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All Journal MEDISAINS Public Health of Indonesia Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Al-sihah: The Public Health Science Journal Jurnal Ilmiah Ecosystem Narra J Jurnal Ilmiah Kesehatan (JIKA) Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Buletin Kesehatan MAHASISWA The Journal of Society Medicine (JSOCMED) Neurona Preventif : Jurnal Kesehatan Masyarakat
Hamid, Firdaus
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Vaginal Microbial Patterns and Matrix Metalloproteinase-9 Levels in relation to Premature Rupture of Membranes Muliati, Tuty; Chalid, Maisuri Tadjuddin; Leonardy, Rudy Butje; Hamid, Firdaus; Wewengkang, Ellen; Asni, Sitti Nur
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 3 July 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i3.2741

Abstract

Introduction: The premature rupture of membranes (PROM) before the onset of labor, characterized by the painless leakage of fluid from the vagina, can lead to fetal distress and increase the risk of cesarean section. This study analyzed the microbial patterns and matrix metalloproteinase 9 (MMP-9) levels in cases of PROM. Methods: This was an observational study with cross-sectional design. Samples were collected from 60 pregnant women diagnosed with PROM who underwent examination and treatment at St. Khadijah I Hospital in Makassar in November 2023. Statistical analysis was performed using the Independent Samples T-Test for microbial patterns and MMP-9 levels. Results: The MMP-9 level in PROM group was significantly higher (1706,78 ± 386,36) compared to non-PROM group (1328,20 ± 1556,22) with p = 0.006. For microbial pattern, E. coli was the predominant bacteria in PROM group (72,0%) compared to non-PROM group (28,0%) with p = 0.004. Conclusion: The results of this study indicate that high MMP-9 level and predominant E. coli presence in the vaginal swab may increase the risk of PROM.
Sleep Quality and Attentional Function in Adolescent Gamers Aged 13-14 Years in Makassar Limbeng, Deni Hansen; Wuysang, Audry Devisanty; Gunawan, David; Hamid, Firdaus; Basir, Hasmawaty; Amran, Muhammad Yunus
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 1 (2024): Volume 6 Nomor 1 April 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i1.575

Abstract

The prevalence of adolescents who spend >5 hours per day playing games has a higher risk of developing sleep disorders. Gaming addiction can cause sleep deprivation and the inability to concentrate, which can lead to attention disorders and impulsive behavior. This study is an analytical observational study with a cross-sectional design that aims to determine the relationship of sleep quality in adolescent gamers to impaired attentional function at SMP Negeri 30 Makassar which was conducted in January 2023. The total subject in the study was 64 people. Most of the subject had a duration of playing games of 3-6 hours per day, which totaled 35 (54,6%) people. Gamers who have abnormal sleep quality are 43 (67,2%). We found that the longer duration of gaming caused the sleep quality to decrease (p-value=0,032). There was a significant relationship between the Pittsburgh Sleep Quality Index (PSQI) score with the visual attention test score (p-value=0,001) and the digit span word test score (p-value=0,006). This study concludes that poor sleep quality is associated with impaired attentional function in the accuracy and reaction domain and impaired attentional function in the working memory domain.
Kadar 8-Oxo-7, 8-Dihydro-2’-Deoxyguanosine (8-Oxo-Dgsn) Dalam Urine Sebagai Biomarker Penuaan Pada Pasien Tb Paru Wijaya, Cathrine Meryani; Santoso, Arif; Hamid, Firdaus; As’ad, Suryani; Bukhari, Agussalim; Zainuddin, Alfian
Preventif : Jurnal Kesehatan Masyarakat Vol. 12 No. 2 (2021): Volume 12 No.2 (2021)
Publisher : Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/preventif.v12i2.448

Abstract

Proses penuaan merupakan proses fisiologis yang tidak dapat dihindari. Pengukuran 8-oxo-dGsn dalam urin berpotensi sebagai cara baru untuk mengevaluasi proses penuaan dalam menentukan dan memperkirakan usia fisiologis. Penelitian ini betujuan untuk mengetahui kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan pada pasien tuberculosis paru. Penelitian ini menggunakan pendekatan case control yakni penderita TB paru sebagai kelompok kasus dan kelompok orang sehat sebagai control dengan jumlah sampel sebanyak 50 orang (25 orang kasus dan 25 orang kontrol). Data dianalisis dengan menggunakan SPSS 21.0 (SPSS, Inc. Chicago, IL) dengan tingkat kemaknaan α=0.05.Hasil penelitian menunjukkan bahwa Kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan pada kelompok kasus rata-rata 3.21±0.88. Kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan pada kelompok kontrol rata-rata 2.38±0.71. Ada korelasi positif antara umur dengan kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan (p < 0,001), dimana semakin bertambah umur maka kadar 8-Hydroxy-deoxyguanosine (8-OHdG) semakin tinggi. Terdapat perbedaan yang bermakna (p:0.001) secara statistik kadar 8-Hydroxy-deoxyguanosine (8-OHdG) sebagai biomarker penuaan antara kelompok kasus dengan kelompok kontrol. Kesimpulan penelitian ini adalah Tuberculosis paru mempercepat proses penuaan yang ditandai dengan peningkatan kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urine sebagai biomarker penuaan.
Efek Larvasida Daun Jarak Kepyar (Ricinus communis linn) pada Organisme non-target : Larvicidal Effect of Castor Leaves (Ricinus communis linn) on non-Target Organisms Dwicahya, Bambang; Arsin, A. Arsunan; Ishak, Hasanuddin; Hamid, Firdaus
Buletin Kesehatan Mahasiswa Vol. 4 No. 2 (2026): Buletin Kesehatan MAHASISWA
Publisher : Fakultas Kesehatan Masyarakat Universitas Tompotika Luwuk Banggai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51888/jpmeo.v4i2.405

Abstract

Penyakit Demam Berdarah Dengue (DBD) masih menjadi masalah kesehatan yang signifikan, termasuk Indonesia. Tanaman jarak kepyar telah diketahui memiliki sifat larvasida terhadap larva nyamuk aedes pada beberapa penelitian, namun perlu dilakukan studi tentang pengaruh efek residu larvasida daun jarak kepyar untuk mengevaluasi risiko potensial dan efek jangka Panjang dan peninjauan ekstrak daun jarak kepyar terhadap organisme non-target. Metode penelitian  larvasida ekstrak daun jarak kepyar dilakukan menggunakan metode maserasi. Pembuatan ekstrak daun jarak kepyar menggunakan 4 jenis pelarut yang berbeda. Bahan Daun Jarak Kepyar dibagi menjadi dua yaitu daun muda dan daun tua. efek pada organisme non-target dilakukan pengamatan sampai pada hari ke-7 setelah perlakuan. Hasil penelitian menunjukkan efek ekstrak daun jarak (menggunakan 4 pelarut) baik daun muda maupun daun tua terhadap organisme non-target (ikan guppy) tidak menimbulkan mortalitas pada ikan selama 3 kali percobaan. Kesimpulan dalam penelitian ini yaitu ekstrak daun jarak kepyar tidak menimbulkan efek mortalitas pada ikan guppy. Dengue Hemorrhagic Fever (DHF) is still a significant health problem, including in Indonesia. The castor plant has been known to have larvicidal properties against aedes mosquito larvae in several studies, but a study is needed on the effect of residual effects of castor leaf larvicidal to evaluate potential risks and long-term effects and review of castor leaf extract on non-target organisms. Research method: castor leaf extract larvicidal was carried out using the maceration method. The manufacture of castor leaf extract used 4 different types of solvents. Castor leaf material was divided into two, namely young leaves and old leaves. the effect on non-target organisms was observed until the 7th day after treatment. The results showed that the effect of castor leaf extract (using 4 solvents) both young leaves and old leaves on non-target organisms (guppy fish) did not cause mortality in fish during 3 trials. The conclusion in this study is that castor leaf extract does not cause mortality in guppy fish.
Non-adherence to medication, malaria relapse, and asymptomatic reservoirs in malaria transmission: A narrative review Sahiddin, Muhamad; Ishak, Hasanuddin; Arsin, Andi Arsunan; Mallongi, Anwar; Arsyad, Muhammad; Hamid, Firdaus
Public Health of Indonesia Vol. 11 No. 4 (2025): October - December
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v11i4.1032

Abstract

Background: Malaria elimination remains a pressing global health priority, yet progress is hindered by interconnected human-driven factors that sustain residual transmission. Objectives: This review aims to integrate and analyze key factors driving residual malaria transmission, particularly non-adherence to anti-malarial medication, relapse of Plasmodium vivax and P. falciparum infections, and the persistence of asymptomatic parasite reservoirs. Methods: A narrative review was conducted by synthesizing findings from peer-reviewed studies, including observational studies, clinical trials, and program evaluations. Relevant articles were identified through PubMed, Scopus, Google Scholar, and Web of Science databases. Results: Demographic, behavioral, and health system factors were consistently associated with incomplete treatment, which in turn doubled relapse risk and extended the duration of gametocyte carriage. Biological factors, such as dormant hypnozoites and CYP2D6 polymorphisms that reduce primaquine metabolism, increased the likelihood of recurrent infections. Additionally, asymptomatic carriers disproportionately younger and mobile populations sustained transmission beyond the reach of routine surveillance. Unlike previous reviews that examined these factors separately, this review integrates them into a unified framework, emphasizing their synergistic effects on residual transmission and identifying leverage points for targeted interventions. Conclusion: Addressing residual malaria transmission requires coordinated strategies, including community-supervised or directly observed radical cure regimens, genotype-informed dosing strategies, molecular surveillance for asymptomatic infections, and culturally tailored adherence support. These interventions are essential to strengthen malaria elimination programs and advance progress toward national and global goals by 2030. Keywords: adherence medication; relapse; transmission; endemic; malaria
Prevalence and Determinants of Fluor Albus Among Postmenopausal Women Without Symptoms: Implications for Public Health Screening Programs Purnamasari, Yenti; Hamid, Firdaus; Saimin, Juminten; Bukhari, Agussalim
Public Health of Indonesia Vol. 11 No. 4 (2025): October - December
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v11i4.1146

Abstract

Background: Postmenopausal women are susceptible to vaginal infections due to hormonal changes that alter the vaginal microbiota, potentially leading to fluor albus even in the absence of symptoms. Objective: This study aims to determine the prevalence of Fluor Albus and assess its relationship with age, age of menopause, and duration of menopause in postmenopausal women. Methods: A cross-sectional study was conducted from April to July 2024 at Kendari City, Southeast Sulawesi, Indonesia. A total of 35 postmenopausal women were selected through total sampling, excluding those with chronic illnesses, vaginal symptoms, recent antibiotic use, or vaginal cleansing. Data were collected through participant-completed forms and laboratory examinations using KOH smear and Gram staining to detect the presence of Candida and pathogen bacteria. Data were analyzed using descriptive statistics and Chi-square tests. Results: The prevalence of fluor albus in postmenopausal women in this study was 68.6%. There was no statistically significant relationship between age (0.628), age of menopause (0.150), or duration of menopause (0.269) with the incidence of fluor albus. Conclusion: The prevalence of fluor albus among postmenopausal women in this study was high and was not related with age, menopausal age and duration of menopause, underlining the importance of regular reproductive health screening in the postmenopausal group.
Health Literacy Based Health Promotion Strategy for the Prevention of Periodontal Disease Caused by Porphyromonas gingivalis in Communities Exposed to Environmental Heavy Metals: A Scoping Review Jelita, Helena; Achmad, Harun; Ariifn, Syamsul; Jayanti, Ira; Hanasia, Hanasia; Hamid, Firdaus
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 9 No. 2 (2026): February 2026
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v9i2.9310

Abstract

Introduction: Periodontal disease in communities exposed to environmental heavy metals represents not only a biological problem but also a public health challenge closely linked to limitations in health literacy. While the pathogenic role of Porphyromonas gingivalis and the toxic effects of heavy metals such as Pb, Cd, and Hg contribute to inflammation and periodontal tissue damage, insufficient health literacy constrains individuals’ capacity to recognize risks, adopt preventive behaviors, and engage in effective disease prevention strategies. Methods: A scoping review was conducted using the PEOS framework, with article searches in PubMed, ScienceDirect, EBSCO, and Google Scholar. Of the 512 articles identified, 20 met the inclusion criteria (2015–2023) and were analyzed through data charting and quality assessment. Results: Heavy metals have been shown to increase the risk of periodontitis through immune suppression, oxidative stress, and changes in the oral microbiota. P. gingivalis enhances pathogenesis by disrupting epithelial defenses and triggering chronic inflammation. Increasing health literacy has been shown to be influential in encouraging preventative behaviors and managing environmental exposure risks. Conclusion: Strengthening health literacy is a central and unifying strategy in reducing periodontal disease risk in populations exposed to environmental heavy metals. Integrating biologically informed risk communication with community-based, literacy-sensitive health promotion interventions enhances prevention efforts against periodontal disease associated with P. gingivalis in high-risk communities
Larvicidal Activity of Young and Old Leaves of Ricinus communis linn (Castor) with Ethanol, Aquades, Ethyl Acetate, and N-hexane solvents against Aedes sp. Dwicahya, Bambang; Arsin, A. Arsunan; Ishak, Hasanuddin; Hamid, Firdaus; Kanan, Maria; Mallongi, Anwar; Maria, Ida Leida; Birawida, Agus Bintara; Syahrir, Muhammad
Public Health of Indonesia Vol. 12 No. 1 (2026): January - March
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v12i1.1412

Abstract

Background: Dengue fever remains a major public health problem in tropical regions, including Indonesia, where vector control relies heavily on synthetic larvicides that pose environmental and health concerns. Plant-based larvicides have emerged as promising alternatives; however, comparative evidence regarding the influence of solvent polarity and leaf developmental stage on larvicidal efficacy remains limited. Objectives: This study evaluated the larvicidal activity of young and old castor bean leaf extracts obtained using different solvents against Aedes sp. larvae. Method: A laboratory-based experimental study was conducted following WHO guidelines for mosquito larvicide testing. Young and old leaves of castor were extracted separately using n-hexane, ethyl acetate, ethanol, and distilled water through multistage maceration. Third-instar Aedes sp. larvae were exposed to graded concentrations (75–200 ppm) of each extract, with 25 larvae per treatment and three replications. Larval mortality was recorded hourly for 24 hours. Probit analysis was used to determine LC₅₀ and LC₉₀ values with 95% confidence intervals, and differences among treatments were analyzed using one-way ANOVA (p < 0.05). Results: All extracts exhibited larvicidal activity against Aedes sp., with efficacy varying according to solvent type and leaf age. Ethanol extracts of old leaves produced the highest larval mortality, while ethyl acetate extracts of young leaves showed the lowest LC₅₀ values. Phytochemical screening confirmed the presence of alkaloids, flavonoids, saponins, tannins, and steroids in most extracts. LC₅₀ values ranged from 131.403 to 410.225 ppm, whereas LC₉₀ estimates were substantially higher and exceeded the tested concentration range, indicating extrapolation beyond observed data.  Conclusion: The larvicidal effectiveness of castor leaf extracts against Aedes sp. is influenced by both solvent polarity and leaf developmental stage. Old leaves extracted with ethanol and young leaves extracted with ethyl acetate demonstrated comparatively higher larvicidal potential. These findings support the potential of castor as a botanical larvicide, although further studies incorporating standard larvicide controls, quantitative phytochemical analysis, and field validation are required before operational application.   Keywords: Aedes sp; ricinus communis linn; castor
Co-Authors A. Arsunan Arsin Abdul Qadar Punagi Agus Bintara Birawida Amran, Muhammad Yunus Andi Arsunan Arsin Andi Kurnia Bintang, Andi Kurnia Anwar Mallongi Arif Santoso Ariifn, Syamsul Asni, Sitti Nur ASTUTIATI NURHASANAH As’ad, Suryani Basir, Hasmawaty Billi Bukhari, Agussalim Chaera, Ummi Chalid, Maisuri Tadjuddin David Gunawan Umbas David Gunawan, David Dwicahya, Bambang Efendi Lukas Eka Savitri Farid, Monika Fitria Fauzia Tamara Rauf Goysal, Yudy Habib Djarkoni, Ilham Hanasia, Hanasia Handayani, Irda Harun Achmad, Harun Haruna, Nadyah Hasanuddin Ishak Hasbullah, Ayu Ameliyah Hatta, Mohammad Hidayah, Najdah Ida Leida Maria Ilhamjaya Patellongi Iqbal Basri, Muhammad Iskandar, Israini W. Jamaluddin, Balqis D. Jayanti, Ira Jelita, Helena Juminten Saimin, Juminten Karimah, Nihayatul Kurnia Bintang, Andi Leonardy, Rudy Butje Lestari, Esa Limbeng, Deni Hansen Lotisna, Mimi Madjid, Baedah Madya, Fatmawati Maria Kanan Massi, Muhammad N. Meryana*, A. Kurnia Bintang**, Muh. Akbar**, Susi Aulina**, Yudy Goysal**, Arifin Limoa*** Mochammad Hatta Muhammad Arsyad Muliati, Tuty Permana, Andi D. Purnamasari, Yenti Rahardjo, Sutji P Ratnaningsih, Andi Sri RR. Ella Evrita Hestiandari Safri Safri Sahiddin, Muhamad Setiawan, Denise Dewanto Sultan, Andi Rofian Sunarno, Isharyah Susiawaty Susiawaty, Susiawaty Tamasse, Jumraini Trika Irianta Wewengkang, Ellen Wijaya, Cathrine Meryani Wuysang, Audry Devisanty Yusriyyah, Andi A. Zaenab, St Zainuddin, Alfian