Article Per Year (5 Year)
p-Index From 2021 - 2026
5.73
P-Index
This Author published in this journals
All Journal E-Jurnal Medika Udayana JSEH (Jurnal Sosial Ekonomi dan Humaniora) Jurnal Kedokteran Pharmascience JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Biologi Tropis SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Pengabdian Magister Pendidikan IPA Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Kesehatan Tambusai Sasambo Journal of Pharmacy INDRA: Jurnal Pengabdian kepada Masyarakat Jurnal Pepadu Jurnal Sains dan Kesehatan
Hidayati, Agriana Rosmalina
Fakultas Kedokteran Universitas Mataram
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 42 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 42 Documents
Search

 1   2   3   4   5 
Anifungi Activity Test of Ethanoled Extract of Cashew Gua Leaves (Anacardium occidentale) Against Candida albicans Yunita, Yunita; Hidayati, Agriana Rosmalina; Hajrin, Wahida
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7402

Abstract

Cashew leaves (Western cashew) contains compounds belonging to the class of flavonoids, tannins, and saponins which are thought to have antifungal activity against Candida albicans. This study aims to determine the antifungal activity of the ethanol extract of cashew leaves on growth Candida albicans based on the inhibition zone formed. The method for determining antifungal activity was carried out through disc diffusion. Cashew leaf extract was made into three different concentrations namely, 5%, 7.5%, and 10%, the negative control used 10% DMSO, and 2% ketoconazole as a positive control. Based on the results of the phytochemical screening, the ethanol extract of cashew leaves contains compounds belonging to the class of flavonoids, tannins and saponins. The results of the antifungal activity test of the ethanol extract of cashew leaves at concentrations of 5%, 7.5%, and 10% could inhibit the growth Candida albicans with the diameter of the inhibition zone respectively, 10.35 mm, 11.93 mm, 14.12 mm. The diameter of the inhibition zone on ketoconazole was 21.75 mm and no inhibition zone was formed in the negative control group. From the results of the study it was concluded that the ethanol extract of cashew leaves has activity against Candida albicans.
Standardization of Specific and Non-Specific Parameters of Methanol Extract from Poinsettia Red Leaves (Euphorbia pulcherrima Willd.) Abdillah, Lalu Khairi; Hanifa, Nisa Isneni; Mukhlishah, Neneng Rachmalia Izzatul; Hidayati, Agriana Rosmalina
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7412

Abstract

The poinsettia red leaves (Euphorbia pulcherrima Willd.) have the potential as antibacterial and antioxidant agents and are widely utilized by the community for wound healing purposes. This research aims to determine the specific and non-specific parameter values of methanol extract from poinsettia red leaves. Samples of poinsettia red leaves were processed into extracts using the maceration method with 96% methanol as the solvent. The extract was standardized by determining specific and non-specific parameters. The test result data were analyzed descriptively in both qualitative and quantitative manners. The standardization results of specific parameters showed the identity of the extract as methanol extract of poinsettia red leaves, with organoleptic properties of a thick greenish-black extract, distinctive poinsettia aroma, and bitter taste. The water-soluble compound content was 51,47% ± 0,437 and ethanol-soluble 61,22% ± 0,117. Results for non-specific parameters indicated drying loss of 12,50% ± 0,419, moisture content of 12,62% ± 0,173, total ash content of 5,25% ± 0,538, acid-insoluble ash of 0,34% ± 0,048, residual solvent 0,00% ± 0,000, total plate count was TFTC (Too Few To Count), and mold and yeast count was 1,5 x 104 colonies/g sample. This research can serve as a reference for determining specific and non-specific parameters of methanol extract from poinsettia red leaves.
Effect of Solvent Extraction on Yield and Phytochemical Screening of Kedondong (Spondias dulcis) Leaf Extracts Zahra, Nisrina; Mukhlishah, Neneng Rachmalia Izzatul; Hidayati, Agriana Rosmalina
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7465

Abstract

Kedondong (Spondias dulcis) is empirically used as a cough medicine, skin pain, burns, and antimicrobials. in addition, the people of Kembang Paseban Village, Mersam Subdistrict, Batanghari District, Jambi Province use kedondong leaves as a barut medicine (birth patch medicine). The pharmacological activity of kedondong leaf extract is as a wound healer, antibacterial, anti-inflammatory, antifungal, antipyretic, and as a larvicide. The yield value greatly affects the amount of bioactive content contained in the extract and can affect the results of phytochemical screening. The purpose of this study was to determine the effect of solvent comparison on yield and phytochemical screening of ethyl acetate extract of kedondong leaves. The method used in this study was sonication with a solvent ratio of 1:5 and 1:10, the temperature and time used were 35oC and 30 minutes. The results obtained in the ratio of 1:5 obtained a higher % yield of 5.53% compared to the solvent ratio of 1:10 of 4.67%. While the metabolite compounds identified from ethyl acetate extract are flavonoids and alkaloids.
Article Review: Pharmacological Activities of Renggak Plant (Amomum dealbatum Roxb.) Cahyani, Dina Fathia; Hidayati, Agriana Rosmalina
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7599

Abstract

The renggak plant (Amomum dealbatum Roxb.) is a native plant of Lombok Island that belongs to the Zingiberaceae family and is traditionally used as a remedy for coughs, diarrhea, arthritis, and eye washes. Ethanol extract from the renggak fruit is reported to contain secondary metabolites such as flavonoids, tannins, terpenoids, alkaloids, steroids, saponins, polyphenols, and several other types of fatty acids, which have various pharmacological activities. This review article aims to provide information on the various pharmacological activities of the renggak plant, including antidiabetic, antiurease, antioxidant, antibacterial, and antifungal activities. The method used in this article is a systematic review of various literature sources. Articles were collected using the Google Scholar and PubMed databases with keywords such as Renggak, Amomum dealbatum Roxb., and pharmacological activities. Based on the data results, it can be concluded that the renggak plant (Amomum dealbatum Roxb.) exhibits pharmacological activities as an antidiabetic, antiurease, antibacterial, antioxidant, and antifungal agent.
Anti-Radical Activity Test of Fractions from Ashitaba Herbs (Angelica keiskei) Permatasari, Ni Made Ayu Dinda; Muliasari, Handa; Hanifa, Nisa Isneni; Hidayati, Agriana Rosmalina; Hidajat, Dedianto; Hajrin, Wahida; Rizkika, Adila
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7638

Abstract

Acne vulgaris is a chronic inflammation of the skin’s pilosebaceous unit, caused by oxidative stress due to reactive oxygen species (ROS) release. Oxidative stress conditions can be treated using natural antioxidants, namely ashitaba (Angelica keiskei). In contrast to previous studies that tested column chromatography fraction of the macerated ethanol extract, this study examined the liquid-liquid partition fraction of 80% methanol sonicated extract of Ashitaba herb. This study aims to determine the antiradical activity of various fractions of Ashitaba herb extract against 1,1-diphenyl-2-picrylhidrazyl (DPPH) free radicals. 80% methanol extract of the Ashitaba herb was fractionated using chloroform, ethyl acetate, and water solvents. Each ashitaba herb fraction was identified for the content of flavonoids and phenolic compounds and the antiradical DPPH activity was tested with ascorbic acid standard using a UV-Vis spectrophotometer. The IC50 value of each fraction was statistically analyzed using One-Way ANOVA and Posthoc Tukey. The results of phytochemical identification showed that ashitaba herb fractions positively contain flavonoids and phenolics. Antiradical activity of the chloroform, ethyl acetate, and water fractions against DPPH was indicated by IC50 values of 164.22±5.68 ppm (moderate); 8.70±0.12 ppm (very strong); and 243.60±8.14 ppm (weak). Statistically, each ashitaba herb fraction differed significantly from ascorbic acid (IC50 2.37±0.05 ppm). The ethyl acetate fraction has the strongest antioxidant activity and is in the same category of antioxidant strength as the ascorbic acid standard.
Determination of Total Flavonoid Content and Antioxidant Activity of Avocado Stem Bark (Persea americana Mill) Ethanol Extract in Inhibiting DPPH Risnata, Richa Poetri; Hidayati, Agriana Rosmalina
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7776

Abstract

Excessive free radicals in the body can trigger degenerative diseases. Therefore, antioxidant help is needed from outside the body to inhibit free radicals. Long-term use of synthetic antioxidants is limited because they can cause cancer. This encourages the development of natural antioxidants, one of which comes from avocado stem bark. Avocado stem bark contains flavonoids which act as antioxidants. This study aims to determine the total flavonoid content and antioxidant activity of avocado stem bark ethanol extract in inhibiting DPPH. Avocado stem bark was extracted using sonication followed by the identification of flavonoids using a tube test and thin layer chromatography test. Determination of total flavonoid content was carried out using the colorimetric method and antioxidant testing using the DPPH method. The results obtained were that the avocado stem bark was positive for containing flavonoids based on tube tests and thin layer chromatography. The results of determining the flavonoid content in the ethanol extract of avocado stem bark were 5.572 mgQE/g. The ethanol extract of avocado stem bark is a very strong antioxidant with an IC50 of 21.221 ppm. So it was concluded that avocado stem bark can be used as a natural antioxidant candidate.
Formulation and Evaluation of Moringa Leaf Ethanol Extract Emulgel and its Effectiveness Test Against Staphylococcus aureus Raissa, Talitha Hasna; Pratiwi, Eskarani Tri; Hidayati, Agriana Rosmalina
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8218

Abstract

Moringa leaves (Moringa oleifera Lamk.) have Tannin compounds which are secondary metabolites as antibacterial. The purpose of this study is to determine the antibacterial properties of ethanol extract from moringa leaves against Staphylococcus aureus. The research methods began with the extraction of Moringa leaves using sonication with 96% ethanol as the solvent, followed by testing the antibacterial effectiveness of the extract at concentrations of 5%, 10%, and 20%. The extract concentration with the best inhibition zone diameter was formulated into an emulgel, followed by physical evaluation of the formulation and testing its effectiveness against Staphylococcus aureus. The bacterial inhibition zone was measured to determine the antibacterial level of the extract and emulgel formulation. The results of antibacterial effectiveness were evaluated using the One Way ANOVA test with a confidence level of 95%. The yield of the extract was found to be 13.05%. The inhibition zone diameters for the ethanol extract of Moringa leaves at concentrations of 5%, 10%, and 20% were 4.8 mm, 5.3 mm, and 8.1 mm, respectively. The physical evaluation of the ethanol extract emulgel formulation met the criteria for a good emulgel. The emulgel containing 4% ethanol extract from Moringa leaves produced an inhibition zone diameter of 4.8 mm, indicating weak antibacterial effectiveness. There was a significant difference between the treatment groups according to the results of the One Way ANOVA test with a significance value (p=0.000). This study found that Moringa oleifera leaf ethanol extract has the ability as an antibacterial; however, its effectiveness decreases when formulated into an emulgel, likely due to the reduction in extract concentration in the final formulation.
DPPH Radical Capture Test of Sumbawa Oil and Identification of Compound Content Using GC-MS Wardani, Ray Haerul; Permatasari, Lina; Hidayati, Agriana Rosmalina; Hanifa, Nisa Isneni
Jurnal Biologi Tropis Vol. 25 No. 1 (2025): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i1.8468

Abstract

Free radicals are reactive fragments that can trigger a variety of chronic diseases. Antioxidant compounds are needed to counteract the attack of free radicals. Sumbawa oil is one of the natural traditional remedies that has the potential to be a natural antioxidant because it contains compounds such as lauric acid, palmitic acid, linoleic acid, stearic acid, and methyl palmitate. The study aimed to determine the metabolite compounds contained in the Sumbawa oil brand “Rimba” and their activity to capture the DPPH free radical. The Sumbawa oil determined their metabolite compounds using Gass Chromatography-Mass Spectrometry (GC-MS). The antioxidant activity of Sumbawa oil was analyzed using the DPPH radical capture method. The GC spectra showed the 5 compounds detected in the Sumbawa oil. In addition, the MS spectra showed these 5 compounds were delta-3-carene, trans-caryophyllene, palmitic acid, palmitoleic acid, and stearic acid. The antioxidant activity of Sumbawa oil was found to be very weak with an IC50 value of 13.49 ± 0.34 mg/mL. Therefore, Palmitoleic acid and palmitic acid were reported to have potential antioxidant activity. These compounds were lipophilic antioxidants that did not properly detect their antioxidant activity using the DPPH method. So, the antioxidant activity of Sumbawa oil was recommended to be analyzed using the β-carotene bleaching method.
ARITMIA: AKTIVITAS BERMAIN TINGKATKAN KINERJA SIVITAS AKADEMIKA PROGRAM STUDI FARMASI UNIVERSITAS MATARAM Puspitasari, Candra Eka; Hidayati, Agriana Rosmalina; Ariani, Fitri; Sunarwidhi, Anggit L.; Aini, Siti Rahmatul; Pratama, Iman Surya; Pujiarohman, Pujiarohman; Agustini, Nur Indah
Jurnal Pepadu Vol 5 No 2 (2024): Jurnal PEPADU
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/pepadu.v5i2.4065

Abstract

Perguruan tinggi dalam menjalankan aktivitas profesional dibidang pendidikan tidak terlepas dari peran dosen dan tenaga pendidik. Program Studi Farmasi Universitas Mataram merupakan salah satu Perguruan Tinggi Negeri yang bersinergi dalam meningkatkan mutu akademika. Dalam rangka melaksanakan fungsi dan peran yang profesional, diperlukan strategi untuk meningkatkan kualitas kerja dosen dan tenaga pendidik. Kegiatan ini diselenggarakan dengan tujuan meningkatkan kualitas kerja serta kekompakan dosen dan tenaga pendidik dengan memberikan training melalui games secara berkelompok. Kegiatan yang telah terselenggara berjalan dengan baik yang ditunjukkan oleh adanya kerja sama, kekompakkan, kepemimpinan, kepercayaan, kejujuran, kreativitas, dan kemampuan mendengarkan pendapat antar peserta. Selanjutnya, pasca kegiatan nampak adanya peningkatan kekompakan dan kualitas kerja SDM.
LITERATUR REVIEW: AKTIVITAS FARMAKOLOGIS, METABOLIT SEKUNDER, POTENSI 4-HIDROKSIDERISIN DAN XANTOANGELOL ASHITABA SEBAGAI ANTIBIOTIK, ANTIINFLAMASI, ANTIOKSIDAN UNTUK PENYEMBUHAN JERAWAT Riadi, Putri Oktaviati; Hidayati, Agriana Rosmalina; Muliasari, Handa
Jurnal Kesehatan Tambusai Vol. 5 No. 1 (2024): MARET 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i1.25921

Abstract

Akne vulgaris (AV) atau jerawat merupakan kondisi peradangan menahun unit pilosebasea dengan gambaran klinis biasanya polimorfik yang terdiri atas berbagai kelainan kulit berupa: komedo, papul, pustul, nodul, dan jaringan parut. AV dapat sembuh sendiri (Self limited disease). AV memiliki banyak penyebab, yaitu faktor genetik, ras, makanan, iklim, kebersihan kulit, penggunaan dan pemilihan kosmetik, serta faktor kejiwaan atau kelelahan. Tata laksana pengobatan jerawat umumnya menggunakan antibiotik yang dapat menghambat inflamasi, membunuh bakteri dan antioksidan mampu membantu jerawat lebih cepat sembuh serta mencegah kerusakan kulit lebih lanjut. Ashitaba (Angelica keiskei) merupakan tanaman tradisional dari Jepang, mengandung kalkon yang melimpah. Kandungan kalkon dari ashitaba yaitu 4-hidroksiderisin (4-HD) dan xantoangelol (XAG) menunjukkan bioaktivitas seperti antibakteri, antikanker, antiinflamasi, antioksidan dan antidiabetes. Metabolit sekunder lain yang terkandung dalam ashitaba antara lain alkaloid, triterpenoid, saponin, steroid dan glikosida. Literatur Review ini bertujuan untuk mengetahui metabolit sekunder dan aktivitas farmakologis sebagai antibiotik, antiinflamasi, serta antijerawat untuk Penyembuhan jerawat ashitaba terutama pada senyawa 4-hidroksiderisin dan Xantoangelol. Metode yang digunakan dalam penulisan artikel ini yaitu dengan mengumpulkan berbagai sumber berupa pustaka primer, sekunder, dan tersier.. Database yang digunakan yaitu Google Scholar, dan PubMed. Literatur yang digunakan terdiri dari dua bahasa, yaitu bahasa Inggris dan bahasa Indonesia. Berdasarkan hasil data literatur, dapat disimpulkan bahwa kandungan kalkon yaitu 4-hidroksiderisin dan Xantoangelol tanaman ashitaba (Angelica keiskei) memiliki aktivitas farmakologis sebagai agen antibakteri, antiinflamasi dan antioksidan, sehingga dapat digunakan sebagai alternatif pengobatan jerawat.
Co-Authors Abdillah, Lalu Khairi Achmad Fuad Hafid Agustini, Nur Indah Aini, Siti Rahmatul Aliefman Hakim Amira Amira Amni Hamid Anggit L. Sunarwidhi Anggit Listyacahyani Sunarwidhi Anindiya, Naya Wahyu Anisa Febriani Ariani, Fitri Aty Widyawaruyanti Aulia, Dia Ul Avida In Amy Baiq Ihda Nanda Safriyana Baiq Ridho Amalia Bayani, Faizul Cahyani, Dina Fathia Candra Eka Puspitasari Corry, Maylisa Natalia Dedianto Hidajat Dewi Suryani Dia Ul Aulia Djoko Agus Purwanto Dyke Gita Wirasisya Dyke Gita Wirasisya Dyke Gita Wirasisya Edhi, Narendrani Sasmitaning Einstenia Kemalahayati Hafizah, Gina Tasya Rizka Hajrin, Wahida Handa Muliasari Handa Muliasari Hasan, Muhammad Amir Hidayati, Regina Tria Hilkatul Ilmi Ilmi, Hilkatul Iman Surya Pratama Iman Surya Pratama Pratama Indah Permata Sari Indra Purnomo Indriani, Zulfia Ika Julia Harpina Kadar Riansyah Khairatun, Laziza Iklima Kurniasih Sukenti Lahardo, Devanus Lidya Tumewu Lina Permatasari Mahacita Andanalusia Mahacita Andanalusia Marsih Wijayanti Muhamad Haikhal Muhammad Robby Rizky Mukhlishah, Neneng Rachmalia Izzatul Muliasari, Handa Muthia Cenderadewi, Muthia Neneng Rachmalia Izzatul Mukhlishah Nisa Isneni Hanifa NURUL HIDAYAH Permatasari, Lina Permatasari, Ni Made Ayu Dinda Pratama, Iman Surya Pratiwi, Eskarani Tri Prianggawe, Prianggawe Pujiarohman, Pujiarohman Purwitasari, Neny Putri Nuryana Raissa, Talitha Hasna Ramadhan, Muhammad Rafi Bintang Retno Widyowati Riadi, Putri Oktaviati Riesta Primaharinastiti, Riesta Risnata, Richa Poetri rizki, alpa alfi Rizkika, Adila Safriyana, Baiq Ihda Nanda Siti Rahmatul Aini Suciati Suciati Suciati Suciati Sukardiman sulistanti, Erly Sunarwidhi, Anggit Listyacahyani suryani, Bunga Tri Widiandani Wahida Hajrin Wardani, Ray Haerul Wicaksana, Firman Windah Anugrah Subaidah Wirasisya, Dyke Gita Yayuk Andayani Yunita Yunita Zahra, Nisrina