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All Journal MEDISAINS Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Al-sihah: The Public Health Science Journal Jurnal Ilmiah Ecosystem Narra J Jurnal Ilmiah Kesehatan (JIKA) The Journal of Society Medicine (JSOCMED) Neurona Preventif : Jurnal Kesehatan Masyarakat
Hamid, Firdaus
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Vaginal Microbial Patterns and Matrix Metalloproteinase-9 Levels in relation to Premature Rupture of Membranes Muliati, Tuty; Chalid, Maisuri Tadjuddin; Leonardy, Rudy Butje; Hamid, Firdaus; Wewengkang, Ellen; Asni, Sitti Nur
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 3 July 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i3.2741

Abstract

Introduction: The premature rupture of membranes (PROM) before the onset of labor, characterized by the painless leakage of fluid from the vagina, can lead to fetal distress and increase the risk of cesarean section. This study analyzed the microbial patterns and matrix metalloproteinase 9 (MMP-9) levels in cases of PROM. Methods: This was an observational study with cross-sectional design. Samples were collected from 60 pregnant women diagnosed with PROM who underwent examination and treatment at St. Khadijah I Hospital in Makassar in November 2023. Statistical analysis was performed using the Independent Samples T-Test for microbial patterns and MMP-9 levels. Results: The MMP-9 level in PROM group was significantly higher (1706,78 ± 386,36) compared to non-PROM group (1328,20 ± 1556,22) with p = 0.006. For microbial pattern, E. coli was the predominant bacteria in PROM group (72,0%) compared to non-PROM group (28,0%) with p = 0.004. Conclusion: The results of this study indicate that high MMP-9 level and predominant E. coli presence in the vaginal swab may increase the risk of PROM.
Sleep Quality and Attentional Function in Adolescent Gamers Aged 13-14 Years in Makassar Limbeng, Deni Hansen; Wuysang, Audry Devisanty; Gunawan, David; Hamid, Firdaus; Basir, Hasmawaty; Amran, Muhammad Yunus
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 1 (2024): Volume 6 Nomor 1 April 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i1.575

Abstract

The prevalence of adolescents who spend >5 hours per day playing games has a higher risk of developing sleep disorders. Gaming addiction can cause sleep deprivation and the inability to concentrate, which can lead to attention disorders and impulsive behavior. This study is an analytical observational study with a cross-sectional design that aims to determine the relationship of sleep quality in adolescent gamers to impaired attentional function at SMP Negeri 30 Makassar which was conducted in January 2023. The total subject in the study was 64 people. Most of the subject had a duration of playing games of 3-6 hours per day, which totaled 35 (54,6%) people. Gamers who have abnormal sleep quality are 43 (67,2%). We found that the longer duration of gaming caused the sleep quality to decrease (p-value=0,032). There was a significant relationship between the Pittsburgh Sleep Quality Index (PSQI) score with the visual attention test score (p-value=0,001) and the digit span word test score (p-value=0,006). This study concludes that poor sleep quality is associated with impaired attentional function in the accuracy and reaction domain and impaired attentional function in the working memory domain.
Kadar 8-Oxo-7, 8-Dihydro-2’-Deoxyguanosine (8-Oxo-Dgsn) Dalam Urine Sebagai Biomarker Penuaan Pada Pasien Tb Paru Wijaya, Cathrine Meryani; Santoso, Arif; Hamid, Firdaus; As’ad, Suryani; Bukhari, Agussalim; Zainuddin, Alfian
Preventif : Jurnal Kesehatan Masyarakat Vol. 12 No. 2 (2021): Volume 12 No.2 (2021)
Publisher : Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/preventif.v12i2.448

Abstract

Proses penuaan merupakan proses fisiologis yang tidak dapat dihindari. Pengukuran 8-oxo-dGsn dalam urin berpotensi sebagai cara baru untuk mengevaluasi proses penuaan dalam menentukan dan memperkirakan usia fisiologis. Penelitian ini betujuan untuk mengetahui kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan pada pasien tuberculosis paru. Penelitian ini menggunakan pendekatan case control yakni penderita TB paru sebagai kelompok kasus dan kelompok orang sehat sebagai control dengan jumlah sampel sebanyak 50 orang (25 orang kasus dan 25 orang kontrol). Data dianalisis dengan menggunakan SPSS 21.0 (SPSS, Inc. Chicago, IL) dengan tingkat kemaknaan α=0.05.Hasil penelitian menunjukkan bahwa Kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan pada kelompok kasus rata-rata 3.21±0.88. Kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan pada kelompok kontrol rata-rata 2.38±0.71. Ada korelasi positif antara umur dengan kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan (p < 0,001), dimana semakin bertambah umur maka kadar 8-Hydroxy-deoxyguanosine (8-OHdG) semakin tinggi. Terdapat perbedaan yang bermakna (p:0.001) secara statistik kadar 8-Hydroxy-deoxyguanosine (8-OHdG) sebagai biomarker penuaan antara kelompok kasus dengan kelompok kontrol. Kesimpulan penelitian ini adalah Tuberculosis paru mempercepat proses penuaan yang ditandai dengan peningkatan kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urine sebagai biomarker penuaan.
Co-Authors Abdul Qadar Punagi Amran, Muhammad Yunus Andi Kurnia Bintang, Andi Kurnia Arif Santoso Asni, Sitti Nur ASTUTIATI NURHASANAH As’ad, Suryani Basir, Hasmawaty Billi Bukhari, Agussalim Chaera, Ummi Chalid, Maisuri Tadjuddin David Gunawan Umbas David Gunawan, David Efendi Lukas Eka Savitri Farid, Monika Fitria Fauzia Tamara Rauf Goysal, Yudy Habib Djarkoni, Ilham Handayani, Irda Haruna, Nadyah Hasbullah, Ayu Ameliyah Hatta, Mohammad Hidayah, Najdah Ilhamjaya Patellongi Iqbal Basri, Muhammad Iskandar, Israini W. Jamaluddin, Balqis D. Karimah, Nihayatul Kurnia Bintang, Andi Leonardy, Rudy Butje Lestari, Esa Limbeng, Deni Hansen Lotisna, Mimi Madjid, Baedah Madya, Fatmawati Massi, Muhammad N. Meryana*, A. Kurnia Bintang**, Muh. Akbar**, Susi Aulina**, Yudy Goysal**, Arifin Limoa*** Mochammad Hatta Muliati, Tuty Permana, Andi D. Rahardjo, Sutji P Ratnaningsih, Andi Sri RR. Ella Evrita Hestiandari Safri Safri Setiawan, Denise Dewanto Sultan, Andi Rofian Sunarno, Isharyah Susiawaty Susiawaty, Susiawaty Tamasse, Jumraini Trika Irianta Wewengkang, Ellen Wijaya, Cathrine Meryani Wuysang, Audry Devisanty Yusriyyah, Andi A. Zaenab, St Zainuddin, Alfian