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EDUKASI HERBAL: SOLUSI MINUMAN SEHAT UNTUK MENCEGAH BATUK DAN PILEK PADA ANAK DI DESA NUSAEN, FATULEU TENGAH, KABUPATEN KUPANG Muntasir Muntasir; Muhajirin Dean; Mathias Nathaniel Kolobani; Cahyani Purnasari; RR. Listyawati Nurina; Nurul Fatmawati Pua Upa; Tadeus Andrea Lada Regaletha
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 6 No. 2 (2025): Volume 6 No. 2 Tahun 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v6i2.42692

Abstract

Kesehatan adalah aspek penting dalam kehidupan, terutama di daerah pedesaan yang memiliki akses terbatas terhadap layanan kesehatan. Batuk dan pilek merupakan penyakit umum yang sering menyerang anak-anak, khususnya balita. Penelitian ini bertujuan untuk meningkatkan pengetahuan masyarakat Desa Nunsaen mengenai penggunaan tanaman obat sebagai pencegahan batuk dan pilek melalui edukasi praktis. Metode yang digunakan meliputi ceramah, demonstrasi pembuatan minuman herbal, uji organoleptik produk, dan diskusi interaktif dengan 30 peserta dari berbagai latar belakang. Hasil evaluasi menunjukkan peningkatan pengetahuan yang signifikan; sebelum pelatihan, hanya 25% peserta yang mengetahui manfaat tanaman herbal, sedangkan setelah pelatihan, angka tersebut meningkat menjadi 100%. Selain itu, semua peserta menyatakan akan merekomendasikan penggunaan minuman herbal untuk pencegahan batuk dan pilek pada anak. Kesimpulan dari kegiatan ini adalah bahwa edukasi mengenai tanaman obat efektif dalam meningkatkan kesadaran masyarakat tentang alternatif pengobatan alami dan mendorong pemanfaatan sumber daya lokal untuk kesehatan yang lebih baik.
Perbandingan Pelarut Ekstrak Air, Etanol 70%, dan N-Heksana Herba Utasupe terhadap Kandungan Metabolit Sekunder Menggunakan Skrining Fitokimia Alsen Diamel Oematan; Listyawati Nurina; Desi Indriarini; Anita L. Shinta Amat; Muhajirin Dean
JUKEJ : Jurnal Kesehatan Jompa Vol 5 No 2 (2026): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol5.Iss2.2679

Abstract

Traditional medicine is a medicine that is used for generations from ancestors and inherited until now. The use of herbal medicinal products in the last three decades has increased rapidly. Indonesia is one of the countries that has a lot of biodiversity. Indonesia has millions of varieties of plants that can be used as herbal medicine. Utasupe is a plant that is one of the herbal medicines used by people from Ende Island, Ende Regency, East Nusa Tenggara Province as an herbal medicine for constipation conditions. Knowing the comparison of secondary metabolite compounds of water extract, 70% ethanol, and n-hexane Herba Utasupe from Ende Island District. Research used in true experimental design research with posttest only control group design research design. This study used phytochemical screening methods, to see changes in color/shape that indicate the presence and absence of secondary metabolite compounds present in water extracts, 70% ethanol, and n- hexane Utasupe herbaceous plants from Ende Island District. The sample in this study was Utasupe Herba plants that met the inclusion criteria and exclusion criteria. Data analysis using nonparametric statistical methods, namely the fisher test. In water and ethanol solvents 70% obtained groups of secondary metabolite compounds alkaloids, flavonoids, tannins, and saponins. While in n-hexane solvents obtained a class of secondary metabolite compounds of alkaloids, flavonoids, steroids, and tannins. In statistical analysis using the fisher test, p values were obtained: 0.200 – 0.100 (p > 0.005). The results of this fisher test show that there is no significant difference between the three solvents. There is no comparison between water solvent, 70% ethanol, and n- hexane based on the results of statistical analysis using the Fisher test.
The Relationship Between Depression Levels and Antisocial Behavior Among Students in the Faculty of Medicine at Nusa Cendana University Saka Pamukti Supriyadi; Conrad Liab H. Folamauk; Rr. Listyawati Nurina
Jurnal Sehat Indonesia (JUSINDO) Vol. 8 No. 2 (2026): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/-.v8i2.550

Abstract

The prevalence of psychological distress among medical students is higher than that of the general population, with depression being one of the most commonly reported conditions. Psychosocial disorders, such as stress and depression, may develop into more severe depressive disorders and antisocial behavior if left untreated. This study aimed to identify the relationship between depression levels and antisocial behavior among students at the Faculty of Medicine, Nusa Cendana University. A cross-sectional design was employed in this study. The sample consisted of 122 students from the Faculty of Medicine, Nusa Cendana University, from the 2017, 2018, and 2019 cohorts. Depression levels were measured using the validated Beck Depression Inventory-II (BDI-II) questionnaire, while antisocial behavior was assessed using the Subtypes of Antisocial Behavior (STAB) questionnaire. Data were analyzed using Somers’ d correlation test. The results showed that 86 respondents (70.49%) had minimal or no depression, 19 respondents (15.57%) had mild depression, 11 respondents (9.02%) had moderate depression, and 6 respondents (4.92%) had severe depression. Regarding antisocial behavior, 109 respondents (89.34%) demonstrated low levels of antisocial behavior, 13 respondents (10.66%) demonstrated moderate levels, and no respondents exhibited high levels of antisocial behavior. The analysis revealed a p-value of 0.001 (α < 0.05), indicating a statistically significant relationship between depression levels and antisocial behavior among students. Therefore, this study concluded that depression levels were significantly associated with antisocial behavior among students at the Faculty of Medicine, Nusa Cendana University (p = 0.001).
PENGARUH EKSTRAK ETANOL DAUN SIRIH MERAH (Piper crocatum) TERHADAP GAMBARAN HISTOPATOLOGI OTOT JANTUNG TIKUS (Rattus norvegicus) DIINDUKSI ALOKSAN Riky Alberth Lerrick; Efrisca Meliyuita Br. Damanik; Anita Lidesna Shinta Amat; Rr. Listyawati Nurina
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.22056

Abstract

Introduction: Red betel leaves (Piper crocatum) contain flavonoids, alkaloids, saponins, and tannins, which have antidiabetic properties. Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia due to impaired insulin secretion or action, leading to increased production of Reactive Oxygen Species (ROS). The antioxidants in red betel leaf extract are expected to reduce ROS formation and protect cardiac muscle from DM-induced damage.. Methods: This laboratory experimental study used a true experimental post-test only control group design. Thirty rats were divided into five groups: positive control (KK+), negative control (KK−), and treatment groups (KP1, KP2, KP3), each consisting of six rats. Histopathological features of cardiac muscle, including interstitial fibrosis, ventricular myocyte hypertrophy, and intramyocyte lipid deposits, were assessed. Data were analyzed using the Kruskal-Wallis test and Post Hoc LSD. Results: There was a significant difference in ventricular myocyte hypertrophy between groups (p = 0.009), but no significant differences were observed in interstitial fibrosis (p = 1.000) and intramyocyte lipid deposits (p = 0.866). Discussion: Red betel leaf extract at 150 mg/kg body weight effectively reduced ventricular myocyte hypertrophy in diabetic rats Conclusion: Red betel leaf extract significantly reduced ventricular myocyte hypertrophy but had no effect on fibrosis or intramyocyte lipid deposits.
ANTIBACTERIAL ACTIVITY TEST OF ETHANOL EXTRACT 70% OF FALOAK BARK (Sterculia quadrifida R.Br) ON Klebsiella Pneumoniae BACTERIA Shita Anggenella Dupe; Rr. Listyawati Nurina; Efrisca M. Br Damanik; Prisca Deviani Pakan
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.27147

Abstract

Introduction: Pneumonia is a common lower respiratory infection affecting all ages, caused by bacteria, viruses, fungi, or parasites. Klebsiella pneumoniae is a bacterial cause showing high antibiotic resistance, complicating treatment. As a result, alternative treatments using medicinal plants with antibacterial properties are needed. One promising plant is faloak (Sterculia quadrifida R.Br), traditionally used in herbal medicine and believed to have potential antibacterial effects worth further investigation. Methods: This study employed a true experimental method with a post-test only control group design. The treatment groups were given 70% ethanol extract of faloak bark at various concentrations (100%, 50%, 25%, 12.5%, 6.25%, and 3.12%). There were also a positive control group (meropenem antibiotic) and a negative control group (sterile distilled water). Data were analyzed using the Kruskal-Wallis test. Results: The 70% ethanol extract of faloak bark showed antibacterial activity against Klebsiella pneumoniae, with a significance value of p = 0.002 (< 0.05), indicating a significant difference in the inhibition zone diameters. Discussion: The extract demonstrated antibacterial properties and the ability to inhibit the growth of Klebsiella pneumoniae. Conclusion: The 70% ethanol extract of faloak bark (Sterculia quadrifida R.Br) exhibits antibacterial activity against Klebsiella pneumoniae.
Testing The Laxative Activity of Utasupe Leaf Juice from The Ende Region on White Rats (Rattus novergicus) Loperamid Induced Constipation Model Einstein Daud Victor Hendrik; Rr. Listyawati Nurina; Derri Tallo Manafe; Desi Indria Rini; Muhajirin Dean
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11608

Abstract

Constipation is a problem in the pattern of elimination due to the presence of dry or hard feces passing through the large intestine, while a laxative is a substance that can provide stimulation of intestinal peristalsis as a reflex of direct stimulation of the intestinal wall that can facilitate defecation. Many medicinal plants can treat constipation, one of which is Utasupe. Utasupe is a vegetable plant originating from the Ende region. In Ende, Utasupe is believed to facilitate bowel movements, so people often consume Utasupe. This study aims to determine the laxative effect of Utasupe leaf juice from Ende region on loperamide-induced male white rats (Rattus novergicus). The study was conducted experimentally on 30 Sprague daley strain white rats aged 8-12 weeks. The parameter for testing the laxative effect was the defecation pattern, while the observed parameter was the frequency of defecation every hour for 8 hours. Utasupe leaf juice was administered orally at a dose of 125 mg/mL, 250 mg/mL and 500 mg/mL, as a comparison negative control (Na-CMC) and positive control (Bisacodyl) were used. The results showed that the administration of Utasupe leaf juice at a dose of 250 mg/mL had a laxative effect on male white rats. Utasupe leaf juice has laxative activity in white rats (Rattus novergicus). The time required for defecation to occur after being given Utasupe leaf juice from the Ende area in white rats (Rattus novergicus) is one hour with the most effective dose is 250 mg/mL.
Co-Authors Alsen Diamel Oematan Anggraini, Thalitha Ayu Anita Amat Anita L. Shinta Amat Anita Lidesna Shinta Amat Aprio Ngga, Yoseph Mariano Arley Sadra Telussa Arley Telussa Cahyani Purnasari Christina Olly Lada Conrad L. H. Folamauk Damanik, Efrisca M. Br. Debora Shinta Liana Deri Riskiyanti Tallo Manafe Desi Indria Rini Desi Indriarini Efrisca M. Br Damanik Efrisca Meliyuita Br. Damanik Einstein Daud Victor Hendrik Elli Arsita Febrianti, Ika Fitriyah, Nur Laelatul Folamauk, Conrad L.H. Folamauk, Conrad Liab Hendricson Ginting, Almido Almido Haryanto Ginting, Almido H. Gregorius Kenang Widyantoro Handoyo, Nicholas E. Hewen, Wilhelmina W.M. Idawati Trisno Idawati Trisno Idawati Trisno Ika Febianti Buntoro Ika Febrianti Ikun, Elisabeth Sri Intan Indra Wardana, I Gede Aprilian Indriarini, Desi Kareri, Dyah Gita Rambu Kedang, Elisabeth Flora S. Klau, Maria Luz Clarita Koamesah, Sangguana M J Koamesah, Sangguana Marthen Jacobus Kolifa Ayu Wulansari Kote, Angel Eddelweist Yubertina Febrina Bida Lalandos, Jansen Loudwik Levina Sari Setianingrum, Elisabeth Luh Komang Ayu Shinta Dewi, Ni Manongga, Fidriati Olivia Maria Agnes Etty Dedy Mariana Archoon Sailana Mathias Nathaniel Kolobani Mory, Ogy Rya Muhajirin Dean Muntasir, Muntasir Nicholas Edwin Handoyo Nugraha, Rahmat Nurwan Nurul Fatmawati Pua Upa Paceli, Verena Pakan, Prisca D. PAKAN, PRISCA DEVIANI Pala, Maria Gemma Theovila Pao, Ressa Patricia Permatasari, Rr. Lilis Intan Prisca Deviani Pakan Prisca Deviani Pakan PRISCA DEVIANI PAKAN Rambu Kareri, Dyah Gita Ratu, Kristian Regaletha, Tadeus A. L. Riantoby, Raphaeline Murtiastari Riky Alberth Lerrick Rini, Desi Indria Riwu, Magdarita Rizqia Amanda Nafisah Nurawi Sagita, Sidarta Saka Pamukti Supriyadi Salean, Tjieci Yuniar Sangguana Marthen Jacobus Koamesah Sangguana Marthen Jacobus Koamesah Sare, Maria Claudya Nere Sari, Dewi Fadhilah Setianingrum, Elisabeth Levina Setiawan, I Made Buddy Shita Anggenella Dupe Sibero, Peniel Peranta Reynaldi Tarigan Sidauruk, Debora Maryke Idawati Sion Benu Sun, Diana Maximiliany Tadeus Andrea Lada Regaletha Tanto, Ayu Cyntia Turupadang, Welem Ullu, Arah Murni Adi Viviyanti Viviyanti Wahda Dwi Sari Wahyuningrum, Stefany Adi Woda, Rachel Rara Woda, Rahel Rara Wungouw, Herman P L