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All Journal Journal of Degraded and Mining Lands Management Jurnal Informatika dan Teknik Elektro Terapan English and Literature Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Al-Kimia Jurnal Teknologi Pertanian (Agricultural Technology Journal) Gema Kampus IISIP YAPIS Biak Journal of Stem Cell Research and Tissue Engineering Indonesian TESOL Journal CIVICS: Jurnal Pendidikan Pancasila dan Kewarganegaraan Jurnal Agrisistem International Journal of Educational Review, Law And Social Sciences (IJERLAS) Multidiciplinary Output Research for Actual and International Issue (Morfai Journal) Journal of Educational Management and Instruction (JEMIn) International Journal of Social Science, Educational, Economics, Agriculture Research, and Technology (IJSET) AJAD : Jurnal Pengabdian kepada Masyarakat ISTIQRA: JURNAL HASIL PENELITIAN LingPoet: Journal of Linguistics and Literary Research International Conference on Health Science, Green Economics, Educational Review and Technology (IHERT) Jurnal Teknik Transportasi LAWPASS Science and Technology: Jurnal Pengabdian Masyarakat Journal of Soil Quality and Management International Journal of Law and Society Sains: Jurnal Kimia & Pendidikan Kimia Journal of International Islamic Law, Human Right and Public Policy Jurnal Dinamika Sosial dan Sains Edukasi dan Didatika: Jurnal Ilmiah Pendidikan Dasar Ekopedia: Jurnal Ilmiah Ekonomi Jurnal Pengembangan Sains dan Teknologi WORKFORCE: Jurnal Ilmiah Manajemen dan Bisnis Scientific: Journal of Computer Science and Informatics
Dahlan
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Journal : Journal of Stem Cell Research and Tissue Engineering

 1 
UTILIZATION OF STEM CELL RESEARCH IN MICROGRAVITY FOR INNOVATION IN CELLULAR THERAPY ON EARTH Hendrizal; Dahlan; Gower
Journal of Stem Cell Research and Tissue Engineering Vol. 8 No. 2 (2024): JOURNAL OF STEM CELL RESEARCH AND TISSUE ENGINEERING
Publisher : Stem Cell Research and Development Center, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jscrte.v8i2.67764

Abstract

Recent advancements in stem cell biology, coupled with developments in space exploration, have opened new avenues for regenerative medicine. Microgravity environments in space induce significant physiological changes in the human body, such as muscle atrophy, decreased bone density, and immune system impairments, mimicking accelerated aging and chronic disease progression. These conditions offer a unique opportunity to study stem cell behavior, proliferation, and differentiation, which occur at a faster pace in space compared to Earth. The three-dimensional (3D) microgravity environment provides a more accurate representation of the human body’s natural state than traditional two-dimensional culture systems, fostering enhanced stem cell development. Among the various stem cells studied in space, mesenchymal stem cells (MSCs) have shown promise for therapeutic applications, including the treatment of stroke, cancer, and neurodegenerative diseases. Research aboard the International Space Station (ISS) has demonstrated that MSCs maintain their properties, proliferate, and differentiate under microgravity conditions, offering potential for future therapies. Additionally, MSCs exhibit resistance to space radiation, protecting astronauts from its harmful effects by promoting tissue repair and releasing regenerative factors. This radiation resistance, coupled with cryopreservation techniques, enables MSCs to be used in long-duration space missions. The ongoing research on MSCs in space not only supports astronaut health but also holds the potential to revolutionize regenerative medicine on Earth. By understanding how microgravity influences stem cell behavior, scientists are uncovering critical insights into tissue repair and cell function, paving the way for innovative treatments for aging-related diseases and other medical conditions. These findings highlight the broader implications of space-based stem cell research for advancing human health both in space and on Earth.
Co-Authors Abdul Kadir Ahmad Abdullah, Nursiah Adrianah Ahmad Muzammil Akmal Umar Alfiana Anas Laode andi mirza Asia Habby, Fihanas Permada AZHAR ANSI, AZHAR Azis H, Abd Aziz Sakti Nugroho aziza, A.wafiq Bachtiar Simatupang Bambang Fitrianto CHANDRA DEWI Djamil Hasim Eliana Fadhil Rifgi Pratama fahrudin Fajar Fitriani , Andi Alya Fransiscus S. Rembon Gaffar, Syamsul Bakhri Gower Hasriyodan Hendrizal Henry Aspan Herdian, Freddy idawia Intan Chairun Nisa Iwan Sahat Maruli Simanjuntak Jalal , Novita Maulidya kahar, kaharuddin Khaeruddin La Harimu La Ode Ahmad Nur Ramadhan Laksana, Mohammad Alfi Nanda Laode Muhammad Harjoni Kilowasid Laode Sabaruddin Listiana Sri Mulatsih M. Anas M. Jafar Masykur Rauf, Masykur Maulana Muhammad Jogo Samudro MAYANG SARI Muh. Edihar Muhammad Amirul Mu'min Muhammad Andi Muhammad Farhan Pratama MUHAMMAD RIZAL Mulyati Mulyati Mutmainnah Nasrum Nurhaedah Parapa, Imelia Rachman, Muhammad Aimar Ramlan Randy Asmoro Dwi Purnomo Regina D. Krobo Rivai, Iskandar Riza Firdaus Robert Molenaar Ruland A. Rantung Rustam Musta Saida Rasnovi Sri Handayani Sri Sartini Muniaha Sukartono Sukmana, Uza Sumardi, Lalu surianto, suarni Susmihara Susmihara Syahruni Junaid, Syahruni Syaiful Dinata Syam, Rahmawati Tamara, Adrian Kristanto TAYIB, ADE SOPYAN HADI Teuku Muttaqin Mansur TRESJIA CORINA RAKIAN, TRESJIA CORINA Unsha, Fuji Attariq Veni Sofia Wa Ode Mulyana Wibisono, Gendoet Indarto Wijaya, Muh Irfan Wildam, Andi Arwinda Yana Safitri, Yana Yopa Emalia Fajarini Yuliansyah, Riski Yusra Yusuf, Putri Zulfikar Zumhur Alamin