Article Per Year (5 Year)
p-Index From 2021 - 2026
3.947
P-Index
This Author published in this journals
All Journal Jurnal Ilmu Pertanian Indonesia ACTA VETERINARIA INDONESIANA Jurnal Sain Veteriner Buletin Peternakan Jurnal Veteriner Jurnal MIPA JITRO (Jurnal Ilmiah dan Teknologi Peternakan Tropis) PROSIDING SEMINAR KIMIA Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) Bioma : Jurnal Biologi Indonesia ARSHI Veterinary Letters Jambura Physics Journal JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Fisika dan Terapannya Jurnal Abdimas ADPI Sains dan Teknologi Jurnal Pusat Inovasi Masyarakat Jurnal Kedokteran Hewan Jurnal Veteriner Nusantara Current Biomedicine
koekoeh santoso
IPB University
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Education Electrical & Electronics Engineering Energy Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Veterinary Other

Published : 44 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Jurnal MIPA

 1 
Nilai Indeks Aterogenik Plasma (IAP) Dan Indeks Castelli (IC) Mencit Model yang Diinduksi Minyak Trans Supiyani, Atin; Sukmawati, Dalia; Kusumorini, Nastiti; Santoso, Koekoeh; Satyaningtijas, Aryani Sismin
Jurnal MIPA Vol 10, No 2 (2021)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jmuo.10.2.2021.34094

Abstract

dikembangkan melalui pendekatan hewan model untuk mempelajari tentang PJK. Minyak goreng yang digunakan secara berulang dapat meningkatkan kadar asam lemak bebas yang berdampak negatif bagi kesehatan terutama jantung dan pembuluh. Tujuan dari penelitian ini mengukur indeks aterogenik plasma (IAP) dan indeks Castelli (IC) dari mencit model yang diinduksi minyak trans (MT). Sebanyak 16 ekor mencit galur DDY dibagi menjadi 4 kelompok yaitu mencit yang diinduksi 20% minyak trans (MT20), 40% minyak trans (MT40) dan 60% minyak trans (MT60) dan kontrol (K). Persentase minyak trans diberikan berdasarkan dari total energi konsumsi pakan harian. Minyak trans diberikan per oral sehari sekali selama 70 hari. Darah diambil pada hari ke-70 dari vena lateral ekor tikus untuk mengukur profil lipid plasma yaitu kolesterol total, trigliserida (TG), High Density Lippoprotein (HDL) dan Low Density Lipoprotein (LDL) plasma  menggunakan alat uji cepat Lipid Pro®. Nilai Indeks Aterogenik Plasma (IAP) yaitu log (TG/HDL) dan Indeks Castelli (IC) yaitu LDL/HDL. Hasil pengkuran profil lipid plasma menunjukkan kolesterol total, trigliserida, HDL dan LDL plasma pada kelompok MT meningkat secara nyata dibandingkan kontrol (sig<0,05). Nilai IA pada mencit yang diberi minyak trans berbeda nyata dari kontrol (sig<0,05) dan memiliki risiko tinggi. Nilai IC pada mencit yang diberi minyak trans berbeda nyata dari kontrol (sig<0,05) dan memiliki risiko sedang-tinggi. Minyak trans meningkatkan nilai indeks aterosklerosis dan indeks resiko koroner mencit.Coronary Heart Disease (CHD) is a "silent killer" disease. Various studies were developed through an animal model approach to studying CHD. Cooking oil that is used repeatedly can increase levels of free fatty acids which have a negative impact on health, especially the heart and vessels. The aim of this study was to measure the plasma atherogenic index (IAP) and Castelli index (IC) of trans oil-induced model mice (MT). A total of 16 DDY mice were divided into 4 groups, namely mice induced with 20% trans oil (MT20), 40% trans oil (MT40) and 60% trans oil (MT60) and control (K). The percentage of trans oil is given based on the total energy consumption of the daily feed. Trans oil is given orally once a day for 70 days. Blood was taken on the 70th day from the lateral vein of the rat tail to measure the plasma lipid profile, namely total cholesterol, triglycerides (TG), High Density Lippoprotein (HDL) and plasma Low Density Lipoprotein (LDL) using the Lipid Pro® rapid test kit. The Plasma Atherogenic Index (IAP) values are log (TG / HDL) and the Castelli Index (IC) is LDL / HDL. The results of measuring the plasma lipid profile showed that plasma total cholesterol, triglycerides, HDL and LDL in the MT group increased significantly compared to the control (sig<0,05). The IA value in mice treated with trans oil was significantly different from the control (sig<0.05) and had a high risk. The IC value in mice treated with trans oil was significantly different from the control (sig<0.05) and had a medium-high risk. Trans oil increased the atherosclerosis index and coronary risk index of mice.
Co-Authors A.S. Satyaningtijas Abdul Zahid Abidah, Puri Adzrok ACHMAD FARAJALLAH Afiff , Usamah Afrilia Bagus Putri Hapsari Agik Suprayogi Agung Eru Wibowo Agus Wijaya Ainul Khadija Saleema Akhiruddin Maddu Aldo Febriano Tarigan Alfarisi, Hamzah Amalia Khairina Amrozi Andayani, Prawita Lintang Anindita Sista Widyadhari Anindita Sista Widyadhari Annisa Madyanti Geminastiti Parampasi Ardilasunu Wicaksono Asah Hilaliah Athirah Rerana Fitrianthy Aziz, Sandra Dalia Sukmawati Damhuri Damhuri Damiana Rita Ekastuti Daryanti, Edhita Putri David Anwar Denny Widaya Lukman Denny Widya Hikman Desrayni Hanadhita Dhani S. Wibawa Dwi Nurhidayah Zubaidah Edi Sukmawinata Edi Sukmawinata Elok Budi Retnani Etih Sudarnika Farida Cintiyah Gandasari, Ira Agustina Dewi Gilang Kala Maulana, Gilang Kala Hadri Latif heny Nitbani HERA MAHESHWARI Herwin Pisestyani Huda Shalahudin Darusman I wayan Teguh Wibawan Ika Mayasari, Ni Luh Putu Ikhwan Wirahadikesuma ikhwan wirahadikesuma Imelda Yanti Lumongga Simanjuntak Irfan Nurhidayat, Irfan Irwan Oktoni Isdoni Bustaman Isnaeni Isnaeni Isnaeni Jefri Naldi Jumadin, La Jumardin jumardin jumardin Kholidah Fauziah Komariah komariah komariah Kudang Boro Seminar Kusnandar Anggadiredja La Jumadin La Jumadin La Jumadin La Jumadin Lili Darlian Lili Darlian M. Ichwan Mutaqqin MADE ASTAWAN Made Darawati Maharani Salsabila Mahendra, Arindina Maneewong, Sattabongkoch Maria, Joanita Maryce Agusthinus Walukou Mawali, Maharja Mokhamad Fakhrul Ulum, Mokhamad MUHAMMAD AGIL Muhammad Primadevan Pascaharchana Noor Nadhear Nadadyanha Dannar NASTITI KUSUMORINI Nenis Rahma Wulandari Niken Ulupi Nugraha, Arifin Budiman Nuri Ardiani Nurul Masyita, Nurul Okta Irviana Muminin Okti Nadia Poetri Ong Huey, Lynette Pudji Achmadi Putri, Anisya Saeila Putri, Fatimatus Sa’diyah Putri, Maritrana Rahmadhani, Elsi Rani Audona Rasyida Ulfa Ratasha Zahwanda Rachmani Ridi Arif Ridzky Pratama Risqika Akla Velayati Rivangga Yuda Hendika Ronald Tarigan Rotinsulu, Dordia Anindita Sadiah, Siti Santoso, Hera Sasmita, Annissa Nuridfi Satvika, Fadhila Saut Renato Rahmat Simanjuntak sri murtini . Supiyani, Atin Tarigan, Ronald Tutik Wresdiyati Ulfatin Khoiriyah Herowati Umi Cahyaningsih Warysatul Ummah Wasmen Manalu Wijaya, Yanuar Restu Yulvian Sani Yusuf Ridwan Zora, Nelda Fliza Zulvia Maika