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All Journal HAYATI Journal of Biosciences Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy) Jurnal Gizi dan Pangan Jurnal Teknologi Dan Industri Pangan Jurnal Pengolahan Hasil Perikanan Indonesia VALENSI Jurnal Veteriner JURNAL KIMIA SAINS DAN APLIKASI BIOTROPIA - The Southeast Asian Journal of Tropical Biology Current Biochemistry Indonesian Journal of Pharmaceutical Science and Technology Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Media Gizi Indonesia (MGI) Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Aplikasi Teknologi Pangan QARDHUL HASAN: MEDIA PENGABDIAN KEPADA MASYARAKAT Jambura Journal of Chemistry Jurnal Entomologi Indonesia Journal of Telenursing (JOTING) JSMARTech : Journal of Smart Bioprospecting and Technology Indonesian Journal of Applied Research (IJAR) Wood Research Journal : Journal of Indonesian Wood Research Society Wood Research Journal : Journal of Indonesian Wood Research Society Jurnal Pusat Inovasi Masyarakat Jurnal Sylva Lestari JURNAL AGROINDUSTRI HALAL Jurnal Sosial dan Sains Jurnal Ilmiah Multidisiplin Nusantara Jurnal Veteriner dan Biomedis Journal of Fisheries & Marine Halal Studies and Society Buitenzorg: Journal of Tropical Science
DIMAS ANDRIANTO
Departemen Biokimia, Fakultas Matematika Dan Ilmu Pengetahuan Alam, Institut Pertanian Bogor, Bogor 16680
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Journal : VALENSI

 1 
Flavonoid Concentration and Tyrosinase Inhibition Activity of Ethanol Extract of Piper crocatum (Piper crocatum var. Ruiz & Pav) from Various Regions in Indonesia and Their Correlations Irsal, Riyan Alifbi Putera; Safithri, Mega; Andrianto, Dimas; Mardliyati, Etik
Jurnal Kimia Valensi Jurnal Kimia VALENSI Volume 9, No. 1, May 2023
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v9i1.31426

Abstract

Hyperpigmentation is a condition of darkening of the skin which is generally caused by an increase in melanin production. Melanin is produced in melanocytes by the enzyme tyrosinase. Piper crocatum contains flavonoid compounds that are known from previous research to inhibit tyrosinase. The goals of this study were to determine the tyrosinase inhibitory activity and total flavonoid content of seven accessions, as well as look at the Pearson’s correlation and clustering PCA (principal component analysis). The method used was water content analysis, extraction yield measurement, total flavonoids analysis, and in vitro tyrosinase inhibition. Based on the results, P. crocatum from Kendari had the best yield and total flavonoid content of 24.07% and 5.10 mg QE g-1, while P. crocatum from Bogor had the lowest water content with a value of 6.21% and the best in tyrosinase inhibition of 13.77. The correlation between total flavonoid content and percent inhibition showed a very weak correlation. The results of clustering formed four clusters of seven accessions based on total flavonoids and percent inhibition. The cluster was divided into Malang (506mDPL) and Jayapura (287mDPL), Banda Aceh (0.80mDPL) and Bandung (670mDPL), Samarinda (8mDPL) and Bogor (190-350m DPL), and Kendari (14mDPL). In conclusion, the correlation between total flavonoid levels and percent inhibition is very weak and regional diversity had a significant effect on total flavonoids and total inhibition.
Amino Acids Isolation from α-keratin of Javanese Goat (Capra hircus) Hair and Garut Sheep (Ovis aries) Hair Waste Using Acid Hydrolysis Method as BCAA Supplement Firdaus, Dzikri Anfasa; Andrianto, Dimas; Darmawan, Noviyan
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 10, No. 1, May 2024
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v10i1.38146

Abstract

Javanese goat and Garut sheep hair contain α-keratin, a protein that can be broken by hydrolysis to produce simpler amino acids. Feather waste generates millions of tons of α-keratin biomass originating from animal slaughterhouses, thereby raising health concerns. The utilization of acid hydrolysis is considered to be more cost-effective compared to enzymatic hydrolysis, and it provides a broader range of amino acid cleavage sites compared to enzymes, which exhibit specific cleavage. This study aimed to isolate amino acids from Javanese goat and Garut sheep hair through acid hydrolysis. The methods included hair sample preparation, acid hydrolysis used 6 M HCL at 110°C, reflux isolation, amino acid separation based on isoelectric pH 4.9 –5.4, functional groups analysis using FTIR, and analysis of amino acid content by HPLC methods. The results showed that the yield produced after isolation on Javanese goat hair samples was 0.92% and Garut sheep hair 0.32%, respectively. The FTIR spectrum showed amino acid functional groups in both samples, including carboxyl (COOH), amine (C-N primer), (C-S disulfide), and amide I (-CONH2). Successful breakdown of α-keratin proteins into simpler amino acids was achieved for Javanese goat and Garut sheep hair. Amino acid analysis of Javanese goat hair isolates revealed the presence of aspartic acid, threonine, serine, glutamate, proline, glycine, alanine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine, histidine, lysine, and arginine amino acids, respectively. The highest content was isoleucine at 0.60% w/w. In conclusion, the isolated amino acids from Javanese goat hair can be used as a halal supplement that serves as nutrition in the body.
Amino Acids Isolation from α-keratin of Javanese Goat (Capra hircus) Hair and Garut Sheep (Ovis aries) Hair Waste Using Acid Hydrolysis Method as BCAA Supplement Firdaus, Dzikri Anfasa; Andrianto, Dimas; Darmawan, Noviyan
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 10, No. 1, May 2024
Publisher : Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v10i1.38146

Abstract

Javanese goat and Garut sheep hair contain α-keratin, a protein that can be broken by hydrolysis to produce simpler amino acids. Feather waste generates millions of tons of α-keratin biomass originating from animal slaughterhouses, thereby raising health concerns. The utilization of acid hydrolysis is considered to be more cost-effective compared to enzymatic hydrolysis, and it provides a broader range of amino acid cleavage sites compared to enzymes, which exhibit specific cleavage. This study aimed to isolate amino acids from Javanese goat and Garut sheep hair through acid hydrolysis. The methods included hair sample preparation, acid hydrolysis used 6 M HCL at 110°C, reflux isolation, amino acid separation based on isoelectric pH 4.9 –5.4, functional groups analysis using FTIR, and analysis of amino acid content by HPLC methods. The results showed that the yield produced after isolation on Javanese goat hair samples was 0.92% and Garut sheep hair 0.32%, respectively. The FTIR spectrum showed amino acid functional groups in both samples, including carboxyl (COOH), amine (C-N primer), (C-S disulfide), and amide I (-CONH2). Successful breakdown of α-keratin proteins into simpler amino acids was achieved for Javanese goat and Garut sheep hair. Amino acid analysis of Javanese goat hair isolates revealed the presence of aspartic acid, threonine, serine, glutamate, proline, glycine, alanine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine, histidine, lysine, and arginine amino acids, respectively. The highest content was isoleucine at 0.60% w/w. In conclusion, the isolated amino acids from Javanese goat hair can be used as a halal supplement that serves as nutrition in the body.
Co-Authors Abdjad Asih Nawangsih Abdul Aziz Abdurrahman Zaky Achyar, Catellia Auliany Agus Setiyono Ahmad Faqih Aisyah Sahara Akhmad Endang Zainal Hasan Al Malik, Ahmad Fauzan Aldri Frinaldi Alexandra, Angelya Cintania Amrista Fanzani Kananga Anja Meryandini Antonius Padua Ratu Apipah Aprianti Arya Arendra Assa’addah, Habibah Aulya, Silvy Ayu Tri Nursyarah Azizah, Annisa Nur Wahida Bella Fatima Dora Zaelani Dadan Rohdiana Daeli, Gavriel Allenfar Danty Oktiana Prastiwi Dara Anggun Vachyra Dasman Lanin Dea Khalissa Anidya Destiandani, Khansa Dewi Eriyanti Dewi Kurniasih Dewi Purnamasari Djarot Sasongko Hami Seno Dwicesaria, Maheswari Alfira Eka Wahyu Purnama Elgiani Yassifa Yulia Nur Insari Emidar Khusnu Eny Ida Riyanti Eriyanti, Dewi Etik Mardliyati, Etik Eva Harlina Fahmi Hafid Faisal Rahman Falah, Samsul Febrina, Adella Fina Febrianti Firdaus, Dzikri Anfasa Firdaus, Muhamad Fajar Firmansyah, Muhammad Ade Fitrilia, Tiana Galuh Adhiyaksa Ashari Ghifari, Muhammad Nabil Gholam, Gusnia Meilin Gina Oktaviani Sabrina Hanifati, Qisthina Hardinsyah Hasanah, Ikromatul Hasim - HASIM DANURI Hasim Hasim Hazim, Naufal Wildan Heddy Julistiono Heddy Julistiono Hudayanti, Martini Husnawati, . I MADE ARTIKA Ike Agustiani Ilham Gilang Cahya Ahmada Iman, Ramadhan Nur Imelia Dewi Inawati Inawati Iqrima Basri Irfan Abdul Aziz Irsal, Riyan Alifbi Putera Istikorini, Yunik Jaka Aryantara Kuntala Kusnaedi, Anggi LAKSMI AMBARSARI Latifah Kosim Darusman Latifah, Aminahtun Lestari, Ella Deffi Lukman, Zulfiqar Madyastuti, Rini Marfiana, Arila Safa Maria Bintang Mega Safithri Mhd. Ridha Muhamad Alvin Adriyan Muhammad Farhan Muhammad Irfansyah Pradika Muhammad Zulkifli Mutholaah Mutmainnah Agustiawan Umar Nabilatusyifa, Alivianisa Nabilla, Rahmah Najmah, Najmah Nayanda, Najwa Putri Nina Tri Kusumawati Noor Farikhah Haneda Noviyan Darmawan Nurliani Bermawie Nusyarah, Ayu Tri Olive Wisepti Pratama Prasetyo, Dwiandra Hadi Purwanto, Ukhradiya Magharaniq Safira Putri, Oyi Candra Santoso Putri, Salsabila Yasmin Budi Qolbiyah, Syifa Ainul Qomariah Hasanah Qurrotu Ayni R. Haryo Bimo Setiarto, R. Haryo Bimo Raden Roro Fine Ayu Putri Rafiqi, Akbar Rahmah, Sabrina Firdayani Raisyadikara, Fadila Rara Annisaur Rosyidah Rembrandt Rimbawan Rimbawan Rini Kurniasih, Rini Riska Susila Putri Rosyidah, Rara Annisaur Sanro Tachibana Sari, Sintia Permata Sigiro, Ria Heni Silvy Aulya Sitanggang, Rianta Faustina Siti Maesunah Gilang Maya Slamet Hamzah Sobari, M Hilmy Rifq Sri Anna Marliyati Sri Mariati Sri Wahyuni Suci Hermita Sulistiyani SULISTIYANI SULISTIYANI Sulistiyani Sulistiyani Syaefudin Syaefudin Syaefudin Syamsul Falah Syarthibi, Ahmad Syifa Khaerani Tukan, Maria Magdalena Nona Motu Ukhradiya Magharaniq Safira Purwanto Ulfah Juniarti Siregar Vina Oktovianti Walidayyin, Sekar Wangi Waras Nurcholis Wilujeng, Retno Winata, Grace Marlina Yudono, Nur Annisa Windi Yupi Yulianita Arifin Yusriya, Rifqi Zaelani, Bella Fatima Dora Zulfikar Muchammad