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All Journal Jambura Journal of Health Sciences and Research Jurnal Prima Medika Sains Journal of Multidisciplinary Applied Natural Science JIFI (Jurnal Ilmiah Farmasi Imelda) Jurnal Locus Penelitian dan Pengabdian Buletin Kedokteran dan Kesehatan Prima Jurnal Multidisiplin Sahombu Ranah Research : Journal of Multidisciplinary Research and Development Herbal Medicine Journal Journal of Pharmaceutical and Sciences. Jurnal Sains Farmasi dan Kesehatan Jurnal Indah Sains dan Klinis Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Razoki, Razoki
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UJI AKTIVITAS ANTIOKSIDAN METODE DPPH DARI EKSTRAK ETANOL DAUN SUKUN (Artocarpus altilis L.) MENGGUNAKAN METODE MASERASI Sari, Cindy Kurnia; Razoki, Razoki; Novriani, Erida
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 9 No. 2 (2026): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v9i2.2193

Abstract

Breadfruit leaves (Artocarpus altilis L.) area plant with various health benefits due to their natural chemical compounds, one of which acts as an antioxidant. Antioxidants are compounds that can halt the oxidation process by donating electrons, there by protecting normal cells, fats, and proteins from damage caused by free radicals. The concentration of an antioxidant that causes a 50% reduction in DPPH activity is referred to as the IC50.  The objective of this study was to determine the effectiveness of ethanol extract from breadfruit leaves in combating oxidation using the DPPH method. The results showed an IC50 value of 6.66 ppm for the extract, indicating very strong antioxidant activity, although it was more effective compared to vitamin C, which served as a positive control with an IC50 value of 1.15 ppm. This difference in effectiveness is influenced by the amount of phenolic compounds present and the potential pro-oxidant effects at higher concentrations. In summary, breadfruit leaves have high potential as asource of natural antioxidants and can be used to develop pharmaceutical products to treat degenerative diseases.
Co-Authors Adek Amansyah Ana Fiske Hotmaida Simanjuntak Arbita Huri Astriani Natalia Br Ginting Bangar, Roy Indrianto Bengimiate, Nuriza Binarwan Halim br. Sembiring, Novitaria br. Silalahi, Aancel Budi, Andre Chiuman, Linda Edlin, Edlin Elvi Sasmi Erida Novriani Finna Piska Fioni Fioni Fioni, Fioni Friska Rezki Hasibuan Ginting, Astriani Natalia Br Ginting, Chrismis Novalinda Hanjaya, Hanjaya Harahap, Halimah Hariyadi Dharmawan Syahputra Hartopo, Haqi Hotvera Merianis, Hotvera Hutauruk, Rico Halim Iksen, Iksen Lister, INE Lubis, Zahra Khairunnisa Manao, Merlianasari Manullang, Lampita Bellina Masriani . Merianis, Hotvera Meutia, Rena Mutia, Maya Sari Nardi, Leo Nasution, Chairul Radjab Nazla Deswita Siregar Nerly Juli Pranita Simanjuntak Neswita, Elfia Novita, Cut Elvira Novitaria Br Sembiring Novriani, Erida Ongko, Nicolas Xavier Refi Ikhtiari Reh Malem br Karo Roy Indrianto Bangar Siagian Salsabila, Dinda Ayu Samin, Buter Sari, Cindy Kurnia Septia, Evianti Dwi Simanjuntak, Nerly Juli Pranita Sinaga, Ade Putra Fratama Sitorus, Christina Berliana Soekardi, Adi Syahputra, Hariyadi Dharmawan Tanjung, Fahrul Azmi Tarigan, Antje Irmella Tarigan, Susiani Tesa, Catrin Angelica Putri Vera Estefania Kaban Wijaya, Johanna Fransiska Wilson Kanggaran Yohanes Dewantoro Situmorang