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All Journal HAYATI Journal of Biosciences JPMS (Jurnal Pendidikan Matematika dan Sains) Jurnal Penelitian Saintek INOTEKS : Jurnal Inovasi Ilmu Pengetahuan, Teknologi, dan Seni Jurnal Pendidikan Matematika dan IPA Jurnal Sains Dasar Jurnal Matematika & Sains Journal of Degraded and Mining Lands Management Jurnal Pendidikan Biologi Indonesia JPS Unimus Jurnal Inovasi Pendidikan IPA Jurnal Edukasi Matematika dan Sains Indonesian Journal of Science and Technology Jurnal Tadris Kimiya Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan Jurnal Ilmiah Peuradeun Jurnal Penelitian Pendidikan IPA (JPPIPA) Indonesian Journal of Chemistry Warta Penelitian Perhubungan Faletehan Health Journal Molekul: Jurnal Ilmiah Kimia JKPK (Jurnal Kimia dan Pendidikan Kimia) Chemistry Education Practice Jurnal Inovasi Pembelajaran Kimia (Journal Of Innovation in Chemistry Education) Borobudur Journal Evaluation in Education (JEE) Jurnal Keperawatan 'Aisyiyah Jurnal Pendidikan Sains Indonesia (Indonesian Journal of Science Education) Molekul: Jurnal Ilmiah Kimia Jurnal Elemen Kimia Jurnal Riset Pembelajaran Kimia IJOBI Holistik Jurnal Kesehatan Jurnal Pendidikan MIPA Indonesian Journal of Science and Education Warta Penelitian Perhubungan IJIS Edu : Indonesian Journal of Integrated Science Education
SRI ATUN
Universitas Negeri Yogyakarta
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Other

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Metode Isolasi dan Identifikasi Struktural Senyawa Organik Bahan Alam Sri Atun
Borobudur Vol. 8 No. 2 (2014): Jurnal Konservasi Cagar Budaya Borobudur
Publisher : Balai Konservasi Borobudur Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33374/jurnalkonservasicagarbudaya.v8i2.132

Abstract

Beberapa penelitian etnomedika yang tercatat dalam dokumen kuno dari beberapa wilayah Indonesia menunjukkan adanya beberapa jenis tumbuhan yang dapat digunakan sebagai obat untuk menyembuhkan berbagai penyakit, maupun dapat diterapkan pada benda yang mengalami permasalahan akibat aktivitas suatu organisme. Senyawa bioaktif dapat berkhasiat sebagai anti bakteri, anti jamur, anti serangga dan lain-lain. Namun demikian, agar tumbuhan tersebut dapat dikembangkan dan dilestarikan perlu dilakukan penelitian yang berkelanjutan, sehingga dapat diketahui jenis senyawa bioaktifnya. Untuk mengetahui kandungan senyawa aktif dari tumbuhan perlu dilakukan isolasi, sehingga diperoleh senyawa murni. Selanjutnya dari senyawa murni yang diperoleh belum memiliki makna apabila belum diketahui struktur molekulnya. Dalam artikel ini akan dibahas mengenai metode isolasi dan penentuan struktur senyawa alam.
Characterization of Curcuminoid from Curcuma xanthorrhiza and Its Activity Test as Antioxidant and Antibacterial Sri Atun; Nurfina Aznam; Retno Arianingrum; Senam Senam; Bian Ihda An Naila; Astuti Lestari; Nur Aini Purnamaningsih
Molekul Vol 15, No 2 (2020)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (569.917 KB) | DOI: 10.20884/1.jm.2020.15.2.540

Abstract

Curcuminoids are the main component found in many Zingiberaceae family plants. The aim of this study was to characterize curcuminoid and its activity test as an antioxidant and antibacterial. Dryed powder of C. xanthorrhiza (1 kg) was macerated with ethanol for 24 hours at room temperature. Ethanol extract of C. xanthorrhiza was subsequently fractionated with n-hexane and chloroform to take the yellow or orange indicated contain of curcuminoids. Analysis of total phenolic levels was carried out by the Follin-Ciaocalteau method. The isolation of curcuminoid componens from this fraction  was carried out by chromatographic method and the structure elucidation was performed by interpretation of spectroscopic data, including UV, IR, 1H and 13C NMR 1D and 2D. The antioxidant activity test used the DPPH (2,2-diphenylpicrylhydrazyl) method, while the antibacterial activity test used Kirby Bauer test diffusion method. The results showed that the curcuminoid fraction yield was 10.06%  from ethanol extract C. xanthorrhiza. The total phenolic content of curcuminoids fraction was 745.45 ± 18.5 mg galic acid (GA)/g extract. Curcuminoids fraction was isolated a known compound desmethoxycurcumin (1). The content of demethoxycurcumin (1) in curcuminoid fraction is 20.97 %.The antioxidant activity of curcuminoids fraction showed strongest activity with IC50 24.98 µg/ml. Antibacterial activity against of the four pathogenic bacteria showed medium activity. The study suggests that curcuminoids extract from C. xanthorrhiza rhizome have potential compounds could be suitable for antioxidant and the treatment of various infections caused of microbial.
PENGEMBANGAN PERANGKAT PEMBELAJARAN KIMIA SMA KELAS XI MATERI ASAM BASA UNTUK PEMBENTUKAN KARAKTER PESERTA DIDIK Nanang Rahman; Sri Atun
JKPK (Jurnal Kimia dan Pendidikan Kimia) Vol 1, No 1 (2016): JKPK (Jurnal Kimia dan Pendidikan Kimia)
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1312.02 KB) | DOI: 10.20961/jkpk.v1i1.10098

Abstract

Tujuan penelitian ini adalah untuk: (1) mengembangkan perangkat pembelajaran kimia SMA kelas XI materi asam basa untuk meningkatkan hasil belajar dan pembentukan karakter peserta didik, (2) mengetahui kualitas dari perangkat pembelajaran yang dikembangkan, dan(3) mengetahui perbedaan hasil belajar dan pembentukan karakter antara peserta didik yang diajarkan menggunakan perangkat hasil pengembangan dengan yang menggunakan perangkat pembelajaran konvensional. Metode penelitian yang digunakan dalam penelitian ini adalah Research and Development (R&D) dengan mengacu pada model 4-D yang memiliki tahapan Define, Design, Develop dan Disseminate. Namun, tahapan Disseminate tidak dilaksanakan. Penelitian ini menghasilkan perangkat pembelajaran yang meliputi: silabus, rencanapelaksanaan pembelajaran, lembar kegiatan peserta didik, dan instrumen penilaian. Berdasarkan hasil penilaian oleh ahli, pendidik, dan teman sejawat, menunjukkan bahwa perangkat pembelajaran yang dikembangkan secara umum memiliki kategori “sangat baik”. Pembelajaran dengan menggunakan perangkat yang dikembangkan peneliti dapat membentuk karakter disiplin, tanggung jawab, kreatif, komunikatif dan teliti. Penggunaan perangkat pembelajaran hasil pengembangan juga dapat meningkatkan hasil belajar peserta didik.Berdasarkan hasil uji-t, maka terdapat perbedaan hasil belajar dan pembentukan karakter peserta didik yang diajarkan dengan perangkat hasil pengembangan dengan yang menggunakan perangkat pembelajaran konvensional.
BALANOCARPOL AND AMPELOPSIN H, TWO OLIGORESVERATROLS FROM STEM BARK OF Hopea odorata (DIPTEROCARPACEAE) Sri Atun; Nurfina Aznam; Retno Arianingrum; Masatake Niwa
Indonesian Journal of Chemistry Vol 6, No 3 (2006)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (270.912 KB) | DOI: 10.22146/ijc.21737

Abstract

Two oligoresveratrol, namely balanocarpol (2) and ampelopsin H (3) had been isolated from the steam bark of Hopea odorata (Dipterocarpaceae). The structures of these compounds were elucidated based on physical and spectroscopic data (MS, 1H and 13C NMR 1D and 2D). The activity of these compounds was evaluated against the 2-deoxyribose degradation induced by the hydroxyl radical generated via a Fenton-type reaction. The result showed that activity each compounds as radical hydroxyl scavenger of balanocarpol, and ampelopsin H with an IC50 1802.3 and 4840.0 μg/mL, respectively. Each compound showed low activity. Vitamin C (IC50 83.9 μg/mL) and butylated hydroxyl toluene (1328.0 μg/mL) were used as positif controls. These results suggest that oligoresveratrols from stem bark of H. odorata may be useful as potential sources of natural antioxidants.
BALANOCARPOL AND HEIMIOL A, TWO RESVERATROLS DIMER FROM STEM BARK Hopea mengarawan (Dipterocarpaceae) Sri Atun; Nurfina Aznam; Retno Arianingrum; Masatake Niwa
Indonesian Journal of Chemistry Vol 6, No 1 (2006)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (267.408 KB) | DOI: 10.22146/ijc.21777

Abstract

Isolation and structure elucidation of two resveratrols dimer, namely balanocarpol (1) and heimiol A (2) from stem bark of Hopea mengarawan had been done. The isolation of those compounds was carried out by chromatographic method and structure elucidation was performed by interpretation of spectroscopic data, including UV, IR,  1H and 13C NMR 1D and 2D, and FABMS.
BERAS ANALOG BERINDEKS GLIKEMIK RENDAH Mukti Syarifah; RISHA KURNIA DWI HARTANTI; muhamad arif nur rokhman; SITI NUR'AINI; siswanti ningsih; SRI ATUN
INOTEKS : Jurnal Inovasi Ilmu Pengetahuan, Teknologi, dan Seni Vol 23, No 2 (2019)
Publisher : LPPM UNY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/ino.v1i2.25534

Abstract

Talas (Colocasia esculenta) merupakan bahan pangan lokal umbi-umbian yang berotensi memiliki indeks glikemik rendah. Kandungan zat gizi yang tertinggi dalam talas adalah pati meskipun bervariasi antar kultivar talas (Hartati Prana, 2003). Dengan kandungan zat gizi yang tinggi, talas telah dibuat menjadi berbagai produk olahan seperti tepung talas dan kemudian dapat dibuat beras analog sebagai alternatif pangan berindeks glikemik rendah.Beras analog merupakan salah satu bentuk solusi yang dapat dikembangkan dalam mengatasi melimpahnya hasil panen baik dalam hal penggunaan sumber pangan baru ataupun untuk penganekaragaman pangan. Beras analog merupakan tiruan dari beras yang terbuat dari bahan-bahan seperti umbi- umbian dan serealia yang bentuk maupun komposisi gizinya mirip seperti beras (Slamet, 2012).Meskipun telah banyak beras analog di pasaran tetapi beras analog berbahan dasar umbi talas sangat berpotensi untuk dimanfaatkan sebagai salah satu produk pangan yang mencuri peluang penjualan di pasaran. Selain itu bahan dasar tersebut mudah ditemukan di wilayah Indonesia. Tumbuhan alami seperti wortel dengan pigmen berwarna oranye mengandung vitamin A yang dapat membantu meningkatkan penglihatan penderita diabetes. Selain itu bunga telang yang berwarna ungu-kebiruan dan daun kelor yang berwarna hijau mengandung antosianin dapat mencegah penyakit diabetes. Beras analog umbi talas dengan variasi warna dari ekstrak tumbuhan alami wortel, bunga telang, dan daun kelor menjadikan produk ini menarik, aman, alami dan cocok untuk dikonsumsi oleh penderita diabetes maupun semua lapisan masyarakat di Indonesia dalam pencegahan diabetes.
ENVIRONMENTAL LITERACY PROFILE OF STUDENTS IN NATURAL SCIENCE LEARNING-BASED EXPERIENTIAL Yasaroh, Sabila; Wilujeng, Insih; Atun, Sri; Indah Puspita Sari, Mega
Jurnal Pendidikan Matematika dan IPA Vol 14, No 1 (2023): January 2023
Publisher : Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (242.24 KB) | DOI: 10.26418/jpmipa.v14i1.51680

Abstract

The issue of environmental damage has been widely discussed in recent years in various parts of the world. Environmental literacy is very necessary for the prevention of environmental problems and for creating a healthy environment. One effective model to improve environmental literacy in schools is Experiential Learning, which invites students to design actions to care for the environment and actively participate in providing solutions to environmental problems. This study aims to determine the environmental literacy profile of students at SMPN 4 Depok in experiential learning-based science learning. This research is a quantitative descriptive study with a cluster random sampling technique, namely 50 students of classes VIIA and VII C. The data collection instrument used was 7 environmental literacy description test questions developed from 4 environmental literacy indicators (knowledge, attitudes, skills, and behavior). Data analysis was carried out quantitatively by calculating the percentage to determine the category of students' environmental literacy. Based on the results of data analysis, it was found that the average achievement of the knowledge aspect was 86.2%; the attitude aspect is 65.5%; the skill aspect is 82.5%, and the behavioral aspect is 71.4%. The average of these results shows the level of environmental literacy is 76.4% which is included in the high category. After knowing the environmental literacy profile of students, it is necessary to develop research on interesting and innovative media in science learning so that the four stages of Experiential Learning can run more optimally.
Pengaruh Modul Elektronik Terhadap Self-Regulated Learning dan Hasil Belajar Kognitif Pada Materi Ikatan Kimia Anugrah Anang Respati; Sri Atun
Jurnal Penelitian Pendidikan IPA Vol 9 No 5 (2023): May
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i5.2430

Abstract

This study aims to the effect of guided inquiry-based electronic modules on self-regulated learning and cognitive learning outcomes. The research design uses a quasi-experimental post-test only. This research was conducted on students of class X Natural Science in Yogyakarta using the cluster random sampling technique. The instrument used in this research is a self-regulated learning questionnaire and cognitive learning outcomes test. The data analysis technique uses Hotelling’s T-Test to test whether there are differences in self-regulated learning and cognitive learning outcomes with the implementation of electronic modules. The results show that the significance value is 0.002 < 0.05. This means that there is a difference in self-regulated learning and cognitive learning outcomes between students who use the guided inquiry-based electronic module and those who do not use the electronic module.
Antiangiogenesis Activity of Indonesian Local Black Garlic (Allium Sativum ‘Solo): Experiments and Bibliometric Analysis Retno Arianingrum; Nurfina Aznam; Sri Atun; S. Senam; Alya Rizkita Irwan; Nida Qurbaniah Juhara; Nadiya Fitri Anisa; Latifah Kurnia Devani
Indonesian Journal of Science and Technology Vol 8, No 3 (2023): (ONLINE FIRST) IJOST: December 2023
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/ijost.v8i3.63334

Abstract

Cancer is still one of the leading causes of death in the world. Angiogenesis is the formation of new blood vessels, which plays a vital role in the growth of cancer cells. As a result, inhibition of proangiogenic factors such as vascular epidermal growth factor (VEGF) could be used as a cancer treatment strategy. Black garlic (BG) is processed fresh garlic (Allium sativum L.) for several days under controlled high temperature and humidity. The research aims to investigate the effect of Indonesian local BG on antiangiogenic activity through in vivo and in silico studies. The in vivo test was carried out by observing the formation of new blood vessels using the Chorio-Allantoic Membrane Assay (CAM). The in silico study was performed by docking analysis of BG bioactive compounds on the VEGF receptor (VEGFR). The results showed that ethanol extract, ethyl acetate fraction, and n-hexane fraction of BG inhibit new vessel blood formation, with n-hexane fraction having the highest efficacy. The molecular docking assay indicated some similarities in the amino acids involved in the interaction between the BG bioactive compounds and the native ligand in binding to VEGFR. This similarity may lead to interference with VEGFR resulting in angiogenesis inhibition. The study suggests that BG has the potential to be developed as an anticancer agent, which might be through the mechanism of inhibiting the angiogenesis process
PEMBUATAN DAN KARAKTERISASI NANOPARTIKEL EKSTRAK ETANOL TEMU KUNCI (Boesenbergia pandurata) PADA BERBAGAI VARIASI KOMPOSISI ALGINAT Ghabby Maharani P; Sri Atun Sri Atun
Jurnal Elemen Kimia Vol 6, No 1 (2017): Volume 6 No 1 Tahun 2017
Publisher : Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tujuan dari penelitian ini adalah untuk mengetahui karakteristik nanopartikel dariekstrak etanol temu kunci (Boesenbergia pandurata) dan rasio optimal variasi alginat danCaCl2 untuk pembuatan nanopartikel temu kunci.Pembuatan ekstrak temu kunci dilakukanmenggunakan metode maserasi menggunakan etanol dilanjutkan evaporasi hingga terbentukekstrak kental. Koloid nanopartikel dibuat dengan mencampurkan ekstrak kental temu kuncidalam etanol, akuades, larutan alginat, dan larutan CaCl2. Terdapat 11 variasi komposisipada larutan alginat dan CaCl2 rasio (1:1); (3:1); (5:1); (1:2); (1:3); ( 1:4); (10:1); (6,66:1);(3,33:1); dan (2,5:1). Padatan dalam koloid nanopartikel dipisahkan menggunakan sentrifuge.Endapan dicuci dengan akuades dan disimpan dalam freezer. Koloid nanopartikel yangterbentuk dikarakterisasi menggunakan PSA dan zeta sizer untuk mengetahui ukuran partikeldan nilai zeta potensial. Padatan yang telah terbentuk dikarakterisasi menggunakan SEMuntuk mengetahui bentuk morfologi padatan tersebut. Karakterisasi menggunakan KLT untukmengetahui kesamaan senyawa antara nanopartikel ekstrak etanol temu kunci dan ekstraketanol temu kunci.Koloid nanopartikel yang berhasil dibuat berwarna coklat tua dan padatanberwarna coklat muda. Karakterisasi menggunakan PSA menunjukkan ukuran 339 - 877 nmsebanyak 95,2 % pada rasio konsentrasi asam alginat dan CaCl2 = 2,5:1. Nilai rerata zetapotensial adalah -72,1 mV. Hasil foto SEM menunjukkan partikel padatan berbentuk lonjongdengan ukuran 0,752 – 1,764 μm. Rf keenam sampel menunjukan hasil yang baik, yaitu Rf A= 0,66; Rf B = 0,61; Rf C = 0,60; Rf D = 0,60; Rf E = 0,65; dan Rf F = 0,71.
Co-Authors Abas Susilo Ade Sofiana Suryani Alfin, Riandi Althaaf, Nabila Tsabita Alya Rizkita Irwan Aminatun, Tien Ana Siti Nurjanah Anak Agung Gede Sugianthara Anisa Nur Khakim Anna Rakhmawati Anugrah Anang Respati Apriani, Nuni Arifudin Idrus Arthamena, Vegha Dwi Artina Diniaty Artina Diniaty, Artina Astuti Lestari Ayubi, Mizzan Azeeza, Sabira Nurul Azizah, Fidasari Nur Bian Ihda An Naila Darmono Dessy Kurniasari Dewi ANGGRAENI Dewi Anggraini Emilio L Ghisalberti Erlina Erlina Euis Holisotan Hakim Fajar Naqsyahbandi Fapriyan Wijoyo Mulyopratikno Fauji Agusta Ghabby Maharani P Habibatul Unayah Hadibah Kalor Heru Kuswanto Hurrahman, Mifta Ika Rosdiani Indah Puspita Sari, Mega Insih Wilujeng Jumaiyah, Wati Kamari, Azlan Kasyfi Rifqi Mouromadhoni Laila, Erni Latifah Kurnia Devani Lia Dewi Juliawaty Luthfi Fitri Frindryani Luthfia Ulva Irmita Maemonah, Maemonah Mamluaturrahmatika, Annisa Marpaung, Aisyatur Radhwa Masatake Niwa Mouromadhoni, Kasyfi Rifqi muhamad arif nur rokhman Muhamad Sarip Muhammad Ikhsan Muhammad Ikhsan Mukti Syarifah Mulyopratikno, Fapriyan Wijoyo Nadiya Fitri Anisa Nafakoti, Nadia Naffa Afkarina Izzata Dini Naqsyahbandi, Fajar Nelly Fadliyani Ni Putu Laksmi Cintya Dewi, Ni Putu Laksmi Cintya Nida Qurbaniah Juhara Niwa Masatake Nova Irawati Simatupang Nova Irawati Simatupang, Nova Irawati Nurfina Aznam Oky Pamungkas Pamungkas, Oky Patar Ariyanto Sitorus Purnamaningsih, Nur Aini Rahman, Nanang Rania Nur Farida Ratri Panggih Pangastuti Rayasari, Fitrian Retno Arianingrum RISHA KURNIA DWI HARTANTI Romadhoni, Siti Dzakiya Royani, Elmi Rusdiman Buhera S. Senam Sa'adah, Siti Imroatus Sabar Nurohman Sabar Nurohman Sangal, Aditi Sari, Winda Putri Permata Satriya, M. Agung Senam Senam Simbolon, Doly siswanti ningsih Siti Aisyah SITI NUR&#039;AINI Sjamsul Arifin Achmad Sogen, Jasintah Tagan Sri Lestari Sujangka, Arsyad Suryadi Prasetyo Susila Kristianingrum Suyanta Suyanta Tia Rachmatika Wahyuni Tonapa, Nely Wijoyo Mulyopratikno, Fapriyan Yana Maolana Syah Yani Sofiani Yasaroh, Sabila Yunitri, Ninik