Bima ADAM, OLIVIA MAHARDANI Adisyahputra, Vega Adnyana , I Made Dwi Mertha Agung Dwi Wahyu Widodo Agung Pranoto Al Hasan, Hafidz Ramadhan Alpha Fardah Athiyyah Angelica Kresnamurti Ariewibawa, Fariz Atiqi Artha Budi Susila Duarsa Astrid Kusuma Avelline, Kendraadine Dheayu Baita, Etina Noor Biutifasari , Verna Biutifasari, Verna Brilliandinda Ichsasqia Sidqi Auliayahya Brilliant , Fahridho Ramadhana Cahya Yudha Laksmana Putra Devanda, Kasilda Pasha Dewi, I Gusti Ayu Ajeng Widia Kencana Dewindra Candra Puspita, Amalia Diah Utami, Prawesty Diana, Adawiyah Putri Dinda Umardy, Fairuziah Distyvanya, Shakira Azzahra Dwinka Syafira Eljatin Dwitama Adiwinoto, Robert E.J.T, SIHNING Effendi, Muchiddin Andri Setyo Eka Fitriani Hafel Erina Yatmasari Ersanda Nurma Fathir Fadhilah, Yahdiyan Febri Endra Budi Setyawan Florentina Sustini Graciela, Anne Maria Hadi, Janto Poernomo Hamdy, Irza Hasanal Hardiono Hardiono, Hardiono Hardjono, Ellen Angelique Haris, Ivana Angelica Hayati, Khofifah Bela Rachmanu Helda Dwiana Sari HENDRATA ERRY ANDISARI2 Herdiyantini, Mita Heru Nurdianto Hibatullah, Faiz Nur Hidajat, Boerhan Ida Ayu Govinda Lazenobia De Sanjaya Putri Izzah Al Nabilah Jongky Hendro Prajitno Kalada, Elisabeth Chelsea Uma Ketut Edy Sudiarta Kharizmatika Kurnia Cahya, Sekar Lauwis, Keziah Queency Lavenda Diarnasa Zihara Safira Levina Larassanti Liliawanti Liliawanti Liliawanti Liza Yudistira Yusan Lutfian Lutfian M. Shadiqul Amin Made Ayu Mira Cyntia Dewi Made Maylisca Theresia Mulya Diprasta Made Peni Juliana Maliku Nurrochman Widandi Manata Wijaya Sasmita Martono, Alicia Stevina Maulana Muchammad Aunun Najib Medina, Nadra Odifa Meiriyanti Dhita Mentari Nata Kusuma Michael Bramantya Michelle Madeline Maydavania Mita Herdiyantini MOCHAMAD ALVIRIO NEDYA RIZKA Muhammad Kalaznykov MUHAMMAD RIZAL Nadya Aisyah Sasqia Putri Nahdah, Jaudah NANDA ABIGAIL Nelya Rindayu, Dinnara Ni Luh Gede Sudaryati Norholila Nugraheni, Pramita Anindya Oki Nugraha Putra Oki Nugraha Putra Peppy Nawangsasi Peter Gunawan Tandean Pikir, Rizqi Rokhmadhoni Poerwanto, Eka Pramita Anindya Nugraheni Pramudita Riwanti Prasasti, Vincentia Prasetya, Hanung Prasetyadi , Frans O.H. Prima Arundani Purmata, Andrew Theo William Chris Putra, Fabianus Yvan Marino Cahaya Putra, Oki Nugraha Putri, Fernita Naomi Putri, Jeanaya Hedya Alfara Putri, Jenniefer Clarissa Raharja, Febrila Tarisa Rahmadita, Annisa Putri Rasyida, Annisa Ullya Renata Prameswari Retno Budiarti Retno Budiarti Riami Ristanti, Safira Roanna Gabrielle, Vania Robert Dwitama Adiwinoto Rokhmadhoni Pikir, Rizqi Rr. MUTIARA DEVANIA SAMARA QALBA Rusli, Christina S. Soedarsono Sadya Wendra SAES, JOVITASARI ELVIANA PUTRI Safira, Vita Sandy, Emy Noviana Santoso, Clara Cindy Ateng Saptono Putro Setyawan, Yuswanto Sianipar, Habel Ryan Annerico Sidik Maulana Soelistijo, Soebagijo Adi Sri Umijati STEFANUS DJONI HUSODO Sudiarta, Ketut Edy Sulistiawati Sulistiawati Sulistiawati Sulistiawati Sulistio, Timothy Sunur, Vincentius William Syed Meesam Raza Sylvia Rizki Tamam Jauhar Tasalina Yohana Parameswari Gustam Tasalina Yohana Parameswari Gustam Titong Sugihartono Ubaid, Angling Febriani Ariqoh Ulwani, Qulistan Balqis Usman Hadi Utami , Prawesty Diah Vivien Earlyanti, Callista Wahyu Prasasti Mutiadesi Wahyu Prasasti Mutiadesi Widati Fatmaningrum Widjajanto , Hendra Wijaya, Jennifer Wijaya, Rike Andy Wijayaningrum, Lena Zeeva, Evane Jovanie Zenjaya, Kellyn Trycia Zito Viegas da Cruz Zunnahri, Salsabila Qurrotul Aini