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Transfer Ilmu Pengetahuan dan Teknologi Produksi Kombucha Bunga Kupu-kupu Antidiabetes bagi Karang Taruna Katajanom di Kelurahan Jayengan Surakarta Tiara Ajeng Listyani; Puguh Ika Listyorini; Anna Fitriawati
Jurnal Pengabdian Ilmu Kesehatan Vol. 6 No. 2 (2026): Juli: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v6i2.7832

Abstract

Type-2 Diabetes Mellitus (T2DM) remains the second highest non communicable disease burden in Surakarta City after hypertension, with regional facilities like Puskesmas Jayengan recording substantial patient visits. Principal risk factors include high sugar and calorie-dense diets, insufficient physical activity, advancing age, and hereditary predisposition. In response, a community service team, chaired by Tiara Ajeng Listyani with members Puguh Ika Listyorini and Anna Fitriawati, implemented an empowerment program for the Katajanom Jayengan Youth Organization (Karang Taruna), supported by the Directorate of Research and Community Service, the Directorate General of Research and Development, the Ministry of Higher Education, Science, and Technology, and Universitas Duta Bangsa Surakarta for the 2026 period. The program transferred knowledge and technology for producing butterfly pea flower (Clitoria ternatea) kombucha as a functional nutraceutical beverage with natural antidiabetic properties. Methods included healthy lifestyle education, self administered blood glucose screening training, SCOBY based fermentation technology transfer, mentorship in production standardization and halal certification, and pre-test/post-test evaluations with daily blood glucose monitoring of partners. Results showed successful development of a nutraceutical product prototype, achieving an initial production target of at least 50 liters of consumption-grade output, along with improved community health evidenced by a 15–20% reduction in blood glucose levels during routine monitoring. The program has broader implications for establishing a self-sustaining, community based production unit supporting community health independence, while opening pathways toward a youth driven creative economy grounded in locally sourced functional food products.
Formulasi dan Uji Antibakteri Sabun Padat Kombinasi Ekstrak Daun Kirinyuh dan Bidara terhadap Staphylococcus aureus ATCC 25923 Andini Natasya; Siwi Hastuti; Anna Fitriawati
Inovasi Kesehatan Global Vol. 3 No. 3 (2026): Agustus: Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v3i3.3388

Abstract

Acne vulgaris is a chronic inflammatory skin condition affecting 80–85% of adolescents, with Staphylococcus aureus infection being one of its main triggers. Kirinyuh leaves (Chromolaena odorata) and bidara leaves (Ziziphus mauritiana) contain antibacterial bioactive compounds such as alkaloids, flavonoids, tannins, and saponins, making the combination of both potentially effective as a natural antiseptic cleanser in solid soap. This study aimed to formulate a solid soap combining kirinyuh and bidara leaf extracts that meets the physical quality standards of SNI 3532:2021, as well as to determine the concentration with optimum inhibitory activity against S. aureus ATCC 25923. This laboratory experimental study used 70% ethanol maceration and saponification of oil bases (VCO, olive, and palm oil) to produce four formulas (F0 as the base control; F1, F2, F3 with varying extract concentrations), which were subsequently evaluated for physical quality, hedonic properties, and irritation in 20 panelists. Antibacterial activity was tested using the Kirby-Bauer disc diffusion method, and the resulting data were analyzed using One Way ANOVA and Tukey HSD tests. All formulas met SNI criteria and caused no irritation, with Formula 2 (2.5% kirinyuh : 7.5% bidara) producing the largest inhibition zone (12.20 ± 0.67 mm, strong category), which was statistically comparable to the positive control, Asepso soap (p = 0.412). This soap effectively inhibited S. aureus with good physical quality, and Formula 2 was determined to be the most optimum concentration.
Relationship Between Drug Related Problems (DRPs) and Length of Stay (LOS) In Congestive Heart Failure (CHF) Patients at Sebelas Maret University Hospital Mel Rinda Nurdilanda; Vivin Marwiyati Rohmana; Anna Fitriawati
Jurnal Pharmacopoeia Vol 5 No 2 (2026): September 2026
Publisher : Poltekkes Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/jp.v5i2.1455

Abstract

Congestive Heart Failure (CHF) is a condition in which the heart is unable to pump blood throughout the body. One critical aspect of CHF management is the use of medications, which is often complex and involves polypharmacy that can potentially lead to Drug Related Problems (DRPs). Length of Stay (LOS) refers to the duration of a patient’s hospital stay. DRPs can worsen CHF symptoms, which may lead to an increase in the LOS. This study aims to analyze the relationship between Drug Related Problems (DRPs) and Length of Stay (LOS) in patients with Congestive Heart Failure (CHF). This analytical observational study used a retrospective design based on medical records of patients with CHF at UNS Hospital from March 2024 to March 2026. DRPs were identified and classified using the Pharmaceutical Care Network Europe (PCNE) V9.1 classification. The relationship between Drug Related Problems (DRPs) and Length of Stay (LOS) was analyzed using the chi-square test. Among 70 patients, 228 DRP events were identified. The most frequently identified DRP category was unknown problem status, with 68 events (29,8%), followed by inappropriate drug combination, with 66 events (28,9%). The most common LOS was <4 days for 40 patients (57,1%), while 30 patients (42,9%) had a stay of ≥4 days. Bivariate analysis showed a statistically significant association between the number of DRPs and LOS (p=0.003). There was a significant association between the number of DRPs and LOS among patients with CHF at UNS Hospital.
Formulasi Dan Evaluasi Sifat Fisik Gel Antibakteri Ekstrak Daun Binahong (Anredera cordifolia) Dengan Variasi Konsentrasi CMC-Na Dan HPMC Rendy Satya Febriansyah; Tatiana Siska Wardani; Anna Fitriawati
Borneo Nursing Journal (BNJ) Vol. 8 No. 2b (2026)
Publisher : Akademi Keperawatan Yarsi Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61878/bnj.v8i2b.2207

Abstract

Infeksi kulit yang bermula dari luka kecil dapat memicu invasi bakteri seperti Staphylococcus aureus sehingga diperlukan pengobatan topikal yang efektif. Daun binahong (Anredera cordifolia) mengandung flavonoid, tanin, alkaloid, dan saponin yang berpotensi sebagai antibakteri. Penelitian ini bertujuan memformulasikan ekstrak etanol daun binahong ke dalam sediaan gel dengan variasi konsentrasi CMC-Na dan HPMC, mengevaluasi sifat fisiknya, serta menguji aktivitas antibakterinya terhadap Staphylococcus aureus. Penelitian menggunakan metode eksperimental laboratorium dengan enam formula gel (F0-F5) yang memiliki variasi rasio CMC-Na dan HPMC. Evaluasi sifat fisik meliputi organoleptik, homogenitas, pH, viskositas, daya sebar, dan daya lekat, sedangkan aktivitas antibakteri diuji dengan metode difusi cakram terhadap formula optimum. Rendemen ekstrak sebesar 12,96% dan seluruh parameter standarisasi simplisia maupun ekstrak memenuhi persyaratan mutu. Skrining fitokimia menunjukkan hasil positif untuk alkaloid, flavonoid, saponin, tanin, dan steroid/terpenoid. Formula F2 (CMC-Na 2%, HPMC 2%) menunjukkan karakteristik fisik paling optimal dengan pH 5,99-6,31, daya sebar 6,15 cm, dan daya lekat 3,70 detik. Uji aktivitas antibakteri menunjukkan F2 menghasilkan zona hambat 7,18 ± 0,72 mm (kategori sedang), lebih tinggi dibanding basis F0 (1,90 ± 0,85 mm), namun masih di bawah kontrol positif klindamisin fosfat 1% (11,92 ± 1,90 mm). Analisis One-Way ANOVA menunjukkan perbedaan signifikan antarkelompok (p<0,05). Ekstrak etanol daun binahong dapat diformulasikan menjadi sediaan gel dengan sifat fisik yang baik dan memiliki aktivitas antibakteri terhadap Staphylococcus aureus.
Co-Authors Abdul Wahab Sabrina, Azimah Adhe Wibawa Mahardika Putra Agustiningrum, Nurul Alya Atla Lidya Aminnulloh, Muhammad Aminnulloh, Muhhamad Aminulloh, Muhammad Andini Natasya Anisa Fadilah Kumala Putri Annie Rahmatillah Bagas Ardiyantoro Bangkit Riska P Bryan Dwi Multi Chofifatun Mubarokah Danang Raharjo Della Puspita Ningrum Diyah Nurayuni Dwi S, Anita Effendi Nursalim Efrilia, Erin Emin Karoba Endang Suciati Fuadhiya, Arina Hendra, Naufal Dhuha Indi yatno, Aurora Shalfa Alkhariza Karim Karim, Karim Kharisma Jayak P Kharisma Jayak Pratama Krisnantari, Ni Luh Novelia Kusumaningrum, Indah Mega Lestari, Vera Fuji Listyani, Tiara Ajeng Mei Vita Rachma Pertiwi Mel Rinda Nurdilanda Muhammad Abdul Azis Muhammad Saad, Muhammad Neha Azziza Cherrysha Alifia Nia Kurniati Niken Luthfiyanti ningsih, endang wahyu Nur Cholis Endriyatno Nurul Agustiningrum Nurul Fatimah Olga Nordeka, Marcela Ones Kotouki P, Kharisma Jayak Peni Indrayudha Permata, Bangkit Riska Pradina Arifah Nurcahyani Pratama, Kharisma Jayak Prity, Intan Puguh Ika Listyorini Qurrota'Ain, Rusyda Raden Rara Anteng Pujowati Rahmad Adji, Alenda Rahmat Hidayat Rahmatillah, Annie Rendy Satya Febriansyah Riska P, Bangkit Riztiandi Ardiansyah Rochayati, Popiy Eko Rohmana, Vivin Marwiyati Sari, Cantyka Eka Viemala Sari, Sindy Avita Septian Maulid W Septian Maulid Wicahyo siska, Tatiana Siwi Hastuti Tanoyo, William Tatiana Siska Wardani Toyang, Gresilia Trianita Septiana Wahyu, Rizka Wardani, Lydia Puspita Wardani, Tatiana Siska Wulandari, Diana