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Hubungan antara Lama Terinfeksi Virus Penderita Hepatitis B dengan Indeks Eritrosit (MCV,MCH,MCHC) Septiani, Erna; Maruni Wiwin Diarti; Erlin Yustin Tatontos; Fihiruddin
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 2 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v3i2.166

Abstract

Background: Hepatitis B is an infectious disease that attacks the liver caused by the Hepatitis B virus. Hepatitis B virus infection is very infectious and is the main cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Hepatitis B can cause liver cirrhosis, where there is a change in the structure of the liver parenchyma resulting in a decrease in erythrocyte index levels. Objective: To determine the relationship between the duration of viral infection in hepatitis sufferers and the erythrocyte index (MCV, MCH, MCHC) Method: This research is an analytical observational study with a cross sectional approach and accidental sampling technique Results: Based on the results of the Kruskall Wallis test, the relationship between the duration of infection with the hepatitis B virus and the erythrocyte index (MCV, MCH, MCHV) resulted in MCV 75.50, MCH 17.97, MCHC 43.03 with a p value = 0.000 < 0.05. so it can be concluded that there is a relationship between the duration of infection with the hepatitis B virus and the erythrocyte index (MCV, MCH, MCHV) Conclusion: From the results of the analysis carried out, there is a relationship between the duration of infection with the hepatitis B virus and the erythrocyte index (MCV, MCH, MCHV)
Peningkatan Ksehatan Ibu Hamil dan Anak Sekolah dalam Pemanfaatan Tanaman Anti Infeksi Kecacingan Erlin Yustin Tatontos; Urip Urip
Sasambo: Jurnal Abdimas (Journal of Community Service) Vol. 5 No. 2 (2023): Mei
Publisher : Lembaga Penelitian dan Pemberdayaan Masyarakat (LITPAM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/sasambo.v5i2.1206

Abstract

Kecacingan adalah infeksi berbasis lingkungan dan termasuk penyakit yang terabaikan (Neglected Diseases), padahal  infeksi ini dapat menyebabkan anemia pada ibu hamil, gangguan pertumbuhan perkembangan anak dan penurunan fungsi kognitif.  Infeksi kecacingan seringkali diabaikan karena kurangnya pengetahuan tentang infeksi kecacingan dan mengkonsumsi obat cacing apabila telah menimbulkan gejala berat. Tujuan Pengabdian Kepada Masyarakat  adalah meningkatkan kesehatan ibu hamil dan anak sekolah dalam pemanfaatan tanaman anti infeksi kecacingan. Metode pelaksanaan kegiatan dengan promotif dan  preventif yaitu penyuluhan dan pelatihan pada sasaran ibu hamil, ibu menyusui dan kader kesehatan  berjumlah 50 orang di Posyandu Lingkungan Dasan Cermen Utara, serta siswa dan guru SD di  SDN 26 Cakranegara berjumlah 50 orang. Hasil Pengabdian Kepada Masyarakat sasaran di Posyandu Lingkungan Dasan Cermen Utara, pengetahuan meningkat dari 5 orang (10%) menjadi 50 orang (100%) dan sikap mendukung dari tidak ada 0% menjadi 45 orang (90%). Sasaran di SDN 26 Cakranegara , pengetahuan meningkat dari 10 orang (80%) menjadi 50 orang (100%) dan sikap mendukung dari 5 orang (10%) menjadi 50 orang (100%).Ibu hamil dan anak sekolah dengan pendampingan dapat melakukan kampanye kesehatan dengan Poster dan Booklet serta menanam tanaman anti infeksi kecacingan di Lingkungan dan Sekolah Improving the Health of Pregnant Women and School Children in the Utilization of Anti-Deworming Plants  Worms are environmental-based infections and include neglected diseases (Neglected Diseases), even though these infections can cause anemia in pregnant women, impaired growth and development of children and decreased cognitive function. Worm infections are often ignored because of a lack of knowledge about helminthic infections and taking worm medications when they cause severe symptoms. The aim of Community Service is to improve the health of pregnant women and school children by using anti-worm infection plants. The method of carrying out activities is promotive and preventive, namely counseling and training targeting pregnant women, nursing mothers and health cadres totaling 50 people at the Dasan Cermen Utara Environmental Posyandu, as well as elementary school students and teachers at SDN 26 Cakranegara totaling 50 people. The results of the Community Service target at Dasan Cermen Utara Environmental Posyandu, knowledge increased from 5 people (10%) to 50 people (100%) and supportive attitude from none 0% to 45 people (90%). Target at SDN 26 Cakranegara, knowledge increased from 10 people (80%) to 50 people (100%) and supportive attitude from 5 people (10%) to 50 people (100%). Pregnant women and school children with assistance can carry out health campaigns with posters and booklets and plant anti-worm infection plants in the environment and schools.
Gambaran Hasil Aglutinasi Pemeriksaan Widal Slide Metode Semi Kuantitatif pada Pasien Demam Tifoid di Puskesmas Kediri Khairunnisa; Yunan Jiwintarum; Ida Bagus Rai Wiadnya; Erlin Yustin Tatontos
Journal of Indonesia Laboratory Students (JILTS) Vol. 4 No. 1 (2025): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v4i1.184

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Latar Belakang : Pemeriksaan Widal slide telah menjadi salah satu metode diagnostik yang umum digunakan untuk mendeteksi infeksi demam tifoid. Pada pemeriksaan Widal slide metode kualitatif, volume sampel yang digunakan tidak terukur sehingga penentuan hasil titer ditentukan dengan melihat banyak atau sedikitnya aglutinasi yang terjadi. Hal ini dapat menyebabkan hasil positif palsu terutama karena variasi interpretasi dan faktor-faktor lain yang dapat mempengaruhi hasil. Dalam penentuan hasil titer Widal slide perlu melakukan pengukuran volume sampel dan melakukan validasi hasil dengan pengenceran serum atau plasma menggunakan metode semi kuantitatif, sehingga pembacaan hasil titer dapat dilakukan dengan melihat aglutinasi terakhir yang terbentuk. Tujuan Penelitian : Mengetahui gambaran hasil aglutinasi pemeriksaan Widal slide metode semi kuantitatif pada pasien demam tifoid di Puskesmas Kediri. Metode Penelitian : Penelitian ini merupakan penelitian deskriptif analitik dengan populasi sampel penelitian adalah pasien demam tifoid di Puskesmas Kediri. Sebanyak 20 sampel penelitian diambil dengan teknik accidental sampling. Pengumpulan data diperoleh dengan pemeriksaan Widal slide pada pasien demam tifoid dan didapatkan gambaran hasil aglutinasi pada pemeriksaan Widal slide metode kualitatif dan metode semi kuantitatif. Hasil Penelitian : Didapatkan gambaran hasil aglutinasi pemeriksaan Widal slide metode semi kuantitatif dengan titer 1/80 yang menunjukkan aglutinasi terakhir pada sampel 20 µl, titer 1/160 menunjukkan aglutinasi terakhir pada sampel 10 µl, titer 1/320 menunjukkan aglutinasi terakhir pada sampel 5 µl, dan titer 1/640 menunjukkan aglutinasi terakhir pada sampel 2,5 µl. Kesimpulan : Gambaran hasil aglutinasi Widal slide metode semi kuantitatif dapat memberikan hasil titer lebih tepat daripada menggunakan metode kualitatif.
Detection of Nicotine in Urine of Passive Smokers Exposed to Cigarette Smoke From Smoking and Non-Smoking Families Aolani, Almira Zaida; Fihiruddin, Fihiruddin; Urip, Urip; Tatontos, Erlin Yustin
Jurnal Analis Medika Biosains (JAMBS) Vol 12, No 2 (2025): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v12i2.459

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Passive smokers are vulnerable to nicotine exposure, which can increase the risk of health problems. Nicotine is a chemical compound in tobacco that causes dependence and can be detected in urine as metabolites like cotinine. This study aimed to detect nicotine in the urine of passive smokers exposed to cigarette smoke from smoking and non-smoking families in Genggelang Village. An analytical observational method with a cross-sectional design was used. The sample consisted of 24 respondents selected by purposive sampling, divided into two groups. Urine samples were tested using a nicotine test strip and analyzed descriptively. The results showed that among 12 passive smokers from smoking families, one respondent tested positive for nicotine. Meanwhile, all 12 respondents from non-smoking families tested negative. These findings indicate that passive smokers living with smoking families are still at risk of nicotine exposure through second hand smoke in the household environment.
Comparison of Fast and Time Blood Glucose Levels in Chronic Disease Management Program Patients (Proalnic) and Non-Prolanic with Diabetes Mellitus in Praya Health Center Aini, Miftahul; Tatontos, Erlin Yustin; Inayati, Nurul; Pauzi, Iswari
THRIVE Health Science Journal Vol. 1 No. 1 (2024): March
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v1i1.92

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Glucose is the most important carbohydrate which is mostly absorbed into the bloodstream as glucose and other sugars are converted into glucose in the liver. Blood glucose levels are closely related to DM. Prolanic (Chronic Disease Management Program) is a health service system that involves participants from Health Facilities and BPJS health in the context of health care for participants suffering from chronic diseases including diabetes mellitus to achieve optimal quality of life with cost-effective and efficient health services. To determine the comparison of fasting and intermittent blood glucose levels in prolanic and non-prolanic patients suffering from DM at Praya Health Center. : This type of research is Analytical Observation, the sample is taken purposively. A sample of 30 respondents, in this study were 15 respondents who took prolanis and 15 respondents who did not follow prolanis who had a history of diabetes mellitus and underwent blood glucose level checks at the UPTD BLUD Laboratory of Praya Health Center. Based on research that has been done, the average fasting blood glucose level in prolanis is 158 mg/dl and fasting glucose is 204 mg/dl. Meanwhile, non-prolanic fasting glucose levels are 156 mg/dl and fasting glucose levels are 204 mg/dl.
Uji Efektivitas Kombinasi Filtrat Daun Pepaya (Carica papaya) dan Daun Kemangi (Ocimum sanctum) Terhadap Daya Bunuh Kutu Kepala (Pediculus humanus capitis) Putu Dita Septiani; Urip; Erlin Yustin Tatontos; Ershandi Resnhaleksmana
Journal of Indonesia Laboratory Students (JILTS) Vol. 3 No. 1 (2024): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v3i1.78

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Latar belakang: Kutu kepala (Pediculus humanus capitis) merupakan suatu ektoparasit obligat penghisap darah yang terdapat pada rambut atau kepala manusia. Penggunaan bahan kimia memiliki dampak buruk bagi kesehatan manusia apabila digunakan secara tidak tepat. Oleh karena itu dibuat bahan alami pembasmi kutu kepala yaitu kombinasi filtrat daun pepaya (Carica papaya) dan daun kemangi (Ocimum sanctum) yang mudah ditemukan di masyarakat. Tujuan: Untuk mengetahui efektivitas kombinasi filtrat daun pepaya (Carica papaya) dan daun kemangi (Ocimum sanctum) terhadap daya bunuh kutu kepala (Pediculus humanus capitis). Metode: Penelitian ini bersifat quasi eksperiment dengan desain penelitian post test only control group desain. Populasi dan sampel adalah kutu kepala (Pediculus humanus capitis). Jumlah unit percobaan 27 (3 perlakuan dengan 9 kali replikasi) masing-masing petridish menggunakan 5 ekor kutu rambut sehingga jumlah sampel yang dibutuhkan adalah 135 ekor. Perlakuan menggunakan kombinasi filtrat daun pepaya (Carica papaya) dan daun kemangi (Ocimum sanctum) dengan perbandingan konsentrasi 30%:70%, 50%:50%, dan 70%:30% selama 60 menit serta kontrol negatif aquadest. Data yang dikumpulkan kemudian di analisis menggunakan uji Kruskal-wallis. Hasil penelitian: Didapatkan kematian kutu kepala kombinasi filtrat daun pepaya (Carica papaya) dan daun kemangi (Ocimum sanctum) perbandingan konsentrasi 30%:70% dengan persentase kematian sebesar 48%, kombinasi filtrat daun pepaya (Carica papaya) dan daun kemangi (Ocimum sanctum) perbandingan konsentrasi 50%:50% dengan persentase kematian sebesar 62%, dan kombinasi filtrat daun pepaya (Carica papaya) dan daun kemangi (Ocimum sanctum) perbandingan konsentrasi 70%:30% dengan persentase kematian sebesar 80%. Kesimpulan: Kombinasi filtrat daun pepaya (Carica papaya) dan daun kemangi (Ocimum sanctum) efektif terhadap daya bunuh kutu kepala (Pediculus humanus capitis) dengan nilai signifikan p = 0,000 < α =0,05. Kata kunci: Kematian, Filtrat, Alami, Daun Pepaya, Daun Kemangi, Kutu Kepala.
Fluktuasi Aktivitas Enzim SGOT dan SGPT pada Pasien Kanker Payudara yang Menjalani Kemoterapi di RSUD Provinsi NTB Ananda, Fadila Rizki; Tatontos, Erlin Yustin; Fihiruddin, Fihiruddin
Jaringan Laboratorium Medis Vol. 7 No. 2 (2025): November 2025
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v7i2.13322

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Chemotherapy is one of the primary treatment for breast cancer. Despite its effectiveness, chemotherapy has the potential to cause hepatotoxicity due to drug metabolism in the liver. This condition is generally indicated by elevated levels of SGOT and SGPT enzymes. Liver enzyme monitoring is essential to assess hepatocellular function throughout the course of therapy. This research aims to determine fluctuations in SGOT and SGPT enzyme activity in breast cancer patient undergoing chemotherapy at the NTB Provincial Hospital, and describe the pattern of changes in enzyme values based on the frequency of chemotherapy cycles. An analytical observational study with a cross-sectional approach was employed. Samples were selected purposively based on the medical records of breast cancer patients who underwent 1 to 6 cycles of chemotherapy between January and December 2024. Data were analyzed descriptively based on the distribution and the average of SGOT and SGPT enzyme levels. The results showed fluctuating SGOT and SGPT levels across different chemotherapy cycles. There was no consistent pattern of increase in enzyme activity based on chemotherapy frequency.  The average SGOT levels from cycle 1 to 6 were 24, 28, 27, 30, 33, and 24 IU/L, while the average SGPT levels were 35, 27, 29, 25, 29, and 29 IU/L, with a range of SGOT values of 13-404 IU/L and SGPT with a range of 5-304 IU/L. most enzyme values remained within normal range. It was concluded that chemotherapy frequency did not show a consistent association with increased SGOT and SGPT activity. These research emphasize the importance of routine monitoring of liver function during each chemotherapy cycle, so that potential hepatotoxicity can be adjusted according to the patient condition.  
Analysis of Circadian Rhytme Variations on Glucose Examination Results Rahmani, Putri Ziddanur; Jiwintarum, Yunan; Tatontos, Erlin Yustin; Pauzi, Iswari
THRIVE Health Science Journal Vol. 1 No. 2 (2024): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v1i2.234

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Background: Circadian rhythm is a term used to describe the 24-hour physiological rhythm of organisms. According to Minister of Health Regulation no. 43 of 2013 concerning How to Organize a Good Clinical Laboratory, the Circadian rhythm variation is explained in the body as levels of certain substances change from time to time. Changes in substance levels that are influenced by time can be cyclical, such as daily cycles (diurnal variations), monthly cycles (menstruation), or linear/straight lines, such as age. Classic experiments using a 72-hour glucose clamp methodology, demonstrated that humans exhibit a robust Circadian rhythm in insulin secretion, independent of food and glycemia. Additionally, a cell-autonomous Circadian clock appears to oversee the diurnal rhythm in glucose-induced insulin secretion.Research Objectives: Knowing the analysis of Circadian rhythm variations on glucose examination results. Research Methods: Analytical observational analysis using cross sectional methods and purposive sampling techniques. The sample population of applied TLM undergraduate students class of 2020 had blood serum taken and using the Slovin formula to determine the sample size, 36 samples were obtained with respondents without a history of diabetes mellitus. Data analysis used the Paired t-test statistical test. Research Result: The results obtained from the examination of the average glucose level at the time of sampling in the morning were 80.25 mg/dl, in the afternoon 96.5 mg/dl, and in the evening 85.91 mg/dl. The results of the paired t-test statistical analysis obtained Sig. (2-tailed) or p 0.010 means p < 0.05 there is a difference in the average glucose results at the time of sampling in the morning and afternoon and Sig. (2-tailed) or p 0.115 means p > 0.05 there is no difference in the average glucose test results at the time of sampling in the morning and evening. Conclusion:  Blood glucose levels taken in the morning have lower average levels than during the day and evening.
Infeksi Malaria dan Status Gizi Balita Pasca Gempa Tatontos, Erlin Yustin; Urip, Urip
Bioscientist : Jurnal Ilmiah Biologi Vol. 11 No. 2 (2023): December
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v11i2.9141

Abstract

After the earthquake that occurred on Lombok Island during August 2018, malaria appeared again, especially in West Lombok Regency. The number of cases recorded was 753 people infected with malaria, including babies and pregnant women. Problems that arose after the earthquake on Lombok Island among babies and toddlers were malnutrition, including Insufficient Breast Milk (IBM) and Complementary Foods (CF) due to separation from their mothers. The aim of this research was to determine malaria infection and nutritional status of children under five in the earthquake-affected area in West Lombok Regency. The research method uses a qualitative approach. Data collection used was in-depth interviews, observation, and document study. Data analysis with the Epi info test. The results obtained were that the number of cases of malaria infection in the earthquake-affected areas in West Lombok Regency, especially the Penimbung Community Health Center, in 2018 was 753 cases and in 2019 there were 299 cases. Nutritional status in 2018 and 2019: 5,775 people with good nutrition: 710 people with poor nutrition, and 6 people with Low Birth Weight (LBW). The conclusion that can be drawn is that there is no relationship between post-earthquake malaria and the nutritional status of children under five.
The Density of Aedes aegypti Larvae Density and the Incidence of Dengue Hemorrhagic Fever in the Pesingahan Environment, Pagesangan Barat Village, Mataram Urip, Urip; Rizki, Kurnia; Tatontos, Erlin Yustin; Gunarti, Gunarti; Kholik, Kholik
JURNAL INFO KESEHATAN Vol 21 No 1 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss1.986

Abstract

Dengue hemorrhagic fever remains a public health concern in West Nusa Tenggara Province, with the majority of cases occurring in Mataram City and the Pesinggahan Environment of West Pagesangan Village. The density of Aedes aegypti larvae as disease vectors has a strong influence on the high incidence of cases and the spread of dengue hemorrhagic fever. The objective of this study was to identify if there was a relation between the density of Aedes aegypti larvae and the rate of dengue hemorrhagic fever in the Pesinggahan Environment of Pagesangan Barat Village. This study is an analytic observational study with a cross-sectional design. This study's sample size was 56 houses. The data collected included information on the density of Aedes aegypti larvae and the incidence rate of dengue hemorrhagic fever in the Pesinggahan Environment of Pagesangan Barat Village over the previous year. Descriptive analysis was used to examine data on the density of Aedes aegypti larvae and the incidence rate of dengue hemorrhagic fever in the Pesinggahan environment. The findings revealed that the density of Aedes aegypti larvae was high (Density Figure (DF) = 6), as was the incidence rate of dengue hemorrhagic fever (0.39%). The statistical analysis between the density of A. aegypti larvae and the incidence rate of dengue hemorrhagic fever in the Pesinggahan Environment with the chi square test demonstrated indicate that p-value = 0.000 < alpha = 0.05. Based on the results of the study, there was a relationship between the density of A. aegypti larvae and the incidence rate of dengue hemorrhagic fever in Pesinggahan, Pagesangan Barat Village. Further research is required regarding the detection of the dengue virus transmitted by A. aegypti mosquitoes to their offspring (transovarial).
Co-Authors . Kholik Aden Turmuji Aeni Halawiya Agrijanti, Agrijanti Aini, Aini Ananda, Fadila Rizki Anggun Sari Mianti Anky Frasatya Aolani, Almira Zaida Ari Khusuma Aurira Thrisna Dwi Aprianti Ayu Rosita Dendi Arisandi Dera Suci Elmaria Dewi, Lale Budi Kusuma Dramawan, Awan Eliza, Ida Eliza, Ida Erna Kristinawati Ershandi Resnhaleksmana Feni Wahyuni Fihiruddin, Fihiruddin Getas, I Wayan Gunarti Gunarti Gunarti Gunarti Gunarti, Gunarti Hana Fatinah I Gede Arya Santika Arya I Gusti Ayu Ambarawati Iswara Sesa I Nyoman Purna I Wayan Getas I Wayan Sali Ida Eliza IGAN Danuyanti Iswari Pauzi Iswari Pauzi Khairunnisa Kholik, Kholik Kristinawati, Erna Kurnia Rizki Lalu Sri Gede Lalu Sri Gede Lu’lu’il Adawiyah Maruni wiwin Danuarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maswan, Moch Miftahul Aini, Miftahul Mutiara Rachmawati Suseno Nanda Yuniza Pratiwi Ni Nengah Yunita Nurul Inayati Nurul Inayati Nurul Inayati Nurul Inayati Nurul Inayati Nurul Inayati Nurul Inayati Pauzi, Iswari Putu Dita Septiani Putu Femila Rahmani, Putri Ziddanur RAI WIADNYA, IDA BAGUS Reshnleksmana, Ersandhi Riska Novitasari Rizki, Kurnia Rohmi Rohmi Rohmi, Rohmi Salleh, Mohd Nazil Septiani, Erna Septiawan, Dandi Siti zaetun Siti Zaetun, Siti sofiatummina Sri Hartuti Thomas Tandi Manu Titin Emilia Nirmala Sari Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip Urip, Urip Yuliana Wardani Yunan Jiwintarum Yunan Jiwintarum Yunan Jiwintarum Yunan Jiwintarum Zainal Fikri