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All Journal African Multidisciplinary Journal of Sciences and Artificial Intelligence African Journal of Biochemistry and Molecular Biology Research African Journal of Sciences and Traditional Medicine Kwaghe International Journal of Sciences and Technology Kwaghe International Journal of Arts, Humanities and Religious Studies African Journal of Clinical Medicine and Pharmacy Research African Journal of Medicine, Surgery and Public Health Research
Isaac John Umaru
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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Generalized Anxiety Disorder (GAD): Understanding Its Roots, Impact, and Modern Approaches to Treatment Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammed Al-Musawi
Kwaghe International Journal of Sciences and Technology Vol 2 No 2 (2025): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v2i2.5668

Abstract

Chronic worry and anxiety about particular areas of functioning or life shifts Characterizes GAD. Generalized anxiety disorder GAD remains one among the most widespread and enduring forms of anxiety disorder. GAD doesn’t arise out of thin air, but is often associated with deeper, systematic issues at hand. Not only does GAD affect one neurologically, but it impacts their emotional, social, and occupational functionality. Globally, millions face GAD. Furthermore, unlike anxiety regarding day-to-day things, GAD has no identifiable ‘weakness’ that triggers it, making it chronic in nature and extremely hard to control without professional support. In this article, I will aims towards incorporating the important aspects of GAD exploring its headline causes, diagnostic rules, prominent face, and fusion of treatment including modern medicine alongside proactive methods like exercise, psychotherapy, and self-help programs. Primarily focus is laid on CBT alongside mindfulness approaches, innovation due to neurobiology in treatment, and neurobiology’s impact on understanding and eradicating illness.
Major Depressive Disorder (MDD): A Multifactorial Mental Health Crisis and Approaches to Holistic Management Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammed Al-Musawi
Kwaghe International Journal of Sciences and Technology Vol 2 No 2 (2025): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v2i2.5670

Abstract

MDD, also known as Major Depressive Disorder, or clinical depression, is one of the most common and debilitating mental illnesses worldwide since it affects a person’s emotional, cognitive, and physiological functioning balance. Sufferers typically experience unrelenting low mood, anhedonia or lack of interest in activities, extreme tiredness, and numerous loopy mental and physical symptoms that negatively affect normal functioning. It’s worth emphasizing that a complex disorder, not solely an emotional state, depression arises as a result of the interplay of genetics, predisposition to the illness, neurobiological underpinnings, psychosocial and environmental stressors, as well as their myriad factors. This paper analyzes the causes, symptoms, diagnostic guidelines, and the most recent methods of treatment available for MDD. Special focus is given to psychotherapy, pharmacologic approaches, lifestyle changes, and the necessity for a holistic approach that integrates all dimensions of patient care.
Modern Microbiology: Exploring Microbial Frontiers in Health, Environment, and Biotechnology Muhammad Akram; Isaac John Umaru; Abid Mahmood; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; , Jaouher Ben Ali; Jehan Mohammed Al-Musawi
Kwaghe International Journal of Sciences and Technology Vol 2 No 2 (2025): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v2i2.5818

Abstract

Microbiology, the study of microscopic organisms including bacteria, viruses, fungi, archaea, and protozoa, remains one of the most dynamic and transformative disciplines in modern science. It is foundational to understanding diverse biological systems, from molecular genetics to ecosystem function, and is integral to advancements in biotechnology, medicine, and environmental science. The field has expanded significantly with the advent of molecular biology and omics technologies, enabling precise exploration of microbial genetics, physiology, and metabolic networks. Microorganisms, while recognized as agents of disease, are also vital for global biogeochemical cycles, nutrient turnover, and ecological resilience. Recent decades have seen a surge in interest driven by the emergence of antibiotic resistance, the global burden of infectious diseases, and the need to decode host microbe interactions. Innovations such as next generation sequencing, metagenomics, and single cell analysis have redefined microbial ecology by revealing the complexity and ubiquity of unculturable microbial communities across environments—from the human gut microbiota to extreme ecosystems like deep sea hydrothermal vents. Simultaneously, the rise of synthetic biology and microbial bioengineering has paved the way for novel applications in sustainable energy, environmental remediation, and industrial biotechnology. Particularly, the human microbiome has emerged as a frontier linking microbial diversity to immunity, metabolic health, and neurodevelopmental outcomes. As microbiology increasingly converges with computational biology, nanotechnology, and systems medicine, it is poised to offer transformative solutions to global challenges in health, food security, and environmental sustainability. This overview synthesizes the current landscape of microbiological research, spotlighting core concepts and emerging directions that define the field’s evolution.
Sukur Kingdom: The Sleeping Beauty (Popularizing Nigeria’s 1st UNESCO World Heritage Site) Oluwasegun M. Oladimeji; Isaac John Umaru
Kwaghe International Journal of Arts, Humanities and Religious Studies Vol 1 No 1 (2024): Kwaghe International Journal of Arts, Humanities and Religious Studies
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijahrs.v1i1.4077

Abstract

The Sukur Kingdom, located in Madagali Local Government Area of Adamawa State, Nigeria, is recognized as a UNESCO World Heritage Site for its unique cultural landscape, ancient iron smelting technology, and terraced fields. Despite its historical significance, the site remains largely unknown to the global and local audience. This paper seeks to explore the cultural, historical, and geographical attributes of the Sukur Kingdom, examining its potential as a key tourist attraction. By identifying the challenges facing its promotion, this article proposes strategies for popularizing the site while preserving its heritage.
The Effects of Sleep Deprivation on Mental and Physical Health Muhammad Akram; Isaac John Umaru; Nosheen Aslam; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Abid Rashid; Jehan Mohammed Al-Musawi; Abid Mahmood
Kwaghe International Journal of Sciences and Technology Vol 2 No 2 (2025): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v2i2.6248

Abstract

Sleep is a complex, restorative, and multi-stage process essential for maintaining physical health, emotional regulation, and cognitive functioning. Beyond mere rest, sleep supports vital biological functions that sustain overall well-being. However, in today’s fast-paced society, social interactions, work demands, and excessive screen time frequently take precedence over adequate sleep, leading to widespread sleep deficiency. This phenomenon, commonly referred to as sleep deprivation, is increasingly prevalent, particularly in developing countries where technological advancement, occupational pressures, and lifestyle factors disrupt natural sleep-wake cycles. This article examines the causes and consequences of insufficient sleep, exploring the underlying biological mechanisms and their impact on cardiovascular health, immune system function, mental health, memory, and quality of life. Additionally, it underscores the importance of proper sleep hygiene and presents strategies to improve sleep patterns across all age groups, aiming to mitigate the adverse effects of sleep loss and promote holistic health.
Mental Health Awareness: Breaking the Stigma Muhammad Akram; Sabahat Abbas; Isaac John Umaru
Kwaghe International Journal of Arts, Humanities and Religious Studies Vol 2 No 2 (2025): Kwaghe International Journal of Arts, Humanities and Religious Studies
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijahrs.v2i2.5267

Abstract

Mental health remains a vital component of an individual’s overall health which is often stigmatized and prevents people from receiving the help they need. The stigma is perpetuated through deeply ingrained misunderstandings, social alienation, and systemic obstacles that make it necessary to focus on the promotion of education, advocacy, and reforms. Education helps achieve the difficult task of addressing stereotypes and promoting empathy and normalization of mental health awareness advocates in for enhanced access to care, funding, and policy support. Initiatives by the community and responsible media portrayals aid in changing perceptions in the public which helps people seek the help they need without being judged. Thus, the more the stigma is conquered concerning mental health the more positive and supportive environment is created which helps in improving the society’s overall mental health and life quality.
The Effect of Social Media on Mental Wellbeing: The Good and the Bad Muhammad Akram; Isaac John Umaru; Nosheen Aslam; Mohammed Khudhair Hasan; Hind A. Abdulghafoor; Fahad Said Khan; Fethi Ahmet Ozdemir; Gaweł Sołowski; Jaouher Ben Ali; Jehan Mohammed Al-Musawi; Abid Mahmood
Kwaghe International Journal of Arts, Humanities and Religious Studies Vol 2 No 2 (2025): Kwaghe International Journal of Arts, Humanities and Religious Studies
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijahrs.v2i2.6246

Abstract

Social media has evolved into a central platform for interpersonal communication and a powerful source of information within contemporary culture. While earlier generations were less accustomed to integrating technology and social media into daily life, current users actively embrace these platforms. Beyond facilitating social connections and networking opportunities, social media also serves as a tool for raising awareness and promoting various causes. However, these benefits are counterbalanced by potential negative effects on users’ emotional well-being. This paper critically examines the impact of social media on mental health, focusing on issues such as social media addiction, anxiety, depression, and self-esteem. It explores how excessive media use and social comparison contribute to psychological distress, highlighting the importance of user responsibility. Ultimately, the discussion advocates for a balanced approach to social media engagement that safeguards mental health while leveraging its positive potentials.
Understanding Modern Nanotechnology: Insights into Its Evolution, Applications, and Global Impact Umme Laila; Muhammad Akram; Fahad Said Khan; Fethi Ahmet Ozdemir; Isaac John Umaru
Kwaghe International Journal of Sciences and Technology Vol 2 No 2 (2025): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v2i2.6622

Abstract

Nanoparticles, or ultrafine particles, are defined as particles with diameters ranging from 1 to 100 nanometers. As the core units of nanotechnology, these structures serve as the building blocks for integrating nanoscale materials into larger, functional systems. Over the past decade, nanotechnology has emerged as a transformative and interdisciplinary field, bridging advancements across a broad spectrum of domains, including medicine, materials science, energy, mechanics, plastics, optics, electronics, and aerospace. This paper provides an overview of the fundamental principles of nanotechnology, explores the unique properties of nanostructures, and highlights their current and potential applications across various scientific and industrial disciplines. By examining both foundational knowledge and emerging innovations, the study underscores nanotechnology’s expanding role in addressing complex challenges and shaping future technological development.
Lucifer as Morning Star: A Theological and Linguistic Analysis of 2 Peter 1:19 Isaac John Umaru
Kwaghe International Journal of Arts, Humanities and Religious Studies Vol 2 No 3 (2025): Kwaghe International Journal of Arts, Humanities and Religious Studies
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijahrs.v2i3.8019

Abstract

This study offers a critical examination of the term Lucifer in 2 Peter 1:19, challenging its conventional association with Satan by analysing its linguistic, theological, and historical dimensions. While Lucifer has become synonymous with the fallen angel in Christian tradition—primarily through its use in Isaiah 14:12 in the Latin Vulgate—its appearance in 2 Peter reflects a distinct and positive symbolism. Derived from the Greek word phōsphoros, meaning “light-bringer” or “morning star,” Lucifer in this Petrine context functions as a metaphor for Jesus Christ, whose spiritual illumination rises within the hearts of believers as a sign of eschatological hope. Through a comparative analysis of biblical texts, classical Latin usage, and patristic commentary, the paper demonstrates that the term Lucifer in 2 Peter was never intended to denote evil. Jerome’s translation in the Vulgate aligns with classical Latin conventions, where lucifer referred to Venus as the morning star, a symbol of light and renewal. Church Fathers such as Origen and Jerome themselves acknowledged this Christological reading and distinguished it from the polemical interpretation found in Isaiah. Modern scholarship further supports this view by emphasizing the apocalyptic and transformative imagery embedded in the verse. By disentangling the semantic evolution of Lucifer and situating it within its proper exegetical framework, this study reclaims its original theological intent and argues that Lucifer in 2 Peter 1:19 represents not a demonic figure, but the radiant presence of Christ guiding believers through spiritual darkness toward divine revelation. This reevaluation contributes to broader discussions on biblical translation, doctrinal development, and the symbolic language of Christian eschatology.
Effect of Methanol Leaf Extract of Annona senegalensis on Liver Function in Diethylnitrosamine-Induced Hepatocellular Carcinoma in Rats and Its Potential as an Antibacterial Agent Isaac John Umaru; Mary Athanasius Udoh; Etah Hope Mona; Mosugu Ovayoza Omolara; Ogar Fonne Okang; Ingwu Joseph Akem; Akafa Andes Tansaba; Shadrach Philip; Otashu Kenneth Frank
Kwaghe International Journal of Sciences and Technology Vol 2 No 3 (2025): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v2i3.7362

Abstract

Hepatocellular carcinoma (HCC) is among the most prevalent and deadly cancers globally, with limited treatment options and poor prognosis in advanced stages. This study evaluated the therapeutic potential of methanol leaf extract of Annona senegalensis against diethylnitrosamine (DEN)-induced HCC in Wistar rats and investigated its antibacterial properties. Thirty-six male albino rats were allocated into six groups: Group I (normal control) received no treatment; Group II (negative control) was induced with HCC using DEN (50 mg/kg b.w., intraperitoneally) weekly for three weeks without therapy; Group III (positive control) received DEN followed by silymarin (100 mg/kg b.w.); while Groups IV, V, and VI received DEN followed by A. senegalensis extract at 200, 400, and 600 mg/kg b.w., respectively, administered orally for 14 days. Biochemical analysis showed that the extract significantly (p < 0.05) ameliorated DEN-induced hepatotoxicity, with the 400 mg/kg dose most effective in reducing AST (48.71 ± 1.21 IU/L) and ALT (20.74 ± 1.06 IU/L) compared to the negative control (69.52 ± 0.88 IU/L and 54.97 ± 1.54 IU/L, respectively). Hepatic synthetic function was restored, as indicated by increased total protein (6.37 ± 0.13 g/L) and albumin (5.11 ± 0.10 g/L). Histopathological analysis confirmed marked architectural recovery with reduced necrosis and inflammatory infiltration. The extract also demonstrated significant antibacterial activity, exhibiting dose-dependent inhibition zones against Gram-positive (Staphylococcus aureus, Bacillus subtilis) and Gram-negative (Escherichia coli, Pseudomonas aeruginosa) bacteria, with effects comparable to standard antibiotics. These findings suggest that A. senegalensis leaf extract exerts hepatoprotective effects—likely through antioxidant, anti-inflammatory, and antiproliferative mechanisms—while also offering broad-spectrum antimicrobial benefits. The 400 mg/kg dose emerged as the most effective, highlighting its promise as a cost-effective complementary therapy for managing HCC and bacterial infections, particularly in resource-constrained settings. Further research should focus on isolating and characterizing the bioactive compounds and elucidating their mechanisms of action.
Co-Authors , Jaouher Ben Ali A. J. Amuda Abdul Wadood Chishti Abdullahi Sa’adu Adeseye Abdulmumin Jabir Abid Mahmood Abid Rashid Abimbola Gbenga Olayemi Abimbola Gbenga Olayeni Aboki Nwunuji Mijinyawa Abu Michael Sunday Abubakar Aisami Adeseye Helen Oluwabunmi Adetoyi Moses Gbadebo Adeyanju Kate Yemisi Agbo Chibuike Ekunyi Agbo Christiana Onyindia Ahmad Alhassan Siddan Ajala-Lawal R. A Ajiduku Leyoa Abershi Akafa Andes Tansaba Akafa Andes Tensaba Akoh Miracle Talent Akpan Usenobong Morgan Alam Afroz Urooj Khan Ale Ebenezer Morayo Alice Njolke Mafe Aliyu Olamilekan Najeeb Ameh Godwin Okwori Amna Javed Ananias Amen Anih David Chinonso Anthony Mishara Audu Arowora K. A Arowora K. A. Arowora Kayode Arowora Kayode Adebisi Artu Ishishen John Ashaka Fidelis Utioukpan Atsu Ayi Augustine Absalom Bakari Genevieve Sirina Bando Christopher David Bemhemba Iba Benjamin Nanisi Daniel Bilyaminu Habibu Chabunda Endashi Esseyi Chakfa Nanmar Charles Ayara Chinedu Christian Iheanacho Chukuma Stephen Ezeonu Dafup Kadel Istifanus Dafup Katdel Istifanus Daniel Konka Danjuma Janya Danladi Mbosire Peter Danlami Efoseh David Christopher Bando David Umahi Dawoye Yusufu Debora Akinola Umogbai dulrashid Dauda Maianguwa Ebenezer Morayo Ale Edom Favour Ogochukwu Egbeadumah Maryanne Odufa Egeonu Stephen Ugoeze Eisa Yazeed Ghazwani Eluu Emmanuel Chukwudi Emmanuel Alooma Emmanuel Askeb-nde Joel Emmanuel Askebnde Joel Emmanuel Chikodiri Okoli Emmanuel Efongwa Emmanuel Eluu Chukwudi Emmanuel Olofu Omanchi Emmanuel Omanchi Eric Agim Agaba Etah Hope Mona Evelyn Ovenomo Tony-Enwin Ezeonu C. S Ezugwu Hilary Chikata Fahad Said Khan Favour Joel Bafai Fethi Ahmet Ozdemi Fethi Ahmet Ozdemir Fidelis Okii Ekpo Gabriel Favour Chisom Gaweł Sołowski Genevieve A. Yeboah Genevieve Akpah Yeboah George Okra Hassan Gideon Likida Tiimob Gift Amofa Gloria Omonefe Oladele Gomba Victoria Eno Habiba Idris Adam Haleema Sadia Hauwa A. Umaru Helen Oluwabunmi Hind A. Abdulghafoor Ibrahim Jamilat Mijinyawa Idris Habiba Adams Ikrimah Usman Mohammed Ikwebe Joseph Imo Chinedu Inemesit Samuel Essien Ingwu Joseph Akem Ingwu Joseph Akem3 Iornenge Terungwa Joseph Isaac Eleojo Shaibu Isbah Shahid Iseko Iyoko Kingsly Ismail Yunusa Yuguda Izam Emmanuel David Jackson Soyinka Malantso James Agbu Sunday James Eneji Agwu Jankada Patience Audu Janya Danjuma Jaouher Ben Ali Jehan Mohammad Al-Musawi Jehan Mohammed Al-Musawi Jehan Mohammed Jehan Mohammed Al-Musawi Jibaniya Grace Mchibuma Joanna Afariba Johnson John Odiba Oko Joseph Oteng Josephine Maina Sule Julius Ishaya Salman Kaka Garpiya Yakubu Katchim Evelyn Shadrach Katchin Evelyn Shadrach Kerenhappuch Isaac Umar Kerenhappuch Isaac Umaru Khalid Yahuza Abbas Kingsley Bassey Enang Kingsley Iyoko Iseko Kwabena Owusu Amoah Kyugah Jacob Tersur Lawal Danjuma Tyem Lawal Favour Enyojo Lazaru Joseph Goje Lipana Dorcas Bappa Lubabatu Abdulrasheed Maayam Usman Ahmed Mai-anguwa Abdulrashid Dauda Maianguwa Abdulrashid Dauda Maianguwa Abdulrsashid Dauda Manasseh Ilumunter Matilda Mary Athanasius Udoh Maryam Usman Ahmed Mathew Jacob Mathias Mawuli Ametefe Mgbede Timothy Michael S. Abu Michael Sunday Abu Misbah Ahmed Mohammed Khudhair Hasan Momina Iftikhar Moses Adondua Abah Mosugu O. O Mosugu Ovayoza Omolara Muhammad Abdullah Muhammad Akram Muhammad Bashir Muhammad Muhammad Haris Baig Muhammad Tayyab Aslam Muhammad Zuhairah Ismail Musa Azegya Mustapha Musbau Adekunle Yahaya Nanyak Zingfa Galam Nasiru Audu Ngabea Nkechi Gift Ijeomah Nkiri Annasthesia Ekubnse Nosheen Aslam Nurudeen Umar Abdulkadir Nwachukwu Favour Onyinyechi Nwofor Innocent Obadiah Saveni Yusuf Oche Williams Ujah Ocheifa Mathew Ngbede Ocheifa Matthew Ngbede Odok Endurance Akam Ogar Fonne Okang Ogholo Ogholo Ekup Ojochenemi E. Yakubu Ojochenemi Ejeh Yakubu Okoli Emmanuel Okpanachi Nuhu Oyibo Okrah George Hassan Olabanji Martina Morolake Olawale Otitoju Oluwasegun M. Oladimeji Omachi Blessing John Onwubiko A. Henry Onwubiko N. Grace Otashu Kenneth Frank Otitoju Olawale Otitoju Oluwale Otitujo Olawale Ozzioma Praise Acha Panah Philemon Peter Ise Uduak Precious Chioma Jack Prince Kwadwo Gyasi Prince Osei Akumia Prosper Uneju Peter Queen Uyo Williams Rashida Ismail Mohammed Sabahat Abbas Samuel Tamunoiyowuna Cockeye Brown Selumun Solomon Ipav Shadrach Philip Shelter Agbeko Bobie Shitta Nasisi Namuma Simon Teza Zinas Solomon Chuanu Solomon Godiya Marvelous Solomon O. Asare Solomon Ossom Asare Steve Osagie Asuelimen Sukyakma Manu Sulaiman Abubakar Aliyu Sule John Ugbedeojo Tahmina Maqbool Tensaba Andes Akafa Tongle Nanle John Tsokwa Punarimam Rebecca Tyem Lawal Danjuma Ubur Terzulum Wilson Ugwuala Chimaobi Melvin Ugwuoke Kenneth C Umme Laila Urooj Rehman Usenobong Morgan Akpan Usman Ikira Usman Lukman Adamu Victor Duniya Sheneni Victor Makanjuola Victoria Ifeoluwa Ayo Vika Tensaba Akafa Williams Oche Ujah Wisdom L. Benjamin Yakubu Ojochenemi Ejeh Zainab Bello Dambazau Zephaniah Hananiah Shenia